- Tytuł:
- Implementation and evaluation of new protocol for comparative modeling of protein structures
- Autorzy:
-
Strumillo, M.
Dawid, A. E.
Szczasiuk, A.
Gront, D. - Powiązania:
- https://bibliotekanauki.pl/articles/1935813.pdf
- Data publikacji:
- 2014
- Wydawca:
- Politechnika Gdańska
- Tematy:
-
protein structure prediction
comparative modeling
protein threading
protein alignment
BioShell
Rosetta
przewidywanie struktury białek
modelowanie porównawcze
gwintowania białka
wyrównanie białka - Opis:
- Template-based modeling (termed also Comparative or Homology Modeling) of a protein structure is one of ubiquitous tasks of structural bioinfor matics. The method can deliver model structures important for testing biological hypotheses, virtual docking and drug design. The performance of these methods is evaluated every two years during a Critical Assessment of Protein Structure Prediction (CASP) experiment. In this contribution we present a new automated protocol for template-base d modeling, which combines computational tools recently developed in our laboratory: the dat abase of protein domain structures (BDDB) with one dimensional and three dimensional thread ing applications. The protocol was tested during a CASP11 experiment.
- Źródło:
-
TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk; 2014, 18, 4; 379--384
1428-6394 - Pojawia się w:
- TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk
- Dostawca treści:
- Biblioteka Nauki
Artykuł