Autor: Bojarojc, B. - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Leucocyte acid phosphatase and selected haematological indices in BLV infected cows
Autorzy:: Kaczmarczyk, E
Czarnik, U.
Bojarojc, B.
Walawski, K.
Powiązania:: https://bibliotekanauki.pl/articles/2043884.pdf
Data publikacji:: 1999
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: hematological index
cow
polymorphism
blood leucocyte
acid phosphatase
cattle
lysosomal enzyme
leucocyte
enzootic bovine leukemia
Źródło:: Journal of Applied Genetics; 1999, 40, 2; 93-101
1234-1983
Pojawia się w:: Journal of Applied Genetics
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Tumor necrosis factor - alpha (TNFalpha) gene polymorphism and expression of membrane - bound TNFalpha protein on CD11bplus and IgMplus cells in cows naturally infected with bovine leukemia virus
Autorzy:: Bojarojc-Nosowicz, B.
Kaczmarczyk, E.
Stachura, A.
Kubinska, M.
Powiązania:: https://bibliotekanauki.pl/articles/31645.pdf
Data publikacji:: 2015
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:: The aim of this study was to determine whether SNP at position -824 (promoter region) of the TNFα gene significantly differentiates the size of IgM+, CD5+ and CD11b+ cell subpopulations and affects the expression of membrane-bound TNFα protein (mTNFα) on these cells and their susceptibility to BLV infections. In this study, significant differences were determined for the first time between TNFα genotypes and the percentage of cells with the CD11b+TNFα+p24+ immunophenotype. Furthermore, greater expansion of lymphocytes with the IgM+TNFα+p24+ immunophenotype was reported in cows with the G/G genotype than in A/A homozygotes. Cells with the above immunophenotype were more frequently observed in cows with persistent leukocytosis than in aleukemic cattle. Our results suggest that polymorphism of the TNFα -824 A>G gene and mTNFα protein expression play an important role in the pathogenesis of enzootic bovine leukosis.
Źródło:: Polish Journal of Veterinary Sciences; 2015, 18, 3
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Polymorphism in the promoter region of the tumor necrosis factor-alpha gene in cattle herds naturally infected and uninfected with the Bovine Leukemia Virus
Autorzy:: Bojarojc-Nosowicz, B.
Kaczmarczyk, E.
Stachura, A.
Kotkiewicz, M.
Powiązania:: https://bibliotekanauki.pl/articles/31844.pdf
Data publikacji:: 2011
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:: The objective of this study was to describe and compare the genetic structure (TNF-α-position 824) of dairy cattle herds infected and not infected with the bovine leukemia virus (BLV). The results of the present study indicate that BLV-positive herds were characterized by similar genetic structure (TNF-α-824A/G). The genetic equilibrium in these herds was preserved, but a tendency to increased frequency of G/G homozygotes was found. The genetic structure of the healthy herd differed considerably from that of leukemic herds.
Źródło:: Polish Journal of Veterinary Sciences; 2011, 14, 4
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Polymorphism and expression of the tumor necrosis factor receptor II gene in cows infected with the bovine leukemia virus
Autorzy:: Stachura, A.
Brym, P.
Bojarojc-Nosowicz, B.
Kaczmarczyk, E.
Powiązania:: https://bibliotekanauki.pl/articles/32553.pdf
Data publikacji:: 2016
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:: A single T>C nucleotide polymorphism (rs42686850) of bovine tumor necrosis factor receptor type II gene (TNF-RII) is located within a sequence with allele-specific affinity to bind E2F transcription factors, considered pivotal in the regulation of cell cycle and cell proliferation. The objective of the study was to determine the effect of this SNP and BLV infection on the TNF-RII gene expression at the mRNA and protein levels in peripheral blood mononuclear cells (PBMC). We noted that analyzed TNF-RII gene polymorphism influenced the expression of the TNF-RII gene at the mRNA level but only in BLV-positive cows. Concurrently, no statistically significant association was found between gene polymorphism and TNF-RII expression at the protein level. However, we found a significant effect of BLV infection status on the amount of TNF-RII mRNA and the percentage of PBMC expressing TNF-RII. These results show an unclear effect of considered T>C polymorphism on TNF-RII gene expression in bovine leukocytes and they suggest the involvement of BLV in modifying the TNF-RII expression in BLV-infected cows potentially implying the EBL (Enzootic Bovine Leukosis) associated pathogenesis.
Źródło:: Polish Journal of Veterinary Sciences; 2016, 19, 1
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki

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