- Tytuł:
- Structural and biological characteristics of self-organising chitosan hydrogels
- Autorzy:
-
Pieklarz, Katarzyna
Tylman, Michał
Modrzejewska, Zofia
Galita, Grzegorz
Majsterek, Ireneusz - Powiązania:
- https://bibliotekanauki.pl/articles/2131528.pdf
- Data publikacji:
- 2021
- Wydawca:
- Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
- Tematy:
-
biomaterials
chitosan
cytotoxicity
self-organising hydrogels
structural properties
tissue engineering - Opis:
- Creating innovative methods of treatment and regeneration of damaged tissues or organs is a key challenge of the twenty-first century. The aim of this study was to determine the possibility of producing and characterising the properties of self-organising chitosan hydrogels prepared with the use of chitosan lactate/chloride and disodium hydrogen phosphate dodecahydrate as a cross-linking agent. The structure and supramolecular architecture of the biomaterials were evaluated by Fourier-transform infrared spectroscopy and polarised optical microscopy. Biological studies assessed cytotoxicity by contact with a human colon adenocarcinoma cell line. The colourimetric resazurin assay showed that the obtained chitosan hydrogels are non-cytotoxic materials. Thus, self-organising biomaterials hold great promise for application in tissue engineering.
- Źródło:
-
Progress on Chemistry and Application of Chitin and its Derivatives; 2021, 26; 191-199
1896-5644 - Pojawia się w:
- Progress on Chemistry and Application of Chitin and its Derivatives
- Dostawca treści:
- Biblioteka Nauki
Artykuł