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    Wyświetlanie 1-4 z 4
    Tytuł:
    System matrix computation for iterative reconstruction algorithms in SPECT based on direct measurements
    Autorzy:
    Borys, D.
    Szczucka-Borys, K.
    Gorczewski, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/907829.pdf
    Data publikacji:
    2011
    Wydawca:
    Uniwersytet Zielonogórski. Oficyna Wydawnicza
    Tematy:
    SPECT
    metoda iteracyjna
    obrazowanie ilościowe
    iterative reconstruction
    quantitative imaging
    Opis:
    A method for system matrix calculation in the case of iterative reconstruction algorithms in SPECT was implemented and tested. Due to a complex mathematical description of the geometry of the detector set-up, we developed a method for system matrix computation that is based on direct measurements of the detector response. In this approach, the influence of the acquisition equipment on the image formation is measured directly. The objective was to obtain the best quality of reconstructed images with respect to specified measures. This is indispensable in order to be able to perform reliable quantitative analysis of SPECT images. It is also especially important in non-hybrid gamma cameras, where not all physical processes that disturb image acquisition can be easily corrected. Two experiments with an 131I point source placed at different distances from the detector plane were performed allowing the detector response to be acquired as a function of the point source distance. An analytical Gaussian function was fitted to the acquired data in both the one- and the two-dimensional case. A cylindrical phantom filled with a water solution of 131I containing a region of 'cold' spheres as well as a uniform solution (without any spheres) was used to perform algorithm evaluation. The reconstructed images obtained by using four different of methods system matrix computation were compared with those achieved using reconstruction software implemented in the gamma camera. The contrast of the spheres and uniformity were compared for each reconstruction result and also with the ranges of those values formulated by the AAPM (American Association of Physicists in Medicine). The results show that the implementation of the OSEM (Ordered Subsets Expectation Maximization) algorithm with a one-dimensional fit to the Gaussian CDR (Collimator-Detector Response) function provides the best results in terms of adopted measures. However, the fit of the two-dimensional function also gives satisfactory results. Furthermore, the CDR function has the potential to be applied to a fully 3D OSEM implementation. The lack of the CDR in system matrix calculation results in a very noisy image that cannot be used for diagnostic purposes.
    Źródło:
    International Journal of Applied Mathematics and Computer Science; 2011, 21, 1; 193-202
    1641-876X
    2083-8492
    Pojawia się w:
    International Journal of Applied Mathematics and Computer Science
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    E.Cam DUET gamma camera model validation in GATE
    Autorzy:
    Borys, D.
    Szczucka, K.
    Gorczewski, K.
    Bekman, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/333872.pdf
    Data publikacji:
    2007
    Wydawca:
    Uniwersytet Śląski. Wydział Informatyki i Nauki o Materiałach. Instytut Informatyki. Zakład Systemów Komputerowych
    Tematy:
    symulacja Monte Carlo
    GATE
    model gamma-kamera
    Monte Carlo simulation
    gamma camera model
    99mTc
    Opis:
    Monte Carlo simulations are more and more popular trend in nuclear medicine imaging. They were also widely used in radiotherapy and brachytherapy with use of more general simulation software. GATE (Geant4 Application for Tomographic Emission) is a platform developed on general Monte Carlo code designed for simulating and tracking the passage of particles through matter (Geant4) but is specifically designed for nuclear medicine imaging purposes. The aim of this work was to create and validate a model of specific gamma-camera (E.Cam DUET), used in our department, for further use in image analysis and dosimetry field, with GATE simulation platform. We have modeled in first step a point source in the air in three configurations of gamma camera (without collimator, with low-energy high-resolution (LEHR) collimator and with high-energy (HE collimator)), then we have created a phantom with three spherical sources of different sizes but with the same concentration of the radiopharmaceutical. Simulation results were compared to the measured values of the energy spectrum and images obtained on the detectors, and show a good agreement for the point source experiments and revealed some differences for the phantom studies. This results shows that some additional tests and refinements are required but also allows us to study the image degrading quality factors, such as septal penetration and to work towards eliminating them from the pictures.
    Źródło:
    Journal of Medical Informatics & Technologies; 2007, 11; 245-252
    1642-6037
    Pojawia się w:
    Journal of Medical Informatics & Technologies
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    CT/SPECT image fusion in patients treated with iodine-131
    Autorzy:
    Psiuk-Maksymowicz, K.
    Borys, D.
    Gorczewski, K.
    Steinhof, K.
    d'Amico, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/333051.pdf
    Data publikacji:
    2004
    Wydawca:
    Uniwersytet Śląski. Wydział Informatyki i Nauki o Materiałach. Instytut Informatyki. Zakład Systemów Komputerowych
    Tematy:
    połączenie obrazu
    emisyjna tomografia komputerowa pojedynczego fotonu
    image fusion
    SPECT-CT overlay
    point-based method
    Opis:
    Computer tomography gives visualization of anatomical structures and abnormalities, but it lacks of functional information. On the other hand, single photon emission tomography provides the missing information about the tumour function, but it has relative low resolution and the localization of the visible focus may be difficult, especially when iodine ¹³¹I is used. Thus, several methods of image fusion are applied. We present an algorithm of image fusion based on affine transformation. On the base of a phantom study, we showed that the created program can be a useful tool to fuse CT and SPECT images and then applied to patients' datasets. External marker method was used to align patient functional and anatomical data. Image alignment quality depends on appropriate marker placement and acquisition protocol. The program estimates maximal misalignment in a volume between the markers. Created acquisition protocol minimizes misalignment of patient placement on both CT and gamma camera, however misalignment derived from respiratory movements cannot be avoided. The proposed technique is simple, low-cost and can be easily adopted in any hospital or diagnostic centre equipped with gamma camera and CT. Fusion of morphology and function can improve diagnostic accuracy in many clinical circumstances.
    Źródło:
    Journal of Medical Informatics & Technologies; 2004, 8; II7-12
    1642-6037
    Pojawia się w:
    Journal of Medical Informatics & Technologies
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-4 z 4

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