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Wyświetlanie 1-2 z 2
Tytuł:
Współczesne motywacje imiennicze w województwie podlaskim na podstawie badań ankietowych
Modern naming motivations on the questionnaire survey material
Autorzy:
Gawroń, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/40255669.pdf
Data publikacji:
2022
Wydawca:
Uniwersytet w Białymstoku. Wydawnictwo Uniwersytetu w Białymstoku
Tematy:
anthroponymy
naming motivations
given name
questionnaire survey
Opis:
The present paper attempts to establish the motives behind baby‑naming trends and parents’ choices in the recent years (2018–2021). It also aims to present the repertoire of the names of children aged 0–2 collected by means of a questionnaire created for the purposes of this research study. The repertoires of female and male children’s names were compared with those of their parents’, which allowed for determining differences and presenting the changes in naming trends over the two generations. The questionnaire created at the platform https://www.interankiety.pl was widespread in Facebook groups focusing on pregnancy, labour and maternity. It was active from the 18th November to the 6th December 2020. A semantic and quantitative analysis showed that the collected material reflects the current fashion in naming: the most popular onyms in the repertoire of names from the parents’ generation, Łukasz and Anna, do not occur in that of children’s names. Conversely, the most popular children’s names, Jan and Zuzanna, were not recorded in the collection of parents’ names. The materialattests to the growing popularity of multiple names and an increasing variety of onyms, which is corroborated by a large number of individual names in the analysed corpus. Parents’ responses concerning naming motivations show that subjectively interpreted aesthetic considerations dominate (65%), followed by the combination of first names and the last name (34%). The third most popular factor was the possibility of shortening names and creating diminutives (31%). Other responses to the closed questions and many extensive answers to the open questions prove that baby‑naming is very important to the modern parent. Parents’ motivations are complex and multifaceted, significantly different from the Old Polish naming practices, as shown by the analysed data.
Źródło:
Białostockie Archiwum Językowe; 2022, 22; 61-81
1641-6961
Pojawia się w:
Białostockie Archiwum Językowe
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Influence of vitamin D3 analogues in combination with budesonid R on proliferation of nasal polyp fibroblasts
Autorzy:
Rostkowska-Nadolska, Beata
Frączek, Marcin
Gawron, Wojciech
Latocha, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/1040569.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
vitamin D3
nasal polyps
tacalcitol
fibroblast
calcitriol
budesonid R
proliferation
Opis:
Vitamin D (VD) and its different analogues, besides their classic role as regulators of calcium and phosphor homeostasis, have emerged as a large family of antiproliferative agents. Such properties suggested VD potential as a therapy for chronic inflammatory diseases, including nasal polyposis (NP). NP growth involves both an inflammatory process and the proliferation of fibroblast as an important factor inducing aberrations in the phenotype of the epithelium. The aim of this study was to investigate the possible influence of 1α,25-dihydroxyvitamin D3 (calcitriol) and 1α,24(R)-dihydroxyvitamin D3 (tacalcitol) in monotherapy and in combination with budesonid R (BR) on NP fibroblast proliferation. Material and methods: The study involved 26 samples of NP. NP cells were cultured on 96-well plates beginning with a concentration of 5 × 103 cells per well with RPMI 1640 medium supplemented with antibiotics and 10% foetal bovine serum. After the fourth to sixth passage the medium was replaced with a nutrient medium with calcitriol or tacalcitol in a defined concentration (from 10-9 M to 10-3 M) alone or in combination with BR in 1:1, 1:3 or 3:1 ratios, each at concentrations from 10-5 M to 10-3 M. Results: Growth inhibition of nasal fibroblasts exposed to calcitriol or tacalcitol was noted. Significant antiproliferating activity was observed at calcitriol concentrations of 10-4 M and 10-3 M after 48 h, and at a concentration of 10-3 M after 72 h with the percentage of proliferating cells reduced to 30% compared to the control samples (P < 0.05). In cells treated with tacalcitol the maximal effect was seen at 10-4 M after 48 h and at 10-3M after 72 h with a 60% inhibition with respect to the control (P < 0.05). The inhibition of fibroblast proliferation reached the maximal level when they were exposed to calcitriol: BR (1 : 1) or tacalcitol: BR (1 : 1), each at a concentration of 10-4 M, after 72 h (82% and 69%, respectively). Conclusions: The antiproliferative activity of calcitriol and tacalcitol in NP cultures was confirmed. Because of its lower toxicity and higher activity tacalcitol seems to be the more promising agent in NP therapy, both as a single medication and in treatment protocols with BR.
Źródło:
Acta Biochimica Polonica; 2009, 56, 2; 235-242
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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