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Wyszukujesz frazę "Kocik, J." wg kryterium: Autor


Wyświetlanie 1-12 z 12
Tytuł:
Research on prevention and treatment of hemorrhagic fevers
Autorzy:
Joniec, J.
Kolodziej, M.
Bartoszcze, M.
Kocik, J.
Knap, J.
Powiązania:
https://bibliotekanauki.pl/articles/52164.pdf
Data publikacji:
2012
Wydawca:
Instytut Medycyny Wsi
Opis:
Viral hemorrhagic fevers are severe zoonotic diseases caused by RNA-viruses classified into 4 families: Arenaviridae, Bunyaviridae, Filoviridae, and Flaviviridae. They are present on all continents except Antarctica, their person-to-person spread is easy, and there is a high risk of them being used as weapon by bioterrorists. So far, efforts to develop effective drugs against these viruses have failed, and typical therapy usually relies on symptomatic treatment. Search for substances that could effectively inhibit this type of infections is now a priority. The presented paper gives an overview of different approaches used in combating the viral hemorrhagic fevers. Researchers look for safe antiviral agents with appropriate properties among natural sources, such as various types of herbs plants, algae, or essential oils obtained from trees, as well as investigate the use of various synthetic substances. The aim is to broaden the pool of available antiviral drugs that could replace hitherto applied medicines such as ribavirin, which is not always sufficiently effective and may have side-effects. The scientists focus not only on combating the diseases, but also on their prevention. For this purpose, recombinant vaccines or various types of immunomodulators may serve as a useful tools. Results of the latest studies are promising and encourage further work which may eventually lead to the solution of the urgent problem of hemorrhagic fevers.
Źródło:
Annals of Agricultural and Environmental Medicine; 2012, 19, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Research on substances with activity against orthopoxviruses
Autorzy:
Kolodziej, M.
Joniec, J.
Bartoszcze, M.
Gryko, R.
Kocik, J.
Knap, J.
Powiązania:
https://bibliotekanauki.pl/articles/51870.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Opis:
Although smallpox was eradicated over 30 years ago, the disease remains a major threat. High mortality, high infectivity and low resistance of the contemporary population make the smallpox virus very attractive to terrorists. The possible presence of illegal stocks of the virus or risk of deliberate genetic modifications cause serious concerns among experts. Hence, it is reasonable to seek effective drugs that could be used in case of smallpox outbreak. This paper reviews studies on compounds with proven in vitro or in vivo antipoxviruses potential, which show various mechanisms of action. Nucleoside analogues, such as cidofovir, can inhibit virus replication. Cidofovir derivatives are developed to improve the bioavailability of the drug. Among the nucleoside analogues under current investigation are: ANO (adenozine N1-oxide) and its derivatives, N-methanocarbothymidine [(N)-MCT], or derivatitives of aciklovir, peninclovir and brivudin. Recently, ST-246 – which effectively inhibits infection by limiting release of progeny virions – has become an object of attention. It has been also been demonstrated that compounds such as: nigericin, aptamers and peptides may have antiviral potential. An interesting strategy to fight infections was presented in experiments aimed at defining the role of individual genes (E3L, K3L or C6L) in the pathogenesis, and looking for their potential blockers. Additionally, among substances considered to be effective in the treatment of smallpox cases, there are factors that can block viral inhibitors of the human complement system, epidermal growth factor inhibitors or immunomodulators. Further studies on compounds with activity against poxviruses are necessary in order to broaden the pool of available means that could be used in the case of a new outbreak of smallpox.
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Microarrays - new possibilities for detecting biological factors hazardous for humans and animals, and for use in environmental protection
Autorzy:
Mirski, T.
Bartoszcze, M.
Bielawska-Drozd, A.
Gryko, R.
Kocik, J.
Niemcewicz, M.
Chomiczewski, K.
Powiązania:
https://bibliotekanauki.pl/articles/51516.pdf
Data publikacji:
2016
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2016, 23, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bacillus anthracis infections – new possibilities of treatment
Autorzy:
Zakowska, D.
Bartoszcze, M.
Niemcewicz, M.
Bielawska-Drozd, A.
Knap, J.
Cieslik, P.
Chomiczewski, K.
Kocik, J.
Powiązania:
https://bibliotekanauki.pl/articles/51666.pdf
Data publikacji:
2015
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2015, 22, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
In vivo inhibitory effect of Aloe vera gel on the ability of mouse parental splenic lymphocytes to induce cutaneous angiogenesis in recipient F1 mice
Autorzy:
Skopinski, P.
Lewicki, S.
Balan, B.J.
Kocik, J.
Zdanowski, R.
Skopinska-Rozewska, E.
Siwicki, A.K.
Powiązania:
https://bibliotekanauki.pl/articles/30546.pdf
Data publikacji:
2014
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
Lymphocyte-induced angiogenesis test (LIA) is a model of local graft-versus-host (GVH) reaction, marker of the earliest events resulting from activation of donor lymphocytes after contact with host semi-allogeneic histocompatibility antigens. The effect of in vivo oral administration of Aloe vera gel for 21 days to maternal strain (Balb/c) donor mice on the ability of their splenic lymphocytes to induce cutaneous angiogenesis (LIA test) in F1 Balb/c x C3H recipients, was studied. Results: Neovascular reaction evaluated 72 hours after cells grafting was significantly lower in F1 mice grafted with lymphocytes collected from Aloe- fed donors, than in recipients of lymphocytes collected from respective controls. Conclusions: This observation opens the promise of safe and ethically acceptable possibility of use of Aloe vera gel in human donors in prevention of GVHD in recipients of bone marrow grafts.
Źródło:
Polish Journal of Veterinary Sciences; 2014, 17, 1
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Review of methods used for identification of biothreat agents in environmental protection and human health aspects
Autorzy:
Mirski, T.
Bartoszcze, M.
Bielawska-Drozd, A.
Cieslik, P.
Michalski, A.J.
Niemcewicz, M.
Kocik, J.
Chomiczewski, K.
Powiązania:
https://bibliotekanauki.pl/articles/51351.pdf
Data publikacji:
2014
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2014, 21, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Acute respiratory distress syndrome (ARDS) complicating influenza A/H1N1v infection – a clinical approach
Autorzy:
Witczak, A.
Prystupa, A.
Kurys-Denis, E.
Borys, M.
Czuczwar, M.
Niemcewicz, M.
Kocik, J.
Michalak, A.
Pietrzak, A.
Chodorowska, G.
Krupski, W.
Mosiewicz, J.
Tamasiewicz, K.
Powiązania:
https://bibliotekanauki.pl/articles/50695.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 4
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Microbiological analysis of bioaerosols collected from Hospital Emergency Departments and ambulances
Autorzy:
Bielawska-Drózd, A.
Cieślik, P.
Bohacz, J.
Kornillowicz-Kowalska, T.
Żakowska, D.
Bartoszcze, M.
Wlizło-Skowronek, B.
Winnicka, I.
Brytan, M.
Kubiak, L.
Skopińska-Różewska, E.
Kocik, J.
Powiązania:
https://bibliotekanauki.pl/articles/2081735.pdf
Data publikacji:
2018
Wydawca:
Instytut Medycyny Wsi
Tematy:
Button Sampler
bioaerosol
Hospital Emergency Departments
ambulances
bacteria
fungi
Opis:
Introduction and objective. The goal of the study was a microbiological, qualitative and quantitative analysis of bioaerosol at the workplace of medical personnel (Health Emergency Departments (HEDs), ambulances), and comparative administration offices with an expected neutral occupational exposure to biological agents measured with individual Button Sampler. Materials and method. Personal sampling was performed with Button Sampler instrument loaded with gelatine filters in 10 HEDs, in 9 ambulances and in 9 offices to assess the occupational biological agents’ exposure in air. Sampling was conducted from March until April 2016. Samples were quantitatively assessed for viable and total number of bacteria and fungi. Routine procedures for microbiological diagnostics were implemented. Data were analysed using Kruskal–Wallis and Mann-Whitney statistical tests with α=0.05. P value less than 0.05 were considered significant. Results. At the workplaces assessed, the concentrations of viable microorganisms in HEDs were 1.3 × 102 – 4.2 × 103 CFU/m3 for bacteria, 3.4 × 100 – 8.1 × 101 CFU/m3 for fungi; in ambulances 1.3 × 102 – 1.4 × 103 CFU/m3 (bacteria), 6.7 × 100 – 6.5 × 102 CFU/m3 (fungi) and in offices 4.2 × 101 – 5.0 × 103 CFU/m3 (bacteria), 0 – 7.9 × 102 CFU/m3 (fungi). In outdoor air, the number of microorganisms reached the level: 1.0 × 102 – 5.9 × 102 CFU/m3 for bacteria and 1.5 × 102 – 8.2 × 102 CFU/m3 for fungi. The predominant isolated bacteria were Gram-positive cocci. The prevalent fungi species belonged to the genus Aspergillus and Penicillium. Conclusions. The quantitative assessment of examined indoor air was similar to control outdoor air, and were relatively low. The level of microbiological contamination did not exceed 5 × 103 CFU/m3 which is recommended as an admissible level in public spaces in Poland.
Źródło:
Annals of Agricultural and Environmental Medicine; 2018, 25, 2; 274-279
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Severe Influenza Outbreak in Western Ukraine in 2009 – a molecular-epidemiological study
Autorzy:
Kocik, J.
Niemcewicz, M.
Johns, M.
Jerke, K.
Michalski, A.
Bielecka, A.
Lasocki, K.
Gawel, J.
Bielawska-Drozd, A.
Joniec, J.
Kolodziej, M.
Graniak, G.
Goniewicz, M.
Kubiak, L.
Powiązania:
https://bibliotekanauki.pl/articles/50555.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Opis:
Introduction: In the autumn of 2009 the authors participated in a humanitarian operation in Western Ukraine by undertaking an epidemiological investigation of an influenza-like-illness (ILI) in the L’viv Oblast region. Mobile biological survey teams took samples from civilian patients with severe acute respiratory distress syndrome, rapid transportation of the samples, and their molecular analysis in Poland to provide accurate results. Objective: The aim of the study was the molecular and epidemiological analysis of the biological samples collected. Material and Methods: Real-time reverse transcriptase polymerase chain reaction (real-time RT-PCR), multiplex PCR techniques, traditional Sanger Sequencing and classical viral culture methods were used. Results: Among the 124 influenza-like illness cases, ~50% (58) were positive for influenza A virus in WHO-CDC molecular assay, including subtyping. The specimens were further analyzed to confirm results and determine the genetic sequence. Phylogenetically, the nucleotide similarity of both the Ukraine specimens and reference A/California/7/2009 (pH1N1) was 99.2–99.3%. Oseltamivir resistance was not registered. HA1 region characterization showed an overall protein identity of 98.5–99.4%. Conclusions: An unexpected high contribution of influenza A was confirmed among ILI patients, as well as a very limited number of other detected viruses, indicate that the 2009 epidemic in western Ukraine was strongly related to novel influenza A/H1N1. The importance of swift sharing of information and reference laboratories networking in surveillance, as well as serving governments and international agencies in pursuing adequate actions, should be stressed.
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 3
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Acute respiratory distress syndrome (ARDS) in the course of influenza A/H1N1v infection – genetic aspects
Autorzy:
Niemcewicz, M.
Pajak, B.
Michalski, A.
Kocik, J.
Kolodziej, M.
Joniec, J.
Graniak, G.
Gawel, J.
Marciniak-Niemcewicz, A.
Kucharczyk, K.
Prystupa, A.
Witczak, A.
Lasocki, K.
Naylor, K.
Goniewicz, M.
Powiązania:
https://bibliotekanauki.pl/articles/49651.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 4
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pomiar pól prędkości mikroprzepływów za pomocą metody mikro-PIV
Measuring of the fluid flow velocity map with micro-PIV method
Autorzy:
Tański, M.
Kocik, M.
Barbucha, R.
Garasz, K.
Mizeraczyk, J.
Powiązania:
https://bibliotekanauki.pl/articles/267364.pdf
Data publikacji:
2013
Wydawca:
Politechnika Gdańska. Wydział Elektrotechniki i Automatyki
Tematy:
metoda PIV
mikroprzepływy
pole prędkości cieczy
PIV method
microflow
velocity maps
Opis:
W artykule przedstawiono metodę oraz wyniki pomiarów pól prędkości cieczy płynącej wewnątrz mikrokanału. W tym celu zastosowano metodę mikro-PIV (micro Particle Image Velocimetry). Metoda ta umożliwia pomiar prędkości pola przepływu cieczy na podstawie analizy toru ruchu cząstek posiewu płynących wraz z cieczą. Jako posiew zastosowano kulki żywicy melaminowej (o średnicy 10 μm) domieszkowane rodamina B. Badana objętość mikrokanału umieszczona została pod mikroskopem optycznym i oświetlona, dwoma krótkimi impulsami światła laserowego o długości fali 532 nm. Pod wpływem promieniowania laserowego rodamina B obecna w kulkach posiewu emitowała promieniowanie fluorescencyjne o długości fali 595 nm, które rejestrowano za pomocą zamontowanej do mikroskopu kamery CCD z zestawem filtrów optycznych. Analizując zmianę położenia kulek posiewu na dwóch kolejnych zdjęciach, odpowiadających dwóm kolejnym impulsom laserowym, wyznaczono przesuniecie cząstek powiewu w danym czasie. Na tej podstawie wnioskować mona o rozkładzie pola prędkości cieczy płynącej w mikrokanale.
In this paper a micro-PIV method for measuring a velocity map of the fluid flow in microchannels is presented. The micro- PIV method is based on the traditional Particle Image Velocimery (PIV) method and is applied for microscale measurements. In the micro-PIV method, velocity maps are obtained with the algorithm of displacement tracking of seed particles which are introduced into the fluid flow. Plastic balls filled with fluorescent rhodamine B of the diameter of 10 μm are used as seed particles. The experimental test stand consisted of an optical microscope with a CCD camera equipped with a set of optical filters, a twin Nd:YAG laser (wavelength = 532 nm), a Dantec timerbox unit and a computer with the software for data analysis. Seed particles are activated with laser radiation and emit the fluorescent light of = 592 nm which is captured with the CCD camera. The trace of the seed particles is calculated using computer algorithms. Fluid velocity maps are calculated on the base of the calculated trace of the seed particles.
Źródło:
Zeszyty Naukowe Wydziału Elektrotechniki i Automatyki Politechniki Gdańskiej; 2013, 34; 71-73
1425-5766
2353-1290
Pojawia się w:
Zeszyty Naukowe Wydziału Elektrotechniki i Automatyki Politechniki Gdańskiej
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-12 z 12

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