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Tytuł:
Evaluation of changes in fuel delivery rate by electromagnetic injectors in a common rail system during simulated operation
Autorzy:
Kamiński, Mariusz
Budzyński, Piotr
Hunicz, Jacek
Józwik, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/1841746.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Polskie Naukowo-Techniczne Towarzystwo Eksploatacyjne PAN
Tematy:
common rail
fuel delivery rate
injector operation
Opis:
The objective of this study was to determine changes in fuel delivery rate by common rail system injectors during their simulated operation on a test stand. Four Bosch injectors used, among others, in Fiat 1.3 Multijet engines were tested. The injectors were operated on a test rig at room temperature for 500 hours (more than 72 million work cycles). During the test, pressure and injection frequency were changed. Changes in the operating parameters were estimated based on obtained injection characteristics and effective flow area determined thereby. The observed changes in fuel delivery rate were compared with results of the surface analysis of control valves and nozzle needles. Despite the stated lack of wear, significant changes in the dynamics of injector operation were observed, particularly at short injection times. Small pilot injections cannot be corrected by the fuel injection control system because they do not affect the changes in torque; however, they do affect the combustion process. This creates conditions for increased emission of toxic exhaust components.
Źródło:
Eksploatacja i Niezawodność; 2021, 23, 2; 352-358
1507-2711
Pojawia się w:
Eksploatacja i Niezawodność
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Comparing of Microhardness of the Stellite 6 Cobalt Alloy Implanted with 175 keV Mn+ Ions and 120 keV N+ Ions
Autorzy:
Kamiński, Mariusz
Budzyński, Piotr
Szala, Mirosław
Turek, Marcin
Powiązania:
https://bibliotekanauki.pl/articles/103323.pdf
Data publikacji:
2019
Wydawca:
Stowarzyszenie Inżynierów i Techników Mechaników Polskich
Tematy:
ion implantation
Stellite 6
microhardness
cobalt alloy
implantacja jonów
Stellit 6
mikrotwardość
stop kobaltu
Opis:
Nowadays, high-precision machines require lightweight materials with very high strength. Ion implantation is used to improve the mechanical strength of the material. A further paper presents the influence of manganese and nitrogen ion implantation on changes of microhardness of the surface layer of cobalt alloy. Samples were analyzed with the SEM-EDS Phenom ProX microscope. Microhardness was assessed with the Vickers method, and the loads of 1 gf (0.00981 N) and 5 gf (0.049 N) was applied using a FM-800 from Future-Tech microhardness meter. At a load of 1 gf, the penetration depth of the implanted specimens was reached not exceeding 0.5 um. At this depth, all samples showed an increase in microhardness compared to the unimplanted sample. The highest increase in microhardness was achieved after implantation of Mn ions with dose D=1∙1017 Mn+/cm2 and energy E=175 keV. The increased load on the indenter to 5 gf reduced the microhardness differences between implanted and unimplanted samples.
Źródło:
Advances in Science and Technology. Research Journal; 2019, 13, 3; 179-185
2299-8624
Pojawia się w:
Advances in Science and Technology. Research Journal
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Application of the Single Access Technique in Laparoscopic Surgery
Autorzy:
Strzałka, Marcin
Matyja, Maciej
Matłok, Maciej
Migaczewski, Marcin
Budzyński, Piotr
Budzyński, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1396053.pdf
Data publikacji:
2013-02-01
Wydawca:
Index Copernicus International
Tematy:
laparoscopy
single access technique
results
Opis:
Laparoscopic single access technique is a next step in development of minimally invasive surgery. The aim of the study was to present results of different laparoscopic single incision procedures and evaluate application of this technique. Material and methods. 102 patients (15 males and 87 females) who underwent laparoscopic single incision procedure from 15th October 2009 to 31st December 2012 were included in the study. Results. In the analyzed period we performed 72 cholecystectomies (70.6%), 8 left adrenalectomies (7.8%), 3 right adrenalectomies (2.9%), 7 splenectomies (6.9%), 5 spleen cysts unroofings (4.9%), 2 appendectomies (2%), 1 Nissen fundoplication procedure (1%), 1 removal of the adrenal cyst (1%) and 3 concomitant splenectomies and cholecystectomies (2.9%). There were 3 technical conversions to multiport laparoscopy, but no conversion to open technique. Complications were observed in 5 patients (4.9%). Average operation time was 79 min (SD=40), average hospitalization time 2.4 day (SD=1.4). Conclusions. Laparoscopic single incision technique is a safe method and can be used as a reasonable alternative to multiport laparoscopy in different minimally invasive procedures especially in young patients to whom an excellent cosmetic effect is particularly important.
Źródło:
Polish Journal of Surgery; 2013, 85, 2; 73-77
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wpływ kurkuminy na uszkodzenia DNA indukowane mutagennym składnikiem żywności (heterocykliczną aminą aromatyczną) wlimfocytach pacjentów z nowotworem jelita grubego
Influence of curcumin on DNA damage induced with food mutagen (heterocyclic aromatic amine) in lymphocytes isolated from colorectal cancer patients
Autorzy:
Cierniak, Agnieszka
Łabno, Anna
Winiarski, Marek
Dembiński, Marcin
Budzyński, Piotr
Kalemba-Drożdż, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/970203.pdf
Data publikacji:
2017
Wydawca:
Krakowska Akademia im. Andrzeja Frycza Modrzewskiego
Tematy:
kurkumina
uszkodzenia DNA
PhIP
rak jelita grubego
chemoprewencja
curcumin
DNA damage
colorectal cancer
chemoprevention
Opis:
Żywność zawiera potencjalnie mutagenne substancje, takie jak PhIP, heterocykliczna amina aromatyczna powstająca podczas obróbki cieplnej mięsa, jak również substancje mogące działać w sposób ochronny poprzez m.in. modulowanie odpowiedzi antyoksydacyjnej i przeciwzapalnej, jak np. kurkumina, która jest obecna w kurkumie i mieszance curry. Materiał i metody: W przedstawionych badaniach analizowano rolę PhIP i kurkuminy na uszkodzenia DNA w limfocytach izolowanych z krwi pacjentów z rakiem jelita grubego. Limfocyty osób z rakiem jelita grubego (10 pacjentów) oraz zdrowych (kontrola, 6 osób) traktowano PhIP i/lub kurkuminą, następnie poziom uszkodzeń DNA porównano metodą kometową. Wyniki: Wstępne wyniki sugerują, że limfocyty chorych na nowotwór jelita grubego mają większe podstawowe uszkodzenia DNA niż te od osób zdrowych. Uszkodzenia wywoływane PhIP są liniowo zależne od zastosowanej dawki i mogą być zredukowane w obecności kurkuminy (zwłaszcza w stężeniu do 5 μM). Wnioski: Dane wskazują, że kurkumina może wywierać działanie ochronne przed uszkodzeniami DNA indukowanymi mutagenem obecnym w żywności.
Food contains substances that are potentially mutagens such as PhIP, heterocyclic aromatic amine, produced during heat treatment of meat, as well as substances that may act in protective manner, inter alia by modulating the antioxidant and anti-infl ammatory response, such as curcumin, which is present in turmeric and curry. Material and methods: This study investigated the effect of PhIP and curcumin on DNA damage in lymphocytes isolated from the blood of colorectal cancer patients. Lymphocytes from individuals diagnosed with colorectal cancer (N=10) and healthy individuals (control, N=6) were treated with PhIP or/and curcumin, followed by analysis of DNA damage using single cell gel electrophoresis (comet assay). Results: Preliminary results suggest that lymphocytes of patients with colorectal cancer have a greater baseline DNA damage than those from healthy individuals. PhIP-induced DNA damage is dose-dependent and can be reduced in the presence of curcumin, especially at low concentration (up to 5 μM). Conclusions: The data show that curcumin may exert a protective effect against DNA damage induced by mutagens present in food.
Źródło:
Państwo i Społeczeństwo; 2017, 4; 24-40
1643-8299
2451-0858
Pojawia się w:
Państwo i Społeczeństwo
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Early results of liver resection using laparoscopic technique
Autorzy:
Stranek, Maciej
Pędziwiatr, Michał
Radkowiak, Dorota
Zychowicz, Anna
Budzyński, Piotr
Major, Piotr
Budzyński, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1394071.pdf
Data publikacji:
2016
Wydawca:
Index Copernicus International
Tematy:
laparoscopy
liver resection
liver metastases
Opis:
The aim of the study was to present early outcomes of liver resection using laparoscopic technique. Material and methods. Retrospective analysis of patients who underwent liver resection using laparoscopic method was conducted. The analyzed group included 23 patients (11 women and 12 men). An average patient age was 61.3 years (37 – 83 years). Metastases of the colorectal cancer to the liver were the cause for qualification to the procedure of 15 patients, metastasis of breast cancer in 1 patient and primary liver malignancy in 5 patients. The other 2 patients were qualified to the liver resection to widen the surgical margins due to gall-bladder cancer diagnosed in the pathological assessment of the specimen resected during laparoscopic cholecystectomy, initially performed for other than oncology indications. Results. Hemihepatectomy was performed in 11 patients (9 right and 2 left), while the other 12 patients underwent minor resection procedures (5 metastasectomies, 4 nonanatomical liver resections, 1 bisegmentectomy, 2 resections of the gall-bladder fossa). An average duration of the surgical procedure was 275 minutes 65 – 600). An average size of the resected tumors was 28 mm (7 – 55 mm). In three cases conversion to laparotomy occurred, caused by excessive bleeding from the liver parenchyma. Postoperative complications were found in 4 patients (17.4%). Median hospitalization duration was 6 days (2 – 130 days). One patient (4.3%) was rehospitalized due to subhepatic abscess and required reoperation. Histopathology assessment confirmed radical resection (R0) in all patients in our group. Conclusion. Laparoscopic liver resections seem to be an interesting alternative in the treatment of focal lesions in the liver.
Źródło:
Polish Journal of Surgery; 2016, 88, 1; 20-25
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wczesne wyniki resekcji wątroby techniką laparoskopową
Autorzy:
Stranek, Maciej
Pędziwiatr, Michał
Radkowiak, Dorota
Zychowicz, Anna
Budzyński, Piotr
Major, Piotr
Budzyński, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1394089.pdf
Data publikacji:
2016
Wydawca:
Index Copernicus International
Tematy:
laparoskopia
resekcja wątroby
przerzuty do wątroby
Opis:
Celem pracy było przedstawienie wczesnych wyników resekcji wątroby techniką laparoskopową. Materiał i metodyka. Przeprowadzono retrospektywną analizę chorych, u których wykonano resekcję wątroby sposobem laparoskopowym. Do analizowanej grupy włączono 23 chorych (11 kobiet i 12 mężczyzn). Średni wiek chorych wyniósł 61,3 lat (37-83 lat). U 15 chorych powodem kwalifikacji do zabiegu były przerzuty do wątroby raka jelita grubego, u 1 przerzut raka sutka, u 5 chorych pierwotny nowotwór wątroby. Pozostałych 2 chorych zakwalifikowano do resekcji wątroby w celu poszerzenia marginesu operacyjnego z powodu raka pęcherzyka żółciowego rozpoznanego w trakcie oceny patomorfologicznej preparatu po laparoskopowej cholecystektomii, pierwotnie wykonanej ze wskazań innych niż onkologiczne. Wyniki. U 11 chorych wykonano hemihepatektomię (9 prawostronnych i 2 lewostronne), u pozostałych 12 chorych mniejsze zabiegi resekcyjne (5 metastazektomię, 4 nieanatomiczne resekcje wątroby, u 1 bisegmentektomię, 2 resekcje łożyska pęcherzyka żółciowego). Średni czas zabiegu wyniósł 275 min (65-600 min). Średnia wielkość usuniętych guzów wyniosła 28 mm (7-55 mm). W trzech przypadkach wystąpiła konieczność konwersji do laparotomii spowodowana nadmiernym krwawieniem z miąższu wątroby. Powikłania pooperacyjne stwierdzono u 4 chorych (17,4%). Mediana czasu hospitalizacji wyniosła 6 dni (2 – 130 dni). Jeden chory (4,3%) został ponownie rehospitalizowany z powodu ropnia podwątrobowego i wymagał ponownej operacji. U wszystkich chorych w naszej grupie ocena histopatologiczna potwierdziła radykalność zabiegu (R0). Wniosek. Laparoskopowe resekcje wątroby wydają się być interesującą alternatywą dla leczenia zmian ogniskowych w wątrobie.
Źródło:
Polish Journal of Surgery; 2016, 88, 1; 33-43
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Endoscopic Insertion Of A Self-Expandable Stent Combined With Laparoscopic Rinsing Of Peritoneal Cavity As A Method For Staple Line Leaks Treatment In Patients Post Laparoscopic Sleeve Gastrectomy
Autorzy:
Matłok, Maciej
Major, Piotr
Pędziwiatr, Michał
Winiarski, Marek
Budzyński, Piotr
Małczak, Piotr
Hynnekleiv, Leif
Budzyński, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1395616.pdf
Data publikacji:
2015-05-01
Wydawca:
Index Copernicus International
Tematy:
bariatric surgery
laparoscopic sleeve gastrectomy
post-bariatric surgery complications
staple line leaks
Opis:
Currently, laparoscopic sleeve gastrectomy is one of bariatric surgeries most commonly performed in the world. The most frequent complications of surgeries of this type, with the highest mortality rate, include bleeding into the GI tract and peritoneal cavity, and sleeve staple line leaks. These severe complications prolong the hospital stay, and often are a cause of patient’s death. While in a case of bleeding the procedure appears to be obvious, so far no uniform and standard guidelines have been established for the group of patients with staple line leaks. The aim of the study was to report results of treatment for staple line leaks following laparoscopic sleeve gastrectomy with a laparoscopic procedure and simultaneous endoscopic insertion of a self-expandable stent. Material and methods. 152 laparoscopic sleeve gastrectomies were performed from April 2009 to December 2014. The BMI median was 46.9, and the age median was 42 years. Staple line leaks developed in 3 out of 152 people (1.97%). All patients who developed this complication were included in the study. The treatment involved laparoscopic revision surgery with simultaneous endoscopic insertion of a self-expandable stent (Boston Scientific, Wallflex Easophageal Stent, 150×23 mm) into the gastric stump during gastroscopy. Results. Leaks following laparoscopic sleeve gastrectomy were diagnosed on day 5 after the procedure, on average. Intervention consisting of laparoscopy and endoscopic insertion of a self-expandable stent was initiated within 14 hours of diagnosing the leak, on average. The mean time for which the stent was kept was 5 weeks (4–6 weeks). Stenting proved to be fully effective in all patients, where after discharging home, a cutaneous fistula, periodically (every 2-3 weeks) discharging several millilitres of matter, persisted in one patient. The mean time for the leak healing in 2 patients, in whom the described method was successful in treatment of this complication, was 37 days. No patient died in the perioperative or follow-up period. Conclusions. The proposed method for treatment of staple line leaks following laparoscopic sleeve gastrectomy by combined laparoscopic rinsing and draining of the peritoneal cavity and endoscopic insertion of a self-expandable stent is an interesting and worth recommending method for treatment of this complication.
Źródło:
Polish Journal of Surgery; 2015, 87, 5; 238-244
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The usefulness of the Mannheim Peritonitis index score in assessing the condition of patients treated for peritonitis
Autorzy:
Budzyński, Piotr
Dworak, Jadwiga
Natkaniec, Michał
Pędziwiatr, Michał
Major, Piotr
Migaczewski, Marcin
Matłok, Maciej
Budzyński, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1395648.pdf
Data publikacji:
2015-06-01
Wydawca:
Index Copernicus International
Tematy:
peritonitis
mortality
Mannheim Peritonitis Index (MPI)
Opis:
The aim of the study was to verify the Mannheim Peritonitis Index (MPI) suitability to determine the probability of death among patients in Polish population operated due to peritonitis and to assess the possibility of using the Index to determine the risk of postoperative complications, relaparotomy and need for postoperative hospitalization in intensive care unit. Material and methods. Retrospective analysis covered 168 patients (M: F = 83: 85, mean age = 48.45 years, SD ± 22.2) treated for peritonitis. The MPI score was calculated for each patient. According to MPI results, patients were divided to the appropriate groups (<21, 21‑29, > 29) and within analyzed. The statistical analysis used Chi-square, Mann Withney U and Kolmogorov-Smirnov test. The best cut-off point for MPI was calculated on the basis of ROC analisys. Results. Mortality in the study group was 13.1%. In groups <21, 21‑29 and > 29 points according to MPI mortality was 1.75%, 28.13% and 50% respectively, the difference was statistically significant (p = 0.0124). Significant differences were observed in mortality depending on the diagnosis. Based on the ROC curve the cut-off point was identified as 32 with an accuracy of 85.9% and AUC = 81%. There has been a significant correlation between the MPI count and and the occurrence of: cardio-respiratory failure, acidosis, electrolyte imbalance, surgical wound complications, the need for treatment in the intensive care unit after surgery. Conclusions. The MPI is a simple and effective predictor of death among patients operated due to peritonitis. It can also provide assistance in assessing the risk of postoperative complications and the need for treatment in the intensive care unit.
Źródło:
Polish Journal of Surgery; 2015, 87, 6; 301-306
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Impact of bariatric surgery on non-alcoholic fatty liver disease
Autorzy:
Major, Piotr
Pędziwiatr, Michał
Rubinkiewicz, Mateusz
Stanek, Maciej
Głuszewska, Anna
Pisarska, Magdalena
Małczak, Piotr
Budzyński, Andrzej
Budzyński, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1393188.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
non-alcoholic fatty liver disease
bariatric surgery
morbid obesity
Opis:
Introduction; p to 300 million people have the body mass index (BMI) greater than 30 kg/m2. Obesity is the cause of many serious diseases, such as type 2 diabetes, hypertension, and non-alcoholic fatty liver disease (NAFLD). Bariatric surgery is the only effective method of achieving weight loss in patients with morbid obesity. Objectives: The aim of the study was to assess the impact of bariatric surgery on non-alcoholic fatty liver disease in patients operated on due to morbid obesity. Material and Methods: We included 20 patients who were qualified for bariatric procedures based on BMI > 40 kg/ m2 or BMI > 35kg/m2 with the presence of comorbidities. The average body weight in the group was 143.85kg, with an average BMI of 49.16kg/m2. Before the procedure, we evaluated the severity of non-alcoholic fatty liver disease in each patient using the Sheriff-Saadeh ultrasound scale. We also evaluated the levels of liver enzymes. Follow-up evaluation was performed twelve months after surgery. Results: Twelve months after surgery, the average weight was 102.34 kg. The mean %WL was 33.01%, %EWL was 58.8%, and %EBMIL was 61.37%. All patients showed remission of fatty liver disease. Liver damage, evaluated with ultrasound imaging, decreased from an average of 1.85 on the Sheriff-Saadeh scale, before surgery, to 0.15 twelve months after surgery (p < 0.001). As regards liver enzymes, the level of alanine aminotransferase decreased from 64.5 (U/l) to 27.95 (U/l) (p < 0.001), and the level of aspartate aminotransferase decreased from 54.4 (U/l) to 27.2 (U/l). Conclusions: Bariatric procedures not only lead to a significant and lasting weight loss, but they also contribute to the reduction of fatty liver disease and improve liver function.
Źródło:
Polish Journal of Surgery; 2017, 89, 2; 1-4
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Elective laparoscopic cholecystectomy – is it safe in the hands of residents during training?
Autorzy:
Kisielewski, Michał
Pędziwiatr, Michał
Pisarska, Magdalena
Major, Piotr
Rubinkiewicz, Mateusz
Matłok, Maciej
Migaczewski, Marcin
Budzyński, Piotr
Budzyński, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1394419.pdf
Data publikacji:
2015
Wydawca:
Index Copernicus International
Tematy:
laparoscopic cholecystectomy
resident education
conversion of operator
Opis:
The aim of the study was to assess safety of elective laparoscopic cholecystectomy (LC) performed by residents that are undergoing training in general surgery. Material and methods. A retrospective analysis was conducted on 330 patients operated electively due to cholelithiasis. Patients with acute cholecystitis, choledocholithiasis, undergoing cholecystectomy as a part of more extensive operation and patients with gall-bladder cancer were excluded. Group 1 included patients operated by resident, group 2 – by specialist. Duration of operation, mean blood loss, number of major complications, number of conversions to the open technique and conversions of the operator, reoperations and length of hospital stay were analyzed. Results. Mean operative time overall was 81 min (25 – 170, SD±28.6) and 71 min (30-210, SD±29.1) in groups 1 and 2 respectively (p=0.00009). Mean blood loss in group 1 was 45±68.2 ml and in group 2 – 41±73.4 ml (p=0.23). Six major complications has occurred (1.81%) – 2 (2%) in group 1 and 4 (1.7%) in group 2. 18 cases (15.5%) of conversion of the operator occurred in group 1, and 6 cases (2.6%) of conversion of the operator happened in group 2. Average LOS was 1.9 days in group 1 and 2.3 days in group 2 (p=0.03979). Conlcusions. Elective LC performed by a supervised resident is a safe procedure. Tactics of “conversion of operator” allowed to prevent major complications. Longer LC by residents is natural during the learning curve. Modifications of residency program in the field of laparoscopy may increase its accessibility.
Źródło:
Polish Journal of Surgery; 2015, 87, 9; 429-433
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Laparoscopic cholecystectomy in the treatment of gallbladder polypoid lesions – 15 years of experience
Autorzy:
Matłok, Maciej
Migaczewski, Marcin
Major, Piotr
Pędziwiatr, Michał
Budzyński, Piotr
Winiarski, Marek
Ostachowski, Mateusz
Budzyński, Andrzej
Rembiasz, Kazimierz
Powiązania:
https://bibliotekanauki.pl/articles/1396486.pdf
Data publikacji:
2013-11-01
Wydawca:
Index Copernicus International
Tematy:
gall-bladder polyps
laparoscopic cholecystectomy
gall-bladder cancer
gall-bladder ultrasound
Opis:
Due to the constant increase of public health awareness and widespread “cancerophobia”, the progressively larger number of incidentally diagnosed gall-bladder polyps became the source of anxiety, which leads patients and physicians to undertake therapeutic decisions, despite the absence of symptoms. The majority of gall-bladder polyps are benign. It is estimated that only 3 to 5% of polyps are malignant. Currently, there is lack of randomized control trials based on which the clear-cut criteria of qualification of patients with gall-bladder polyps for surgical procedure can be created. The aim of the study was to analyze gall-bladder polyps in patients who underwent laparoscopic cholecystectomy in the 2nd Department of General Surgery, Jagiellonian University Collegium Medicum. Material and methods. The retrospective study was conducted on 5369 patients who underwent laparoscopic cholecystectomy in the 2nd Department of General Surgery, Jagiellonian University Collegium Medicum with special attention to 152 (2.8%) patients in whom gall-bladder polyps were diagnosed preoperatively. Qualification criteria for surgery, surgical treatment results, and histopathological examination results were also analyzed. Results. Amongst the 5369 patients qualified for laparoscopic cholecystectomy, 152 (2.8%) were diagnosed with gall-bladder polyps during the preoperative ultrasound examinations. Postoperative histopathological examinations of 41 (27%) patients confirmed the presence of gall-bladder polyps. In 102 (67%) patients, only gall-stones were diagnosed without previously described polyps during the ultrasound examination. Analysis of the histopathological examination results revealed the presence of benign lesions in 35 (23.35%) patients. In 5 (3%) patients the presence of an adenoma, and in one (0.65%) the presence of adenocarcinoma were confirmed. Conclusions. Based on the conducted study and previous personal experience in the treatment of patients with gall-bladder polyps, we believe that due to the potential risk of neoplastic transformation, patients with polyps larger than 10 mm in diameter and polyps of proven rapid growth should be qualified for laparoscopic cholecystectomy. Indications for surgical treatment also seem reasonable in case of patients with present polyps and coexisting right upper quadrant pain, even though the above-mentioned is connected with gall-bladder deposits.
Źródło:
Polish Journal of Surgery; 2013, 85, 11; 625-629
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wpływ operacji bariatrycznych na przebieg niealkoholowej stłuszczeniowej choroby wątroby
Autorzy:
Major, Piotr
Pędziwiatr, Michał
Rubinkiewicz, Mateusz
Stanek, Maciej
Głuszewska, Anna
Pisarska, Magdalena
Małczak, Piotr
Budzyński, Andrzej
Budzyński, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1393201.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
niealkoholowa stłuszczeniowa choroba wątroby
chirurgia bariatryczna
otyłość olbrzymia
Opis:
Wstęp: prawie 300 milionów ludzi na świecie BMI przekracza 30 (kg/m2). Otyłość jest przyczyną wielu poważnych schorzeń, takich jak cukrzyca typu 2, nadciśnienie tętnicze czy niealkoholowe stłuszczenie wątroby. Chirurgia bariatryczna jest jedyną efektywną metodą uzyskania redukcji masy ciała u pacjentów z otyłością olbrzymią. Cele: Celem tej pracy jest ocena wpływu chirurgii bariatrycznej na niealkoholowe stłuszczenie wątroby u pacjentów operowanych z powodu otyłości olbrzymiej. Materiał i metodologia: Włączyliśmy 20 pacjentów zakwalifikowanych do zabiegu bariatrycznego z BMI >40 kg/m2 lub BMI >35kg/m2 z współwystępującymi chorobami towarzyszącymi. Średnia masa ciała badanej grupy wynosiła 143,85 kg, ze średnim BMI 49,16 kg/m2. Przed zabiegiem dokonano oceny stopnia niealkoholowego stłuszczenia wątroby przy użyciu skali Sherifa Saadeha podczas badania ultrasonograficznego. Dokonaliśmy także oceny stężeń enzymów wątrobowych. Obserwację i wizyty kontrolne kontynuowano do 12 miesięcy po zabiegu. Wyniki: Dwanaście miesięcy po operacji średnia masa ciała badanej grupy wynosiła 102,34 kg. WL wyniosło średnio 33,0%, EWL 58,8%, a EBMIL 61,37%. U wszystkich pacjentów zaobserwowano remisję stłuszczenia wątroby. Uszkodzenie wątroby, ocenione przy użyciu ultrasonografii, zmniejszyło się ze średnio 1,85 pkt w skali Sherifa Saadeha przed zabiegiem do 0,15 pkt po 12 miesiącach (p=0,00). Poziomy enzymów wątrobowych zmalały z 64,5 (U/l) do 27,95 (U/l) dla ALT (p=0,00) oraz z 54,4 (U/l) do 27,2 (U/l) dla AST. Wnioski: rocedury bariatryczne nie tylko pozwalają na znaczącą oraz trwała utratę masy ciała, ale także przyczyniają się do zmniejszenia stłuszczenia wątroby oraz poprawy jej funkcjonowania.
Źródło:
Polish Journal of Surgery; 2017, 89, 2; 1-4
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Randomized Clinical Trial to Compare the Effects of Preoperative Oral Carbohydrate Loading versus Placebo on Insulin Resistance and Cortisol Level after Laparoscopic Cholecystectomy
Autorzy:
Pędziwiatr, Michał
Pisarska, Magdalena
Matłok, Maciej
Major, Piotr
Kisielewski, Michał
Wierdak, Mateusz
Natkaniec, Michał
Budzyński, Piotr
Rubinkiewicz, Mateusz
Budzyński, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1394369.pdf
Data publikacji:
2015
Wydawca:
Index Copernicus International
Tematy:
laparoscopic cholecystectomy
insulin resistance
preoperative carbohydrate loading
perioperative care
Opis:
Postoperative insulin resistance, used as a marker of stress response, is clearly an adverse event. It may induce postoperative hyperglycemia, which according to some authors can increase the risk of postoperative complications. One of the elements of modern perioperative care is preoperative administration of oral carbohydrate loading (CHO-loading), which shortens preoperative fasting and reduces insulin resistance. The aim of the study is to establish the influence of CHO-loading on the level of insulin resistance and cortisol in patients undergoing elective laparoscopic cholecystectomy. Material and methods. Patients were randomly allocated to one of 2 groups. The intervention group included 20 patients who received CHO-loading (400 ml Nutricia pre-op®) 2 hours prior surgery. The control group received a placebo (clear water). In every patient blood samples were taken 2 hours prior to surgery, immediately after surgery, and on the 1st postoperative day. Levels and changes in glucose, cortisol and insulin resistance were analyzed in both groups. Results. Although there were differences in the levels of cortisol, insulin, and insulin resistance, no statistically significant differences were observed between groups in every measurement. The length of stay and postoperative complications were comparable in both groups. Conclusions. We believe that CHO-loading is not clinically justified in case of laparoscopic cholecystectomy. No effect on the levels of glucose, insulin resistance and cortisol was observed. Even though such procedure is safe, in our opinion there is no clinical benefit from CHO-loading prior to laparoscopic cholecystectomy.
Źródło:
Polish Journal of Surgery; 2015, 87, 8; 402-408
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
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