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    Wyświetlanie 1-9 z 9
    Tytuł:
    IgM multiple myeloma: diagnostic difficulties and results of bortezomib treatment – case report
    Autorzy:
    Machowicz, Rafał
    Skwierawska, Kamila
    Mądry, Krzysztof
    Górka, Michał
    Żurawska, Jagoda
    Kacprzyk, Piotr
    Waszczuk-Gajda, Anna
    Dwilewicz-Trojaczek, Jadwiga
    Powiązania:
    https://bibliotekanauki.pl/articles/773502.pdf
    Data publikacji:
    2014
    Wydawca:
    Medical Education
    Tematy:
    IgM
    Waldenström’s macroglobulinemia
    bortezomib
    multiple myeloma
    Opis:
    The IgM paraprotein secretion is most frequently associated with Waldenström’s macroglobulinemia. In very rare cases it may also occur in multiple myeloma. The diagnostic and therapeutic process of a 84 year old male suffering from IgM multiple myeloma is described, including difficulties in establishing this diagnosis. Due to infectious complications, after the first cycle of melphalan– prednisone–bortezomib treatment, melphalan was stopped, subsequently, bortezomib and prednisone doses were also reduced. Two treatment interruptions have occurred. Despite reduced treatment intensity, the patient was in very good partial remission, while the toxicity profile was acceptable. IgM multiple myeloma should be included in the differential diagnosis of IgM paraproteinemia, also when osteolytic lesions and translocation 11:14 are not detected. Bortezomib-based therapy can be effective in elderly patients (also in those suffering from cardiac insufficiency), even when dose reduction is required.
    Źródło:
    OncoReview; 2014, 4, 4; A160-A164
    2450-6125
    Pojawia się w:
    OncoReview
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Attempts to Modify Austenitic Steel with Carbon Nanotubes
    Autorzy:
    Górka, Jacek
    Kik, Tomasz
    Burda, Michal
    Powiązania:
    https://bibliotekanauki.pl/articles/2048816.pdf
    Data publikacji:
    2022
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    multiwalled carbon nanotubes
    carburizer
    austenitic steel
    TIG remelting
    structure modification
    Opis:
    In this work, research on influence of multiwalled carbon nanotubes (MWCNTs), produced in Catalic Chemical Carbon Vapor Deposition, NANOCYLTM NC7000CNTs on a structure and properties of AISI 301 steel remelted by TIG arc. In the assessment of influence a type of carbon on properties and structure of austenitic steel, as a carbon filler was use also carburizer. In the specimens (AISI 301 plates) with dimensions 155×60×7 [mm] were drilled holes with 1.3 mm diameter and placed 0.5 mm under specimen surface. Next, to the drilled holes was implemented CNTs, carburizer and mixture of these both powders. Prepared specimens were remelted by TIG method on the CASTOTIG 2200 power source with 2.4 mm tungsten thoriated electrode with parameters sets for obtain 3.0 mm penetration depth. Remelted specimens were cut into the half of the welds distance and prepared for metallographic examinations. Cross sections of the specimens were tested on classical metallography microscopes, hardness tests, SEM analyses (on JEOL 5800 LV SEM EDX equipment) and phase identification by X-ray phase analysis on Philips APD X’Pert PW 3020 diffractometer. Hardness analysis indicates about 25% increase of hardness in the remelted area when the CTNs are used. In the specimens with carburizer there is no significant changes. SEM analyses of remelted areas on AISI 301 specimens modificated with CNTs, indicates that dark areas, initially interpret as one of the phase (based on optical microscope) is finally densely packed bladders with dimensions from 50 nm up to a few µm. These bladders are not present in the specimens with carburizer filler. High resolution scanning microscopy allow to observe in the this area protruding, longitudinal particles with 100-300 nm length. For identification of this phase, X-ray analysis was done. But very small dimensions of used CNTs (diameters about 9,5 nm), random orientation and small weight amount can make difficult or impossible to CNTs detection during XRD tests. It means that it is not possible to clearly determine nature of particles filling the cavities, it is only possible to suppose that they are CNTs beams with nanoparticles comes from their disintegration. Results of the researches indicates, that fill in the weld pool with different form of carbon (CNTs and carburizer) it is possible to achieve remelted beads with different structure and hardness distribution. It confirms validity of the research continuation with CNTs as a modifier of steels and also other metals and theirs alloys.
    Źródło:
    Archives of Metallurgy and Materials; 2022, 67, 1; 349-356
    1733-3490
    Pojawia się w:
    Archives of Metallurgy and Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The use of D2RQ in the integration of development tools
    Wykorzystanie D2RQ w integracji narzędzi rozwojowych
    Autorzy:
    Górka, Wojciech
    Socha, Michał
    Piasecki, Adam
    Powiązania:
    https://bibliotekanauki.pl/articles/587493.pdf
    Data publikacji:
    2016
    Wydawca:
    Uniwersytet Ekonomiczny w Katowicach
    Tematy:
    D2RQ
    Development tools
    Semantic integration
    Semantic web
    Narzędzia
    Semantyczna integracja
    Semantyczna sieć
    Opis:
    The aim of the article is to present an approach to the integration of heterogeneous data sets from independent computer systems. The article presents the use of integration by means of the virtualization of data sets in a consistent semantic graph. The integration was carried out in accordance with the ATOM methodology, which had been worked out earlier, using the D2QR tool. The tool is presented in the paper as a representative of a class of tools for integrating multiple heterogeneous data sources into one coherent data space. The article describes the experience of using the various options of D2RQ for integration of data sources and different approaches to the issues related to semantic integration. The authors also presented their modification of the tool and suggestions for its improvement. The research and experience are directly related to the CCMODE project (Common Criteria compliant Modular Open IT security Development Environment).
    Artykuł opisuje doświadczenia związane z realizacją semantycznej integracji systemów informatycznych. Prezentuje wykorzystanie integracji w rozumieniu wirtualizacji zbiorów danych w spójny graf semantyczny. Integracja została zrealizowana zgodnie z wypracowaną wcześniej metodyką ATOM, z wykorzystaniem narzędzia D2RQ. W artykule zostało przedstawione omawiane narzędzie jako reprezentant klasy narzędzi służących do integracji wielu źródeł danych w jedną spójną przestrzeń danych. Ponadto zostały opisane doświadczenia z wykorzystania poszczególnych możliwości D2RQ pod kątem integracji źródeł danych oraz różne sposoby podejścia do zagadnień związanych z tym tematem. Autorzy przedstawili również swoje modyfikacje narzędzia oraz propozycje jego udoskonalenia. Przeprowadzone badania i zebrane doświadczenia były bezpośrednio związane z realizacją projektu CCMODE (Common Criteria compliant Modular Open IT security Development Environment).
    Źródło:
    Studia Ekonomiczne; 2016, 308; 62-73
    2083-8611
    Pojawia się w:
    Studia Ekonomiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Fuzzy approach to device localization based on wireless network signal strength
    Rozmyte podejście do lokalizacji urządzeń na podstawie siły sygnału sieci bezprzewodowych
    Autorzy:
    Socha, Michał
    Górka, Wojciech
    Michalak, Marcin
    Powiązania:
    https://bibliotekanauki.pl/articles/2033299.pdf
    Data publikacji:
    2021
    Wydawca:
    Politechnika Lubelska. Wydawnictwo Politechniki Lubelskiej
    Tematy:
    wireless networks
    fuzzy sets
    device location
    sieci bezprzewodowe
    zbiory rozmyte
    lokalizowanie urządzeń
    Opis:
    The paper presents an original approach to device location detection in a building. The new method is based on a map of individual interiors, drawn up based on the measurements of the strength of wireless network signals for each building venue. The device is initially assigned to all venues whose descriptions sufficiently correspond with the current measurements taken by the device. A fuzzy assignment level for each of the potentially considered venues depends on the difference between the averaged network strengths for the venue and the signal strengths currently measured with the device for localization purposes. Ultimately, the device is assigned to the venue with the highest level of assignment.
    W pracy przedstawiono oryginalną metodę lokalizowania urządzeń w budynku. Nowa metoda bazuje na mapie poszczególnych pomieszczeń, stworzonej w oparciu o pomiary sygnałów sieci bezprzewodowych zmierzonych w tych pomieszczeniach. Wstępnie urządzenie przypisywane jest do tych pomieszczeń, których opis w odpowiednim stopniu pokrywa się z pomiarami dokonanymi przez urządzenie. Stopień rozmytej przynależności do każdego z wstępnie wytypowanych pomieszczeń zależy z kolei od różnicy pomiędzy uśrednionymi wartościami sygnałów sieci bezprzewodowych i aktualnie zmierzonymi do celów lokalizacji. Ostatecznie urządzeniu przypisywane jest to pomieszczenie, dla którego stopień przynależności jest największy.
    Źródło:
    Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska; 2021, 11, 2; 14-21
    2083-0157
    2391-6761
    Pojawia się w:
    Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    OPENArt - a Tool Supporting Education in the Field of Culture and Art
    Autorzy:
    Piasecki, Adam
    Socha, Michał
    Górka, Wojciech
    Jankowska, Anna
    Powiązania:
    https://bibliotekanauki.pl/articles/425936.pdf
    Data publikacji:
    2018
    Wydawca:
    Szkoła Główna Handlowa w Warszawie
    Tematy:
    universal design
    audio description
    modern art
    museum
    mobile applications
    Opis:
    Many museums in Poland and all over the world make use of mobile technologies. Unfortunately, neither Polish nor overseas applications offer universal solutions for users with different levels of knowledge and different disabilities. People with sight and hearing disabilities, as well as those physically handicapped, are very often culturally excluded, which means they are excluded from an important aspect of social life. As part of the project ‘OPENArt – Contemporary Art for All,’ a multimedia guide was developed in the form of an application for portable devices. It was designed in accordance with the participatory design methodology and principles of universal design. It facilitates access to works of art exposed to people with hearing and visual impairments. The application can be used to educate the blind, visually impaired, the deaf and hard of hearing, as well as people working with non-disabled children in arts and language classes. In the paper the innovative features of the guide were presented, and its educational values were characterized.
    Źródło:
    e-mentor. Czasopismo naukowe Szkoły Głównej Handlowej w Warszawie; 2018, 5 (77); 53-59
    1731-6758
    1731-7428
    Pojawia się w:
    e-mentor. Czasopismo naukowe Szkoły Głównej Handlowej w Warszawie
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    LEISURE TIME ACTIVITIES AMONG YOUNG PEOPLE AGED 13-16 FROM KOSOVO, BULGARIA AND POLAND
    Autorzy:
    Glapa, Agata
    Bronikowski, Michał
    Górka, Jowita
    Morina, Besnik
    Powiązania:
    https://bibliotekanauki.pl/articles/449233.pdf
    Data publikacji:
    2013
    Wydawca:
    Politechnika Opolska. Wydział Wychowania Fizycznego i Fizjoterapii
    Tematy:
    lifestyle
    youth
    physical activity
    socio-cultural factors
    Polska
    Bulgaria
    Kosovo
    Opis:
    This paper presents the results of the research on the physical activity of school youth in three European countries (Poland, Bulgaria, Kosovo) which are at different stages of socio-economic development and, therefore, of different possibilities and conditions in terms of leisure and mobility. The purpose of this cognitive study was to diagnose certain aspects of the lifestyle of young people aged 13-16 from Kosovo, Bulgaria and Poland, with a particular focus on physical activity. The practical aim, however, was an indication of such actions, arising from past experience that would aim at improving lifestyle, and could lead to the elimination or prevention of certain causes of physical inactivity by the youth of the countries surveyed. The research was conducted by the use of a diagnostic survey of a group of 524 people aged 13-16, among whom there were 88 people from Bulgaria, 136 people from Poland and 300 people from Kosovo. The research material was collected in 2012. The research that was carried out shows that the level of wealth (not so much of the family, but of the specific country) may have an impact on the choice of activities chosen by the youth. Undoubtedly socio-cultural factors and the tradition of social life, which impose certain ways of spending leisure time (as can be seen particularly in the case of the Bulgarian and Kosovar youth) are also of great importance. The above observations, taking into account local conditions, should be the starting point for all those who plan to introduce changes in the physical education systems in each of these countries in the future.
    Źródło:
    Journal of Physical Education & Health - Social Perspective; 2013, 2, 4; 33-42
    2084-7971
    Pojawia się w:
    Journal of Physical Education & Health - Social Perspective
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Deaf-friendly research - conducting research using an electronic questionnaire
    Autorzy:
    Irasiak, Anna
    Sroka, Elżbieta
    Górka, Wojciech
    Socha, Michał
    Piasecki, Adam
    Powiązania:
    https://bibliotekanauki.pl/articles/1927550.pdf
    Data publikacji:
    2021-12-22
    Wydawca:
    Szkoła Główna Handlowa w Warszawie
    Tematy:
    electronic questionnaire
    Deaf-friendly research
    universal user-oriented design
    surveys
    Avatar project
    Opis:
    A non-exclusive approach in conducting survey-based research which assumes the participation of people with disabilities is one of the important ethical aspects of the research process. The use of the tool, which has been designed in accordance with the universal user-oriented design, makes it possible for people with disabilities to take an active part in surveys. This means that they can present their attitudes and express opinions within the conducted surveys. The aim of the article is to present the issue of conducting surveys using an electronic questionnaire among deaf people, modelled on the Avatar PJM project. People with a hearing impairment, whose first or primary language used for communication is a sign language, should be given a questionnaire in an appropriate form enabling them to complete it easily. The discussed project presents a proposal to construct a questionnaire using the LimeSurvey software. The questionnaire has been adapted to the needs and expectations of the recipient group. The presented solution for designing a user-friendly research tool can be used in other types of research in this group of respondents (e.g. industrial or educational research) or can become an inspiration for further research in this field.
    Źródło:
    e-mentor. Czasopismo naukowe Szkoły Głównej Handlowej w Warszawie; 2021, 92, 5; 4-15
    1731-6758
    1731-7428
    Pojawia się w:
    e-mentor. Czasopismo naukowe Szkoły Głównej Handlowej w Warszawie
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    [Tłum.] Tomasz z Akwinu, "Kwestie dyskutowane o złu" (Quaestiones disputatae de malo), q. 16, a. 1
    [Transl.] Thomas Aquinas, "On evil" (Quaestiones disputate de malo q. 16, a. 1)
    Autorzy:
    Górka, Kinga
    Kaliszewska, Julia
    Ryglewicz, Eliza
    Waśniewska, Martyna
    Zembrzuski, Michał
    Powiązania:
    https://bibliotekanauki.pl/articles/452728.pdf
    Data publikacji:
    2012
    Wydawca:
    Naukowe Towarzystwo Tomistyczne
    Źródło:
    Rocznik Tomistyczny; 2012, 1; 229-248
    2300-1976
    Pojawia się w:
    Rocznik Tomistyczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Disruption of Trichoderma reesei gene encoding protein O-mannosyltransferase I results in a decrease of the enzyme activity and alteration of cell wall composition
    Autorzy:
    Górka-Nieć, Wioletta
    Pniewski, Michał
    Kania, Anna
    Perlińska-Lenart, Urszula
    Palamarczyk, Grażyna
    Kruszewska, Joanna
    Powiązania:
    https://bibliotekanauki.pl/articles/1040737.pdf
    Data publikacji:
    2008
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    Trichoderma reesei
    pmt1 gene disruption
    protein glycosylation
    cell wall composition
    Opis:
    In fungi transfer of the first mannosyl residue to proteins during their O-glycosylation is catalyzed by protein O-mannosyltransferases encoded by pmt genes. Disruption of the pmt1 gene in Trichoderma caused a significant decrease in the total activity of protein O-mannosyltransferases. Moreover, disruption of the pmt1 gene also led to osmotic sensitivity of the strain, indicating an essential role of the PMTI protein activity for cell wall synthesis. At the same time, the strain was defective in septa formation, producing only half the number of septa per unit length of hypha compared with the wild type. Disruption of the pmt1 gene decreased protein secretion but had no effect on glycosylation of secreted proteins, which suggests that PMTI protein O-mannosyltranferase does not take part in glycosylation of these proteins.
    Źródło:
    Acta Biochimica Polonica; 2008, 55, 2; 251-259
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-9 z 9

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