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Wyświetlanie 1-15 z 42
Tytuł:
Almost everywhere convergence of Laguerre series
Autorzy:
Chen, Chang-Pao
Lin, Chin-Cheng
Powiązania:
https://bibliotekanauki.pl/articles/1290468.pdf
Data publikacji:
1994
Wydawca:
Polska Akademia Nauk. Instytut Matematyczny PAN
Tematy:
almost everywhere convergence
Cesàro means
Laguerre polynomials
Riesz means
Opis:
Let $a ∈ ℤ^+$ and $f ∈ L^p (ℝ^+), 1 ≤ p ≤ ∞ $. Denote by $c_j$ the inner product of f and the Laguerre function $ℒ^a_j$. We prove that if ${c_j}$ satisfies $lim_{λ↓1} \overline lim_{n→∞} ∑_{n
Źródło:
Studia Mathematica; 1994, 109, 3; 291-301
0039-3223
Pojawia się w:
Studia Mathematica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Badania okresu gwarancyjnego dla systemu wieloskładnikowego, w którym zachodzą interakcje uszkodzeniowe
Research on warranty interval of multi-component system with failure interaction
Autorzy:
Cheng, Z. H.
Bai, Y. S.
Cai, L. Y.
Wang, L. Ch.
Li, P. J.
Chen, L.
Powiązania:
https://bibliotekanauki.pl/articles/301278.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Polskie Naukowo-Techniczne Towarzystwo Eksploatacyjne PAN
Tematy:
okres gwarancyjny
koszty
dostępność
interakcje uszkodzeniowe
wieloelementowy
warranty period
cost
availability
failure interaction
multi-component
Opis:
W oparciu o analizę interakcji uszkodzeniowych, przyjęto dla systemu wieloskładnikowego politykę gwarancyjną obejmującą niepełną odnowę profilaktyczną. Zbadano średnią intensywność uszkodzeń dla każdego okresu gwarancyjnego oraz skonstruowano modele kosztów obsługi gwarancyjnej oraz dostępności biorąc pod uwagę intensywność uszkodzeń interakcyjnych. Jako przykład podano projekt okresu gwarancyjnego, który może potwierdzić poprawność przyjętego modelu oraz przedstawiono zalety takiego projektu. W badaniach opracowano technikę i metody ustalania okresu gwarancyjnego dla systemów wieloskładnikowych, które stanowią istotny wkład do teorii gwarancji.
Based on the analysis of failure interaction, imperfect preventive warranty policy is adopted for the multi-component system. Average failure rate of each warranty interval is studied and warranty cost model and availability model are built as viewed from interactive failure rate. Then Warranty period project is brought forward as an example, which can validate the feasibility of model and show the advantage of the project. The research can provide technique and methods for determining Warranty Period of multi-component system, which further enriches and perfects the warranty theory.
Źródło:
Eksploatacja i Niezawodność; 2011, 4; 49-55
1507-2711
Pojawia się w:
Eksploatacja i Niezawodność
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Myocardial remodeling in rats with metabolic syndrome: role of Rho-kinase mediated insulin resistance
Autorzy:
Li, Chuan-Bao
Li, Xiao-Xing
Chen, Yu-Guo
Gao, Hai-Qing
Bao, Cheng-Mei
Liu, Xiang-Qun
Bu, Pei-Li
Zhang, Juan
Zhang, Yun
Ji, Xiao-Ping
Powiązania:
https://bibliotekanauki.pl/articles/1039743.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Rat
Metabolism
Myocardium
Phosphorylation
Insulin resistance
Opis:
Insulin resistance (IR) plays a critical role in metabolic syndrome (MS). Previous studies have demonstrated that activated ROCK is increased in MS patients. However, the effect of Rho-kinase (ROCK) on IR has not been definitely determined. Thus, the aims of the present study were to determine whether ROCK activation induces IR or affects myocardial structure and function, as well as the possible mechanisms underlying this process. Wistar rats fed high fat, high glucose and high salt diet sewed as model of MS and we used transmission electron microscopy, echocardiogram technology, and terminal deoxynucleotidyl transferase-mediated DNA nick-end labeling staining to identify any myocardial damage. The protein levels of MYPT-1 (characteristic of ROCK activation), IRS-1 and AKT were analyzed by immunohistochemistry and Western blotting. In hearts from MS rats, we found increased protein levels of phospho-MYPT-1 and phospho-IRS-1 (Ser307) and decreased phospho-AKT compared to levels in normal rats. In conclusion, the results suggest that ROCK-mediated IR is involved in the development of myocardial impairments in MS rats and that this effect is mediated probably via the IRS-1/PI3-kinase/AKT pathway.
Źródło:
Acta Biochimica Polonica; 2012, 59, 2; 249-254
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The relationship between manganism and the workplace environment in China
Autorzy:
Wang, Yongyi
Xue, Jian
Cheng, Shuqun
Ding, Yubin
He, Junlin
Liu, Xueqing
Chen, Xuemei
Wang, Yingxiong
Feng, Xiangyu
Xia, Yinyin
Powiązania:
https://bibliotekanauki.pl/articles/2180079.pdf
Data publikacji:
2012-09-01
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
manganese
occupational exposure
welding
mining
occupational intoxication
chronic manganism
Opis:
Manganese is a trace element and a cofactor of many enzymes, so it is essential for physiologic functioning, but it is also a neurotoxin at high doses. Manganism is most often caused by occupational exposure. It is manifested by a myriad of signs and symptoms ranging from the neurasthenia syndrome, such as headache and dizziness, to the Parkinson-like syndrome, depending on the blood manganese levels as well as the duration of exposure. We are reporting a case of manganism using both clinical and occupational hygiene investigation methods. The patient presented the neurasthenia syndrome accompanied by hypertonicity of arm muscles and was diagnosed to have mild chronic manganism. Finally, the patient was discharged from the hospital after the treatment had improved her condition. In China, there are many chronic manga nese cases, partly due to a rapid industrial development with great use of Mn and the low self-protection awareness among the workers and the factories management that cannot catch up with the speed of the economical development. Therefore, factories are responsible for improving the conditions at the workplace.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2012, 25, 4; 501-505
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Thermodynamic and Electronic Properties of $OsB_2$ from First-Principles Calculations
Autorzy:
Cheng, Y.
Yang, J.
Wang, Y.
Ji, G.
Chen, X.
Powiązania:
https://bibliotekanauki.pl/articles/1365243.pdf
Data publikacji:
2014-05
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
71.15.Mb
61.50.Ks
67.25.de
71.20.-b
Opis:
The pressure induced phase transitions of $OsB_2$ from the orthorhombic structure (Orth) to the hexagonal structure (Hex) is investigated by using ab initio plane-wave pseudopotential density functional theory, together with quasi-harmonic Debye model. We find that the pressure-induced phase transition occurs at 2.8 GPa and 12.5 GPa by local density approximation and general gradient approximation, respectively. It is predicted that $OsB_2$ has no phase transition temperature from the Orth structure to the Hex structure. Moreover, the dependences of the relative volume V/$V_0$ on the pressure, thermal expansion coefficient α on the pressure and temperature are also successfully obtained. The electronic properties including energy band, total and partial density of states and electron density difference for two structures are also analyzed. The Mulliken charges and Bond populations for both Orth and Hex structures are also obtained.
Źródło:
Acta Physica Polonica A; 2014, 125, 5; 1186-1190
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Validation of School Core Competence Scale for Undergraduates: Empirical Findings of Taiwan Case
Autorzy:
Wu, Shwu Ming
Yang, Cheng Hong
Hsu, Wan Chen
Powiązania:
https://bibliotekanauki.pl/articles/2031728.pdf
Data publikacji:
2014-09-30
Wydawca:
Wydawnictwo Adam Marszałek
Tematy:
School Core Competence Scale
validation studies
Taiwanese undergraduates
Opis:
This study aimed to validate the 25-item School Core Competence Scale (SCCS) of the National Kaohsiung University of Applied Sciences. Item analysis and exploratory factor analysis were utilized with 368 undergraduates and confirmatory factor analysis with another 384 undergraduates. The SCSS had eight subscales, including Communication and Expression, International Perspective, Humanity, Civics and Morals, Professional Knowledge and Skills, Integrative Learning, Passion and Anti-stress, and Self-discipline. Results indicated that the SCCS is a valid and reliable instrument among undergraduates. Particularly, women scored higher on Communication and Expression, Civics and Morals, Self-discipline as well as the total scale.
Źródło:
The New Educational Review; 2014, 37; 95-105
1732-6729
Pojawia się w:
The New Educational Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Acquisition of the Surface Morphology of Ruled Gratings with a Microscope Objective
Autorzy:
Li, Z.
Ma, L.
Liu, C.
Zhang, M.
Chen, X.
Cheng, C.
Powiązania:
https://bibliotekanauki.pl/articles/1189791.pdf
Data publikacji:
2015-06
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
42.30.Kq
42.87.-d
42.79.Dj
42.40.Kw
Opis:
In this paper, an optical microscope objective with large numerical number is inserted into a Mach-Zehnder interferometer, and this system is adopted to detect the surface morphologies of two ruled transmission gratings with area scale to a micrometer. The object waves transmitting from the gratings interfere with spherical reference wave, and the interferograms constructed are recorded by a high-resolution CCD. The surface maps of the gratings are retrieved from the interferograms, and the results are confirmed by the measurement with an atomic force microscope, with detection errors in nanometer scale. This work provides an optical non-destructive method for precise detection of small-area sophisticated object surfaces with an optical microscope objective.
Źródło:
Acta Physica Polonica A; 2015, 127, 6; 1630-1633
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Spin Chain in Magnetic Field: Limitations of the Large-N Mean-Field Theory
Autorzy:
Wohlfeld, K.
Chen, Cheng-Chien
van Veenendaal, M.
Devereaux, T.
Powiązania:
https://bibliotekanauki.pl/articles/1384813.pdf
Data publikacji:
2015-02
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
71.10.Fd
75.10.Jm
75.10.Pq
Opis:
Motivated by the recent success in describing the spin and orbital spectrum of a spin-orbital chain using a large-N mean-field approximation, we apply the same formalism to the case of a spin chain in the external magnetic field. It occurs that in this case, which corresponds to N=2 in the approximation, the large-N mean-field theory cannot qualitatively reproduce the spin excitation spectra at high magnetic fields, which polarize more than 50% of the spins in the magnetic ground state. This, rather counterintuitively, shows that the physics of a spin chain can under some circumstances be regarded as more complex than the physics of a spin-orbital chain.
Źródło:
Acta Physica Polonica A; 2015, 127, 2; 201-203
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Utilizing the metabolic syndrome component count in workers’ health surveillance: An example of day-time vs. day-night rotating shift workers
Autorzy:
Lin, Yu Cheng
Hsieh, I-Chun
Chen, Pau-Chung
Powiązania:
https://bibliotekanauki.pl/articles/2177229.pdf
Data publikacji:
2015-07-01
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
metabolic syndrome
day-and-night rotating shift work
occupational health
physical examination
Opis:
Objectives To establish a practical method for assessing the general metabolic health conditions among different employee groups, this study utilized the total count of metabolic syndrome (MetS) elements as a parameter, and performed a retrospective analysis comparing changes of MetS component count (MSC) of 5 years among day-time work (DW) and day-andnight rotating shift work (RSW) employees. Material and Methods The data of personal histories, physical examinations, blood tests, abdominal sonographic examinations and occupational records were collected from a cohort of workers in an electronics manufacturing company. We first defined the arithmetic mean value of MSC as MSC density (MSCD) for the employee group; then we compared the changes of MSCD over 5 years between DW and RSW workers. Occupational, personal and health records were analyzed for the 1077 workers with an initial mean age of 32.4 years (standard deviation (SD): 6.2 years), including 565 RSW workers (52%). Results The initial MSCDs were 1.26 and 1.12 (p = 0.06) for DW and RSW workers, respectively; after 5 years, the increments of MSCD for DW and RSW workers were 0.10 and 0.39, respectively (p < 0.01). By performing multivariate logistic regression analyses, and comparing with DW co-workers, final results indicated that the workers exposed to RSW have 1.7-fold increased risk of elevated MSCD (95% confidence interval (CI): 1.28–2.25, p < 0.01); and are 38% less likely (adjusted rate ratio (aRR) 0.62, 95% CI: 0.45–0.86, p < 0.01) to attain decreased MSCD. Conclusions These observations demonstrate that changes of MSCD are significantly different between DW and RSW workers, and are increasingly associated with RSW exposure. In conclusion, MSCD can represent the general metabolic health conditions of a given employee group; MSC, MSCD and their transitional changes can be applied as simple and standardized tools for monitoring metabolic health risk profiles when managing employee health, at both the individual and company levels.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2015, 28, 4; 675-688
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A unified calculation of the optical and EPR spectral data for the trigonal Cr³⁺ center in Cr³⁺-doped α-RbAl(SO₄)₂·12H₂O alum crystal
Autorzy:
Li, Xiao-Wu
Mei, Yang
Wei, Cheng-Fu
Zheng, Wen-Chen
Powiązania:
https://bibliotekanauki.pl/articles/1070555.pdf
Data publikacji:
2016-03
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
71.70.Ch
76.30.Fc
78.40.Ha
78.55.Hx
Opis:
The optical band positions and the spin-Hamiltonian parameters (g factors g_{∥}, g_{⊥}, and zero-field splitting parameter D) of alum α-RbAl(SO₄)₂·12H₂O:Cr³⁺ are calculated by diagonalizing the 120× 120 complete energy matrix based on the two-spin-orbit-coupling-parameter model. The model takes into account not only the contributions due to the spin-orbit-coupling parameter of central d^{n} ion in the conventional crystal field theory, but also those due to ligands via covalence effect. The calculation indicates that the fourteen observed spectral data (eleven optical band positions and three spin-Hamiltonian parameters) can be reasonably and uniformly explained with four adjustable parameters (the Racah parameters B, C, intrinsic parameter A̅₄(R) in the superposition model, and the trigonal distortion angle β). The calculations also suggest that contrary to the previous findings, the trigonal distortion of Cr³⁺ (entering the Al³⁺ site in the host crystal) center in α-RbAl(SO₄)₂·12H₂O is induced mainly by the oxygen (or water) octahedron around the Cr³⁺ ion rather than the more distant neighbors.
Źródło:
Acta Physica Polonica A; 2016, 129, 3; 340-343
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Research on the disturbance generated by a solar array drive assembly driving a flexible system
Autorzy:
Chen, J.
Cheng, W.
Powiązania:
https://bibliotekanauki.pl/articles/949310.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
Tematy:
solar array drive assembly
disturbance
flexible system
electromagnetic torque
vibration equation
Opis:
The present work is aimed at presenting the disturbance generated by a solar array drive assembly (SADA) driving a flexible system. Firstly, the vibration equation of SADA is obtained by simplifying and linearizing the electromagnetic torque. Secondly, the disturbance model of SADA driving a discrete flexible system is achieved based on the vibration equation established. Taking a two-dof flexible system as the study object, this disturbance model is simulated and analyzed. Lastly, a continuous flexible system, which is designed to simulate the solar array, is used to illustrate the simulation method of the disturbance emitted by SADA driving a continuous flexible system. All the achievements obtained from this project will provide a theoretical basis for the prediction of the disturbance emitted by the SADA driving solar array on the orbit.
Źródło:
Journal of Theoretical and Applied Mechanics; 2016, 54, 3; 1001-1012
1429-2955
Pojawia się w:
Journal of Theoretical and Applied Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Use of nanofiltration membranes to concentrate and recover leached aluminum from acidified water treatment sludge
Autorzy:
Cheng, W. P.
Chen, P. H.
Tian, D. R.
Yu, R. F.
Fu, C. H.
Powiązania:
https://bibliotekanauki.pl/articles/208030.pdf
Data publikacji:
2016
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
water purification
nanofiltration
acidic solutions
leaching
roztwory kwaśne
oczyszczanie wody
nanofiltracja
ługowanie
glin
Opis:
The recovery of aluminum from water purification sludge is usually performed by making the solution acidic or basic. However, for economic reasons and reasons of safety, excessive doses of acid or base should not be utilized. Accordingly, the aluminum concentration in the leached solution is typically limited, thus the recovered aluminum cannot be directly reused as a coagulant. A nanofiltration (NF) membrane can be used in the acidic solution to concentrate high-valence metal ions. There-fore, in this work, H2SO4 was utilized to leach Al3+ ions from water purification sludge. Then, the Al3+ ion solution was concentrated using a low-price NF membrane. The effect of natural organic matter on the Al3+ ion concentrating efficiency in the filtration process has been elucidated. Experimental results reveal that Al3+ ions were effectively prevented from passing through the NF membrane, enabling a highly concentrated aluminum solution to be obtained. However, the presence of organic compounds may reduce the efficiency of the concentration of Al3+ ions in the solution.
Źródło:
Environment Protection Engineering; 2016, 42, 3; 19-32
0324-8828
Pojawia się w:
Environment Protection Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effects of benzo(a)pyrene exposure on the ATPase activity and calcium concentration in the hippocampus of neonatal rats
Autorzy:
Yang, Kai
Chen, Chengzhi
Cheng, Shuqun
Cao, Xianqing
Tu, Baijie
Powiązania:
https://bibliotekanauki.pl/articles/2161850.pdf
Data publikacji:
2017-03-30
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
hippocampus
neurodevelopment
ATPase activity
Ca2+ concentration
neonatal rats
Benzo(a)pyrene
Opis:
Objectives To investigate whether postnatal benzo(a)pyrene (B(a)P) exposure caused the impairments on the process of neurodevelopment and the alteration in the calcium medium in the neonatal rats. Material and Methods Eighty neonatal Sprague Dawley (SD) rats were randomly divided into 5 groups (untreated control group, vehicle group, 0.02 mg/kg, 0.2 mg/kg and 2 mg/kg B(a)P-exposed group). Rats were treated with B(a)P by the intragastric administration from postnatal day (PND) 4 to 25. Morris water maze (MWM) was employed to observe the spatial memory of rats. The activity of calcium adenosine triphosphatase (Ca2+-ATPase), sodium-potassium adenosine triphosphatase (Na+-K+-ATPase) and calcium-magnesium adenosine triphosphatase (Ca2+-Mg2+-ATPase) in the hippocampus were detected by commercial kits. Fura-2 pentakis(acetoxymethyl) (Fura-2/AM) probe and reactive oxygen species (ROS) reagent kit were used for measuring the concentration of Ca2+ and ROS in the hippocampus synapse, respectively. Results Rats exposed to B(a)P resulted in the deficits in the spatial memory manifested by the increased escape latency and decreased number of crossing platform and time spent in target quadrant in comparison with the control groups. Benzo(a)pyrene exposure caused the significant decrease in the ATPase activity in the hippocampus and caused Ca2+ overload in the synaptic, besides, the ROS concentration increased significantly which may further induce neurobehavioral impairment of the neonatal rats. Conclusions Our findings suggest that postnatal B(a)P exposure may cause the neurobehavioral impairments in the neonatal rats, which were mediated by the decreased ATPase activity and elevated Ca2+ concentration. Int J Occup Med Environ Health 2017;30(2):203–211
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2017, 30, 2; 203-211
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Student Perception of Teacher Empathy, High Regard and Genuineness and the Impact on Student Engagement
Autorzy:
Bockmier-Sommers, Denise
Chen, Cheng-Chia "Brian"
Martsch, Martin
Powiązania:
https://bibliotekanauki.pl/articles/426459.pdf
Data publikacji:
2017
Wydawca:
Szkoła Główna Handlowa w Warszawie
Opis:
One of the main challenges for online instructors involves developing relationships with students. Current research in student engagement has conceptualized this process according to four areas: skill engagement, interaction engagement, emotional engagement, and performance engagement. In an effort to be more focused and to highlight the relationship-building aspect of engagement, the work of Carl Rogers can be applied in these settings by emphasizing empathy, genuineness, and high regard. This study sought to examine the relationship between student engagement and these Rogerian characteristics. Students (n=185) completed an online survey that included the Student Course Engagement Questionnaire and the Barrett-Leonard Relationship Inventory. The results demonstrated that empathy and high regard were significantly correlated with all four engagement areas, and genuineness was significantly correlated with three: interaction, emotional, and performance engagement. As hypothesized, empathy and high regard exhibited the strongest relationships with interaction engagement and emotional engagement. These findings suggest that student engagement (interaction and emotional) does capture aspects of these relationship-building variables. It also suggests that more can be done to measure and implement empathy, genuineness, and high regard skills in online teaching for more effective instruction.
Źródło:
e-mentor. Czasopismo naukowe Szkoły Głównej Handlowej w Warszawie; 2017, 3 (70); 66-72
1731-6758
1731-7428
Pojawia się w:
e-mentor. Czasopismo naukowe Szkoły Głównej Handlowej w Warszawie
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ezetimibe prevents myocardial remodeling in an obese rat model by inhibiting inflammation
Autorzy:
Li, Xiao-Xing
Zhao, Lang
Chang, Ying
Liu, Bao-Shan
Xu, Feng
Zhang, Cheng
Ji, Xiao-Ping
Chen, Yu-Guo
Li, Chuan-Bao
Powiązania:
https://bibliotekanauki.pl/articles/1038380.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
obese
inflammation
remodeling
ezetimibe
IL-6
Opis:
Inflammation plays an important role in the development of many obesity-related diseases. This study aimed to investigate the effect of ezetimibe on inflammation and myocardial remodeling in obese rats. A rat model of obesity was established, and myocardial damage was examined by transmission electron microscopy and Masson staining. Twenty obese rats were divided into two groups (n=10): obese group and ezetimibe group. Ten SD rats were used as controls. Western blot was performed to monitor the expression of P-p38MAPK and interleukin (IL)-6. Immunohistochemical staining was used to monitor the expression of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1. In the obese rats group, we observed increased inflammatory factors and myocardial hypertrophy. In contrast, the ezetimibe group exhibited decreased expression of inflammatory factors and an improvement in myocardial remodeling compared to the obese group. Mechanistically, we found that ezetimibe decreased P-p38MAPK, IL-6, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 levels in the hearts of the obese rats. Taken together, these results indicate that ezetimibe may improve myocardial remodeling in obese rats by inhibiting inflammation.
Źródło:
Acta Biochimica Polonica; 2018, 65, 3; 465-470
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
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