- Tytuł:
- Computational analysis of aortic hemodynamics during total and partial extra-corporeal membrane oxygenation and intra-aortic balloon pump support
- Autorzy:
-
Caruzo, M. V.
Gramigna, V.
Renzulli, A.
Fragomeni, G. - Powiązania:
- https://bibliotekanauki.pl/articles/306638.pdf
- Data publikacji:
- 2016
- Wydawca:
- Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
- Tematy:
-
Extracorporeal Membrane Oxygenation
ECMO
Intra-Aortic Balloon Pump
IABP
Computation Fluid Dynamic
CFD
Multiscale Model
Aorta
krążenie pozaustrojowe
aorta
model wieloskalowy - Opis:
- Purpose: The extracorporeal membrane oxygenation (ECMO) is a temporary, but prolonged circulatory support for cardiopulmonary failure. Clinical evidence suggests that pulsed flow is healthier than non pulsatile perfusion. The aim of this study was to computationally evaluate the effects of total and partial ECMO assistance and pulsed flow on hemodynamics in a patient-specific aorta model. Methods: The pulsatility was obtained by means of the intra-aortic balloon pump (IABP), and two different cases were investigated, considering a cardiac output (CO) of 5 L/min: Case A – total assistance – the whole flow delivered through the ECMO arterial cannula; Case B – partial assistance – flow delivered half through the cannula and half through the aorta. Computational fluid dynamic (CFD) analysis was carried out using the multiscale approach to couple the 3D aorta model with the lumped parameter model (resistance boundary condition). Results: In case A pulsatility followed the balloon radius change, while in case B it was mostly influenced by the cardiac one. Furthermore, during total assistance, a blood stagnation occurred in the ascending aorta; in the case of partial assistance, the flow was orderly when the IABP was on and was chaotic when the balloon was off. Moreover, the mean arterial pressure (MAP) was higher in case B. The wall shear stress was worse in ascending aorta in case A. Conclusions: Partial support is hemodynamically advisable.
- Źródło:
-
Acta of Bioengineering and Biomechanics; 2016, 18, 3; 3-9
1509-409X
2450-6303 - Pojawia się w:
- Acta of Bioengineering and Biomechanics
- Dostawca treści:
- Biblioteka Nauki
Artykuł