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    Wyświetlanie 1-13 z 13
    Tytuł:
    Myocardial remodeling in rats with metabolic syndrome: role of Rho-kinase mediated insulin resistance
    Autorzy:
    Li, Chuan-Bao
    Li, Xiao-Xing
    Chen, Yu-Guo
    Gao, Hai-Qing
    Bao, Cheng-Mei
    Liu, Xiang-Qun
    Bu, Pei-Li
    Zhang, Juan
    Zhang, Yun
    Ji, Xiao-Ping
    Powiązania:
    https://bibliotekanauki.pl/articles/1039743.pdf
    Data publikacji:
    2012
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    Rat
    Metabolism
    Myocardium
    Phosphorylation
    Insulin resistance
    Opis:
    Insulin resistance (IR) plays a critical role in metabolic syndrome (MS). Previous studies have demonstrated that activated ROCK is increased in MS patients. However, the effect of Rho-kinase (ROCK) on IR has not been definitely determined. Thus, the aims of the present study were to determine whether ROCK activation induces IR or affects myocardial structure and function, as well as the possible mechanisms underlying this process. Wistar rats fed high fat, high glucose and high salt diet sewed as model of MS and we used transmission electron microscopy, echocardiogram technology, and terminal deoxynucleotidyl transferase-mediated DNA nick-end labeling staining to identify any myocardial damage. The protein levels of MYPT-1 (characteristic of ROCK activation), IRS-1 and AKT were analyzed by immunohistochemistry and Western blotting. In hearts from MS rats, we found increased protein levels of phospho-MYPT-1 and phospho-IRS-1 (Ser307) and decreased phospho-AKT compared to levels in normal rats. In conclusion, the results suggest that ROCK-mediated IR is involved in the development of myocardial impairments in MS rats and that this effect is mediated probably via the IRS-1/PI3-kinase/AKT pathway.
    Źródło:
    Acta Biochimica Polonica; 2012, 59, 2; 249-254
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Investigation of the toxicity of the ionic liquid 1-butyl-3-methylimidazolium chloride to Saccharomyces cerevisiae AY93161 for lignocellulosic ethanol production
    Autorzy:
    Zhu, Shengdong
    Yu, Pei
    Lei, Mingke
    Tong, Yanjie
    Zheng, Lu
    Zhang, Rui
    Ji, Jun
    Chen, Qiming
    Wu, Yuanxin
    Powiązania:
    https://bibliotekanauki.pl/articles/778529.pdf
    Data publikacji:
    2013
    Wydawca:
    Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
    Tematy:
    Ionic liquid
    [bmim]Cl
    toxicity
    Saccharomyces cerevisiae AY93161
    lignocellulosic ethanol production
    Opis:
    Ionic liquid (IL) pretreatment of lignocellulosic materials has provided a new technical tool to improve lignocellulosic ethanol production. To evaluate the influence of the residual IL in the fermentable sugars from enzymatic hydrolysis of IL pretreatment of lignocellulosic materials on the subsequent ethanol fermentation, the toxicity of the IL 1-butyl-3-methylimidazolium chloride ([BMIM]Cl) to Saccharomyces cerevisiae AY93161 was investigated. Firstly, the morphological structure, budding and metabolic activity of Saccharomyces cerevisiae AY93161 at different [BMIM]Cl concentrations were observed under an optical microscope. The results show that its single cell morphology remained unchanged at all [BMIM]Cl concentrations, but its reproduction rate by budding and its metabolic activity decreased with the [BMIM]Cl concentration increasing. The half effective concentration (EC50) and the half inhibition concentration (IC50) of [BMIM]Cl to Saccharomyces cerevisiae AY93161 were then measured using solid and liquid suspension culture and their value were 0.53 and 0.39 g.L-1 respectively. Finally, the influence of [BMIM]Cl on ethanol production was investigated. The results indicate that the [BMIM]Cl inhibited the growth and ethanol production of Saccharomyces cerevisiae AY93161. This toxicity study provides useful basic data for further development in lignocellulosic ethanol production by using IL technology and it also enriches the IL toxicity data.
    Źródło:
    Polish Journal of Chemical Technology; 2013, 15, 2; 94-98
    1509-8117
    1899-4741
    Pojawia się w:
    Polish Journal of Chemical Technology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ezetimibe prevents myocardial remodeling in an obese rat model by inhibiting inflammation
    Autorzy:
    Li, Xiao-Xing
    Zhao, Lang
    Chang, Ying
    Liu, Bao-Shan
    Xu, Feng
    Zhang, Cheng
    Ji, Xiao-Ping
    Chen, Yu-Guo
    Li, Chuan-Bao
    Powiązania:
    https://bibliotekanauki.pl/articles/1038380.pdf
    Data publikacji:
    2018
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    obese
    inflammation
    remodeling
    ezetimibe
    IL-6
    Opis:
    Inflammation plays an important role in the development of many obesity-related diseases. This study aimed to investigate the effect of ezetimibe on inflammation and myocardial remodeling in obese rats. A rat model of obesity was established, and myocardial damage was examined by transmission electron microscopy and Masson staining. Twenty obese rats were divided into two groups (n=10): obese group and ezetimibe group. Ten SD rats were used as controls. Western blot was performed to monitor the expression of P-p38MAPK and interleukin (IL)-6. Immunohistochemical staining was used to monitor the expression of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1. In the obese rats group, we observed increased inflammatory factors and myocardial hypertrophy. In contrast, the ezetimibe group exhibited decreased expression of inflammatory factors and an improvement in myocardial remodeling compared to the obese group. Mechanistically, we found that ezetimibe decreased P-p38MAPK, IL-6, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 levels in the hearts of the obese rats. Taken together, these results indicate that ezetimibe may improve myocardial remodeling in obese rats by inhibiting inflammation.
    Źródło:
    Acta Biochimica Polonica; 2018, 65, 3; 465-470
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Adsorption behavior and mechanism of an ether amine collector on collophane and quartz
    Autorzy:
    Fang, Ji
    Ge, Yingyong
    Yu, Jun
    Powiązania:
    https://bibliotekanauki.pl/articles/109589.pdf
    Data publikacji:
    2019
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    adsorption
    collophane
    collector
    ether amine surfactant
    flotation
    Opis:
    The adsorption behaviors of an ether amine surfactant, N1-(3-((8-methyl-nonyl)oxy) propyl)propane-1,3-diamine, on collophane and quartz were studied. Batch adsorption experiments were conducted to characterize the thermodynamic behavior of the adsorption process and to calculate the maximum adsorption. Results demonstrated that the adsorption of the ether amine on quartz was greater than collophane. Adsorption mechanisms were studied by means of contact angle measurement, zeta potential measurement, FT-IR analysis, and X-ray photoelectron spectroscopy. The results showed that the adsorption of the ether amine surfactant on quartz surface was easier and more efficient than collophane. Micro-flotation tests testified that the collector can efficiently separate collophane from quartz at room temperature in neutral medium.
    Źródło:
    Physicochemical Problems of Mineral Processing; 2019, 55, 1; 301-310
    1643-1049
    2084-4735
    Pojawia się w:
    Physicochemical Problems of Mineral Processing
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Dual Speed Laser Remelting for High Densification in H13 Tool Steel Metal 3D Printing
    Autorzy:
    Jung, Im Doo
    Choe, Jungho
    Yun, Jaecheol
    Yang, Sangsun
    Yang, Dong-Yeol
    Kim, Yong-Jin
    Yu, Ji-Hun
    Powiązania:
    https://bibliotekanauki.pl/articles/353737.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    metal 3d printing
    powder bed fusion
    selective laser melting
    H13 tool steel
    remelting
    Opis:
    The densification behavior of H13 tool steel powder by dual speed laser scanning strategy have been characterized for selective laser melting process, one of powder bed fusion based metal 3d printing. Under limited given laser power, the laser re-melting increases the relative density and hardness of H13 tool steel with closing pores. The single melt-pool analysis shows that the pores are located on top area of melt pool when the scanning speed is over 400 mm/s while the low scanning speed of 200 mm/s generates pores beneath the melt pool in the form of keyhole mode with the high energy input from the laser. With the second laser scanning, the pores on top area of melt pools are efficiently closed with proper dual combination of scan speed. However pores located beneath the melt pools could not be removed by second laser scanning. When each layer of 3d printing are re-melted, the relative density and hardness are improved for most dual combination of scanning. Among the scan speed combination, the 600 mm/s by 400 mm/s leads to the highest relative density, 99.94% with hardness of 53.5 HRC. This densification characterization with H13 tool steel laser re-melting can be efficiently applied for tool steel component manufacturing via metal 3d printing.
    Źródło:
    Archives of Metallurgy and Materials; 2019, 64, 2; 571-578
    1733-3490
    Pojawia się w:
    Archives of Metallurgy and Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Fabrication of 4N5 Grade Tantalum Wire from Tantalum Scrap by EBM and Drawing
    Autorzy:
    Yu, Ji-Won
    Choi, Sang-Hoon
    Sim, Jae-Jin
    Lim, Jae-Hong
    Seo, Kyoung-Deok
    Hyun, Soong-Keon
    Kim, Tae-Youb
    Gu, Bon-Woo
    Park, Kyoung-Tae
    Powiązania:
    https://bibliotekanauki.pl/articles/353005.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    electron beam melting
    drawing
    tantalum scrap
    recycling
    high purity
    Opis:
    Electron beam melting(EBM) is a useful technique to obtain high-purity metal ingots. It is also used for melting refractory metals such as tantalum, which require melting techniques employing a high-energy heat source. Drawing is a method which is used to convert the ingot into a wire shape. The required thickness of the wire is achieved by drawing the ingot from a drawing die with a hole of similar size. This process is used to achieve high purity tantalum springs, which are an essential component of lithography lamp in semiconductor manufacturing process. Moreover, high-purity tantalum is used in other applications such as sputtering targets for semiconductors. Studies related to recycling of tantalum from these components have not been carried outuntil now. The recycling of tantalum is vital for environmental and economic reasons. In order to obtain high-purity tantalum ingot, in this study impurities contained in the scrap were removed by electron beam melting after pre-treatment using aqua regia. The purity of the ingot was then analyzed to be more than 4N5 (99.995%). Subsequently, drawing was performed using the rod melted by electron beam melting. Owing to continuous drawing, the diameter of the tantalum wire decreased to 0.5 mm from 9 mm. The hardness and oxygen concentration of the tantalum ingot were 149 Hv and less than 300 ppm, respectively, whereas the hardness of the tantalum wire was 232.12 Hv. In conclusion, 4N5 grade tantalum wire was successfully fabricated from tantalum scrap by EBM and drawing techniques. Furthermore, procedure to successfully recycle Tantalum from scraps was established.
    Źródło:
    Archives of Metallurgy and Materials; 2019, 64, 3; 935-941
    1733-3490
    Pojawia się w:
    Archives of Metallurgy and Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    FERMENTED ORIENTAL MEDICINAL INSECT EXTRACT HAS A SYNERGISTIC EFFECT ON INHIBITING TGF-ß1- OR H2O2-INDUCED HEPATIC FIBROGENESIS IN LX-2 AND HEPG2 CELLS
    Autorzy:
    Choo, Young-Moo
    Choi, Young-Ji
    Park, In-Sun
    Son, Yu-Kyog
    You, Kang-Yeol
    Kim, Jiyoung
    Powiązania:
    https://bibliotekanauki.pl/articles/895380.pdf
    Data publikacji:
    2019-06-28
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 3; 599-603
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Leaching kinetics of iron from coal-series kaolin by oxalic acid solutions
    Autorzy:
    Shao, Hui
    Ji, Mengjiao
    Yu, Mingming
    Powiązania:
    https://bibliotekanauki.pl/articles/1449978.pdf
    Data publikacji:
    2020
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    coal-series kaolin
    leaching kinetics
    iron removal rate
    oxalic acid
    Opis:
    Removal of iron from coal-series kaolinite and its kinetics by chemical leaching were investigated in this paper. The optimal removal rate of iron reaches 29.09% (the content of $Fe_2O_3$ decreased from 0.55 to 0.39%) under the conditions of 100 °C, 0.4 M $C_2H_2O_4$, and liquid-to-solid ratio of 4 cm3/g for 120 min. The leaching process was successfully described by the Avrami model and mainly controlled by internal diffusion control of shrinking core model, the apparent activation energy is 18.46 kJ/mol. The experimental results were consistent with the internal diffusion control of shrinking core model, improving acid concentration and leaching temperature could promotes the removal of iron from coal-series kaolin.
    Źródło:
    Physicochemical Problems of Mineral Processing; 2020, 56, 1; 134-146
    1643-1049
    2084-4735
    Pojawia się w:
    Physicochemical Problems of Mineral Processing
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Heat Treatment Effect on Physical Properties of Stainless Steel / Inconel Bonded by Directed Energy Deposition
    Autorzy:
    Eom, Yeong Seong
    Kim, Kyung Tae
    Kim, Dong Won
    Yu, Ji-Hun
    Sim, Chul Yong
    An, Seung Jun
    Park, Yong-Ha
    Son, Injoon
    Powiązania:
    https://bibliotekanauki.pl/articles/2049122.pdf
    Data publikacji:
    2021
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    directed energy deposition
    interface
    physical properties
    heat treatment
    Opis:
    In this study, stainless steel 316L and Inconel 625 alloy powders were additively manufactured by using directed energy deposition process. And heat treatment effect on hardness and microstructures of the bonded stainless steel 316L/Inconel 625 sample was investigated. The microstructures shows there are no secondary phases and big inclusions near interfacial region between stainless steel 316L and Inconel 625 except several small cracks. The results of TEM and Vickers Hardness show the interfacial area have a few tens of micrometers in thickness. Interestingly, as the heat treatment temperature increases, the cracks in the stainless steel region does not change in morphology while both hardness values of stainless steel 316L and Inconel 625 decrease. These results can be used for designing pipes and valves with surface treatment of Inconel material based on stainless steel 316L material using the directed energy deposition.
    Źródło:
    Archives of Metallurgy and Materials; 2021, 66, 4; 1049-1054
    1733-3490
    Pojawia się w:
    Archives of Metallurgy and Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    High-Efficiency Cooling System Using Additive Manufacturing
    Autorzy:
    Woo, Yeong-Jin
    Nam, Dong-Ho
    Lee, Seok-Rok
    Kim, Eun-Ah
    Lee, Woo-Jin
    Yang, Dong-Yeol
    Yu, Ji-Hun
    Park, Yong-Ho
    Lee, Hak-Sung
    Powiązania:
    https://bibliotekanauki.pl/articles/2049198.pdf
    Data publikacji:
    2021
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    additive manufacturing
    DfAM
    Design for Additive Manufacturing
    cooling system
    lattice structure
    simulation
    Opis:
    In this study, we propose a cooling structure manufactured using a specialized three-dimensional (3D) printing design method. A cooling performance test system with complex geometry that used a thermoelectric module was manufactured using metal 3D printing. A test model was constructed by applying additive manufacturing simulation and computational fluid analysis techniques, and the correlation between each element and cooling efficiency was examined. in this study, the evaluation was conducted using a thermoelectric module base cooling efficiency measurement system. The contents were compared and analyzed by predicting the manufacturing possibility and cooling efficiency, through additive manufacturing simulation and computational fluid analysis techniques, respectively.
    Źródło:
    Archives of Metallurgy and Materials; 2021, 66, 3; 689-693
    1733-3490
    Pojawia się w:
    Archives of Metallurgy and Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Investigations on a novel collector for anionic reverse flotation separation of quartz from iron ores
    Autorzy:
    Fang, Ji
    Ge, Yingyong
    Liu, Shunbing
    Yu, Jun
    Liu, Cheng
    Powiązania:
    https://bibliotekanauki.pl/articles/1448585.pdf
    Data publikacji:
    2021
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    reverse flotation
    iron ore
    quartz
    collector
    fatty acid
    Opis:
    It is necessary to exploit an easy and effective way to obtain flotation collector. In this paper, oleic acid was modified by oxidation reaction to obtain an excellent collector. The flotation performances of oleic acid and its oxidation products were systematically investigated and a novel collector ((E)-8,11-dihydroperoxyoctadec-9-enoic acid, EDEA) was obtained. Single mineral flotation tests results showed that EDEA had strong flotation power towards quartz at pH＞11 and hardly floated hematite and magnetite at pH=8~13. The recovery of quartz could achieve 92.35% with 120 mg/L EDEA under the condition of pH=12 and dosage of $CaCl_2$ 60mg/L while the recovery was 62.44% with 120 mg/L oleic acid. Bench scale flotation tests results showed that EDEA had a preferable effect on separating quartz from iron ore especially at low flotation temperature (288K). The mechanism research revealed that EDEA attracted on quartz surface through electrostatic attraction and the neighboring EDEA molecules could form intermolecular hydrogen bonds which resulted in a closer alignment of EDEA on quartz surface.
    Źródło:
    Physicochemical Problems of Mineral Processing; 2021, 57, 1; 136-155
    1643-1049
    2084-4735
    Pojawia się w:
    Physicochemical Problems of Mineral Processing
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Simulating the effects of refractive index difference on the coupling efficiency of periodically segmented waveguide mode converter
    Autorzy:
    Zheng, Yu
    He, Hao
    Jiang, Lianqiong
    Duan, Ji'an
    Powiązania:
    https://bibliotekanauki.pl/articles/2033880.pdf
    Data publikacji:
    2021
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    coupling efficiency
    silica waveguide
    planar lightwave circuit
    micro-optical waveguide
    nano-optical waveguide
    Opis:
    Efficient coupling of micro/nano-optical waveguides with single-mode fibers is the premise for the efficient operation of the integrated photonic chip, which directly determines its optical performance. In this paper, the design principles of periodically segmented waveguide (PSW) structure used for high-efficiency fiber-chip coupling are proposed, and the effects of refractive index difference Δ on coupling efficiency and structural parameters are studied by simulation. It is found that as the Δ of the PSW increases, the period of the PSW tends to be smaller, and the coupling efficiency decreases continuously, reduced by around 0.673 dB in the range of Δ = 3% to Δ = 7%. Through the analysis of PSW optical mechanisms, it demonstrates that the main reason for the decrease of coupling efficiency is that the transmission loss of the tapered section increases sharply with the increase of Δ. High-Δ PSW is difficult to apply to highly integrated silica optical chips due to the unignorably insertion loss.
    Źródło:
    Optica Applicata; 2021, 51, 4; 565-577
    0078-5466
    1899-7015
    Pojawia się w:
    Optica Applicata
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    High-security image encryption by multiplexing phase encoding in domains of dual optical transforms
    Autorzy:
    Li, Zhihui
    Gao, Bin
    Pan, Xiaoou
    Li, Linlin
    Wang, Chenxuan
    Zuo, Weizhuo
    Ji, Yu
    Liu, Shutian
    Liu, Zhengjun
    Powiązania:
    https://bibliotekanauki.pl/articles/27310099.pdf
    Data publikacji:
    2023
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    extended fractional Fourier transform
    geometric operations
    random phase encoding
    Opis:
    A novel optical image encryption is proposed based on multiplexing of the random phase encoding with shift and rotation operations in domains of two transforms, extended fractional Fourier transform (eFrFT) and Fresnel transform. The original image is subjected to eFrFT with the action of the random phase mask. The mask is shifted and rotated to enhance the security of this encryption method. The image obtained from eFrFT is entered into Fresnel diffraction by the use of the phase mask to obtain the final encrypted image. We plan for the phase keys to be multiplexed in order to decrease the amount of keys that need to be stored in an application. Here, the displacement, rotation angle, and wavelength in this system can be used as additional keys to improve the security and reliability of the encryption system. Numerical experiments are conducted to verify the effectiveness and security of the method. The findings demonstrate that the keys are sufficiently sensitive for high security.
    Źródło:
    Optica Applicata; 2023, 53, 3; 447--466
    0078-5466
    1899-7015
    Pojawia się w:
    Optica Applicata
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-13 z 13

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