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    Wyświetlanie 1-8 z 8
    Tytuł:
    Temperature Monitoring during Focused Ultrasound Treatment by Means of the Homodyned K Distribution
    Autorzy:
    Byra, M.
    Kruglenko, E.
    Gambin, B.
    Nowicki, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/1032313.pdf
    Data publikacji:
    2017-06
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    temperature monitoring
    homodyned K distribution
    focused ultrasound
    Opis:
    Temperature monitoring is essential for various medical treatments. In this work, we investigate the impact of temperature on backscattered ultrasound echo statistics during a high intensity focused ultrasound treatment. A tissue mimicking phantom was heated with a spherical ultrasonic transducer up to 56°C in order to imitate tissue necrosis. During the heating, an imaging scanner was used to acquire backscattered echoes from the heated region. These data was then modeled with the homodyned K distribution. We found that the best temperature indicator can be obtained by combining two parameters of the model, namely the backscattered echo mean intensity and the effective number of scatterers per resolution cell. Next, ultrasonic thermometer was designed and used to create a map of the temperature induced within the tissue phantom during the treatment.
    Źródło:
    Acta Physica Polonica A; 2017, 131, 6; 1525-1528
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Sensitivity analysis of mathematical models of signalling pathways
    Autorzy:
    Charzynska, A.
    Nalecz, A.
    Rybinski, M.
    Gambin, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/80205.pdf
    Data publikacji:
    2012
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    membrane receptor
    differential equation
    stochastic model
    modelling
    sensitivity analysis
    mathematical model
    signalling pathway
    dynamic behaviour
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2012, 93, 3
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ultrasonic Measurement of Temperature Rise in Breast Cyst and in Neighbouring Tissues as a Method of Tissue Differentiation
    Autorzy:
    Gambin, B.
    Byra, M.
    Kruglenko, E.
    Doubrovina, O.
    Nowicki, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/177465.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    medical ultrasound
    temperature changes in vivo
    breast tissue
    ultrasonic temperature measurement
    Opis:
    Texture of ultrasound images contain information about the properties of examined tissues. The analysis of statistical properties of backscattered ultrasonic echoes has been recently successfully applied to differentiate healthy breast tissue from the benign and malignant lesions. We propose a novel procedure of tissue characterization based on acquiring backscattered echoes from the heated breast. We have proved that the temperature increase inside the breast modifies the intensity, spectrum of the backscattered signals and the probability density function of envelope samples. We discuss the differences in probability density functions in two types of tissue regions, e.g. cysts and the surrounding glandular tissue regions. Independently, Pennes bioheat equation in heterogeneous breast tissue was used to describe the heating process. We applied the finite element method to solve this equation. Results have been compared with the ultrasonic predictions of the temperature distribution. The results confirm the possibility of distinguishing the differences in thermal and acoustical properties of breast cyst and surrounding glandular tissues.
    Źródło:
    Archives of Acoustics; 2016, 41, 4; 791-798
    0137-5075
    Pojawia się w:
    Archives of Acoustics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    A stable density approach to probe selection for a custom aCGH design
    Autorzy:
    Gambin, T.
    Stankiewicz, P.
    Gambin, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/81185.pdf
    Data publikacji:
    2011
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    genomic region
    probe
    copy number alternation
    comparative genomic hybridization
    human genome
    microarray
    wide range application
    gene expression
    methylation
    binding protein
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2011, 92, 3
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Optimization algorithm for de novo analysis of tandem mass spectrometry data
    Autorzy:
    Kistowski, M.
    Gambin, A,
    Powiązania:
    https://bibliotekanauki.pl/articles/80400.pdf
    Data publikacji:
    2011
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    algorithm
    tandem mass spectrometry
    analysis
    protein identification
    post-translational protein modification
    amino acid sequence
    genetic algorithm
    mass spectrometry
    liquid chromatography
    mutation
    crossing-over
    Lutefisk algorithm
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2011, 92, 3
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ultrasonic Synthetic Apertures: Review
    Autorzy:
    Nowicki, A.
    Gambin, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/176456.pdf
    Data publikacji:
    2014
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    synthetic aperture
    effective aperture
    ultrasonography
    Opis:
    In the paper the concept of synthetic aperture used for high resolution/high frame rate ultrasonic imaging is reviewed. The synthetic aperture technique allows building extended “virtual” apertures, synthesized from smaller real aperture resulting in improved lateral resolution along full penetration depth without sacrificing the frame rate. Especially, four methods, synthetic aperture focusing (SAF), multi-element synthetic aperture focusing (M-SAF), synthetic receive aperture (SRA) and synthetic transmit aperture (STA) are addressed. The effective aperture function, describing two-way, far field radiation is a useful tool in beam pattern analysis. Some basic notations, which are used to calculate the effective aperture are introduced in Appendix.
    Źródło:
    Archives of Acoustics; 2014, 39, 4; 427-438
    0137-5075
    Pojawia się w:
    Archives of Acoustics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Efficient alternatives to PSI-BLAST
    Autorzy:
    Startek, M.
    Lasota, S.
    Sykulski, M.
    Bułak, A.
    Noé, L.
    Kucherov, G.
    Gambin, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/201603.pdf
    Data publikacji:
    2012
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    PSI BLAST tool
    sequence alignment
    seeding technique
    Opis:
    In this paper we present two algorithms that may serve as efficient alternatives to the well-known PSI BLAST tool: SeedBLAST and CTX-PSI Blast. Both may benefit from the knowledge about amino acid composition specific to a given protein family: SeedBLAST uses the advisedly designed seed, while CTX-PSI BLAST extends PSI BLAST with the context-specific substitution model. The seeding technique became central in the theory of sequence alignment. There are several efficient tools applying seeds to DNA homology search, but not to protein homology search. In this paper we fill this gap. We advocate the use of multiple subset seeds derived from a hierarchical tree of amino acid residues. Our method computes, by an evolutionary algorithm, seeds that are specifically designed for a given protein family. The seeds are represented by deterministic finite automata (DFAs) and built into the NCBI-BLAST software. This extended tool, named SeedBLAST, is compared to the original BLAST and PSI-BLAST on several protein families. Our results demonstrate a superiority of SeedBLAST in terms of efficiency, especially in the case of twilight zone hits. The contextual substitution model has been proven to increase sensitivity of protein alignment. In this paper we perform a next step in the contextual alignment program. We announce a contextual version of the PSI-BLAST algorithm, an iterative version of the NCBI-BLAST tool. The experimental evaluation has been performed demonstrating a significantly higher sensitivity compared to the ordinary PSI-BLAST algorithm.
    Źródło:
    Bulletin of the Polish Academy of Sciences. Technical Sciences; 2012, 60, 3; 495-505
    0239-7528
    Pojawia się w:
    Bulletin of the Polish Academy of Sciences. Technical Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Applying crystallography in analysis of trabecular bone backscatter
    Autorzy:
    Wojcik, J.
    Litniewski, J.
    Nowicki, A.
    Gambin, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/332506.pdf
    Data publikacji:
    2011
    Wydawca:
    Polskie Towarzystwo Akustyczne
    Opis:
    Some important details of the Backscatter Effective Cross-Sections obtained for random scattering structures (like trabecular bone) are explain by comparison with the results obtained by means of the simplified theoretical model. The simplified model was (establish) and justified on the basis of the structural analysis of the results obtained for exact model of the field scattering on complex structures. The simplified model is commonly used in description of the scattering on the regular structures like crystal. Comparison with experimental results for the trabecular bone is also presented. The results allowed to conclude that crystallographic methods could be potentially useful for extracting characteristic features of trabecular bone.
    Źródło:
    Hydroacoustics; 2011, 14; 255-266
    1642-1817
    Pojawia się w:
    Hydroacoustics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-8 z 8

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