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    Tytuł:
    A novel method to calculate the mechanical properties of cancer cells based on atomic force microscopy
    Autorzy:
    Zhang, T
    Zhao, Y.
    Tong, Z.
    Guang, Y.
    Powiązania:
    https://bibliotekanauki.pl/articles/307289.pdf
    Data publikacji:
    2016
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    właściwości mechaniczne
    AFM
    moduł Younga
    cells’ mechanical properties
    eliminating thermal drift
    Young's modulus
    differential Hertz’s model
    Opis:
    Purpose: Mechanical properties, as the inherent characteristics of cells, play a critical role in many essential physiological processes, including cell differentiation, migration, and growth. The mechanical properties of cells are one of the criteria that help to determine whether the tissue contains lesions at the single cell level, and it is very important for the early prevention and accurate diagnosis of diseases. Atomic force microscopy (AFM) makes it possible to measure the mechanical properties at single cell level in physiological state. This paper presents a novel method to calculate the mechanical properties of cancer cells more accurately through Atomic force microscopy. Methods: A new induced equation of Hertz’s model, called differential Hertz’s model, has been proposed to calculate the mechanical properties of cancer cells. Moreover, the substrate effect has also been effectively reduced through comparing the calculated mechanical properties of cell at different cell surface areas. Results: The results indicate that the method utilized to calculate the mechanical properties of cells can effectively eliminate the errors in calculation, caused by the thermal drift of AFM system and the substrate effect, and thus improve the calculation accuracy. Conclusion: The mechanical properties calculated by our method in this study are closer to the actual value. Thus, this method shows potential for use in establishing a standard library of Young’s modulus.
    Źródło:
    Acta of Bioengineering and Biomechanics; 2016, 18, 1; 19-24
    1509-409X
    2450-6303
    Pojawia się w:
    Acta of Bioengineering and Biomechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Calculation and measurement of tide height for the navigation of ship at high tide using artificial neural network
    Autorzy:
    Li, Q.
    Bing-Dong, Y.
    Bi-Guang, H.
    Powiązania:
    https://bibliotekanauki.pl/articles/258480.pdf
    Data publikacji:
    2018
    Wydawca:
    Politechnika Gdańska. Wydział Inżynierii Mechanicznej i Okrętownictwa
    Tematy:
    deep-draft ships
    neural network
    intelligent navigation
    multi-observation stations
    Opis:
    Accurate tide height is crucial for the safe navigation of large deep-draft ships when they enter and leave the port. We have proposed an accurate forecasting method for the tide heights from the observation data and neural networks, which can easily calculate the tidal window period of large deep-draft ships’ navigation through long channels at high tide. Moreover, an artificial neural network is established for the tide height from the observation of tide heights before their current time node. For an ideal forecast, the neural network was optimized for one year with the tide height data of Huanghua Port. In case of large ships, their tidal characteristics of channels for are complex. A new method is proposed for the observation of multiple stations and artificial neural networks of each observation station. When ships are navigating through the port, the tide height is predicted from the observed data and forecast tide heights of multiple observation stations. Thus, a valid tidal window period is secured when the ships enter the port. Comparative analysis of the ship’s tidal window period with that of the measured one can lead us to conclude that the forecasted data has a strong correlation with the measurement. So, our proposed algorithm can accurately predict the tide height and calculate the node timing when the ship enters and depart the port. Finally, these results can be applied for the safe navigation of large deep-draft ships when the port is at high tide.
    Źródło:
    Polish Maritime Research; 2018, S 3; 99-110
    1233-2585
    Pojawia się w:
    Polish Maritime Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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