Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Yкраїнський (UK)
Przejdź do strony domowej biblioteki Centralna Biblioteka Wojskowa Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaCentralna Biblioteka Wojskowa

Wyszukujesz frazę "Gajewska, Beata" wg kryterium: Autor

  Lista filtrów
Wyrównaj
    Wyświetlanie 1-2 z 2
    Tytuł:
    Arginase isoenzymes in human cirrhotic liver
    Autorzy:
    Chrzanowska, Alicja
    Gajewska, Beata
    Barańczyk-Kuźma, Anna
    Powiązania:
    https://bibliotekanauki.pl/articles/1040542.pdf
    Data publikacji:
    2009
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    arginase activity
    liver cirrhosis
    isoenzyme expression
    Opis:
    Cirrhosis leads to an inability of the liver to perform its biochemical functions. It can also lead to hepatocellular carcinoma in which, as we showed lately, arginase isoenzyme pattern changes. The present work presents our results on arginase isoenzymes and their possible role in liver cirrhosis. The study was performed on tissues obtained during liver transplantation from 60 patients with liver cirrhosis, and on samples of histologically normal liver (control) from 40 patients with benign or colorectal cancer liver metastases removed during surgery, 6-7 cm from the tumor border. Arginase isoenzymes AI (so-called liver-type arginase) and AII (called extrahepatic arginase) were identified by Western blotting and isolated by ion-exchange chromatography. Their expression on mRNA level was studied by RT-PCR. A significant decrease in arginase activity, dependent of the liver clinical stage, was observed in cirrhotic tissue. Arginase AI activity and its mRNA level were significantly decreased in cirrhotic liver, whereas the activity and expression of arginase AII were concurrently raised, as compared to normal liver. Since arginase AI is a key enzyme of the urea cycle, whereas arginase AII most probably takes part in the biosynthesis of ornithine and polyamines, the defective ammonia inactivation and increased collagen biosynthesis observed in cirrhotic liver may be related to the changes in arginase AI and AII levels, respectively.
    Źródło:
    Acta Biochimica Polonica; 2009, 56, 3; 465-469
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Psychometric properties of the Polish version of the Generalized Anxiety Disorder Scale (GAD-7) in a non-clinical sample of employees during pandemic crisis
    Autorzy:
    Basińska, Beata A.
    Kwissa-Gajewska, Zuzanna
    Powiązania:
    https://bibliotekanauki.pl/articles/21375403.pdf
    Data publikacji:
    2023-11-13
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    anxiety
    measurement invariance
    pandemics
    Generalized Anxiety Disorder 7-item scale
    multigroup confirmatory factor analysis
    employee wellbeing
    Opis:
    Objectives The COVID-19 outbreak is an example of a crisis that triggered an increase in generalized anxiety disorder. The study aims to validate the Polish version of the Generalized Anxiety Disorder 7-item scale (GAD-7) by Spitzer et al. among a non-clinical sample of employees and examine the invariance depending on the gender and age of working adults. Material and Methods For assessing factor structure of the Polish version of the GAD-7, the data were collected from a sample of 821 adults employed in 4 economic sectors (health care, education, IT, public administration) during the initial phase of the COVID-19 pandemic in Poland (April 10–May 24, 2020). Due to differences in the severity of GAD symptoms across gender and age groups, the measurement invariance in these groups was tested. Results The results of a series of confirmatory factor analyses confirmed the unidimensionality of the GAD-7. The values of the composite reliability index and Cronbach’s α showed that it is a reliable tool. The GAD levels demonstrated strong relationships with professional burnout, psychological distress, and psychological complaints. These relationships were stronger than the relationships between these factors and job satisfaction. Construct, metric and scalar invariance across gender and age groups were documented. Women experienced more severe symptoms of generalized anxiety disorder than men. Generalized anxiety disorder affected 28% of respondents. Conclusions This study contributes evidence of the validation of the GAD among employees and also confirms the invariance depending on gender and age. The Polish version of the GAD-7 has good psychometric properties in a group of professionals and can be recommended for research and to be used in an occupational medicine practice, especially during crisis periods associated with the risk of developing a generalized anxiety disorder.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2023, 36, 4; 493-504
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-2 z 2

      Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies