Autor: Dembinska-Kiec, Aldona - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Relation of the protein glycation, oxidation and nitration to the osteocalcin level in obese subjects
Autorzy:: Razny, Urszula
Goralska, Joanna
Zdzienicka, Anna
Fedak, Danuta
Masania, Jinit
Rabbani, Naila
Thornalley, Paul
Pawlica-Gosiewska, Dorota
Gawlik, Katarzyna
Dembinska-Kiec, Aldona
Solnica, Bogdan
Malczewska-Malec, Malgorzata
Powiązania:: https://bibliotekanauki.pl/articles/1038577.pdf
Data publikacji:: 2017
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: advanced glycation end products
oxidative stress
obesity
osteocalcin
Opis:: Carboxylated osteocalcin (Gla-OC) contributes to the bone formation, whereas its undercarboxylated form (Glu-OC) takes part in the energy metabolism. In vitro studies had shown that treatment of osteoblast-like cells with advanced glycation end product-modified bovine serum resulted in reduced synthesis of collagen 1 and osteocalcin. The aim of this study was to find association between Gla-OC and markers of protein glycation, oxidation and nitration, as well as pro-inflammatory and antioxidant defense markers in obese subjects. Non-obese [(body mass index (BMI)<30 kg/m; n=34)] and obese subjects (30
Źródło:: Acta Biochimica Polonica; 2017, 64, 3; 415-422
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Modulation of the human preadipocyte mitochondrial activity by beta-carotene
Autorzy:: Śliwa, Agnieszka
Góralska, Joanna
Czech, Urszula
Gruca, Anna
Polus, Anna
Zapała, Barbara
Dembińska-Kieć, Aldona
Powiązania:: https://bibliotekanauki.pl/articles/1039768.pdf
Data publikacji:: 2012
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: oxidative phosphorylation
preadipocytes
mitochondria
beta-carotene
Opis:: Increased ROS generation by the overload by metabolic substrates mitochondria paralleled by decrease of antioxidant activity are typical events found in metabolic syndrome and diabetes type 2. Metabolites of beta-carotene (BC) such as retinoic acid (RA), as well as low concentration of reactive oxygen species (ROS) modify the mitochondrial bioenergetic function. The aim of the study was to investigate the effect of beta-carotene on mitochondrial activity in human preadipocytes. BC used in concentrations, 10 or 30 µM, decreased mitochondrial membrane potential, inhibited mitochondrial respiration and decreased cellular ATP content. We conclude, that BC, the known antioxidant may decrease oxidative phosphorylation capacity of mitochondria.
Źródło:: Acta Biochimica Polonica; 2012, 59, 1; 39-41
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Ligands of peroxisome proliferator-activated receptor-γ increase the generation of vascular endothelial growth factor in vascular smooth muscle cells and in macrophages.
Autorzy:: Jozkowicz, Alicja
Dulak, Jozef
Piatkowska, Ewa
Placha, Wojciech
Dembinska-Kiec, Aldona
Powiązania:: https://bibliotekanauki.pl/articles/1044268.pdf
Data publikacji:: 2000
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: angiogenesis
ciglitazone
vascular endothelial growth factor
thiazolidinediones
prostaglandin-J2
peroxisome proliferator-activated receptor-γ
Opis:: Peroxisome proliferator-activated receptors-γ (PPARγ) are ligand-inducible transcription factors of the nuclear hormone receptor superfamily. We examined the effect of PPARγ activation on the generation of vascular endothelial growth factor (VEGF), one of the major angiogenic agents. Rat vascular smooth muscle cells (VSMC) and murine macrophages RAW264.7 were incubated for 24 h with PPARγ activators: prostaglandin J2 and ciglitazone. PPARγ were expressed in VSMC and RAW cells and their activity was upregulated in the presence of PGJ2 and ciglitazone. Incubation of the cells with PPARγ activators significantly augmented the release of VEGF protein into the media, both in resting and in IL-1β- or LPS-stimulated cultures. The higher protein generation was connected with the increased expression of mRNA and transcriptional activation of VEGF promoter. We conclude that the activation of PPARγ upregulates the generation of VEGF and may be involved in the regulation of angiogenesis.
Źródło:: Acta Biochimica Polonica; 2000, 47, 4; 1147-1157
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Nitric oxide mediates the mitogenic effects of insulin and vascular endothelial growth factor but not of leptin in endothelial cells
Autorzy:: Józkowicz, Alicja
Pankiewicz, Joanna
Dulak, Józef
Partyka, Łukasz
Wybrańska, Iwona
Huk, Igor
Dembińska-Kieć, Aldona
Powiązania:: https://bibliotekanauki.pl/articles/1044482.pdf
Data publikacji:: 1999
Wydawca:: Polskie Towarzystwo Biochemiczne
Źródło:: Acta Biochimica Polonica; 1999, 46, 3; 703-715
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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