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    Wyświetlanie 1-11 z 11
    Tytuł:
    Current clinical management of malignant melanoma – diagnosis process and innovative therapies
    Autorzy:
    Kwiatkowski, Stanisław
    Przystupski, Dawid
    Kotowski, Krzysztof
    Kolasińska, Karolina
    Saczko, Jolanta
    Kulbacka, Julita
    Powiązania:
    https://bibliotekanauki.pl/articles/1177464.pdf
    Data publikacji:
    2018
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    AJCC
    Melanoma malignum
    dabrafenib
    electrochemotherapy
    ipilimumab
    melanoma
    melanoma staging
    pembrolizumab
    photodynamic therapy
    vemurafenib
    Opis:
    Malignant melanoma is a highly invasive cancer which derives from neuroectodermic melanocytic cells. It is characterized by the highest frequency of cases in both sexes and all age groups. High metastatic potential of melanoma and its multidrug resistance might be a significant problem in the treatment. Permanent and complete remissions are rare, while the 5-year survival rate remains relatively low. In the last years there has been a breakthrough in the systemic therapy of malignant melanoma. Modern drugs have revolutionized previous therapeutic management of melanoma. As part of therapeutic programs, new medicines are available: dabrafenib, ipilimumab, pembrolizumab, trametinib and vemurafenib. The following paper presents current clinical management standards for melanoma diagnoses, based on the widely accepted scientific data and expert experience - with emphasis on modern methods of treatment of this cancer.
    Źródło:
    World Scientific News; 2018, 102; 30-46
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    A review of current literature on the diagnosis, prophylaxis and treatment of HIV/AIDS
    Autorzy:
    Sobieski, Mateusz
    Przystupski, Dawid
    Korzeniewska, Aleksandra
    Kwiatkowski, Stanisław
    Górska, Agata
    Kotowski, Krzysztof
    Baczyńska, Dagmara
    Powiązania:
    https://bibliotekanauki.pl/articles/1162996.pdf
    Data publikacji:
    2018
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    AIDS
    AIDS-related cancers
    HIV
    cART
    Opis:
    Acquired immunodeficiency syndrome (AIDS) is a spectrum of various diseases associated with the human immunodeficiency virus (HIV) infection. AIDS is one of the most common infectious illness with 1.8 million of new cases and approximately 36.7 million living with HIV. AIDS becomes a worldwide problem and due to rising number of HIV-positive patients, the appropriate medical care is needed. This article takes into consideration the current information about pathogenesis of HIV infection, clinical and biochemical symptoms, diagnosis, prophylaxis and treatment the disease. Furthermore, the article describes the side effects of the treatment, the methods of their diagnosis and prevalence, and focuses on the psychological problems of HIV-positive people.
    Źródło:
    World Scientific News; 2018, 110; 129-146
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    An overview of paraneoplastic neurological syndromes – pathophysiology and clinical insight
    Autorzy:
    Kwiatkowski, Stanisław
    Kolasińska, Karolina
    Knap, Bartosz
    Przystupski, Dawid
    Kotowski, Krzysztof
    Bartosik, Weronika
    Kulbacka, Julita
    Powiązania:
    https://bibliotekanauki.pl/articles/1163959.pdf
    Data publikacji:
    2018
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    dermatomyositis
    encephalitis
    opsoclonus-myoclonus
    paraneoplastic neurological syndromes
    Opis:
    Paraneoplastic syndrome (PS) is a dysfunction of organs or systems, associated with neoplastic disease, but not related to the local growth of tumor, metastasis or adverse anti-cancer drugs reactions. Neurological paraneoplastic syndromes (NPSs) may affect every region of a human nervous system - both central, peripheral, and/or autonomic nervous system. The symptoms are caused by a neoplastic process in other organ or system. PNSs usually precede the development of cancer for months or even years, and can be therefore useful diagnostic markers of cancer. They present an autoimmune background associated with the response of the immune system against cancer cells. In the blood serum and cerebrospinal fluid of patients with PNS appear onconeural antibodies, reacting with tumor antigens and the brain, the spinal cord and peripheral ganglia antigens. Many authors emphasize the significance of paraneoplastic syndromes in the modern oncology. Due to this reason, the knowledge of paraneoplastic syndromes and their mechanisms is very important in the contemporary medicine. The purpose of this research review is to summarize the information about the clinical features of the most common PNSs and the pathological mechanisms of their development.
    Źródło:
    World Scientific News; 2018, 108; 87-98
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Contemporary management and novel therapies in ovarian cancer – literature review
    Autorzy:
    Kotowski, Krzysztof
    Przystupski, Dawid
    Kwiatkowski, Stanisław
    Kolasińska, Karolina
    Bartosik, Weronika
    Górska, Agata
    Saczko, Jolanta
    Baczyńska, Dagmara
    Kulbacka, Julita
    Powiązania:
    https://bibliotekanauki.pl/articles/1162168.pdf
    Data publikacji:
    2018
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Anti-VEGF monoclonal IgG1 antibody
    Interval Cytoreductive Surgery
    Interval Debuking Surgery
    bevacizumab
    electrochemotherapy
    hormone therapy
    immunotherapy
    ovarian cancer
    photodynamic therapy
    Opis:
    Ovarian cancer is characterized by an extremely poor prognosis in women with an advanced stage of this carcinoma. In United States every year 20,000 women are diagnosed with ovarian cancer. It is the fifth most frequent cause of death from cancer in females and the most common cause of death for 15 years after diagnosis in women with stage III-IV tumors. Among ovarian neoplasms the most frequent are surface epithelial-stromal tumors. Moreover, non-epithelial ovarian tumors are distinguished. This group matters 10% of patients with diagnosed ovarian tumors. Due to a huge variety of ovarian tumors, the following work focuses mainly on the current clinical treatment of the epithelial ovarian cancer. The following paper summarizes current clinical treatment of epithelial ovarian cancer, including surgical procedure, chemo- and immunotherapy including modern therapeutic approaches.
    Źródło:
    World Scientific News; 2018, 111; 51-63
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Chevkinite-group minerals in Poland
    Autorzy:
    Nejbert, Krzysztof
    Bagiński, Bogusław
    Kotowski, Jakub
    Jokubauskas, Petras
    Jurewicz, Edyta
    Macdonald, Ray
    Powiązania:
    https://bibliotekanauki.pl/articles/138930.pdf
    Data publikacji:
    2020
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    Chevkinite group minerals
    Chevkinite-(Ce)
    Perrierite-(Ce)
    mineral chemistry
    petrological significance
    Polska
    minerały
    chemia minerałów
    znaczenie petrologiczne
    Polska
    Opis:
    The chevkinite group of minerals are REE,Ti-silicates increasingly recognized as widespread accessory phases in a wide range of igneous and metamorphic parageneses. Members of the group are here recorded from five localities in Poland: a two-pyroxene andesite from the Kłodzko-Złoty Stok intrusion, a trachyandesite intrusion north of the Pieniny Mountains, a rapakivi-type granite from the Krasnopol intrusion, an anorthosite from the Suwałki Anorthosite Massif, and nepheline syenite from the Ełk syenite massif. Specific members found are chevkinite-(Ce), perrierite-(Ce) and, potentially, the Al-dominant analogue of perrierite-(Ce). The case is made that chevkinite-group minerals will, through systematic investigation, be found in a wide range of Polish igneous and metamorphic rocks.
    Źródło:
    Acta Geologica Polonica; 2020, 70, 1; 97-106
    0001-5709
    Pojawia się w:
    Acta Geologica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Mollusc faunas of lake deposits in Gorzów Wielkopolski (NW Poland) as an indicator of environmental changes during Eemian and Early Weichselian
    Autorzy:
    Alexandrowicz, Witold Paweł
    Skoczylas, Sylwia
    Sobczyk, Artur
    Stefaniak, Krzysztof
    Kotowski, Adam
    Przybylski, Bogusław
    Ciszek, Dariusz
    Badura, Janusz
    Urbański, Krzysztof
    Powiązania:
    https://bibliotekanauki.pl/articles/2060111.pdf
    Data publikacji:
    2021
    Wydawca:
    Państwowy Instytut Geologiczny – Państwowy Instytut Badawczy
    Tematy:
    palaeolake
    malacofauna
    environmental changes
    Eemian interglacial
    Early Weichselian
    NW Poland
    Opis:
    During the construction of the S-3 road near Gorzów Wielkopolski, a sedimentary succession of the Eemian Interglacial and the older part of the Weichselian Glaciation were exposed. The succession, ~22 m thick, consists of lacustrine and fluvioglacial deposits. Lake sediments, mainly calcareous gyttja with peat intercalations, represent the infills of two palaeolakes. The almost complete skeleton of a forest rhinoceros, Stephanorhinus kirchbergensis, and a bone of the fallow deer Dama dama were found in the older lake deposits. Mollusc shells were numerous in both lake sequences, analysis of which revealed two types of assemblage, representing the coastal, littoral zone of a shallow lake with a muddy bottom. The sequence of mollusc communities observed in vertical succession allowed reconstruction of environmental changes during deposition. Several hydrological changes have been recognized within the palaeolake, especially water level fluctuations probably due to climate change.
    Źródło:
    Geological Quarterly; 2021, 65, 3; 65: 36
    1641-7291
    Pojawia się w:
    Geological Quarterly
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-11 z 11

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