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    Wyświetlanie 1-13 z 13
    Tytuł:
    The induction of bcl-2 gene expression in human lymphocytes in vitro
    Indukcja ekspresji genu bcl-2 w limfocytach czlowieka hodowanych in vitro
    Autorzy:
    Kocki, J
    Rozynkowa, D.
    Powiązania:
    https://bibliotekanauki.pl/articles/68508.pdf
    Data publikacji:
    1994
    Wydawca:
    Polska Akademia Nauk. Instytut Genetyki Roślin PAN
    Tematy:
    gen bcl2
    limfocyty
    ekspresja genow
    genetyka czlowieka
    cykl komorkowy
    hodowla in vitro
    Źródło:
    Genetica Polonica; 1994, 35, 1-2; 115-125
    0016-6715
    Pojawia się w:
    Genetica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evolution and application of new genetic techniques - from nucleic acids via microarrays to CRISPR
    Autorzy:
    Kocki, J.
    Bogucka-Kocka, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/283868.pdf
    Data publikacji:
    2018
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    nucleic acids
    microarrays
    CRISPR
    Źródło:
    Engineering of Biomaterials; 2018, 21, 148; 80
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Cytokine profiles of dendritic cells (DCs) during infection with bovine leukaemia virus (BLV)
    Autorzy:
    Iwan, E.
    Szczotka, M.
    Kocki, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/31049.pdf
    Data publikacji:
    2017
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    BLV is an agent of enzootic bovine leukaemia (EBL), an infectious disease affecting cattle worldwide. BLV infection has been associated with immune system disorders and discrepancies in the cytokine network. The significance of dendritic cells in the pathogenesis of BLV infection is largely unknown, but considering their fundamental role in immune response it may be crucial. Dcs precursors were isolated with the use of immunomagnetic beads from BLV-infected and BLV-free cows. From these precursors cultures of monocyte derived dendritic cells (MoDCs) were generated with the use of a cytokine cocktail (IL-4 and GM-CSF). Additionally, parallel DCs from BLV-negative animals were infected in vitro. The level of cytokines: IL-6, IL-10, IL-12(p40), IL-12(p70) was determined in DC cultures: infected in vitro, originating from naturally infected cattle and BLV-free cattle. The investigation showed significant changes in almost all analyzed populations of BLV-infected Dcs. Cytokine profiles of blood MoDCs indicated activation of these groups during infection. In the case of spleen MoDCs and lymph node MoDCs a decrease in production of IL-12(p40) and IL-12(p70) in favour of IL-6 and IL-10 was noted, suggesting promotion of BLV infection development.
    Źródło:
    Polish Journal of Veterinary Sciences; 2017, 20, 2
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Determination of cytokine profiles in populations of dendritic cells from cattle infected with bovine leukaemia virus
    Autorzy:
    Iwan, E.
    Szczotka, M.
    Kocki, J.
    Pluta, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087622.pdf
    Data publikacji:
    2018
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    bovine leukaemia virus
    dendritic cells
    cytokines
    Źródło:
    Polish Journal of Veterinary Sciences; 2018, 21, 4; 681-690
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Determination of telomere length and telomerase activity in cattle infected with bovine leukaemia virus (BLV)
    Autorzy:
    Szczotka, M.
    Kocki, J.
    Iwan, E.
    Pluta, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087507.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    bovine leukaemia virus
    telomerase
    telomeres
    Źródło:
    Polish Journal of Veterinary Sciences; 2019, 2; 391-403
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    MicroRNAs in atherosclerosis: altered expression and diagnostic potential
    Autorzy:
    Bogucka-Kocka, A.
    Zalewski, D.
    Ruszel, K.
    Kocki, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/286064.pdf
    Data publikacji:
    2018
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    RNA
    atherosclerosis
    diseases
    Źródło:
    Engineering of Biomaterials; 2018, 21, 148; 76
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    CLA - właściwości prozdrowotne
    CLA - health benefits/health promoting properties
    Autorzy:
    Karwat, J.
    Gil-Kulik, P.
    Kotula, L.
    Niedojadlo, A.
    Kocki, J.
    Sawiuk, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/4410.pdf
    Data publikacji:
    2013
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    sprzezony kwas linolowy
    wlasciwosci prozdrowotne
    otylosc
    suplementy diety
    odchudzanie
    Źródło:
    Medycyna Ogólna i Nauki o Zdrowiu; 2013, 19(48), 4
    2083-4543
    Pojawia się w:
    Medycyna Ogólna i Nauki o Zdrowiu
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Clonal chromosome abnormalities in B-cell chronic lymphocytic leukemia
    Klonalne aberracje chromosomów u chorych z przewlekłą białaczką B-limfocytową
    Klonovye aberracii khromosom u bolnykh s khronicheskojj B-limfocitnojj lejjkemiejj
    Autorzy:
    Rozynkowa, D.
    Rupniewska, Z.M.
    Stepien, J.
    Drabik, B.
    Antosz, H.
    Kocki, J.
    Gorski, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/67965.pdf
    Data publikacji:
    1991
    Wydawca:
    Polska Akademia Nauk. Instytut Genetyki Roślin PAN
    Źródło:
    Genetica Polonica; 1991, 32, 3
    0016-6715
    Pojawia się w:
    Genetica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    An evaluation of the genetic conditioning of evoking pain
    Autorzy:
    Pacian, A.B.
    Kocki, J.
    Pacian, J.
    Kaczoruk, M.
    Bylina, M.
    Kaczor-Szkodny, P.
    Galińska, E.M.
    Kulik, T.
    Panasiuk, L.
    Powiązania:
    https://bibliotekanauki.pl/articles/2085535.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    genetics
    chronic pain
    genes expression
    DRD1 gene
    molecular research
    Opis:
    Introduction and objective. Pain is an integral element of the pathogenic process and sometimes determines its course. Disorders in pain sensation, as well as its lack, the pain threshold, and variability in sensation of the same pain stimuli as more or less intensive by different persons, may be genetically conditioned. The aim of the study is to examine genes in pathogenesis of chronic pain. Materials and method. The study was conducted in a specially selected group of 31 persons: study group – 20 patients with chronic pain, and control group – 11 healthy individuals who did not experience pain. The control group of 11 healthy persons, compared with the study group, was the catalyst for determining the relative quantification (RQ) of gene expression. Biological material in the form of venous blood was collected from the study participants into the tubes containing anticoagulant EDTA KE/2.7 ml (ethylenediaminetetraacetic acid), preventing extracorporeal blood clotting. Results. Analysis of expression of the examined genes showed over-expression of the DRD1 gene in patients experiencing chronic pain, which means that in these patients an increased number of dopamine D1 receptors encoded by this gene should be expected. The dopamine D1 receptor is a G-protein-coupled receptor which regulates (stimulates or inhibits) adenyl cyclase – the enzyme responsible for synthesis of cyclic AMP (cAMP). An increase in the concentration of cAMP in neurons enhances the sensation of pain. Conclusions. The genes (DRD1, COMT, OPRK1, HCN2) have a significant role in the pathogenesis of chronic pain in various diseases; they can also influence the perception of pain. Knowledge of these genes can contribute to the development of effective methods of combating pain.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2020, 27, 2; 274-278
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evaluation of circulating CD34+ stem cells in peripheral venous blood in patients with varying degrees of periodontal disease
    Autorzy:
    Aleksandrowicz, P.
    Kotuła, L.Z.
    Grabowska, K.
    Krakowiak, R.L.
    Kusa-Podkańska, M.
    Agier, J
    Gorący, A.
    Kądziołka, K.E.
    Kocki, J.
    Wysokińska-Miszczuk, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/28762730.pdf
    Data publikacji:
    2021
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2021, 28, 3; 516-520
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The effects of interior design on wellness – eye tracking analysis in determining emotional experience of architectural space. A survey on a group of volunteers from the Lublin region, Eastern Poland
    Autorzy:
    Tuszyńska-Bogucka, W.
    Kwiatkowski, B.
    Chmielewska, M.
    Dzieńkowski, M.
    Kocki, W.
    Pełka, J.
    Przesmycka, N.
    Bogucki, J.
    Galkowski, D.
    Powiązania:
    https://bibliotekanauki.pl/articles/2085475.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    supportive design
    healing environment
    emotional significance of space
    optimisation of treatment conditions
    eye tracking in medical research
    Opis:
    Introduction and objective. Using the concepts of Ulrich’s theory of supportive design and Malkin’s healing environment, an eye tracking experiment was designed in order to measure respondents’ reactions while looking at visualisations of various interiors, with the aim of verifying whether certain parameters of an interior are related to emotional reactions in terms of positive stimulation, and the sense of security and comfort. Materials and method. 12 boards were designed, incorporating standard features of an interior, i.e. (1) proportions, (2) lighting, (3) colour scheme of a room, as well as (4) the colours and spatial arrangement of furnishings. Respondents’ reactions were recorded with an eye tracker Tobii TX300 and supplemented by self-descriptions of emotional reactions. Results. The results showed that the varying spatial and colour arrangements presented in the interior visualisations provoked different emotional responses, confirmed by pupil reaction parameters, as measured by the eye tracking device. Conclusions. Architectural space can have a diverse emotional significance and impact on an individual’s emotional state. This is an important conclusion from the point of view of optimising and creating the so-called supportive and healing environment. The results have implications for the interpretation of the pupil diameter as an index of emotional reactions to different architectural space visualisations. Testing the eye tracker as a method helpful in diagnosing the emotional reactions to features of the interior is justified, and can provide an effective tool for early diagnosis of the impact of architectural space on the well-being of individuals. It can also be a good form of testing the emotional significance of architectural designs before they are implemented.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2020, 27, 1; 113-122
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Level of vitamin 25 (OH) D and B group vitamins and functional efficiency among the chronically ill elderly in domiciliary care - a pilot study
    Autorzy:
    Kocka, K.H.
    Ślusarska, B.J.
    Nowicki, G.J.
    Bartoszek, A.B.
    Rudnicka-Drożak, E.A.
    Panasiuk, L.
    Kocki, T.
    Powiązania:
    https://bibliotekanauki.pl/articles/2085032.pdf
    Data publikacji:
    2019
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    vitamin D3
    vitamin B12
    folic acid
    elderly
    long-term home care
    Opis:
    Introduction and objective. Deficits of vitamin resources constitute a significant public health problem, especially among the elderly population. The aim of the research was to determine the level of vitamin 25 (OH) D and vitamins from group B in the chronically ill elderly in domiciliary care, depending on functional capacity and coexisting diseases. Materials and method. The pilot study included 137 patients staying in long-term domiciliary care. Samples of the participants’ venous blood was obtained for laboratory tests. Centrifuged serum was used to determine the level of the following biochemical parameters: vitamin 25 (OH)D, B12, folic acid and total protein, albumin, triglycerides, total cholesterol and HDL cholesterol. Assessment of the functional status of patients was made by using the Barthel scale. Results. More than 3⁄4 of the patients with functional deficit (according to Barthel’s score 0–85 points) were deficient in vitamin 25 (OH)D, while folic acid values were below the reference values in more than half of the patients. Respondents with lower functional efficiency were characterised by a reduced average value of vitamin 25 (OH)D and folic acid. Conclusions. The studied group of the chronically ill elderly was characterised by a deficiency of vitamin D3 and folic acid. Subjects with a functional impairment deficit show a reduced mean value of vitamin 25 (OH)D and folic acid in the blood serum, compared to the group of patients with higher mobility.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2019, 26, 3; 489-495
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-13 z 13

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