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    Wyświetlanie 1-3 z 3
    Tytuł:
    Abnormal FHIT gene transcript and c-myc and c-erbB2 amplification in breast cancer.
    Autorzy:
    Kowara, Renata
    Gołębiowski, Filip
    Chrzan, Paweł
    Skokowski, Jaroslaw
    Karmolinski, Andrzej
    Pawełczyk, Tadeusz
    Powiązania:
    https://bibliotekanauki.pl/articles/1043760.pdf
    Data publikacji:
    2002
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    amplification
    c-myc
    FHIT transcripts
    breast cancer
    c-erbB2
    Opis:
    Searching for ways to improve the characterization of breast cancer we examined the relationship between the status of the FHIT gene transcript and amplification of c-myc and the c-erbB2 oncogene. Abnormal FHIT transcript was detected in 32 of 79 cancers examined. The presence of Fhit protein estimated by Western blots was evident only in cancers exhibiting a normal-sized FHIT transcript. This indicates that abnormal FHIT transcripts observed in our study did not encode any Fhit protein or the amount of such protein was very low. There was no association between the presence of aberrant FHIT gene transcript with age, tumor size, estrogen and progesterone receptor status, local metastases and histological grading. However, the abnormalities in FHIT gene transcripts were observed with different frequency depending on the histopathological type of the tumor. The aberrant FHIT transcript was detected in 60% of lobular cancers and only in 28% of ductal cancers. Analyzing the occurrence of c-myc and c-erbB2 amplification and the presence of aberrant FHIT gene transcripts we found that the aberrant FHIT transcript more frequently occurred in tissues with c-myc amplification. There was a significant (P <0.05) correlation between the occurrence of the aberrant FHIT gene transcript with accompanying c-myc amplification and positive lymph node status. However, in order to evaluate the predictive value of these findings in breast cancer, an extended clinical follow up will be necessary.
    Źródło:
    Acta Biochimica Polonica; 2002, 49, 2; 341-350
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Etapy projektowania z wykorzystaniem nowoczesnych metod inżynierii odwrotnej
    Design stages using modern reverse engineering methods
    Autorzy:
    Czarnecki, Paweł
    Kawlewska, Edyta
    Sobota, Robert
    Burkacki, Michał
    Chrzan, Miłosz
    Powiązania:
    https://bibliotekanauki.pl/articles/21375451.pdf
    Data publikacji:
    2022
    Wydawca:
    Politechnika Śląska. Katedra Biomechatroniki
    Tematy:
    skanowanie 3D
    modele powierzchniowe
    modelowanie bryłowe
    druk 3D
    3D scanning
    surface models
    solid modeling
    3D printing
    Opis:
    W pracy zostały przedstawione i opisane kolejne etapy procesu projektowego, z zastosowaniem inżynierii odwrotnej – od akwizycji aż do wytworzenia prototypu. Model bryłowy opracowano w programie Geomagic Design X, na podstawie skanów 3D. Modele przygotowano również do druku z wykorzystaniem dwóch technologii – FDM i SLA. Dokonano również weryfikacji opracowanych modeli na podstawie porównania z wymiarami obiektu rzeczywistego oraz wydrukowanych prototypów.
    Design stages using modern reverse engineering methods Abstract: This work presents and describes the successive stages of the design process, with the use of reverse engineering - from acquisition to prototype production. The solid model was developed in the Geomagic Design X program, based on 3D scans. The models were also prepared for printing using two technologies - FDM and SLA. The developed models were eventually verified on the basis of comparison with the dimensions of the real object and printed prototypes.
    Źródło:
    Aktualne Problemy Biomechaniki; 2022, 22; 5-12
    1898-763X
    Pojawia się w:
    Aktualne Problemy Biomechaniki
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Transmission system model in the track-vehicle relationship based on Long Term Evolution technology
    Autorzy:
    Chrzan, Marcin
    Pirosz, Paweł
    Paś, Jacek
    Powiązania:
    https://bibliotekanauki.pl/articles/27311803.pdf
    Data publikacji:
    2023
    Wydawca:
    Polska Akademia Nauk. Czasopisma i Monografie PAN
    Tematy:
    rail traffic
    track vehicle
    safety
    telecommunications
    transport
    control
    operation
    ruch kolejowy
    pojazd szynowy
    bezpieczeństwo
    telekomunikacja
    kontrola
    operacja
    Opis:
    Because of degradations of the wired infrastructure connecting the element of railroad control systems, and related primarily to their destruction, the use of the radio transmission medium for independent management of railroad traffic control devices is increasingly being considered. An undoubted problem in implying such solutions is the security of transmission in such systems. It should be noted that security at a certain level of transmission is currently already offered by the radio transmission systems themselves, which has also been used in the GSM-R standard. The creation of a separate dedicated system for railroads involves huge expenditures for the design, testing, certification and, finally, construction and implementation of such technology. Therefore, in the opinion of the author of this dissertation, it is possible to use public open radio networks for the needs of railroads, which significantly reduces costs, since such a system is based on existing infrastructure. It is necessary to develop a way of transmitting information that meets the requirements of secure transmission in the sense of railroad traffic control systems. The task is to develop a general model for open radio transmission in traffic control systems based on the latest public radio standard, which is LTE, 5G or Future Railway Mobile Communications System (FRMCS). The article will present the concept of data transmission in the track–vehicle relationship with the use of LTE (Long Term Evolution) technology. It will show the concept of transmission based on the PN EN50159:2011 standard and the results of the tests conducted during control trips on the railway route. The main element that will be subject to the research will include the transmission safety and its delay. The impact of a type of transmission encryption on its delay will be estimated with the assumed blocks of data sent during the transmission. A probability distribution and density functions of the transmission delay probability distribution with the message sizes in the range from 16B to 10 kB with four ways of the signal encoding according to the PN-EN50159:2011 standard will be also analysed.
    Źródło:
    Archives of Transport; 2023, 66, 2; 89--108
    0866-9546
    2300-8830
    Pojawia się w:
    Archives of Transport
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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