- Tytuł:
- Physical properties of materials used for infusion sets for photosensitive medicines
- Autorzy:
-
Szafarczyk, Karolina
Szewczenko, Janusz
Maciak, Erwin
Kałużyński, Piotr
Goldsztajn, Karolina - Powiązania:
- https://bibliotekanauki.pl/articles/27324033.pdf
- Data publikacji:
- 2022
- Wydawca:
- Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
- Tematy:
-
infusion drains
photosensitive medicines
polyvinyl chloride
UV-VIS spectrophotometry
transmittance
absorbance
spektrofotometria
biomateriały
medycyna
polichlorek winylu - Opis:
- Continuous infusion, as one of the most effective methods of delivering pharmaceuticals to patients, uses infusion pumps to which a syringe and infusion drains are connected. Photosensitive drugs that require UV-VIS protection are delivered to patients with special infusion sets that reduce harmful radiation. However, these drains have different transparencies, which can affect the success of therapy. This study investigated the optical properties of two types of drains used for infusion therapy of photosensitive drugs. UV-VIS spectroscopy studies were carried out, allowing the determination of the absorbance values and absorption coefficient of the two types of drains. The spectrum of their transmittance was also analyzed. The chemical composition of the samples was tested using FTIR-ATR spectroscopy. Furthermore, the roughness and wettability parameters of the drains were determined, which affect not only the kinematics of drug flow in the drains but also the way in which light is transmitted. The results of the study can be used to propose a solution to eliminate the problem of loss of properties of the photosensitive drug in drains, in contact with light. By selecting the appropriate drain thickness, it is possible to reduce the transmission of radiation in the UV-VIS range through the drain.
- Źródło:
-
Engineering of Biomaterials; 2022, 25, 167; 2--9
1429-7248 - Pojawia się w:
- Engineering of Biomaterials
- Dostawca treści:
- Biblioteka Nauki
Artykuł