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    Wyświetlanie 1-14 z 14
    Tytuł:
    Assessment of the presence of pancreatic intraepithelial neoplasia in various diseases of this organ
    Autorzy:
    Zińczuk, J.
    Zaręba, K.
    Konarzewska-Duchnowska, E.
    Guzińska-Ustymowicz, K.
    Kędra, B.
    Kemona, A.
    Pryczynicz, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918553.pdf
    Data publikacji:
    2017-11-12
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    pancreatic intraepithelial neoplasia
    PanIN
    pancreatic ductal adenocarcinoma
    pancreatic cancer
    chronic pancreatitis
    Opis:
    Purpose: Pancreatic intraepithelial neoplasia (PanIN) is one of the most commonly occurring precancerous lesion in pancreas which leads to development of pancreatic ductal adenocarcinoma (PDAC). We assessed the presence and grade of pancreatic intraepithelial neoplasia in the course of various diseases of the pancreas and its correlations with chosen clinicopathological parameters. null Results: A total of 276 foci of PanIN were identified in 94 patients. The most common lesions were PanIN 1a and PanIN 1b which together constituted 68.2 % of all lesions, whereas the PanIN 2 was present in 21.7% and PanIN 3 in 10.1% of patients. No statistical differences were observed in gender tendency for the development of PanINs. There was correlation between age of patients and degree of PanIN (p=0.034). There is no statistical difference in PanIN frequency among patients with pancreatic ductal adenocarcinomas, neuroendocrine tumors, chronic pancreatitis and pancreatic cysts (p=0.592). Conclusions: Our study showed that important factor in development of pancreatic intraepithelial neoplasia is age and the presence of PanIN in nonneoplastic diseases in older people should be included to the group with increased risk of cancer development.
    Źródło:
    Progress in Health Sciences; 2017, 7(2); 43-49
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Poziom metioniny-14C w narządach szczura w ostrym zatruciu lindanem
    UROWEN’ METIONINA 14-C W ORGANAKH KRYSY W OSTROM OTRAWLENII LINDANOM
    THE LEVEL OF 14C METHIONINE IN RAT ORGANS IN ACUTE POISONING WITH LINDAN
    Autorzy:
    Sulik, M.
    Nowak, H.F.
    Kemona, A.
    Deregowski, K.
    Stefanska-Sulik, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/872811.pdf
    Data publikacji:
    1988
    Wydawca:
    Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
    Tematy:
    metionina
    zatrucia
    lindan
    toksykologia
    pomiary
    radiometria
    aktywnosc promieniotworcza
    Źródło:
    Roczniki Państwowego Zakładu Higieny; 1988, 39, 4
    0035-7715
    Pojawia się w:
    Roczniki Państwowego Zakładu Higieny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The expression of apoptosis-related proteins in patients with ulcerative colitis
    Autorzy:
    Niewiarowska, K.
    Lebelt, A.
    Gryko, M.
    Pryczynicz, A.
    Famulski, W.
    Czyżewska, J.
    Kemona, A.
    Piekarska-Dymicka, V.
    Jagodzińska, D.
    Guzińska-Ustymowicz, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/1916338.pdf
    Data publikacji:
    2014
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Ulcerative colitis
    Bcl-xl
    Bax
    Bid
    Bcl-2
    Opis:
    Purpose: Recent literature data indicate a key role of apoptosis in the pathogenesis of inflammatory bowel disease. The aim of the study was to evaluate the expression of Bax, Bid, Bcl-2 and Bcl-xl in non-dysplastic and dysplastic epithelium in inflamated mucosa of patients with ulcerative colitis. Methods: The study consists of 18 patients with diagnosed ulcerative colitis. The expression of proteins was determined immunohistochemically. Results: Lack of Bax expression in normal epithelium of the inflamed intestinal mucosa (94.4%) and a weak expression of this protein were found in dysplastic glandular cells (67%). The Bax expression of dysplastic epithelium correlates with reduced severity of chronic inflammation (p<0.005). Bid expression in non-dysplastic glands was found in 67% of cases vs. 16% in dysplastic epithelium that was associated with the occurrence of epithelial erosions or ulcers (p<0.05). Moderate cytoplasmic expression of Bcl-xl was noted in 27.7% of patients in normal epithelium and in 66.1% within dysplastic lesions. Bcl-xl expression in dysplastic glandular cells correlated with the presence of neutrophils in the lamina propria (p <0.05). Conclusions: The immunohistochemical expressions of Bax, Bcl-2 and Bcl-xl increase and Bid protein expression decreases in dysplastic glandular tubes as compared to non-dysplastic intestinal epithelium in inflamed mucosa, which may suggest an imbalance of controlled cell death in ulcerative colitis.
    Źródło:
    Progress in Health Sciences; 2014, 4, 1; 75-82
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The influence of Helicobacter pylori eradication therapy on the presence of H. pylori antigens in dental plaque and saliva
    Autorzy:
    Namiot, D.B.
    Leszczyńska, K.
    Namiot, A.
    Kemona, A.
    Bucki, R.
    Chilewicz, M.
    Namiot, Z.
    Powiązania:
    https://bibliotekanauki.pl/articles/1917816.pdf
    Data publikacji:
    2016
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Helicobacter pylori treatment
    immunoassay
    gastric mucosa
    oral cavity
    Opis:
    Purpose: The aim of this study was to evaluate the presence of H. pylori antigens in the oral cavity (dental plaque and saliva) of patients undergoing systemic eradication therapy. Materials and methods: The study was conducted in 49 subjects with H. pylori stomach infection. H. pylori antigens in dental plaque and saliva were evaluated with immunological method. Results: In subjects with initial H. pylori oral infection, the presence of H. pylori antigens in the oral cavity 6 weeks after successful or unsuccessful H. pylori eradication therapy in the stomach was 47.0% and 50.0%, respectively. In subjects without initial oral infection with H. pylori, the presence of H. pylori antigens in the oral cavity 6 weeks after successful and unsuccessful eradication therapy in the stomach was 30.0% and 20.0%, respectively. Conclusions: The immunological method detecting H. pylori antigens in the dental plaque and saliva cannot be recommended to evaluate the efficacy of H. pylori eradication in the oral cavity.
    Źródło:
    Progress in Health Sciences; 2016, 6(1); 19-24
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Application of Helicobacter pylori antigen test to evaluate gastric mucosa specimens
    Autorzy:
    Namiot, A.
    Leszczyńska, K.
    Namiot, D.B.
    Chilewicz, M.
    Bucki, R.
    Kemona, A
    Namiot, Z.
    Powiązania:
    https://bibliotekanauki.pl/articles/1916576.pdf
    Data publikacji:
    2014
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Helicobacter pylori antigens
    immunoassay
    gastric mucosa
    Opis:
    Purpose: To investigate, whether the test documenting the presence of Helicobacter pylori (H. pylori) antigens in the gastric mucosa may be used as diagnostic test. Materials and methods: Mucosal specimens taken from eighty-three patients during gastroscopic examination were subjected to rapid urease test (CLO test), histology, and H. pylori culture. The same biopsy specimens that had been evaluated in the CLO test or collected into the transport medium for bacterial culture were used to detect H. pylori antigens. An amplified immunoassay for the detection of H. pylori antigens in stool was used for gastric mucosa specimens. The sensitivity and specificity of the H. pylori antigen test were evaluated in relation to the results of each verifying test (CLO test, histology, culture) separately and to all 3 tests analysed together. Results: The sensitivity and specificity of the H. pylori antigen test in relation to the CLO test, histological examination, and H. pylori culture were 85.4% and 90.5%, 76.1% and 83.4%, and 90.7% and 90.0% for specimens taken for the CLO test and 90.0% and 82.0%, 78.0% and 81.0%, and 93.0% and 88.0% for specimens taken for bacterial culture, respectively. The sensitivity and specificity of the antigen test in relation to all 3 verifying tests analysed together were 91.3% and 97.3% for specimens taken for the CLO test, and 91.7% and 97.1% for specimens taken for bacterial culture, respectively. Conclusions: H. pylori antigen test in gastric mucosa specimens may be a sufficiently reliable source of information about stomach infection.
    Źródło:
    Progress in Health Sciences; 2014, 4, 2; 52-57
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Helicobacter pylori infection in North-East Poland between 1996 and 2011 on the base of histological examination
    Autorzy:
    Namiot, A.
    Chilewicz, M.
    Kurylonek, A. J.
    Skwarski, L.
    Romatowski, J
    Killar, G.
    Jaroszewicz, W.
    Kralisz, M.
    Chętnik, A.
    Bucki, R.
    Kemona, A.
    Namiot, Z.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918587.pdf
    Data publikacji:
    2018-06-18
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Helicobacter pylori
    histology
    gastric mucosa
    Opis:
    Purpose: The aim of the study was to conduct a 15- year (1996-2011) observations on the frequency of Helicobacter pylori stomach infection in patients having performed gastroscopy in the Endoscopy Unit District Hospital of Białystok, Poland Materials and methods: Out of the 27421 patients who underwent a gastroscopy in 1996-1997, 2000- 2001, 2005-2006, and 2010-2011 years were selected 4216 subjects who had performed histological examination of gastric mucosal specimens for H. pylori infection. The mucosal specimens after placed in buffered formalin, were subjected to standard histological procedure, and stained with hematoxylineosin and Giemsa. Results: Stomach infection with H. pylori was 73.36% (1996-1997), 48.60% (2000-2001), 33.61% (2005-2006) and 32.30% (2010-2011); only between the last two 2-year intervals the difference was not significant. Conclusions: The results of current study indicate on steadily declining stomach infection with H. pylori. Keywords: Helicobacter pylori, histology, gastric mucosa
    Źródło:
    Progress in Health Sciences; 2018, 8(1); 22-26
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The clinical importance of Helicobacter pylori antigens detected in the dental plaque and feces
    Autorzy:
    Namiot, A.
    Leszczyńska, K.
    Namiot, D.
    Bucki, R.
    Kemona, A.
    Chilewicz, M.
    Namiot, Z.
    Powiązania:
    https://bibliotekanauki.pl/articles/1917520.pdf
    Data publikacji:
    2015
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Helicobacter pylori antigens
    Immunoassay
    Dental Plaque
    Feces
    Opis:
    Purpose:It is expected that H. pylori residing outside the stomach influences the results of the stool test. The aim of the study was to investigate the occurrence of H. pylori antigens in dental plaque and feces of the patients with H. pylori infected and non-infected stomachs.Materials and methods: The study was conducted in 188 dentate patients, 107 with H. pylori infected and 81 non-infected stomachs. Stomach infection with H. pylori was evaluated with CLO test, histology and culture. The stomach was classified as infected if at least two of three tests (CLO test, culture, histology) were positive and as non-infected if all three tests were negative. Dental plaque was taken only from the natural teeth. On the day of the gastroscopic examination or on the next two days a stool sample was collected for H. pylori antigens testing. H. pylori antigens in dental plaque and feces were determined by immunological method.Results:In 60.8% of subjects with an infected stomach, H. pylori antigens were present both in the dental plaque and feces, in 37.4% in feces only, in 0.9% only in the dental plaque, and in 0.9% neither in the dental plaque nor feces. In 46.9% of subjects with a non-infected stomach, H. pylori antigens were found neither in the dental plaque nor feces, in 24.7% both in the dental plaque and feces, in 23.5% only in the dental plaque, and in 4,9% only in feces.Conclusions: There is a weak association between the occurrence of H. pylori antigens in feces and the dental plaque, and also between the occurrence of the antigens in the dental plaque and stomach infection.
    Źródło:
    Progress in Health Sciences; 2015, 5, 2; 24-29
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Vitamin C does not improve the efficacy of Helicobacter pylori eradication in smokers
    Autorzy:
    Namiot, A.
    Namiot, D.B.
    Bucki, R.
    Kemona, A.
    Kurylonek, A.J.
    Namiot, Z.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918926.pdf
    Data publikacji:
    2020-06-10
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Helicobacter pylori
    treatment
    vitamin C
    Opis:
    Purpose: To evaluate the hypothesis that vitamin C improves the efficacy of Helicobacter pylori eradication in smokers when combined with pantoprazole, amoxicillin, and clarithromycin. Materials and methods: The study completed 90 subjects of 98 enrolled, 58 smokers 32 nonsmokers. Helicobacter pylori status was determined by two methods, CLO test, and histology. Vitamin C (500 mg) was administered three times daily. The patients were considered as cured of H. pylori if the CLO test result and histology were negative 4 weeks after completion of eradication therapy. Results: Smokers had lower effectiveness of eradication therapy than non-smokers and the administration of vitamin C had not affected the outcome of eradication therapy. Conclusions: Vitamin C (500 mg tid) does not improve the eradication therapy when pantoprazole, amoxicillin, and clarithromycin were used.
    Źródło:
    Progress in Health Sciences; 2020, 10(1); 77-81
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ocena stezenia IL-5 i IL-6 w echinokokozie
    Autorzy:
    Matowicka-Karna, J.
    Kemona, H.
    Panasiuk, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/839644.pdf
    Data publikacji:
    2004
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    choroby pasozytnicze
    parazytologia lekarska
    stezenie
    interleukina 5
    interleukina 6
    immunoglobulina E
    Echinococcus granulosus
    bablowica
    pasozyty czlowieka
    Źródło:
    Annals of Parasitology; 2004, 50, 3; 435-438
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ocena stężenia IL-5 i IL-6 w echinokokozie
    The evaluation of concentrations IL-5 and IL-6 in echinococcosis
    Autorzy:
    Matowicka-Karna, J.
    Kemona, H.
    Panasiuk, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/2147393.pdf
    Data publikacji:
    2004
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    choroby pasozytnicze
    parazytologia lekarska
    stezenie
    interleukina 5
    interleukina 6
    immunoglobulina E
    Echinococcus granulosus
    bablowica
    pasozyty czlowieka
    Opis:
    The immune system, its cellular and humoral response, is engaged by the host organism to fight against parasitic invasions. The group examined consisted of 24 patients (19 women and 5 men) aged 26-69 years infected with Echinococcus granulosus. The diagnosis was established basing on serological examination. Blood for analysis was collected before antiparasitic treatment. Control group consisted of 40 healthy people (22 women and 18 men) aged 20-45 years. The concentration of IgE were assayed using a set of VIDAS (the ELFA method). The concentration of IL-5, IL-6 were assayed using a set of Quantikine human (R&D Systems). The study demonstrated that in echinococcosis the concentrations of IgE, IL-5 and IL-6 contents in blood serum was higher 10-, 2- and 3-times, respectively than in healthy controls.
    Źródło:
    Wiadomości Parazytologiczne; 2004, 50, 3; 435-438
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ocena stezenia IL-5 i IL-6 w toksoplazmozie
    Autorzy:
    Matowicka-Karna, J.
    Kemona, H.
    Panasiuk, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/837900.pdf
    Data publikacji:
    2004
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    toksoplazmoza
    odpowiedz immunologiczna
    choroby pasozytnicze
    parazytologia lekarska
    stezenie
    interleukina 5
    interleukina 6
    immunoglobulina E
    inwazja pasozytnicza
    Toxoplasma gondii
    Źródło:
    Annals of Parasitology; 2004, 50, 3; 417-423
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ocena stężenia IL-5 i IL-6 w toksoplazmozie
    The evaluation of concentrations il-5 and il-6 in toxoplasmosis
    Autorzy:
    Matowicka-Karna, J.
    Kemona, H.
    Panasiuk, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/2147386.pdf
    Data publikacji:
    2004
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    toksoplazmoza
    odpowiedz immunologiczna
    choroby pasozytnicze
    parazytologia lekarska
    stezenie
    interleukina 5
    interleukina 6
    immunoglobulina E
    inwazja pasozytnicza
    Toxoplasma gondii
    Opis:
    The immune system, its cellular and humoral response, is engaged by the host organism to fight against parasitic invasions. The group examined consisted of 38 women aged 19-39 years infected with Toxoplasma gondii. The diagnosis was established basing on serologic examination. Blood for analysis was collected before antiparasitic treatment. Control group consisted of 40 healthy women aged 18-46 years. The concentrations of IgM, IgG and IgE were assayed using a set of VIDAS (bioMerieux) according to the ELFA method. The concentrations of IL-5, IL-6 were assayed using a set of Quantikine human (R&D Systems) according to the immunoenzymatic methods with labeled antibodies. The present study revealed that in toxoplasmosis the concentration of IgE, IL-5 and IL-6 contents in blood serum was 2-times higher, than in healthy controls.
    Źródło:
    Wiadomości Parazytologiczne; 2004, 50, 3; 417-423
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Microorganisms potentially useful in the management of polyurethane foam waste
    Autorzy:
    Kemona, A.
    Piotrowska, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/101430.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Stowarzyszenie Infrastruktura i Ekologia Terenów Wiejskich PAN
    Tematy:
    polyurethane foam
    biodegradation
    PUR
    Opis:
    Polyurethane foams due to their easily regulated domain structure are group of polymers with highly variable properties. They are widely used to provide comfort in many areas of daily life. Because of toxic products polyurethane foam waste cannot be disposed by means of thermal degradation, they also show a high resistance to chemical and physical factors. Those properties combined with their low apparent density and widespread use (about 18 million tons per year) lead to a significant volume of waste that is stored in landfills. In Poland, more than 60% of those landfills, certified as well as illegal, are located in rural areas. The aim of this study was to determine the enzymatic abilities of microorganisms isolated from foam waste, which can potentially decompose polyurethane (ureases, esterases, proteases, and laccases), and to determine their ability to grow on a medium containing polyurethane foam as the only carbon source. Most of the tested strains produced ureases while the least produced were laccases and proteases. Four of the tested strains: Epicoccum nigrum, Aspergillusniger, Staphylococcusxylosus and Rhodococcus spp. showed significant growth on the medium with polyurethane foam as sole carbon source.
    Źródło:
    Infrastruktura i Ekologia Terenów Wiejskich; 2016, IV/2; 1297-1308
    1732-5587
    Pojawia się w:
    Infrastruktura i Ekologia Terenów Wiejskich
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Rozmieszczenie kwasu 2,4-dichlorofenoksyoctowego-14C (2,4-D) w tkankach szczura w ostrym zatruciu
    Distribution and elimination of 2,4-dichlorophenoxyacetic-14C (2,4-D) acid in acute poisoning in rats
    Raspredelenie i udalenie 2,4-dvukhlorofenoksiuksusiojj-14S kisloty (2,4-D) v ostrom otravlenii krys
    Autorzy:
    Deregowski, K.
    Sulik, M.
    Kemona, A.
    Stefanska-Sulik, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/876760.pdf
    Data publikacji:
    1990
    Wydawca:
    Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
    Tematy:
    szczury Wistar
    zatrucia ostre
    badania radiometryczne
    wchlanianie
    herbicydy
    zatrucia pokarmowe
    wyniki badan
    zmiany morfologiczne
    zaburzenia funkcjonalne
    Źródło:
    Roczniki Państwowego Zakładu Higieny; 1990, 41, 1-2
    0035-7715
    Pojawia się w:
    Roczniki Państwowego Zakładu Higieny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-14 z 14

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