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Wyszukujesz frazę "Chen, Xia" wg kryterium: Autor


Tytuł:
Design of broadband power line communication module for automatic meter reading
Autorzy:
Chen, Xia
Liu, Ling
Powiązania:
https://bibliotekanauki.pl/articles/949869.pdf
Data publikacji:
2020
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
automatic meter reading
low-power consumption
long-distance transmission
power line communication
Opis:
Low-power consumption and long-distance transmission are two problems that have to be solved by the application of broadband power line communication for the automatic meter reading system. To reduce the power consumption of the communication module, based on the analysis of the composition of the power consumption, some methods are proposed. From the communication chip level and the module circuit level, the design scheme of low-power consumption is given. To solve the problem of transmission distance, a frequency band of 2.44 MHz~5.6 MHz is used as the main working frequency band. The communication module supports multiple frequency bands. Using this feature, the optimal frequency band is adaptively selected for communication and automatic switching, which further improve the transmission distance. Field application shows that the above methods effectively decrease the power consumption of the communication module and extend the transmission distance.
Źródło:
Archives of Electrical Engineering; 2020, 69, 4; 771-780
1427-4221
2300-2506
Pojawia się w:
Archives of Electrical Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Fatigue reliability analysis of the brake pads considering strength degradation
Autorzy:
Zhang, Nan
Jiang, Guang-Jun
Wu, Dong-Wei
Chen, Hong-Xia
Wu, Jian-Xin
Powiązania:
https://bibliotekanauki.pl/articles/1841941.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Polskie Naukowo-Techniczne Towarzystwo Eksploatacyjne PAN
Tematy:
stress-strength interference model
dynamic reliability
strength degradation
impact load
Opis:
Reliability prediction of the brake pads is indispensable to guarantee their safety. In the paper, the fatigue reliability of brake pads is analyzed by dynamic stress-strength interference (SSI) model considering strength degradation. Firstly, reliability model of the brake pads was established based on stress-strength interference model considering the influence of impact load. Then reliability of the brake pads was predicted under different impact load frequency and initial strength. Finally, the influence of random degradation strength on reliability was studied by contrast. The analysis results show that random strength degradation, impact load and initial strength have great influence on reliability prediction for the brake pads. Therefore, the reliability prediction of the brake pads fatigue strength considering strength degradation is more in line with the actual situation and the calculation accuracy is higher.
Źródło:
Eksploatacja i Niezawodność; 2020, 22, 4; 620-626
1507-2711
Pojawia się w:
Eksploatacja i Niezawodność
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Simulation study on strength and failure characteristics of coal-rock composite sample with coal persistent joint
Badanie symulacyjne charakterystyk wytrzymałościowych próbki kompozytowej złożonej z materiału skalnego oraz węgla w którym występują płaszczyzny łupliwości
Autorzy:
Yin, Dawei
Chen, Shaojie
Chen, Bing
Xia, Zhiguo
Powiązania:
https://bibliotekanauki.pl/articles/219275.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
symulacja PFC
próbka kompozytowa złożona z węgla i materiału skalnego
spoistość węgla
charakterystyka wytrzymałościowa
ewolucja mikro-pęknięć
particle flow simulation
coal-rock composite sample
coal persistent joint
strength and failure characteristics
microcrack number evolution
Opis:
Dynamic Mine disasters can be induced by the instability and failure of a composite structure of rock and coal layers during coal mining. Coal seam contains many native defects, severely affecting the instability and failure of the compound structure. In this study, the effects of coal persistent joint on the strength and failure characteristics of coal-rock composite samples were evaluated using PFC2D software. The results show that with the increase of included angle α between the loading direction and joint plane direction, the uniaxial compressive stress (UCS) and peak strain of composite samples first decrease and then gradually increase. The elastic moduli of composite samples do not change obviously with α. The peak strain at α of 45° is the lowest, and the UCS at α of 30° is the smallest. This is inconsistent with theoretical analysis of lowest UCS at α of 45°. This is because that the local stress concentration caused by the motion inconformity of composite samples may increase the average axial stress of upper wall in PFC2D software. Moreover, the coal persistent joint promotes the transformation from the unstable crack expansion to the macro-instability of composite samples, especially at α of 30° and 45°. The majority of failures for composite samples occur within the coal, and no obvious damage is observed in rock. Their failure modes are shear failure crossing or along the coal persistent joint. The failure of composite sample at α of 30° is a mixed failure, including the shear failure along the persistent joint in coal and tensile failure of rock induced by the propagation of coal persistent joint.
Niekorzystne zjawiska dynamiczne w kopalniach mogą być wywołane przez niestabilność i pękanie struktur kompozytowych złożonych z warstw węgla i materiałów skalnych w trakcie eksploatacji górniczej. W złożu węgla ujawnić się mogą liczne defekty wewnętrzne, które w poważnym stopniu rzutują na stabilność i wytrzymałość złożonej struktury. W pracy tej zbadano wpływ spoistości węglu (występowania powierzchni łupliwości) na charakterystykę wytrzymałościową próbki kompozytowej złożonej z węgla i skały z wykorzystaniem oprogramowania PCF 2D. Wyniki symulacji wskazują, że wraz ze wzrostem kąta α pomiędzy kierunkiem działania obciążenia a płaszczyzną łupliwości, jednoosiowe naprężenie ściskające oraz maksymalne odkształcenie próbki kompozytowej w pierwszym etapie zmniejszą się, a następnie zaczną stopniowo wzrastać. Moduł sprężystości próbek kompozytowych nie ulega zmianie wraz ze zmianą kąta α. Maksymalne odkształcenie będzie najmniejsze dla kąta α równego 45°, z kolei jednoosiowe naprężenie ściskające zarejestrowane dla 30° okaże się najniższe. Wyniki te nie wykazują zgodności z wynikami analiz teoretycznych, przewidujących iż najniższe wartości jednoosiowego naprężenia ściskającego powinny wystąpić dla kąta 45°. Dzieje się tak dlatego, że lokalne koncentracje naprężeń wskutek odmienności zachowania poszczególnych składników próbki w trakcie ruchu powodować mogą wzrost średniego naprężenia osiowego ściany górnej, co uwzględnia model z wykorzystaniem oprogramowania PFC 2D. Ponadto, istnienie ciosu i płaszczyzn łupliwości sprawia, że niestabilne i propagujące szczeliny ulegają przekształceniu w makro- niestabilności próbek kompozytowych, zwłaszcza przy kącie α równym 30° i 45°. Większość pęknięć powstających w próbkach kompozytowych występuje w części węglowej, w pozostałych skałach nie notuje się poważniejszych uszkodzeń. Pęknięcia zmęczeniowe w części złożonej z materiału skalnego odbywają się wskutek działania naprężeń ścinających wzdłuż lub w poprzez płaszczyzny łupliwości. Pękanie zmęczeniowe próbki kompozytowej przy kącie α równym 30° jest procesem złożonym, obejmującym pękanie wskutek naprężeń ścinających działających wzdłuż płaszczyzny łupliwości w węglu oraz naprężeń rozciągających działających na część próbki złożoną z materiału skalnego, wskutek propagacji pęknięcia.
Źródło:
Archives of Mining Sciences; 2019, 64, 3; 609-623
0860-7001
Pojawia się w:
Archives of Mining Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
An incomplete soft set and its application in MCDM problems with redundant and incomplete information
Autorzy:
Xia, Sisi
Yang, Haoran
Chen, Lin
Powiązania:
https://bibliotekanauki.pl/articles/2055164.pdf
Data publikacji:
2021
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
soft set
incomplete soft set
incomplete information
redundant information
multiple criteria decision making
zbiór miękki
informacja niepełna
informacja zbędna
decyzja wielokryterialna
Opis:
Multiple criteria decision making (MCDM) problems in practice may simultaneously contain both redundant and incomplete information and are difficult to solve. This paper proposes a new decision-making approach based on soft set theory to solve MCDM problems with redundant and incomplete information. Firstly, we give an incomplete soft set a precise definition. After that, the binary relationships of objects in an incomplete soft set are analyzed and some operations on it are provided. Next, some definitions regarding the incomplete soft decision system are also given. Based on that, an algorithm to solve MCDM problems with redundant and incomplete information based on an incomplete soft set is presented and illustrated with a numerical example. The results show that our newly developed method can be directly used on the original redundant and incomplete data set. There is no need to transform an incomplete information system into a complete one, which may lead to bad decision-making due to information loss or some unreliable assumptions about the data generating mechanism. To demonstrate its practical applications, the proposed method is applied to a problem of regional food safety evaluation in Chongqing, China.
Źródło:
International Journal of Applied Mathematics and Computer Science; 2021, 31, 3; 417--430
1641-876X
2083-8492
Pojawia się w:
International Journal of Applied Mathematics and Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Endoreversible Four-Reservoir Chemical Potential Transformer with Diffusive Mass Transfer Law
Autorzy:
Xia, D.
Chen, L.
Sun, F.
Powiązania:
https://bibliotekanauki.pl/articles/1493376.pdf
Data publikacji:
2011-09
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
05.70.Ln
82.60.Lf
Opis:
The performance of an isothermal endoreversible four-reservoir chemical potential transformer, in which the mass transfer between the mass reservoir and the working medium obeys diffusive law, is analyzed and optimized in this paper. The relation between the rate of energy pumping and the coefficient of performance of the isothermal chemical potential transformer is derived by using finite-time thermodynamics. Moreover, the optimal operating regions and the influences of some parameters on the performance of the cycle are studied. The results obtained herein can provide some new theoretical guidelines for the optimal design of a class of apparatus such as mass exchangers, as well as electrochemical, photochemical, and solid-state devices, and the fuel pumps for solar-energy conversion systems.
Źródło:
Acta Physica Polonica A; 2011, 120, 3; 378-383
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Endoreversible Modeling and Optimization of a Multistage Heat Engine System with a Generalized Heat Transfer Law via Hamilton-Jacobi-Bellman Equations and Dynamic Programming
Autorzy:
Xia, S.
Chen, L.
Sun, F.
Powiązania:
https://bibliotekanauki.pl/articles/1504513.pdf
Data publikacji:
2011-06
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
05.70.-a
05.60.Cd
05.70.Ln
Opis:
A multistage endoreversible Carnot heat engine system operating between a finite thermal capacity high-temperature fluid reservoir and an infinite thermal capacity low-temperature environment with a generalized heat transfer law [q ∝ ( Δ $(T^{n}))^{m}$] is investigated in this paper. Optimal control theory is applied to derive the continuous Hamilton-Jacobi-Bellman equations, which determine the optimal fluid temperature configurations for maximum power output under the conditions of fixed initial time and fixed initial temperature of the driving fluid. Based on the general optimization results, the analytical solution for the case with Newtonian heat transfer law [q ∝ Δ(T)] is further obtained. Since there are no analytical solutions for the other heat transfer laws, the continuous Hamilton-Jacobi-Bellman equations are discretized and the dynamic programming algorithm is adopted to obtain the complete numerical solutions of the optimization problem, and the relationships among the maximum power output of the system, the process period and the fluid temperature are discussed in detail. The results show that the optimal high-temperature fluid reservoir temperature for the maximum power output of the multistage heat engine system with Newtonian and linear phenomenological [q ∝ Δ $(T^{-1})$] heat transfer laws decrease exponentially and linearly with time, respectively, while those with the Dulong-Petit [q∝$(Δ T)^{1.25}$], radiative [q∝ Δ $(T^4)$] and [q∝$(Δ(T^4))^{1.25}$] heat transfer laws are different from the former two cases significantly.
Źródło:
Acta Physica Polonica A; 2011, 119, 6; 747-760
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A new method for decision making problems with redundant and incomplete information based on incomplete soft sets: From crisp to fuzzy
Autorzy:
Xia, Sisi
Chen, Lin
Liu, Siya
Yang, Haoran
Powiązania:
https://bibliotekanauki.pl/articles/2172131.pdf
Data publikacji:
2022
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
decision-making
soft set
incomplete fuzzy soft set
incomplete information
redundant information
podejmowanie decyzji
zbiór miękki
informacja niepełna
informacja zbędna
Opis:
This research is focused on decision-making problems with redundant and incomplete information under a fuzzy environment. Firstly, we present the definition of incomplete fuzzy soft sets and analyze their data structures. Based on that, binary relationships between each pair of objects and the “restricted/relaxed AND” operations in the incomplete fuzzy soft set are discussed. After that, the definition of incomplete fuzzy soft decision systems is proposed. To reduce the inconsistency caused by the redundant information in decision making, the significance of the attribute subset, the reduct attribute set, the optimal reduct attribute set and the core attribute in incomplete fuzzy soft decision systems is also discussed. These definitions can be applied in an incomplete fuzzy soft set directly, so there is no need to convert incomplete data into complete one in the process of reduction. Then a new decision-making algorithm based on the above definitions can be developed, which can deal with redundant information and incomplete information simultaneously, and is independent of some unreliable assumptions about the data generating mechanism to forecast the incomplete information. Lastly, the algorithm is applied in the problem of regional food safety evaluation in Chongqing, China, and the corresponding comparison analysis demonstrates the effectiveness of the proposed method.
Źródło:
International Journal of Applied Mathematics and Computer Science; 2022, 32, 4; 657--669
1641-876X
2083-8492
Pojawia się w:
International Journal of Applied Mathematics and Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Noether Theorems and Discrete Variational Integrators in Field Theory
Autorzy:
Xia, Li-Li
Chen, Li-Qun
Liu, Chang-Xin
Powiązania:
https://bibliotekanauki.pl/articles/1398640.pdf
Data publikacji:
2015-03
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
02.20.Sv
11.30.-j
Opis:
The discrete analogue of the Noether-type identities in field theory is investigated by means of the difference discrete variational principle in which the difference is regarded as an entire geometric object. The discrete counterparts of the Noether theorems are obtained. It is proved that there exists the discrete version of the Noether conservation law in field theory. The discretization for the nonlinear Schrödinger equation is presented to illustrate the results.
Źródło:
Acta Physica Polonica A; 2015, 127, 3; 669-673
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Increasing nitrogen use efficiency with lower nitrogen application frequencies using zeolite in rice paddy fields
Autorzy:
Wu, Q.
Chen, T.
Chi, D.
Xia, G.
Sun, Y.
Song, Y.
Powiązania:
https://bibliotekanauki.pl/articles/2082479.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Instytut Agrofizyki PAN
Tematy:
available nitrogen
nitrogen uptake
root system
labour force
Opis:
Zeolite can effectively regulate the nutrient status in the root zone of crops, thereby increasing nitrogen utilization. However, there has been relatively little research conducted concerning a possible reduction in the frequency of nitrogen application due to the sustained-release properties of zeolite. In this study, 157.5 kg ha-1 nitrogen in the form of urea fertilizer was applied at the same rate, either as a one-time application or as a 3-way split application with and without 10 t ha-1 zeolite. The effects on rice yield, nitrogen uptake, root morphology and soil properties were evaluated in 2014 and 2015. Results showed that zeolite could enhance the biomass, leaf area index and nitrogen uptake. A higher rice grain yield and nitrogen uptake following soil treatment with zeolite could be attributed to a higher soil cation exchange capacity as well as nitrogen and potassium availability in the soil especially during the vegetative period of the rice plant. The addition of nitrogen to the soil as a one-time application or 3-way split application with 10 t ha-1 zeolite significantly increased rice grain yield by 8.5 or 10.7% compared with nitrogen as a one-time application without zeolite. Zeolite addition greatly improved the development of root morphology and activity compared with treatments without zeolite, which contributed to additional plant growth. The addition of nitrogen to the soil with 10 t ha-1 zeolite as a one-time application that can significantly increase nutrient retention is recommended to improve rice grain yield and decrease nitrogen application frequencies in order to lower both labour forces and energy requirements.
Źródło:
International Agrophysics; 2019, 33, 2; 263-269
0236-8722
Pojawia się w:
International Agrophysics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Design and Experiment on the Compact, Portable Pulse Forming Line
Autorzy:
Xia, L.
Shi, J.
Chen, D.
Zhang, H.
Zhang, L.
Deng, J.
Powiązania:
https://bibliotekanauki.pl/articles/1807991.pdf
Data publikacji:
2009-06
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
84.70.+p
77.90.+k
Opis:
Some research has been done on making the compact, portable pulse forming line. A kind of ceramic and a kind of newly developed composite polymer are both used as the dielectric of the planar pulse forming line. The ceramic's dielectric constant ranges from 200 to 600 and the composite polymer's dielectric constant ranges from 100 to 200. It is easier to manufacture the large composite polymer dielectric bulks than to manufacture the ceramic bulks. In the experiments, using the large composite polymer bulk as the dielectric, the planar Blumlein line generated the pulse up to 100 kV with duration 90 ns. Using the ceramic bulk as the dielectric, the planar line generated the voltage pulse up to 60 kV with duration 92 ns.
Źródło:
Acta Physica Polonica A; 2009, 115, 6; 1192-1193
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Molecular cloning, expression and characterization of Bmserpin-2 gene from Bombyx mori
Autorzy:
Pan, Ye
Xia, Hengchuan
Lü, Peng
Chen, KePing
Yao, Qin
Chen, Huiqin
Gao, Lu
He, Yuanqing
Wang, Lin
Powiązania:
https://bibliotekanauki.pl/articles/1040486.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
serpin-2
Bombyx mori
bioinformatics
subcellular location
qPCR
Opis:
Serpins are a broadly distributed family of protease inhibitors. In this study, the gene encoding Bombyx mori serpin-2 (Bmserpin-2) was cloned and expressed in E. coli. The Bmserpin-2 cDNA contains a 1125 bp open reading frame (ORF). The deduced protein has 374 amino-acid residues, contains a conserved SERPIN domain and shares extensive homology with other invertebrate serpins. RT-PCR analysis showed that Bmserpin-2 was expressed in all developmental stages of B. mori larvae and various larval tissues. Subcellular localization analysis indicated that Bmserpin-2 protein was located in the cytoplasm. Interestingly, real-time quantitative PCR revealed that the expression of Bmserpin-2 in the midgut of susceptible B. mori strain 306 significantly increased at 72 hours post inoculation (hpi) when infected with BmNPV. However, there was no significant increase of the Bmserpin-2 expression in resistant strain NB infected with BmNPV. Thus, our data indicates that Bmserpin-2 may be involved in B. mori antiviral response.
Źródło:
Acta Biochimica Polonica; 2009, 56, 4; 671-677
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Identification and tissue distribution of a novel rat glucocorticoid receptor splice variant
Autorzy:
Ju, Huiming
Wang, Xia
Liu, Zongping
Liu, Ping
Zhao, Yan
Xiong, Renping
Zhou, Yuanguo
Chen, Xingyun
Powiązania:
https://bibliotekanauki.pl/articles/1040640.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
glucocorticoid
glucocorticoid receptor
receptor isoform
splice variant
Opis:
Glucocorticoid receptor (GR) is a steroid hormone receptor that has been shown to play important roles in diverse cellular and physiological processes. More and more evidence has revealed that the effects of glucocorticoids are mediated by the glucocorticoid receptor through genomic or nongenomic mechanisms. A growing number of glucocorticoid receptor splice variants have been identified in human tissues, but few are known in rat tissues. In this work, a novel rGR cDNA, called rGRβ, was cloned from Sprague Dawlay (SD) rat liver. Sequence analysis revealed that the rGRβ mRNA was 39 base pairs (bp) shorter than the rGR mRNA reported earlier. The deleted segment is located in exon 1 and encodes 13 repeated glutamine residues. Both the rGR and rGRβ mRNAs were quantitated by Northern blot hybridization using non-homologous glucocorticoid cDNA probes. Results showed that the rGR and rGRβ mRNAs were most abundant in the lung, the least abundant in the heart, and there were more rGR and rGRβ mRNAs in the kidney than in the liver. The identification of rGRβ may contribute to the understanding of the genomic or nongenomic effects of glucocorticoids.
Źródło:
Acta Biochimica Polonica; 2009, 56, 1; 109-113
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Identification of three species commonly known as“daqingye” by internal leaf anatomy and high-performance liquid chromatography analyses
Autorzy:
Zhang, Y.
Zhu, Y.
Chen, J.
Xia, C.
Deng, J.
Li, H.
Li, Y.
Li, J.
Liu, P.
Powiązania:
https://bibliotekanauki.pl/articles/59301.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Botaniczne
Opis:
The macroscopic and microscopic morphologies and indigo and indirubin concentration of the traditional Chinese medicine herbs Isatis indigotica Fort., Polygonum tinctorium Ait., and Baphicacanthus cusia (Nees) Bremek, all commonly known as “daqingye”, were determined and compared. The morphological analyses indicated that I. indigotica has leaves with winged petioles and no glandular hairs or crystals, P. tinctorium has leaves with membranous ocrea and clusters of calcium oxalate, and B. cusia has palisade cells in the mesophyll running over the main vein and single cells containing calcium carbonate crystals. Indigo and indirubin are chemical constituents that have been previously isolated from daqingye and were selected in this study as identification markers for high-performance liquid chromatography analysis due to their pharmacological activities. The chromatographic results showed that indigo and indirubin concentration varied significantly among the three species: high concentration of both indigo and indirubin were observed in I. indigotica, the highest concentration among the three daqingye plants was found in P. tinctorium but with low levels of indirubin, and the concentration of indigo and indirubin was quite low in B. cusia. In summary, three different species commonly known as daqingye were accurately distinguished by morphological observation, internal leaf anatomy analysis, and chromatographic analysis.
Źródło:
Acta Societatis Botanicorum Poloniae; 2018, 87, 1
0001-6977
2083-9480
Pojawia się w:
Acta Societatis Botanicorum Poloniae
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Influence of oleic acid in different solvent media on BRL 3A cell growth and viability
Autorzy:
Liu, Runqi
Yang, Wei
Xia, Cheng
Chen, Yuanyuan
Gao, Sansi
Dong, Zhihao
Huang, Baoyin
Li, Ruirui
He, Ping
Xu, Chuang
Powiązania:
https://bibliotekanauki.pl/articles/1038377.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
oleic acid
non-alcoholic fatty liver disease
liver lipid deposition
Opis:
Oleic acid (OA) is widely used in pathology studies of hepatocellular lipid deposition. Identifying the effects of different solvents on OA-induced liver lipid deposition would be beneficial for studies on hepatocytes. We treated BRL 3A cells with OA dissolved in different solvents. After 12 h incubation, cell viability was assessed using MTT assays. Reactive oxygen species (ROS), triglyceride (TG) and total cholesterol (TC) counts, and the expression level of glucose regulated protein (GRP78), sterol regulatory element binding protein (SREBP-1C) and fatty acid synthase (FAS) were analyzed. Water, PBS and DMSO were disadvantageous to the dissolution of OA and did not cause an OA-induced response in hepatocytes. In the alcohol+OA-treated cells, the severe ER stress, oxidative stress and cellular fat deposition were significantly increased. BSA promoted cell growth and the cells treated with 1.2% BSA+OA showed a lower grade TG and endoplasmic reticulum stress compared with KOH+OA and alcohol+OA treatments. KOH had no significant influence on BRL 3A cells viability. When treated with OA dissolved in KOH, BRL 3A cells showed a typical hepatocyte damage. KOH was considered the suitable choice for an OA solvent for BRL 3A cells in hepatic lipidosis research.
Źródło:
Acta Biochimica Polonica; 2018, 65, 3; 443-447
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The relationship between manganism and the workplace environment in China
Autorzy:
Wang, Yongyi
Xue, Jian
Cheng, Shuqun
Ding, Yubin
He, Junlin
Liu, Xueqing
Chen, Xuemei
Wang, Yingxiong
Feng, Xiangyu
Xia, Yinyin
Powiązania:
https://bibliotekanauki.pl/articles/2180079.pdf
Data publikacji:
2012-09-01
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
manganese
occupational exposure
welding
mining
occupational intoxication
chronic manganism
Opis:
Manganese is a trace element and a cofactor of many enzymes, so it is essential for physiologic functioning, but it is also a neurotoxin at high doses. Manganism is most often caused by occupational exposure. It is manifested by a myriad of signs and symptoms ranging from the neurasthenia syndrome, such as headache and dizziness, to the Parkinson-like syndrome, depending on the blood manganese levels as well as the duration of exposure. We are reporting a case of manganism using both clinical and occupational hygiene investigation methods. The patient presented the neurasthenia syndrome accompanied by hypertonicity of arm muscles and was diagnosed to have mild chronic manganism. Finally, the patient was discharged from the hospital after the treatment had improved her condition. In China, there are many chronic manga nese cases, partly due to a rapid industrial development with great use of Mn and the low self-protection awareness among the workers and the factories management that cannot catch up with the speed of the economical development. Therefore, factories are responsible for improving the conditions at the workplace.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2012, 25, 4; 501-505
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł

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