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    Wyświetlanie 1-2 z 2
    Tytuł:
    Usage of pregabalin in the treatment of pain associated with chronic pancreatitis – a clinically oriented narrative review
    Autorzy:
    Gałązka, Jakub K.
    Skrzydło-Radomańska, Barbara
    Kasztelan-Szczerbińska, Beata
    Cichoż-Lach, Halina
    Powiązania:
    https://bibliotekanauki.pl/articles/24987725.pdf
    Data publikacji:
    2023-06-22
    Wydawca:
    Gdański Uniwersytet Medyczny
    Tematy:
    chronic pancreatitis
    pain
    pregabalin
    Opis:
    Abdominal pain is one of the main symptoms of pancreatic diseases, including chronic pancreatitis (CP). Once the disease is in remission, pain management is a key element of treatment. Co-analgesics may also be used at any stage of analgesia, among which antiepileptic drugs such as pregabalin. The first data on the beneficial effect of pregabalin on pain in the course of CP was published in a clinical trial in 2011, and it has been known since 2015 that the analgesic effect of pregabalin on CP has a different mechanism of action than conventional analgesics. Currently, research is focused on combining pregabalin with antioxidants and on methods to predict the patient's response to pregabalin administration. Based on current research, pregabalin appears to be a very useful agent for the pharmacologic treatment of pain in the setting of CP.
    Źródło:
    European Journal of Translational and Clinical Medicine; 2023, 6, 2; 91-94
    2657-3148
    2657-3156
    Pojawia się w:
    European Journal of Translational and Clinical Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Results of screening in Lublin Province, Poland, for colorectal cancer and neoplastic polyps - the role of environmental factors
    Autorzy:
    Cichoż-Lach, Halina
    Szumiło, Justyna
    Celiński, Krzysztof
    Kasztelan-Szczerbińska, Beata
    Szczerbiński, Mariusz
    Swatek, Jarosław
    Wronecki, Lech
    Wargocki, Janusz
    Słomka, Maria
    Powiązania:
    https://bibliotekanauki.pl/articles/989962.pdf
    Data publikacji:
    2017
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    neoplastic polyps of colon
    advanced adenoma of colon
    colorectal cancer screening
    Opis:
    Introduction and objective. Screening colonoscopy is a recommended tool, and the most sensitive and cost-effective method for reducing the incidence of colorectal cancer (CRC). Objective. The purpose of the study was to present the results of a 5-year screening for early detection of CRC carried out among the population of the central-eastern regions of Poland, primarily in Lublin Province. Materials and method. Screening colonoscopy was conducted in a group of 1,009 patients – 636 women and 373 men, aged 40–65 years. Results. Neoplastic polyps were found in 275 patients, advanced adenomas in 49 patients and adenocarcinoma in 13. 70.55% of neoplastic polyps was located in the distal colon, 18.9% in the proximal part and 10.55% in both regions, advanced adenomas in 79.59%, 8.16% and 12.25%, respectively. Adenocarcinoma was located in the proximal colon in 2 cases and in the distal region in 11 cases. Neoplastic polyps and advanced adenomas occurred significantly more frequently in smokers than in non-smokers. Neoplastic polyps were found statistically more frequent in males than in females, among the overweight and obese patients, than in subjects with normal BMI, and more frequently in the group of urban, compared to rural patients. However, the frequency of advanced adenomas and CRC was not statistically different in those groups. The incidence of CRC was statistically more frequent in males than in females. Smoking and male gender were significant risk factors for developing neoplastic polyps. Male gender seemed to predispose to CRC. Obesity was found to favour advanced adenomas. Conclusions. The results of screening found neoplastic polyps in every third person (mean) who did not have any symptoms suggestive of colon pathology. Advanced adenomas were found in 5% of the examined and CRC was detected in 1.29% of participants. Smoking, male gender and overweight were significant risk factors for developing neoplastic polyps. No correlation was found between gender and the location of neoplastic polyps and advanced adenomas in the colon.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2017, 24, 1
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-2 z 2

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