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    Wyświetlanie 1-4 z 4
    Tytuł:
    L-tryptophan and its deriviates in edible mushroom species.
    Autorzy:
    MUSZYŃSKA, Bożena
    KOMENDACKI, Paweł
    KAŁA, Katarzyna
    OPOKA, Włodzimierz
    ROJOWSKI, Jacek
    Powiązania:
    https://bibliotekanauki.pl/articles/1033762.pdf
    Data publikacji:
    2014
    Wydawca:
    Zakład Opieki Zdrowotnej Ośrodek Umea Shinoda-Kuracejo
    Tematy:
    L–tryptophan
    antidepressant agent
    antioxidant activity
    edible mushrooms
    indole compounds
    Opis:
    Mushrooms are able to accumulate both primary and secondary metabolites. Medicinal and antioxidant properties of mushrooms are an excellent combination of their nutrition value. Recent studies have demonstrated that edible mushroom species contain non–hallucinogenic indole compounds and their derivatives. The indole skeleton is the basis of the substances serving important functions in the human body, such as serotonin and melatonin. These compounds fulfill the role of neurotransmitters or their precursors, exhibit antioxidant, anticancer, anti–aging actions, regulate the diurnal cycle in humans and participate in blood coagulation. These compounds and their derivatives are also anti– inflammatory and analgesic therapeutics.
    Źródło:
    Medicina Internacia Revuo; 2014, 26, 103; 82-88
    0465-5435
    Pojawia się w:
    Medicina Internacia Revuo
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Tricholoma equestre species as a source of indole compounds and zinc released into artificial digestive juices
    Autorzy:
    KAŁA, Katarzyna
    SUŁKOWSKA-ZIAJA, Katarzyna
    ROJOWSKI, Jacek
    OPOKA, Włodzimierz
    MUSZYŃSKA, Bożena
    Powiązania:
    https://bibliotekanauki.pl/articles/1034031.pdf
    Data publikacji:
    2016
    Wydawca:
    Zakład Opieki Zdrowotnej Ośrodek Umea Shinoda-Kuracejo
    Tematy:
    "artificial digestive juices"
    "fruiting bodies
    "in vitro culture"
    "zinc"
    Tricholoma equestre"
    indole compounds"
    Opis:
    The research goals of presented work consisted of determination of zinc and indole compounds that are released into artificial digestive juices from Tricholoma equestre species. During the experiment freeze-dried samples of wild growing fruiting bodies and mycelia from in vitro cultures from liquid Oddoux medium were extracted to artificial digestive juices (saliva, gastric juice and intestinal juice). In the next step the determination of examined compounds was done by RP-HPLC for indole compounds and DP ASV for zinc. Furthermore it was decided to check weather this species has any beneficial properties for health. The extraction of researched material in conditions imitating human digestive tract allows determination of true amounts of elements released to artificial digestive juices and their beneficial influence (a specially designed and constructed apparatus Gastroel-2014 was applied). The indole compound with the highest quantity was 5-hydroxy-L-tryptophan, both in fruiting bodies and in biomass from in vitro cultures of T. equestre (up to 352.47 mg/100 g d.w.). Serotonin and L-tryptophan was determined in all analysed samples, but their amounts were significantly lower than the ones found for 5-hydroxy-L-tryptophan. The amounts of zinc on the other hand showed that the biggest concentration of zinc can be obtained for fruiting bodies and biomass from in vitro cultures to both artificial saliva and gastric juice after 120 minutes of digestion (6.83 14.4 mg/100 g d.w. retrospectively) in conditions that imitate human digestive track.
    Źródło:
    Medicina Internacia Revuo; 2016, 27, 106; 35-39
    0465-5435
    Pojawia się w:
    Medicina Internacia Revuo
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Anti-inflammatory activities of garlic sprouts, a source of α-linolenic acid and 5-hydroxy-l-tryptophan, in RAW 264.7 cells
    Autorzy:
    Gdula-Argasińska, Joanna
    Paśko, Paweł
    Sułkowska-Ziaja, Katarzyna
    Kała, Katarzyna
    Muszyńska, Bożena
    Powiązania:
    https://bibliotekanauki.pl/articles/1038621.pdf
    Data publikacji:
    2017
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    Allium sativum sprouts
    indolic and phenolic compounds
    α-linolenic acid
    anti-inflammatory activity
    RAW 264.7 cells
    Opis:
    The purpose of this study was to analyze the indolic, phenolic, and fatty acid content and antioxidant activity of garlic sprouts growing in the dark and in the daylight. The pro- or anti-inflammatory properties of the garlic sprout extract were investigated by evaluating the cyclooxygenase-2 (COX-2), prostaglandin E synthase (cPGES), glutathione S transferase (GSTM1), nuclear factor NF-κB, peroxisome proliferator-activated receptors (PPARs), and aryl hydrocarbon receptor (AhR) protein levels in the RAW 264.7 cells activated with lipopolysaccharide (LPS). The highest amount of total indolic (73.56 mg/100 g f.w.) and phenolic compounds (36.23 mg/100 g f.w.) was detected in garlic sprouts grown in the daylight. Studies on antioxidant activity (the FRAP and DPPH method) of garlic sprouts showed that this activity is significantly higher for sprouts grown in full access to light when compared to those grown in the dark. In garlic sprout extracts, α-linolenic acid (ALA) was found to be in greater amount. COX-2 and cPGES level was lower when compared to LPS alone activated cells. After garlic extract treatment, higher level of GSTM1, PPARΥ, cytosolic p50 and p65 protein, as well as a lower NF-ĸB p50/p65 activity was noted in the RAW 264.7 cells which suggested PPARs and AhR transrepression mechanism of NF-ĸB signalling. The obtained results indicate Allium sativum sprouts are a rich source of n-3 fatty acids, indolic and phenolic compounds characterized by anti-inflammatory and antioxidative activity, which may support their high therapeutic and dietary potential.
    Źródło:
    Acta Biochimica Polonica; 2017, 64, 3; 551-559
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Analysis of the content of phenolic compounds in in vitro culture of some edible mushrooms (Basidiomycota)
    Autorzy:
    Muszyńska, Bożena
    Kała, Katarzyna
    Sułkowska-Ziaja, Katarzyna
    Szewczyk, Agnieszka
    Łojewski, Maciej
    Rojowski, Jacek
    Powiązania:
    https://bibliotekanauki.pl/articles/1033831.pdf
    Data publikacji:
    2015
    Wydawca:
    Zakład Opieki Zdrowotnej Ośrodek Umea Shinoda-Kuracejo
    Tematy:
    agaricus bisporus
    boletus badius
    cantharellus cibarius
    medicinal mushroom
    phenolic
    acids
    Opis:
    Phenolic compounds, both derivatives of benzoic and cinnammic acid, possess biologically valuable properties: anti-inflammatory, antioxidant, anticarcinogenic and others. Studies of the accumulation of these compounds focused mostly on plant material. Rich sources of these compounds are representatives of Basidiomycota taxon. The aim of the study was qualitative and quantitative HPLC analysis of phenolic acids in biomass from in vitro culture of selected edible mushroom species belonging to the phylum Basidiomycota: Agaricus bisporus, Boletus badius, Cantharellus cibarius. The investigations revealed the presence of the following acids: p-hydroxybenzoic, syringic and galic acid. Both the composition and the amount of phenolic acids in biomass of A. bisporus and Boletus badius were diverse. The total amount ranged from 6.07 mg·100 g−1 DW in A. bisporus to 14.78 mg·100 g−1 DW in Boletus badius. Syryngic acid amounts fluctuated in the range of 1.75–9.66 mg·100 g−1 DW, with its maximum in Boletus badius. Gallic acid dominated in the biomass of the same species (5.12 mg·100 g−1 DW). p-Hydroxybenzoic acid was found in biomass from in vitro culture of A. bisporus at levels 0.70 mg/100 g DW. In biomass of in vitro culture of Cantharellus cibarius no phenolic compounds were found before and after hydrolysis. The results of HPLC analyses show that in vitro culture of B. badius and A. bisporus are a good dietary source of phenolic compounds with antioxidant activity.
    Źródło:
    Medicina Internacia Revuo; 2015, 26, 104; 146-152
    0465-5435
    Pojawia się w:
    Medicina Internacia Revuo
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-4 z 4

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