- Tytuł:
- Inflammatory response to acute exposure to welding fumes during the working day
- Autorzy:
-
Järvelä, Merja
Kauppi, Paula
Tuomi, Timo
Luukkonen, Ritva
Lindholm, Harri
Nieminen, Riina
Moilanen, Eeva
Hannu, Timo - Powiązania:
- https://bibliotekanauki.pl/articles/2179774.pdf
- Data publikacji:
- 2013-04-01
- Wydawca:
- Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
- Tematy:
-
cytokines
E-selectin
Exhaled Nitric Oxide (NO)
heart rate variability (HRV)
interleukin-1β
welding - Opis:
- Objectives: To investigate cardiorespiratory and inflammatory responses in male workers following exposure to welding fumes and airborne particles in actual workplace conditions. Materials and Methods: We measured blood leukocytes and their differential counts, platelet count, hemoglobin, sensitive C-reactive protein, fibrinogen, E-selectin, IL-(interleukin)1β, IL-6, IL-8, tumor necrosis factor alpha (TNF-α) and endothelin-1 in blood samples of twenty workers before and after their working day. We also studied peak expiratory flow (PEF), forced expiratory volume in one second (FEV₁), and exhaled nitric oxide (NO). We assessed heart rate variability (HRV) by obtaining 24-hour ambulatory electrocardiograms. Results: The total blood leukocytes and neutrophils increased after the work shift, whereas IL-1β and E-selectin decreased significantly. There were no tatistically significant changes in exhaled NO, FEV₁, PEF or HRV. Conclusion: Occupational exposure to welding fumes and particles caused a slight, acute inflammatory effect estimated based on the increased values of leukocytes and neutrophils in blood and a decrease in the interleukin 1β and E-selectin values, but no changes in the pulmonary function (exhaled NO, FEV₁, PEF) or HRV during the working day were observed.
- Źródło:
-
International Journal of Occupational Medicine and Environmental Health; 2013, 26, 2; 220-229
1232-1087
1896-494X - Pojawia się w:
- International Journal of Occupational Medicine and Environmental Health
- Dostawca treści:
- Biblioteka Nauki
Artykuł