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Wyświetlanie 1-3 z 3
Tytuł:
Ocena kliniczna wpływu bewacyzumabu w kroplach na morfologię i funkcję pęcherzyka filtracyjnego z objawami niewydolności
Clinical evaluation of the effect of topical bevacizumab on morphology and function of filtering bleb with failure symptoms
Autorzy:
Kuna, Anna
Żarnowski, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1927538.pdf
Data publikacji:
2020
Wydawca:
Medical Education
Tematy:
failure of filtering bleb
filtering bleb
vessel area
Opis:
Cel pracy: Ocena przydatności bewacyzumabu w kroplach u pacjentów poddanych trabekulektomii w celu zahamowania gojenia rany pooperacyjnej. Materiał i metody: 53 osoby po zabiegu przeciwjaskrowym z wytworzeniem pęcherzyka filtracyjnego, u których doszło do wczesnej, pooperacyjnej niewydolności pęcherzyka kwalifikującej się do zastosowania bewacyzumabu w kroplach. Pełnej analizie statystycznej poddano 30 pacjentów, którzy poza badaniem ciśnienia wewnątrzgałkowego, badaniem w lampie szczelinowej i oceną pęcherzyka w skali MBGS, dodatkowo wykonane mieli zdjęcia fotograficzne pęcherzyka, na podstawie których dokonano pełnej analizy morfologicznej pęcherzyka. Wyniki: Całkowity sukces po 6 miesiącach, bez stosowania leków przeciwjaskrowych (ciśnienie wewnątrzgałkowe końcowe <18 mmHg i obniżenie ciśnienia wewnątrzgałkowego wyjściowego o 30%) osiągnięto u 18 pacjentów (60%). Częściowy sukces (obniżenie ciśnienia wewnątrzgałkowego wyjściowego o 30%) osiągnięto u 19 pacjentów (63,3%). Wnioski: Bewacyzumab to skuteczna i bezpieczna terapia pomocnicza dla miejscowych glikokortykosteroidów w leczeniu wczesnej pooperacyjnej niewydolności pęcherzyka poprzez zmniejszenie unaczynienia na jego powierzchni. Ocena średniej powierzchni naczyń pęcherzyka na zdjęciu fotograficznym, dokonana przy użyciu programu ImageJ, koreluje z oceną pęcherzyka w skali MBGS.
Objectives: Evaluation of bevacizumab drops in patients undergoing trabeculectomy in order to inhibit postoperative wound healing. Material and methods: A total of 53 patients treated surgically for glaucoma. The anti-glaucoma procedures with the creation of a filtering bleb were performed. The patients developed early postoperative bleb insufficiency qualifying them for the use of bevacizumab drops. Thirty were completely statistically analyzed; intraocular pressure and slit lamp examinations were performed and the bleb was assessed according to the MBGS. Additionally, photographs of the filtering blebs were made, which were used for bleb morphological analysis. Results: Total success, after 6 months, without using anti-glaucoma drugs (intraocular pressure < 18 mmHg and a decrease in baseline intraocular pressure by 30%) was observed in 18 patients (60%). Partial success, after 6 months, without using anti-glaucoma drugs (decrease in baseline intraocular pressure by 30%) was achieved in 19 patients (63.3%). Conclusions: Bevacizumab is an effective and safe adjunctive therapy with topical steroids for the treatment of early postoperative filtering bleb insufficiency as it reduces innervation on the bleb surface. Evaluation of the mean surface of bleb vessels on photographs, using ImageJ (Wayne Rasband), correlates with MBGS evaluation of filtering blebs.
Źródło:
OphthaTherapy; 2020, 7, 3; 203-212
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Malaria i bezpieczeństwo w Afryce
Malaria and security in Africa
Autorzy:
Kuna, Anna
Powiązania:
https://bibliotekanauki.pl/articles/567132.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie. Instytut Nauk Politycznych
Tematy:
malaria
gruźlica i HIV/AIDS w Afryce
bezpieczeństwo w Afryce
walka z chorobami w Afryce
malaria w Angoli
tuberculosis and HIV/AIDS in Africa
security in Africa
combating with diseases in Africa
malaria in Angola
Opis:
Malaria, along with tuberculosis and HIV/AIDS is one of the three most dangerous infectious diseases in the World. 200 million people are affected annually and 600 thousand die as a result of the disease. Many governmental and non-governmental organizations combat malaria in various ways by promoting prophylaxis and effective treatment of the disease. Because of its prevalence in over 100 countries, malaria has enormous impact on the economies of these regions, with expenditures on treatment amounting to 40% of total health care costs. In the medical field, effective treatment of malaria remains a challenge because, since 2008, resistance to every available drug has been described. Malaria has been treated for ages as a real threat to military operations, causing service unfitness more often than trauma in combat. In the economic aspect, malaria is a great burden for the endemic areas and losses in whole Africa amount to $100 million GDP per year. Low-income households spend up to 28% of their earnings. Modernization and expansion of agriculture without increasing transmission of malaria also remains a challenge. In conclusion, effective combating malaria will allow economic growth and strengthening of security in whole Africa. Cooperation of international and national organizations with basic healthcare providers is crucial in order for prevention and treatment to reach average people.
Źródło:
Forum Politologiczne; 2014, 16 - Konteksty bezpieczeństwa w Afryce. Problemy globalne, sektorowe, regionalne, lokalne; 297-313
1734-1698
Pojawia się w:
Forum Politologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Jak zobaczyć informację, czyli różnorodne funkcje mapy w procesie wymiany informacji
Autorzy:
Kuna, Jakub
Rzuciło, Anna
Powiązania:
https://bibliotekanauki.pl/articles/962136.pdf
Data publikacji:
2015
Wydawca:
Uniwersytet Marii Curie-Skłodowskiej. Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
Opis:
Along with the development of the modern communication techniques communication and the information storage, the amount of data building-up from all around is increasing at an alarming rate. A significant part of these data is of spatial nature, which means that identifying them on the surface of the Earth is possible. This, so called ‘spatial data’, can also include information about objects’ geometry, location in the defined reference system, as well as characteristics of spatial relations that can occur between particular object and other objects. Therefore we can interpret the term ‘geographic information’ as an information about natural or abstractive objects as well as phenomena and processes that occur on the Earths’ surface.There are many sources of spatial data, including: satellite and aerial imaging, field measurements, maps and other databases, etc. The timeliness of the spatial data is diverse and depends on many factors. In comparison with a life of an average human, large amount of spatial data is up-to-date for a long period: for instance, mountain ranges change so slow that it is imperceptible. Decades are needed to percept substantial changes in the density of roads or railways. Some data, like administrative boundaries, have specified chronological durability – they are valid from the moment they were introduced by one legislation until they would be cancelled by another legislation. However, crucial part of the spatial data get out of date very quickly - in matter of months, days, hours – catastrophic events are the mayor reason of the spatial information redundancy. The abstract character of some information is another problem that often arises from collecting spatial data. For example population density – what it really is, how should it be counted or what is the reason for doing it? While presenting spatial information, a cartographer must face a lot of issues similar to those mentioned in this paper.Since the early 60’s there is a big dispute among cartographers on the definition of map and its role in the process of the information transfer. The most frequently advanced thesis describes maps as sources, carriers, models, visualizations and even specific language of information transfer. Maps simultaneously collect, describe (encode), order (give a hierarchy), select, synthesize, visualize, communicate and archive information about qualitative or quantitative characteristics of geographical phenomena (real or abstract) in the form of a notional spatial model. Similarly to a language, a map is a dynamic creation, which changes along with time, space and function. Model arising in the mind of an editor (map creator) subjects to the laws of determinism and, as such, is burdened with a number of factors (history, language, culture, environment, etc.). Map made in accordance with the best possible knowledge and the most advanced printing techniques for a given historical period, is a reflection of the civilization development which shows how the reality was perceived by the maps‘ creators.The stages of selection, synthesis and visualization of information done by map editor, lead to a new quality of communication, adapted to the recipients’ mental and physical capabilities (age, knowledge, efficiency of response to stimuli). Despite this, the model formed in the mind of the maps’ recipient is always secondary, burdened with a different set of conditions and, in consequence, may significantly differ from the original model.
Źródło:
Folia Bibliologica; 2015, 57
2449-8246
1230-2376
Pojawia się w:
Folia Bibliologica
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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