Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Yкраїнський (UK)
Przejdź do strony domowej biblioteki Centralna Biblioteka Wojskowa Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaCentralna Biblioteka Wojskowa

Wyszukujesz frazę "Florek, S." wg kryterium: Autor

  Lista filtrów
Wyrównaj
    Wyświetlanie 1-14 z 14
    Tytuł:
    Evaluation of the quality of life of older people with diabetes
    Autorzy:
    Wróblewska, Z.
    Chmielewski, J.P.
    Wojciechowska, M.
    Florek-Łuszczki, M.
    Wójcik, T.
    Hlinková, S.
    Wróblewska, I.
    Powiązania:
    https://bibliotekanauki.pl/articles/28763038.pdf
    Data publikacji:
    2023
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2023, 30, 3; 505-512
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Inequalities in breast cancer incidence and stage distribution between urban and rural female population in Swietokrzyskie Province, Poland
    Autorzy:
    Paszko, A.
    Krzyżak, M.J.
    Charkiewicz, A.E.
    Ziembicka, D.
    Żendzian-Piotrowska, M.
    Szpak, A.S.
    Florek-Łuszczki, M.
    Maślach, D.
    Powiązania:
    https://bibliotekanauki.pl/articles/2082946.pdf
    Data publikacji:
    2019
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    breast cancer
    incidence
    inequalities in health
    urban and rural population
    stage distribution
    Opis:
    Introduction and objective. One of the main factors determining the burden of breast cancer is the effectiveness of measures taken to combat this cancer including urban-rural differences. The aim of the study was to analyse the differences in breast cancer incidence and disease stage distribution among urban and rural women in the Świętokrzyskie Province as a part of a strategy for breast cancer control. Materials and method. The study of disease stage distribution included 483 female residents of Świętokrzyskie Province who were diagnosed in 2013 with invasive breast cancer, and reported to Świętokrzyskie Office for Cancer Registration. Urban-rural differences in breast cancer incidence in 2002–2013 were presented using Range Ratio (RR). Changes in incidence trends in urban and rural areas were analysed using joinpoint models. Annual Percentage Change (APC) of the rates was calculated for each time trend. Results. Breast cancer incidence rate in the urban female population was higher than in rural women with RR, amounting to 1.43. However, the analysis of trends showed that the pace and direction of change were developing negatively among inhabitants of rural areas. In 2002–2013, in rural women, the age-standardized rate (ASR) values increased by 2.8% per year (p<0.05). The course of ASR trends showed statistically significant urban-rural differences (p=0.004). Analysis of urban-rural differences in disease stage distribution revealed a non-significantly higher proportion of cases with localised stage in urban than in rural areas, amounting to 51.0% and 43.9%, respectively. Conclusions. Existing health inequalities indicate the need to intensify activities in rural areas and should be the starting point for making key decisions in combating breast cancer.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2019, 26, 1; 169-164
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Satisfaction with interpersonal relations among employees of State Forests in Poland
    Autorzy:
    Lachowski, S.
    Florek-Luszczki, M.
    Zagórski, J.
    Lachowska, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/2081659.pdf
    Data publikacji:
    2018
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    job satisfaction
    interpersonal relationships
    forestry workers
    determinants of satisfaction
    Opis:
    Introduction and objective. The aim of this study is to assess the interpersonal relations of employees of State Forests in Poland, as well as to indicate the factors related to the level of satisfaction with the relations among people employed in similar positions, and relations with superiors. Materials and method. The issues investigated were developed based on research conducted between 2014–2015 among employees of State Forests in Poland. In each of the 9 forest districts selected, 25 people were selected for testing from 3 groups of employees: foresters, deputy foresters and supervisors, together with administrative staff. Altogether, 399 people took part in the study conducted by means of a questionnaire. Results. The study showed that the overall level of satisfaction with interpersonal relations among employees of State Forests in Poland is high. Analysis indicated that the demographic characteristics of respondents, such as age, gender or place of residence, had no significant influence on satisfaction with interpersonal relations in the workplace. However, the level of satisfaction with interpersonal relations was positively affected by a high level of overall job satisfaction and satisfaction with remuneration. Decrease in the level of satisfaction was influenced by the accumulation of stressful life events and employment in administration. Conclusions. Satisfaction with interpersonal relationships in the workplace is an important indicator of employee mental health. Studies have shown the need to broaden the scope of research into the variables that determine the character and personality of an employee.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2018, 25, 2; 300-306
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Isobolographic assessment of interactions between retigabine and phenytoin in the mouse maximal electroshock-induced seizure model and chimney test
    Izobolograficzne oszacowanie interakcji pomiędzy retigabiną a fenytoiną w mysim modelu drgawek wywoływanych maksymalnym wstrząsem elektrycznym i teście komina
    Autorzy:
    Żółkowska, D.
    Zagaja, M.
    Miziak, B.
    Kondrat-Wróbel, M.W.
    Załuska, K.
    Florek-Łuszczki, M.
    Szpringer, M.
    Drop, B.
    Zadrożniak, M.
    Czuczwar, S.J.
    Łuszczki, J.J.
    Powiązania:
    https://bibliotekanauki.pl/articles/2052143.pdf
    Data publikacji:
    2016
    Wydawca:
    Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
    Tematy:
    drug interactions
    isobolographic analysis
    phenytoin
    retigabine
    interakcje lekowe
    analiza izobolograficzna
    fenytoina
    retigabina
    Opis:
    Background. Search for beneficial combinations of antiepileptic drugs (AEDs) that can be used in patients with pharmacoresistant epilepsy, is still conducted both empirically and rationally, based on molecular mechanisms of AEDs’ action. This study was aimed at characterizing the interaction profiles for the combination of two AEDs (i.e., retigabine [RTG] and phenytoin [PHT]) in the maximal electroshock-induced seizures (MES) and chimney test (motor performance) in adult male albino Swiss mice. Material and methods. Type I isobolographic analysis was used to determine interactions for the combination of RTG with PHT (at three fixed-ratios of 1:3, 1:1 and 3:1) with respect to its anticonvulsant and acute neurotoxic effects in the MES and chimney tests, respectively. Total brain concentrations of RTG and PHT were estimated to exclude any pharmacokinetic interaction between AEDs. Results. The combination of RTG with PHT at the fixed-ratios of 1:3, 1:1 and 3:1 produced additive interactions in both, the MES and chimney tests. RTG and PHT did not affect each other their total brain concentrations in mice, confirming pharmacodynamic interaction between the investigated drugs. Conclusions. The combination of RTG with PHT was neutral suggesting that this two-drug combination might occur favorable in some patients with refractory epilepsy.
    Wprowadzenie. Poszukiwanie korzystnych kombinacji leków przeciwpadaczkowych (LPP), które mogą być zastosowane u pacjentów z padaczką lekooporną, jest wciąż przeprowadzane zarówno empirycznie jak i racjonalnie, w oparciu o molekularne mechanizmy działania LPP. Celem badania było scharakteryzowanie profilów interakcji kombinacji dwóch leków (tj. retigabiny [RTG] i fenytoiny [PHT]) w teście drgawek wywoływanych maksymalnych wstrząsem elektrycznym (MES) i w teście komina (koordynacja ruchowa) u dorosłych samców myszy szczepu Albino Swiss. Materiał i metody. Typ I analizy izobolograficznej był zastosowany aby wyznaczyć typy interakcji dla kombinacji RTG z PHT (w trzech stałych proporcjach dawek 1:3, 1:1 i 3:1) w odniesieniu do jej działań przeciwdrgawkowych i ostrych działaniach niepożądanych (neurotoksycznych) odpowiednio w testach MES i komina. Całkowite stężenia mózgowe RTG i PHT były oceniane, aby wykluczyć interakcje farmakokinetyczną pomiędzy LPP. Wyniki. Wyniki wskazują, że kombinacja RTG z PHT w stałych proporcjach dawek 1:3, 1:1 i 3:1 wykazuje interakcje addytywne w obu testach MES i komina. RTG i PHT nie wpływały wzajemnie na swe całkowite stężenia mózgowe u myszy, potwierdzając interakcję farmakodynamiczną pomiędzy badanymi lekami. Wnioski. Przedkliniczny profil dla kombinacji RTG z PHT jest neutralny, sugerując, że ta dwulekowa kombinacja mogłaby okazać się korzystna u niektórych pacjentów z padaczką lekooporną.
    Źródło:
    Health Problems of Civilization; 2016, 10, 4; 54-59
    2353-6942
    2354-0265
    Pojawia się w:
    Health Problems of Civilization
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Searching for in vitro biomarkers of susceptibility to prostate and cervical cancers by analysis of chromosomal instability, gamma-H2AX foci, polymorphisms in DNA repair genes and apoptosis
    Autorzy:
    Wegierek-Ciuk, A.
    Arabski, M.
    Kedzierawski, P.
    Florek, A.
    Solowiej, D.
    Gozdz, S.
    Lisowska, H.
    Kowalik, A.
    Kowalska, M.
    Wojcik, A.
    Polanska, J.
    Lankoff, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/3629.pdf
    Data publikacji:
    2015
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    in vitro biomarker
    susceptibility
    prostate
    cervical cancer
    cancer
    patient
    human disease
    lymphocyte
    man
    ionizing radiation
    chromosome instability
    gamma-H2AX biomarker
    polymorphism
    DNA repair gene
    apoptosis
    Opis:
    Introduction and objective. According to the cancer epidemiology databases, cancer is the second leading cause of death in developing countries. Moreover, the WHO predicts a continuing increase in the incidence of cancer, extending this trend well into the next several decades. Hence, it seems obvious that the prediction of cancer susceptibility and early diagnosis is an important goal for modern biomedical sciences. The aim of this study is to clarify the value of chromosomal damage, capacity for the repair of double-strand breaks (DSBs), polymorphisms in DNA repair genes, and apoptosis as prognostic markers for prostate and cervical cancer. Materials and methods. 30 prostate cancer patients and 30 cervical cancer patients were enrolled into the study. In addition, 30 healthy female donors and 30 healthy male donors served as controls. The following endpoints were investigated: frequency of micronuclei, gamma-H2AX fluorescence, XRCC1 194C>T, XRCC1 399G>A, XRCC3 IVS5–14 A>G, OGG1 326 Ser>Cys polymorphisms and apoptosis. Results. Among all tested factors, only the homozygous variant (Arg/Arg) in XRCC1 (399 Arg/Gln) was strongly associated with prostate cancer risk, and only a low apoptotic response was connected with cervical cancer risk. The presented study confirmed a positive association between the frequency of MN and increased prostate and cervical cancer risk. However, such a biomarker is not cancer specific. In addition, the information gained by analyzing the gamma-H2AX fluorescence, as well apoptosis, had no value for predicting the risk of prostate and cervical cancers. Conclusions. The final conclusion of the study is that cancer susceptibility is a complex phenotype not readily detectable in relatively small studies by functional assays or analysis of SNP in few, selected genes.
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2015, 09, 2
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effect of N-(p-ethoxycarbonylphenylmethyl) -p-isopropoxyphenylsuccinimide on the anticonvulsant action of four classical antiepileptic drugs in the mouse maximal electroshock-induced seizure model
    Autorzy:
    Łuszczki, J.J.
    Marzeda, E.
    Kondrat-Wrobel, M.W.
    Wrobel, J.
    Kocharov, S.L.
    Florek-Luszczki, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/3266.pdf
    Data publikacji:
    2014
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    N-(p-ethoxycarbonylphenylmethyl) -p-isopropoxyphenylsuccinimide
    anticonvulsant action
    antiepileptic drug
    mice
    mouse
    electroshock-induced seizure model
    seizure
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2014, 08, 1
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Emotional attitudes of young people completing secondary schools towards genetic modification of organisms (GMO) and genetically modified foods (GMF)
    Autorzy:
    Jurkiewicz, A.
    Zagorski, J.
    Bujak, F.
    Lachowski, S.
    Florek-Luszczki, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/49559.pdf
    Data publikacji:
    2014
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2014, 21, 1
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Działania instytucjonalne na rzecz osób niepełnosprawnych
    Institutional actions on behalf of the disabled
    Autorzy:
    Florek-Luszczki, M.
    Lachowski, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/3795.pdf
    Data publikacji:
    2013
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    niepelnosprawnosc
    osoby niepelnosprawne
    system instytucjonalny
    wsparcie instytucjonalne
    Źródło:
    Medycyna Ogólna i Nauki o Zdrowiu; 2013, 19(48), 4
    2083-4543
    Pojawia się w:
    Medycyna Ogólna i Nauki o Zdrowiu
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    No effect of3-(N-p-isopropoxyphenylsuccinimidomethylamino)-cinnamic acid on anticonvulsant action of different classical antiepileptic drugs in mouse maximal electroshock-induced seizure model
    Autorzy:
    Luszczycki, J. J.
    Marczewski, T.
    Marzeda, E.
    Durmowicz, D.
    Podgorska, D.
    Kocharov, S. L.
    Florek-Luszczki, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/972739.pdf
    Data publikacji:
    2012
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    antiepileptic drugs
    maximal electroshock-induced seizures
    pharmacokinetic/pharmacodynamic interaction
    p-isopropoxyphenylsuccinimide derivative
    Opis:
    Introduction and objective: The aim of the study was to determine the effects of 3-(N-p-isopropoxyphenylsuccinimidomethylamino)-cinnamic acid (IPPSMA-CA – a new succinimide derivative) on the protective action of 4 classical antiepileptic drugs (AEDs): carbamazepine [CBZ], phenobarbital [PB], phenytoin [PHT] and valproate [VPA]), against maximal electroshock (MES)-induced tonic seizures in mice. Materials and methods: Tonic hind limb extension (seizure activity) was evoked in adult male albino Swiss mice by a current (sine-wave, 25 mA, 500 V, 50 Hz, 0.2 s stimulus duration) delivered via auricular electrodes. Acute adverse-effectprofiles of the combination of IPPSMA-CA and 4 classical AEDs (CBZ, PB, PHT and VPA) with respect to motor performance, long-term memory and skeletal muscular strength were measured in the chimney, passive avoidance and grip-strength tests, respectively. Results: IPPSMA-CA administered at 150 mg/kg (i.p.) significantly elevated the threshold for electroconvulsions in mice (p<0.01). IPPSMA-CA at doses of 50 and 100 mg/kg, however, had no significant impact on the threshold for electroconvulsions in mice. Nor did IPPSMA-CA (100 mg/kg) significantly affect the anticonvulsant activity of CBZ, PB, PHT and VPA in the MES test in mice. None of the examined combinations of IPPSMA-CA (100 mg/kg, i.p.) with CBZ, PB, PHT and VPA (at their ED50 values from the MES-induced seizure test) affected motor coordination in the chimney test, long-term memory in the passive avoidance task, and muscular strength in the grip-strength test in mice. This indicates no possible acute adverse effects in animals. Conclusions: IPPSMA-CA elevated the threshold for electroconvulsions in mice in a dose-dependent manner. However, IPPSMA-CA at a sub-protective dose of 100 mg/kg did not affect the anticonvulsant action of various classical AEDs in the mouse MES model. Thus, the combinations of IPPSMA-CA with CBZ, PB, PHT and VPA are neutral from a preclinical viewpoint.
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2012, 06, 1; 20-24
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Water Bound in Elytra of the Weevil Liparus glabrirostris (Küster, 1849) by NMR and Sorption Isotherm (Coleoptera: Curculionidae)
    Autorzy:
    Harańczyk, H.
    Florek, M.
    Nowak, P.
    Knutelski, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/1490163.pdf
    Data publikacji:
    2012-02
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    82.56.Na
    Opis:
    Scanning electron microscopy micrograms of the elytra of Liparus glabrirostris showed a different dorsal and ventral surface and a multilayered inner structure. Hydration kinetics, sorption isotherm, and proton free induction decays are measured for hydrated elytra of the weevil species Liparus glabrirostris (Coleoptera: Curculionidae) in the atmosphere with controlled humidity. Very tightly bound water fraction with the mass Δ m/$m_0$ = 0.037 ± 0.004, and very short hydration time, tightly bound water Δ m/$m_0$ = 0.034 ± 0.009, and hydration time $t_1^{h}$ = (3.31 ± 0.93) h, and finally loosely bound water fraction with $t_2^{h}$ = (25.5 ± 7.8) h were distinguished. The sorption isotherm is sigmoidal in form, with the mass of water saturating primary water binding sites equal of Δ M/$m_0$ = 0.036. The proton free induction decays show the presence of solid signal (well fitted by a Gaussian function) from elytra ($T_{2G}$* ≈ 18 μs), the immobilized water fraction ($T_{2L_1}$* ≈ 120 μs) and mobile water pool ($T_{2 L_2}$* ≈ 300 μs). The hydration dependence of the water bound in elytra of L. glabrirostris, L/S is linear showing the absence of water-soluble solid fraction and negligible content of water pool "sealed" in pores of the structure.
    Źródło:
    Acta Physica Polonica A; 2012, 121, 2; 491-496
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Application of Algebraic Combinatorics to Finite Spin Systems with Dihedral Symmetry
    Autorzy:
    Bucikiewicz, S.
    Dębski, L.
    Florek, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/2028876.pdf
    Data publikacji:
    2001-10
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    02.20.Bb
    75.10.Jm
    75.75.+a
    Opis:
    Properties of a given symmetry group G are very important in investigation of a physical system invariant under its action. In the case of finite spin systems (magnetic rings as Fe$\text{}_{6}$, Cu$\text{}_{6}$, Fe$\text{}_{10}$, some planar macromolecules as Fe$\text{}_{12}$ or Fe$\text{}_{8}$) the symmetry group is isomorphic with the dihedral group D$\text{}_{N}$. In this paper group-theoretical "parameters" of such groups are determined, especially decompositions of transitive representations into irreducible ones and double cosets. These results are necessary to construct matrix elements of any operator commuting with G in an efficient way. The approach proposed can be useful in many branches of physics, but here it is applied to finite spin systems, which serve as models for mesoscopic magnets.
    Źródło:
    Acta Physica Polonica A; 2001, 100, 4; 453-475
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ocena przydatności żywieniowej kiszonek z traw w opasie młodego bydła
    Assessment of feeding value of grass silage in fattening of young cattle
    Autorzy:
    Sobieraj, A.
    Purwin, C.
    Florek, S.
    Stanek, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/802664.pdf
    Data publikacji:
    2001
    Wydawca:
    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie. Wydawnictwo Szkoły Głównej Gospodarstwa Wiejskiego w Warszawie
    Źródło:
    Zeszyty Problemowe Postępów Nauk Rolniczych; 2001, 479
    0084-5477
    Pojawia się w:
    Zeszyty Problemowe Postępów Nauk Rolniczych
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-14 z 14

      Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies