Autor: Chmurzyński, J. - Katalog OPAC zbiorów

Tytuł:: Magiczne zachowania, dziwne strachy i lęki
Autorzy:: Chmurzynski, J.A.
Powiązania:: https://bibliotekanauki.pl/articles/855836.pdf
Data publikacji:: 2013
Wydawca:: Polskie Towarzystwo Przyrodników im. Kopernika
Tematy:: zachowanie sie czlowieka
zachowanie sie zwierzat
zachowania magiczne
przesady
lek
strach
Źródło:: Wszechświat; 2013, 114, 10-12
0043-9592
Pojawia się w:: Wszechświat
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Conformational analysis of fragment of human Pin1 ww domain: influence of charged amino-acid residues on β-hairpin structure
Autorzy:: Makowska, J.
Uber, D.
Żmudzińska, W.
Chmurzyński, L.
Powiązania:: https://bibliotekanauki.pl/articles/1935818.pdf
Data publikacji:: 2014
Wydawca:: Politechnika Gdańska
Tematy:: peptide conformation
β-hairpin
hPin1 protein
NMR
Opis:: We examined the effect of like-charged residues on the conformation of an original nine amino-acid-residue fragment of the human Pin1 WW domain (hPin1) with the following sequence: Ac-Arg-Met-Ser-Arg-Ser-Ser-Gly-Arg-Val-NH 2 (U9). This was facilitated by CD and NMR spectroscopic measurements, and molecular dynamics calculations. Our ear lier studies suggested that the presence of like-charged residues at the end of a short polypeptide chain composed of nonpolar residues could induce a chain reversal. For the U9 peptide, canonical MD simulations with NMR -derived restraints demonstrated the presence of ensembles of structures with a tendency to form a β -chain reversal. Additionally, thermal stabilities of the peptide under study were measured using differential scanning calorimetry ( DSC ). The estimated well defined phase transition point showed that conformational equilibria in the U9 peptide were strongly dependent on temperature.
Źródło:: TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk; 2014, 18, 4; 343--349
1428-6394
Pojawia się w:: TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 8.

Tytuł:: Właściwości antyoksydacyjne, antybakteryjne i przeciwgrzybicze związków kompleksowych miedzi(II)
Antioxidant, antibacterial and antifungal properties of complex compounds of copper(II)
Autorzy:: Piotrowska, A.
Drzeżdżon, J.
Jacewicz, D.
Chmurzyński, L.
Powiązania:: https://bibliotekanauki.pl/articles/171722.pdf
Data publikacji:: 2017
Wydawca:: Polskie Towarzystwo Chemiczne
Tematy:: związki kompleksowe
miedź(II)
antyoksydanty
aktywność antybakteryjna
aktywność przeciwgrzybicza
copper(II) complexes
antioxidants
antibacterial activity
antifungal activity
Opis:: Since late 1930s copper has been recognized as an essential trace metal in living organisms. Copper(II) cation plays the role as a coordination center not only in the single-nuclear complexes, but also in the multinuclear coordination compounds with a particular emphasis on the polymers as ligands. The selected complex compounds of copper(II) with ligands which are organic and inorganic species have been characterized taking into account their physico-chemical properties. In addition, the complex compounds containing ligands such as Schiff ’s bases, hydrocarbons, organic bases, and also polycarboxylic anions: oxydiacetate, thiodiacetate, iminodiacetate and dipicolinate have been described considering their role in the biological systems. Nowadays tested coordination compounds of copper(II) have interesting antibacterial activities against bacteria strains that are antagonistic to the human. The antibacterial activity of copper(II) complex is stronger than some of the known antibacterial substances e.g. ciprofloxacin. In addition, copper(II) complex compounds exhibit a 64-fold greater antimicrobial properties than copper(II) chloride. Moreover, these compounds have antifungal and antioxidant properties. The activities of antibacterial, antifungal, and antioxidant complex compounds of copper( II) have been compared to the reactivities of these compounds with complexes used as reference substances, e.g. L-ascorbic acid, in the assay using nitrotetrazolium blue.
Źródło:: Wiadomości Chemiczne; 2017, 71, 3-4; 219-240
0043-5104
2300-0295
Pojawia się w:: Wiadomości Chemiczne
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 9.

Tytuł:: Wybrane właściwości fizykochemiczne polikarboksylanowych związków kompleksowych kobaltu(II), niklu(II), miedzi(II) i oksowanadu(IV)
Selected physicochemical properties of polycarboxylate cobalt(II), nickel(II), copper(II) and oxidovanadium(IV) complex compounds
Autorzy:: Piotrowska-Kirschling, A.
Drzeżdżon, J.
Chmurzyński, L.
Jacewicz, D.
Powiązania:: https://bibliotekanauki.pl/articles/171735.pdf
Data publikacji:: 2018
Wydawca:: Polskie Towarzystwo Chemiczne
Tematy:: polikarboksylanowe związki kompleksowe
kinetyka
metoda stopped-flow
właściwości antyoksydacyjne
woltamperometria cykliczna
polycarboxylate complexes
kinetics
stopped-flow method
antioxidant activity
cyclic voltammetry
Opis:: Cobalt(II), nickel(II), copper(II) and oxidovanadium(IV) cations are coordination centers in many polycarboxylate complexes [1‒16]. A number of coordination compounds of transition metal ions with such ligands as polycarboxylate anions and heterocyclic organic ligands, e.g. 1,10-phenanthroline (phen) or 2,2’-bipyridine (bipy) have been examined for their biological properties [3‒16]. Their selected structures and physicochemical properties have been described in the first chapter. The polycarboxylate coordination compounds of cobalt(II), nickel(II), copper(II) and oxidovanadium(IV) have interesting antioxidant, antibacterial and antifungal activities. The antioxidant properties of polycarboxylate complexes of Co(II), Ni(II), Cu(II) and VO(IV) with 4-picoline, 1,10-phenanhroline and 2,2’-bipyridine have been investigated towards the superoxide anion radical using the nitro blue tetrazolium chloride (NBT) test and the cyclic voltammetry (CV). Their antibacterial and antifungal activities have been tested against bacteria and fungus strains that are antagonistic to the human. The determined biological properties of the oxydiacetate Co(II), Ni(II), VO(IV) complexes with bipy/phen, the thiodiacetate VO(IV) and the iminodiacetate Cu(II) complexes have been compared with these of L-ascorbic acid, which is chemical compounds commonly used as the reference antioxidant substance. Consequently, the comparison of antioxidant properties of selected cobalt( II), nickel(II), copper(II) and oxidovanadium(IV) polycarboxylate compounds is described in this work (Section 3, Tab. 1‒4). The kinetics of substitution reactions of selected copper(II) polycarboxylate complex compounds were monitored using the stopped-flow method in various reaction conditions (concentration of complex, temperature, solvent) (Rys. 5‒6) [5, 6]. The obtained results of the kinetic studies of the substitution reactions of [Cu(tda)]_n with 2,2’-bipyridine in aqueous surfactants solvents: sodium dodecyl sulfate (SDS_aq) and hexadecyl trimethyl- ammonium bromide (CTAB_aq) at 298.15 K (25 °C) are presented.
Źródło:: Wiadomości Chemiczne; 2018, 72, 11-12; 797-814
0043-5104
2300-0295
Pojawia się w:: Wiadomości Chemiczne
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 10.

Tytuł:: Krytyczne stężenie micelarne i metody jego wyznaczania
Critical micellar concentration and methods of its determination
Autorzy:: Piotrowska-Kirschling, A.
Drzeżdżon, J.
Chmurzyński, L.
Jacewicz, D.
Powiązania:: https://bibliotekanauki.pl/articles/172267.pdf
Data publikacji:: 2018
Wydawca:: Polskie Towarzystwo Chemiczne
Tematy:: związki powierzchniowo czynne
surfaktanty
krytyczne stężenie micelarne
micele
surface active compounds
surfactants
critical micellar concentration
micelles
Opis:: Surfactants are substances, which have surface activity in aqueous solutions [1–3]. By adsorbing on the surface (boundary of phase separation) of the system, they change the surfactant properties of the liquid. Surfactants consist of a hydrophobic part (non-polar, called “tail”) and a hydrophilic part (polar, called “head”) [1–3]. The overall structure of the surfactant molecule is shown in Figure 1. In aqueous solution after exceeding one critical micellar concentration of the CMC surfatant (Critical Micelle Concentration), the surfactant molecules aggregate to form micelles [1–5]. Knowledge of CMC values and the micelle formation in solution, it determines the properties of surfactants and their subsequent use in the chemical industry. Surfactants are used in the chemical industry, inter alia, for the production of many detergents, cosmetics, paints, dyes, agrochemicals, pharmaceuticals, food or oil [2, 3].
Źródło:: Wiadomości Chemiczne; 2018, 72, 11-12; 815-828
0043-5104
2300-0295
Pojawia się w:: Wiadomości Chemiczne
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 11.

Tytuł:: Probing of Cu2+ ions binding to A β (5−16) peptide using ITC measurements and MD simulations
Autorzy:: Makowska, J.
Żmudzińska, W.
Wyrzykowski, D.
Brzozowski, K.
Zblewska, H.
Chmurzyński, L.
Powiązania:: https://bibliotekanauki.pl/articles/1938620.pdf
Data publikacji:: 2016
Wydawca:: Politechnika Gdańska
Tematy:: A β (5 − 16) fragments
metal-peptide binding
isothermal titration calorimetry
molecular dynamics simulations
Opis:: It is shown that probably three residues: His6, His14 and His16 in the original sequence A β (1−42) serve as metal-binding sites for Cu2+ions. On the other hand, there is a possibility that only one of them plays a crucial role in the formation of the{A β (1-42)-Cu2+} complex. The isothermal titration calorimetry (ITC) measurements supported by molecular dynamic simulation (MD) with the NMR-derived restrains were used to investigate the interactions of Cu2+ with A β(5-16), a fragment of the A β(1-42) protein, with the following sequence: Ac-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-NH2, termed HZ1. The conditional thermodynamic parameters suggest that the formation of the Cu2+-HZ1 complex is both an enthalpy and entropy driven process under the experimental conditions. The studies presented here (after comparison with our previous results) show that the affinity of peptides to copper metal ions depends on two factors: the primary structure (amino acid composition) and the shape of the peptide conformation adopted.
Źródło:: TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk; 2016, 20, 4; 409-416
1428-6394
Pojawia się w:: TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk
Dostawca treści:: Biblioteka Nauki

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