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    Wyświetlanie 1-9 z 9
    Tytuł:
    Malaria: the forgotten threat. A case study of patients hospitalized in the Department of Infectious Diseases and Hepatology at the Pomeranian Medical University Szczecin
    Malaria - zapomniane zagrożenie. Analiza przypadków malarii u osób leczonych w Klinice Chorób Zakaźnych i Hepatologii Pomorskiego Uniwersytetu Medycznego w Szczecinie
    Autorzy:
    Laurans, L.
    Niscigorska-Olsen, J.
    Socha, L.
    Urbanska, A.
    Jurczyk, K.
    Karpinska, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/44769.pdf
    Data publikacji:
    2012
    Wydawca:
    Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
    Opis:
    Malaria remains a major health issue In the world, while in Poland no cases of the indigenous disease have been observed since 60-ties of the last century, but the number of cases imported from the epidemic areas is increasing. The aim of work was to analyse the epidemiology of malaria diagnosed and treated in the Department of Infectious Diseases and Hepatology, Pomeranian Medical University, Szczecin, Poland from 1.02.2010 until 31.01.2011. In total 11 cases were found, all diagnoses based on the thick and thin blood smear microscopy, alongside to the standard laboratory analyses.All clinical data presented are based on the case history. Results: Majoriry of cases reported travel to Sub-Saharan Africa (45%) or Indian subcontinent (27%). The travel was usually for recreational purposes, with significant proportion (45%) of patient not taking the malaria prophylaxis. Clinical course of infections was largely mild, with dominance of Pl. Falciparum parasitaemia. Fever was the most common clinical symptom (90%), while in the routine laboratory test no significant abnormalities, suggesting the disease, were found. Conclusions: malaria should be suspected in every case of the returning traveler with fever, especially if the travel was to the endemic area. The exclusion of the disease cannot be based on routine laboratory tests or quick immunoassays – thick and thin blood smear microscopy must be performed.
    Malaria ciągle jest głównym problemem zdrowotnym świata, natomiast w Polsce od lat 60. ubiegłego wieku nie stwierdzono rodzimych przypadków malarii. Zwraca jednak uwagę ostatnio rosnąca liczba pacjentów z malarią powracających ze stref epidemicznych. Celem pracy była analiza epidemiologiczna wszystkich przypadków potwierdzonej malarii leczonych w Katedrze i Klinice Chorób Zakaźnych PUM w Szczecinie w okresie między 1.02.2010 a 31.01.2011 r. Do analizy zakwalifikowano 11 przypadków malarii hospitalizowanych w Oddziale Chorób Zakaźnych i Hepatologii. U wszystkich rozpoznanie tej parazytozy oparto na badaniu grubej kropli i cienkiego rozmazu, dodatkowo u wszystkich wykonano rutynową diagnostykę laboratoryjną. Dodatkowe informacje uzyskano na podstawie poszerzonego wywiadu lekarskiego. Wyniki: najczęściej pacjenci z malarią powracali z Afryki Subsaharyjskiej (45%) bądź z Półwyspu Indyjskiego (27%). Większość osób wyjeżdżała w celach turystycznych, a znamienna większość nie przyjmowała chemoprofilaktyki przeciwmalarycznej. Wśród analizowanych pacjentów, poza jednym przypadkiem, dominowały łagodne postaci malarii, głównie gatunek Pl. falciparum. Prawie u wszystkich osób występowała gorączka (90%), natomiast w rutynowych badaniach dodatkowych nie wykazano odchyleń uznanych za wykładniki tej choroby. Wnioski: malarię należy podejrzewać u każdego chorego powracającego z rejonu epidemicznego, zwłaszcza, jeżeli występuje gorączka. Nie można wykluczyć tej choroby na badaniach rutynowych czy szybkich testach immunoenzymatycznych, a jedynie na podstawie grubej kropli i cienkiego rozmazu.
    Źródło:
    Acta Scientiarum Polonorum. Zootechnica; 2012, 11, 1
    1644-0714
    Pojawia się w:
    Acta Scientiarum Polonorum. Zootechnica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Concentration of magnesium in the serum and the ability status of patients with relapsing-remitting multiple sclerosis
    Autorzy:
    Karpińska, E.
    Socha, K.
    Soroczyńska, J.
    Kochanowicz, J.
    Jakoniuk, M.
    Mariak, Z.
    Borawska, M. H.
    Powiązania:
    https://bibliotekanauki.pl/articles/961427.pdf
    Data publikacji:
    2017
    Wydawca:
    Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
    Opis:
    Multiple sclerosis (MS) is the most common autoimmune disease affecting the central nervous system, characterized by the presence of scattered foci of demyelination in the brain and spinal cord. Magnesium (Mg) has a significant influence on the nervous system and the immune system. The aim of this study was to evaluate the influence of the concentration of Mg in the serum on the ability status of patients with MS. The study group consisted of 101 adults with diagnosed relapsing remitting MS. All participants were investigated on the Expanded Disability Status Scale. The control group included 41 people. The concentration of Mg in the serum was determined by the flame atomic absorption spectrometry method. The patients completed a survey and a 24-hour dietary interview. In patients with MS, the percentage of respondents with normal magnesium content was significantly lower than in the control group (p < 0.05). The study proved that patients with normal Mg serum concentration levels were in better clinical condition, particularly with respect to the function of the pyramidal tract (p = 0.007) and sphincters (p = 0.002), than patients with inadequate levels of Mg in the serum. External factors such as gender, smoking, immunomodulating medications or dietary supplements of Mg were found to have no effect on the concentration of Mg in the serum of MS patients. The results of our study suggest that an abnormal concentration of Mg in the serum of MS patients should be recognized and corrected, as this may improve the health status of people with MS.
    Źródło:
    Journal of Elementology; 2017, 22, 2
    1644-2296
    Pojawia się w:
    Journal of Elementology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Concentration of magnesium in the serum and the ability status of patients with relapsing-remitting multiple sclerosis
    Autorzy:
    Karpińska, E.
    Socha, K.
    Sroczyńska, J.
    Kochanowicz, J.
    Jakoniuk, M.
    Mariak, Z.
    Borawska, M.H.
    Powiązania:
    https://bibliotekanauki.pl/articles/1189829.pdf
    Data publikacji:
    2017
    Wydawca:
    Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
    Tematy:
    multiple sclerosis
    magnesium
    EDSS
    environmental factors
    diet
    Opis:
    Multiple sclerosis (MS) is the most common autoimmune disease affecting the central nervous system, characterized by the presence of scattered foci of demyelination in the brain and spinal cord. Magnesium (Mg) has a significant influence on the nervous system and the immune system. The aim of this study was to evaluate the influence of the concentration of Mg in the serum on the ability status of patients with MS. The study group consisted of 101 adults with diagnosed relapsing remitting MS. All participants were investigated on the Expanded Disability Status Scale. The control group included 41 people. The concentration of Mg in the serum was determined by the flame atomic absorption spectrometry method. The patients completed a survey and a 24-hour dietary interview. In patients with MS, the percentage of respondents with normal magnesium content was significantly lower than in the control group (p < 0.05). The study proved that patients with normal Mg serum concentration levels were in better clinical condition, particularly with respect to the function of the pyramidal tract (p = 0.007) and sphincters (p = 0.002), than patients with inadequate levels of Mg in the serum. External factors such as gender, smoking, immunomodulating medications or dietary supplements of Mg were found to have no effect on the concentration of Mg in the serum of MS patients. The results of our study suggest that an abnormal concentration of Mg in the serum of MS patients should be recognized and corrected, as this may improve the health status of people with MS.
    Źródło:
    Journal of Elementology; 2017, 22, 2
    1644-2296
    Pojawia się w:
    Journal of Elementology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Outbreak of ranavirus infection in sheatfish, Silurus glanis (L.), in Poland
    Autorzy:
    Borzym, E.
    Karpinska, T.A.
    Reichert, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/31663.pdf
    Data publikacji:
    2015
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    Ranavirus was detected in adult sheatfish, with clinical signs, on a Polish fish farm in February. Farm isolates induced a strong cytopathic effect in vitro and were identified by electron microscopy and PCR amplification of the ranavirus specific gene fragment. Restriction analysis with the Acc I enzyme showed that isolated ranaviruses were different from the epizootic heamatopoietic necrosis virus (EHNV). We sequenced a fragment of the major capsid protein (MCP) gene and found that isolates were similar to other strains of ranaviruses, available in GenBank.
    Źródło:
    Polish Journal of Veterinary Sciences; 2015, 18, 3
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Neuroprotective activity of 2-amino-1,3,4-thiadiazole derivative 4BrABT – an in vitro study
    Autorzy:
    Juszczak, M.
    Walczak, K.
    Langner, E.
    Karpinska, M.
    Matysiak, J.
    Rzeski, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/49999.pdf
    Data publikacji:
    2013
    Wydawca:
    Instytut Medycyny Wsi
    Opis:
    4BrABT (2-(4-Bromophenylamino)-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazole) is a compound known for its interesting in vitro anticancer profile. 4BrABT inhibited proliferation and motility of several cancer cell lines in concentrations which were not toxic to normal cells. A major problem associated with cancer chemotherapy, but also caused by environmental factors such as pesticides, is neurotoxicity. Therefore, the aim of the presented study was an in vitro evaluation of the neuroprotective activity of this compound. 4BrABT activity (1–100 μM) was tested in cultures of mouse neurons, rat astrocytes and rat oligodendrocytes. A possible protective action of the compound in different neurodegenerative models, as serum deprivation (SD), excitotoxicity (presence of 500 μM glutamate in culture medium), as well as cisplatin toxicity (astroglia – 50 μM and oligodendroglia – 100 μM) was investigated. Cell viability in the tested cultures was assessed with the use of LDH and MTT methods. Moreover, 4BrABT ability to prevent the cisplatin-induced apoptosis in astrocyte and oligodendrocyte cultures was analysed after Hoechst 33342 fluorostaining. The obtained results indicate that 4BrABT was not toxic to neurons, astrocytes and oligodendrocytes. Moreover, a decrease in the neuronal LDH level was observed, which may suggest the ability of 4BrABT to act as a trophic agent. Furthermore, the protective action of the studied compound was shown in neuronal cultures exposed to neurotoxic conditions (presence of glutamate and trophic stress) and in cisplatin-treated astrocytes and oligodendrocytes. The expression of anticancer and neuroprotective activity raises hopes for the potential use of 4BrABT as a safe anticancer drug, or neuroprotective agent in chemotherapy-associated neurotoxicity.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2013, 20, 3
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Coping strategies observed in women with rheumatoid arthritis
    Autorzy:
    Janiszewska, M.
    Barańska, A.
    Kanecki, K.
    Karpińska, A.
    Firlej, E.
    Bogdan, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/2085883.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    rheumatoid arthritis
    pain
    psychological stress
    coping strategies
    Opis:
    When faced with a chronic disease such as rheumatoid arthritis, the patient attempts to cope with the stressful situation by applying coping strategies. The main aim of rheumatoid treatment is not only improving health but also increasing the quality of life. The research objective was to determine the relationship among socio-demographic factors, duration of the disease and its associated ailments, attitude to the disease, self-assessment of one’s knowledge of RA, and the application of coping strategies in stressful situations by women with rheumatoid arthritis. The study involved 193 patients of the Clinic of Rheumatology and Systemic Connective Tissue Diseases, and the Rheumatology Unit of the Specialist Outpatient Clinic of the Independent Public Teaching Hospital No. 4 in Lublin, from November 2016 – June 2017. The Coping Orientations to Problems Experienced Inventory (COPE) Questionnaire and an author’s Original Questionnaire were used in the study. Analysis of variance (ANOVA) and Tukey’s range test were applied for statistical analysis. A p-value<0.05 defined the statistical differences. Analysis was performed using the commercial SPSS Statistics 19 software (IBM Corp., Armonk, NY, USA). The respondents usually use instrumental social support (11.5±1.7), focus on and vent emotions (11.4±1.9), use emotional social support (11.4±1.8), employ active coping (11.4±2.1) and positive reinterpretation and growth (11.2±1.8), and least often rely on their sense of humour (5.5±1.4) or use alcohol or drugs (5±1.1). The factors which determine the types of strategy used are age, education, the duration of the disease, ailments experienced, and attitude towards the disease. Those respondents who declared a greater knowledge of RA more often applied positive reinterpretation and growth, and more rarely used alcohol or drugs. In the treatment and rehabilitation processes it is important to reinforce in the patient positive expectations for the treatment, seek advantages and benefits in one’s present health status, and educate patients about the disease, its therapy and appropriate coping strategies.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2020, 27, 3; 401-406
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    AlGaAs to GaAs Energy Transfer Mechanisms in AlGaAs/GaAs Structures
    Autorzy:
    Karpińska, K.
    Godlewski, M.
    Żytkiewicz, Z. R.
    Chen, W. M.
    Weber, E. R.
    Powiązania:
    https://bibliotekanauki.pl/articles/1921617.pdf
    Data publikacji:
    1992-10
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    72.20.Jv
    76.70.Hb
    78.55.Cr
    Opis:
    The results of photoluminescence and optically detected cyclotron resonance experiments are presented for thick AlGaAs epilayers grown by liquid phase electroepitaxy method on GaAs:Cr substrate. These results indicate an efficient energy transfer from excited AlGaAs to GaAs.
    Źródło:
    Acta Physica Polonica A; 1992, 82, 4; 713-716
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Optical Characterization of CdZnSe/ZnSe Multiquantum Well System
    Autorzy:
    Godlewski, M.
    Karpińska, K.
    Bergman, J. P.
    Monemar, B.
    Kurtz, E.
    Hommel, D.
    Powiązania:
    https://bibliotekanauki.pl/articles/1932081.pdf
    Data publikacji:
    1995-01
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    68.60.-p
    71.35.+z
    76.70.Hb
    Opis:
    Optical properties of Cd$\text{}_{x}$Zn$\text{}_{1-x}$Se/ZnSe (x = 0.12) multiquantum well system are discussed. The transient photoluminescence and optically detected cyclotron resonance experiments demonstrate a strong contribution of bound exciton emission to the low temperature photoluminescence spectra.
    Źródło:
    Acta Physica Polonica A; 1995, 87, 1; 209-212
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-9 z 9

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