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Tytuł:
Banganarti and Selib in the 2013/2014 and 2014/2015 seasons with Appendix 1: Pottery from Selib. Preliminary report (2013/2014 and 2014/2015 seasons), Appendix 2: Osteoarchaeological analyses of skeletal material from Selib 1 and Banganarti (2013/2014 and 2014/2015 seasons)
Autorzy:
Żurawski, Bogdan
Cedro, Aneta
Bury, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/1706358.pdf
Data publikacji:
2016
Wydawca:
Uniwersytet Warszawski. Wydawnictwa Uniwersytetu Warszawskiego
Tematy:
Nubia
Banganarti
Selib
Meroitic settlement
church architecture
St Menas
St Thecla
pottery
liturgical vessels
oil lamps
Northern Building
archaeology of the Middle Nile
conservation
anthropology
Opis:
The Polish archaeological project excavating at the Nubian sites of Banganarti and Selib concentrated on uncovering domestic architecture: the northeastern and southwestern districts at medieval Christian Banganarti and selected houses of Meroitic date at Selib 2. The conservation and restoration program put the finishing touches on the Raphaelion church in Banganarti and did substantial work on the remains of the earlier churches. The oldest church from Selib 1 was investigated and dated to the 6th–7th century based on a study of a well stratified ceramic assemblage. Pottery from the northern and southern refuse dumps ranged in date from the 9th to the 12th/13th century. A group of liturgical vessels, containing mostly small juglets and chalices, was distinguished in this assemblage. Exploration of the earlier Northern Building revealed pottery contemporaneous with the earliest phase of the church on site. Anthropological research was carried out on skeletal remains from the medieval cemeteries of Selib 1 and from individual graves at Banganarti. The results of ceramic studies and of the anthropological examination are reported in separate appendices to the main report.
Źródło:
Polish Archaeology in the Mediterranean; 2016, 25; 349-402
1234-5415
Pojawia się w:
Polish Archaeology in the Mediterranean
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
New Computer Method of Derivative Thermal Express Analysis of Cast Iron for Operational Prediction of Quality of Melts and Castings
Autorzy:
Zakharchenko, Edvard
Sirenko, Ekaterina
Goncharov, Alexander
Bogdan, Alexander
Burbelko, Andriy
Kawalec, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/106953.pdf
Data publikacji:
2019
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Wydawnictwo AGH
Tematy:
derivative thermal express-analysis
reference and analyzed cooling curve similarity criterion
gray iron
white iron,
immersion sample cup
Opis:
This method is based on the determination of similarity criterion Z as the average temperature difference between the reference and analyzed curves in the solidification region. The purpose of this work is to describe the thermal express-analysis (TDA) device created by us and the substantiation of the reliability and sensitivity of the results of the new method, including the definition of a two-sided confidence interval using Student’s t-test. The error of the method was determined with the Student’s criterion taken into account. The high sensitivity of the method to the metallurgical prehistory of the gray and white cast iron melts was confirmed. The method has been successfully tested under laboratory and experimental-industrial conditions on induction melting cast iron. The new method uses a disposable environmentally friendly submersible steel sampler with a heat-resistant coating inside and out. The method allows for the quick adaptation to the conditions of specific foundries (especially with the frequent changes of classes and types of cast iron) due to replenishing the database of the reference samples. The basic features of the new method are its universality, self-adaptability, speed, relative simplicity, and high sensitivity to the metallurgical prehistory of molten iron.
Źródło:
Journal of Casting & Materials Engineering; 2019, 3, 2; 31-42
2543-9901
Pojawia się w:
Journal of Casting & Materials Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
May metallic biomaterials used for orthopedic implants promote cancer processes? : preliminary trasriptomics research on human articular chondrocytes.
Autorzy:
Walkowiak-Przybyło, Magdalena
Walczyńska, Marta
Kamińska, Marta
Komorowski, Piotr
Walkowiak, Bogdan
Powiązania:
https://bibliotekanauki.pl/articles/1844950.pdf
Data publikacji:
2020
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
biomaterials
implants
cancer
biomateriały
implanty
onkologia
Źródło:
Engineering of Biomaterials; 2020, 23, 158 spec. iss.; 32
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Alergia a stres oksydacyjny
Allergy and Oxidative Stress
Autorzy:
Twardoch, Magdalena A.
Lodwich, Magdalena
Mazur, Bogdan
Powiązania:
https://bibliotekanauki.pl/articles/1036585.pdf
Data publikacji:
2016
Wydawca:
Śląski Uniwersytet Medyczny w Katowicach
Tematy:
stres oksydacyjny
reaktywne formy tlenu
astma oskrzelowa
alergiczny nieżyt nosa
atopowe zapalenie skóry
atopic dermatitis
oxidative stress
reactive oxygen species
bronchial asthma
allergic rhinitis
Opis:
Oxygen is a biogenic element which determines the course of basic biochemical processes to ensure the survival of the cell. Unfortunately, in particular circumstances, the highly reactive oxygen species (ROS) may cause a toxic effect on the body. Small amounts of ROS are essential for the proper functioning of cells, however, the excessive production of them, which transcend the effectiveness of antioxidant systems – defined as oxidative stress – promotes structural and functional disorders of cells and tissues. Nowadays, the significant participation of oxidative stress is increasingly more frequently indicated in the course and/or etiology of chronic inflammatory diseases, which include atopic diseases such as bronchial asthma, atopic dermatitis, or allergic rhinitis.
Tlen jako pierwiastek biogenny warunkuje przebieg podstawowych procesów biochemicznych gwarantujących przeżycie komórki. Niestety, w szczególnych warunkach wysoce reaktywne formy tlenu (RFT) mogą wywierać toksyczny efekt na organizm. W niewielkich ilościach RFT są niezbędne do prawidłowego funkcjonowania komórki, jednak ich nasilone wytwarzanie, przekraczające skuteczność działania systemów antyoksydacyjnych, określane mianem stresu oksydacyjnego, sprzyja zaburzeniom struktury i funkcji komórek oraz tkanek. Współcześnie coraz częściej wskazuje się na istotny udział stresu oksydacyjnego w przebiegu i/lub etiologii przewlekłych chorób zapalnych, do których zalicza się m.in. choroby atopowe, takie jak astma oskrzelowa, atopowe zapalenie skóry czy alergiczny nieżyt nosa.
Źródło:
Annales Academiae Medicae Silesiensis; 2016, 70; 15-23
1734-025X
Pojawia się w:
Annales Academiae Medicae Silesiensis
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The essence and scope of competitiveness of healthcare organisations in Poland
Autorzy:
Sikora, Tomasz
Kanecki, Krzysztof
Sikora, Agnieszka
Bogdan, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/2124315.pdf
Data publikacji:
2021
Wydawca:
Uniwersytet w Białymstoku. Wydawnictwo Uniwersytetu w Białymstoku
Tematy:
competitiveness
healthcare organisation
patient care
Opis:
Purpose – The paper presents an analysis of the broadly defined essence of competitiveness in the healthcare sector and the closely related issue of the competitiveness of healthcare organisations accounting for the specifics of key types of competition in healthcare. The objective of the paper is to demonstrate that the essence of competition between healthcare organisations is represented by a better use of resources by some enterprises and enhanced cost efficiency in the conditions of the increased demand for top quality services. Research method – The research methodology applied in the study was literature research, the analysis of available empirical research results and of the laws and regulations applicable to the healthcare market. The analysis focused on the specifics of the Polish healthcare market and the ensuing conse-quences for the competitiveness of healthcare organisations. Results – The results of the analysis show how complex the issue of competitiveness of healthcare organisations is and how relevant it is for the increase of quality, availability, and innovativeness of healthcare for patients.
Źródło:
Optimum. Economic Studies; 2021, 4(106); 18-29
1506-7637
Pojawia się w:
Optimum. Economic Studies
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The influence of holmium on catalytic properties of Fe or Cu-modified vermiculites
Autorzy:
Samojeden, Bogdan
Grzybek, Teresa
Kowal, Joanna
Szymaszek, Agnieszka
Jabłońska, Magdalena
Gläser, Roger
Motak, Monika
Powiązania:
https://bibliotekanauki.pl/articles/109844.pdf
Data publikacji:
2019
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
selective catalytic reduction
deNOx
holmium
vermiculite
Opis:
Natural layered clay, vermiculite, was modified and tested as catalyst for the selective catalytic reduction of NOx with ammonia (NH3-SCR). Its modification included the application of the blowing agent (azodicarbonamide), acid treatment and pillaring with Al2O3. Active phase (transition metals: Cu or Fe) was introduced via impregnation. The obtained materials were characterized by N2 sorption (texture), XRD (structure), DR-UV-Vis (oxidation state and aggregation of the active phase), H2-TPR (reducibility of the active phase), in situ DRIFTS (types of adsorbed species due to contact of the sample NH3) and NH3-TPD (type/strength of the acidic sites). The initial modification procedures (treatment with azodicarboamide) resulted in the increase of specific surface area of vermiculite. The introduction of transition metal ions provided a significant amount of acidic sites. The promoting impact of holmium was confirmed by the increased strength of the sites. The highest catalytic activity was exhibited by the sample Fe-containing vermiculite and doped with Ho.
Źródło:
Physicochemical Problems of Mineral Processing; 2019, 55, 6; 1484-1495
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zadłużenie jednostek samorządu terytorialnego jako uwarunkowanie absorpcji środków unijnych
Indebtedness of local government units as a determinant for the absorption of EU funds
Autorzy:
Miszczuk, Magdalena
Kawałko, Bogdan
Powiązania:
https://bibliotekanauki.pl/articles/1832083.pdf
Data publikacji:
2020-04-30
Wydawca:
Katolicki Uniwersytet Lubelski Jana Pawła II. Towarzystwo Naukowe KUL
Tematy:
gminy
miasta
województwo lubelskie
zadłużenie
absorpcja środków unijnych
ocal government units
cities
Lublin voivodship
indebtedness
absorption of EU funds
Opis:
Celem autorów artykułu było przedstawienie badań dotyczących wpływu zadłużenia wybranych JST na pozyskiwanie środków unijnych. Dla realizacji celu przyjęto dwie hipotezy. Pierwsza zakładała, że wielkość zadłużenia JST wpływa na absorpcję środków unijnych, druga natomiast stwierdzała, że JST wyhamowują proces zadłużania się pod koniec okresu perspektywy finansowej 2007-3013, aby przygotować się do pozyskiwania środków UE w latach 2014-2020. Badaniem objęto 46 gmin województwa lubelskiego o charakterze miejsko-wiejskim (26 gmin) i miejskim (20 gmin, w tym 4 miasta na prawach powiatu). Przeprowadzona analiza nie potwierdziła hipotezy pierwszej. Druga hipoteza natomiast w pewnym stopniu jest prawdziwa, gdyż ponad połowę miast obniżyło swoje zadłużenie przed okresem nowej perspektywy UE.
The aim of the research is to outline the influence of the debt of the selected local government units on obtaining EU funds. In order to meet the objective, two hypotheses have been raised. The first one implies that the volume of the local government units’ debt has an impact on the absorption of EU funds, whereas the other hypothesis states that local government units slow down the process of indebtedness towards the end of the financial perspective in the years 2007-2013 in order to prepare for obtaining EU funds for the years 2014-2020. The examination covers 46 municipalities of the Lublin voivodship, both of urban-rural (26 municipalities) and of urban nature (20 municipalities, including four city counties). The conducted analysis has not supported the first hypothesis. The other hypothesis seems correct to some extent, since over half of the cities reduced their debts before the period of the new EU perspective.
Źródło:
Roczniki Nauk Społecznych; 2017, 45, 3; 57-72
0137-4176
Pojawia się w:
Roczniki Nauk Społecznych
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ocena wybranych parametrów równowagi oksydacyjno-antyoksydacyjnej u dzieci chorych na astmę oskrzelową i atopowe zapalenie skóry
Selected parameters of the oxidative-antioxidative balance in children with bronchial asthma and atopic dermatitis
Autorzy:
Lodwich, Magdalena
Romuk, Ewa
Echolc, Bożena
Karpe, Jacek
Machura, Edyta
Birkner, Ewa
Mazur, Bogdan
Powiązania:
https://bibliotekanauki.pl/articles/1038608.pdf
Data publikacji:
2012
Wydawca:
Śląski Uniwersytet Medyczny w Katowicach
Tematy:
astma oskrzelowa
atopowe zapalenie skóry
stres oksydacyjny
bronchial asthma
atopic dermatitis
oxidative stress
Opis:
The aim of study was to evaluate the involvent of selected parameters of oxidative-antioxidative system in children with bronchial asthma and atopic dermatitis. MATERIAL AND METHODS The research was carried out in the group of 58 children who had been diagnosed with bronchial asthma and atopic dermatitis. The children were undergoing treatment in the Alergological and Pulmonological Outpatient Clinic at the S. Szyszko Independent State Clinical Hospital No. 1 in Zabrze of the Silesian Medical University in Katowice. Periods of their outpatient treatment ranged from 1 to 16 years. To evaluate the oxidative/antioxidative balance, the activity of antioxidant enzymes was analysed. The considered enzymes were: superoxide dismutase (SOD) and its isozymes (Cu/ZnSOD), (MnSOD), glutathione peroxidase (GPx), glutathione S-transferase (GST) and catalase (CAT). To evaluate the oxidation system, fi rst the concentration of malondialdehyde (MDA) was determined in the plasma and lysate, revealing the level of lipid peroxidation. RESULT S It was established that children with bronchial asthma have a statistically signifi cant lower average activity value of glutathione peroxidase in the lysate as compared to the average value in the control group. Furthermore, children with bronchial asthma turned out to have a statistically signifi cant lower average activity value of glutathione S-transferase in the lysate as compared to the average values in children with AD. Moreover, there were no changes in the values of malondialdehyde concentration or antioxidant enzyme activity in the analysed lysate and plasma in the groups of children with bronchial asthma in respect to their age. CONCLUSION Disturbances in the oxidative-antioxidative system were observed in children suff ering from bronchial asthma and atopic dermatitis, which manifested themselves by changes in certain indicators of the antioxidative system.
Celem pracy była ocena aktywności wybranych enzymów antyoksydacyjnych we krwi dzieci chorych na astmę oskrzelową i atopowe zapalenie skóry. MATERIAŁ I METODY Badania przeprowadzono w grupie 58 dzieci, u których rozpoznano astmę oskrzelową i atopowe zapalenie skóry. Dzieci były leczone w Poradni Alergologiczno-Pulmonologicznej Samodzielnego Publicznego Szpitala Klinicznego Nr 1 im. S. Szyszko w Zabrzu. Czas leczenia ambulatoryjnego wahał się od 1 roku do 16 lat. Dla oceny systemu antyoksydacyjnego badano aktywność enzymów o właściwościach antyoksydacyjnych: dysmutazy ponadtlenkowej (SOD) i jej izoenzymów: (Cu/ZnSOD), (MnSOD), peroksydazy glutationowej (GPx), S-transferazy glutationowej (GST) oraz katalazy (CAT). Dla oceny systemu oksydacyjnego oznaczono stężenie dialdehydu malonowego (MDA), które informuje o stopniu peroksydacji lipidów. Oznaczenia zostały wykonane w osoczu i lizacie. WYNIKI Stwierdzono, że dzieci z astmą oskrzelową mają istotnie statystycznie niższą średnią wartość aktywności peroksydazy glutationowej w lizacie w porównaniu ze średnią wartością w grupie kontrolnej. Wykazano również, że dzieci z astmą oskrzelową mają istotnie statystycznie niższą średnią wartość aktywności S-transferazy glutationowej w lizacie w porównaniu ze średnią wartością u dzieci z AZS. Nie wykazano zmian w wartościach stężenia dialdehydu malonowego i aktywności enzymów antyoksydacyjnych oznaczonych w lizacie i osoczu w grupie dzieci z astmą oskrzelową oraz w grupie dzieci z AZS. WNIOSEK U dzieci chorych na astmę oskrzelową i atopowe zapalenie skóry zaobserwowano zaburzenia w układzie oksydacyjno-antyoksydacyjnym, manifestujące się zmianami w zakresie niektórych wskaźników układu antyoksydacyjnego.
Źródło:
Annales Academiae Medicae Silesiensis; 2012, 66, 1; 16-23
1734-025X
Pojawia się w:
Annales Academiae Medicae Silesiensis
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Knowledge about the COVID-19 and ways of its prevention among Medical University of Warsaw students
Autorzy:
Lewtak, Katarzyna
Poznańska, Anna
Okręglicka, Katarzyna
Kanecki, Krzysztof
Bogdan, Magdalena
Nitsch-Osuch, Aneta
Powiązania:
https://bibliotekanauki.pl/articles/2152948.pdf
Data publikacji:
2022
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
knowledge
Polska
medical students
COVID-19
SARS-CoV-2
infectious disease outbreak
Opis:
BackgroundThe aim of the study was to assess the state of knowledge of Medical University of Warsaw (MUW) students on COVID-19, modes of transmission and preventive measures.Material and MethodsThe study was conducted in October 2020. The participants were all the students attending classes at MUW – 8922 persons. All had completed the online training “Work safety and hygiene during COVID-19.” To assess their state of knowledge an online questionnaire was made available on the MUW e-learning platform. The questionnaire comprised 4 parts: (1) awareness of rules of hand hygiene, (2) medical aspects of COVID-19, (3) preventing SARS-CoV-2 infection transmission in health care facilities, and (4) preventing infection transmissions in the society.ResultsThe majority of students (93.9%) demonstrated a sufficient level of knowledge. The highest passing threshold was found on the medical programme (96.7% of students with satisfactory level of knowledge), dentistry (96.2%) and pharmacy (95.5%). The statistically significant factors that differentiated student results proved to be faculty (p < 0.001), study programme (p < 0.001), year of studies (p = 0.001), form of studies (p < 0.001). The participants most often showed full knowledge (100% correct answers in sub-area) of preventing infection transmissions in the society (93.3%) and medical aspects of COVID-19 (91.8%), less complete in terms of ways of preventing infection transmission in health care facilities (85.4%), and in particular hand hygiene rules (78.3%). All the variables characterizing academic status (study programme, faculty, year and form of studies) were statistically significant differentiating factors for students’ full knowledge in all of the 4 analyzed sub-areas, while students’ sex only in the sub-area of COVID-19 medical aspects.ConclusionsThere is a clear need for conducting systematic educational activities among students of all medical study programmes and assessing their level of knowledge in those areas that were identified as least frequently controlled, namely, hand hygiene and infection transmission in health care facilities.
Źródło:
Medycyna Pracy; 2022, 73, 5; 369-381
0465-5893
2353-1339
Pojawia się w:
Medycyna Pracy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cecha wczesności kwitnienia u łubinu białego i łubinu żółtego — podstawy genetyczne i molekularne
Early flowering traits of white lupin and yellow lupin — genetic and molecular backgrounds
Autorzy:
Książkiewicz, Michał
Plewiński, Piotr
Rychel, Sandra
Tomaszewska, Magdalena
Sawikowska, Aneta
Bielski, Wojciech
Naganowska, Barbara
Wolko, Bogdan
Powiązania:
https://bibliotekanauki.pl/articles/2199545.pdf
Data publikacji:
2019-11-30
Wydawca:
Instytut Hodowli i Aklimatyzacji Roślin
Tematy:
termin kwitnienia
wernalizacja
phenotypowanie
mapowanie genetyczne
sekwencjonowanie DNA
sekwencjonowanie RNA
Źródło:
Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin; 2019, 286; 357-360
0373-7837
2657-8913
Pojawia się w:
Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
1000 Liver Transplantations at the Department of General, Transplant and Liver Surgery, Medical University of Warsaw - Analysis of Indications and Results
Autorzy:
Krawczyk, Marek
Grąt, Michał
Barski, Krzysztof
Ligocka, Joanna
Antczak, Arkadiusz
Kornasiewicz, Oskar
Skalski, Michał
Patkowski, Waldemar
Nyckowski, Paweł
Zieniewicz, Krzysztof
Grzelak, Ireneusz
Pawlak, Jacek
Alsharabi, Abdulsalam
Wróblewski, Tadeusz
Paluszkiewicz, Rafał
Najnigier, Bogusław
Dudek, Krzysztof
Remiszewski, Piotr
Smoter, Piotr
Grodzicki, Mariusz
Korba, Michał
Kotulski, Marcin
Cieślak, Bartosz
Kalinowski, Piotr
Gierej, Piotr
Frączek, Mariusz
Rdzanek, Łukasz
Stankiewicz, Rafał
Kobryń, Konrad
Nazarewski, Łukasz
Leonowicz, Dorota
Urban-Lechowicz, Magdalena
Skwarek, Anna
Giercuszkiewicz, Dorota
Paczkowska, Agata
Piwowarska, Jolanta
Gelo, Remigiusz
Andruszkiewicz, Paweł
Brudkowska, Anna
Andrzejewska, Renata
Niewiński, Grzegorz
Kilińska, Beata
Zarzycka, Aleksandra
Nowak, Robert
Kosiński, Cezary
Korta, Teresa
Ołdakowska-Jedynak, Urszula
Sańko-Resmer, Joanna
Foroncewicz, Bartosz
Ziółkowski, Jacek
Mucha, Krzysztof
Senatorski, Grzegorz
Pączek, Leszek
Habior, Andrzej
Lechowicz, Robert
Polański, Sławomir
Leowska, Elżbieta
Pacho, Ryszard
Andrzejewska, Małgorzata
Rowiński, Olgierd
Kozieł, Sławomir
Żurakowski, Jerzy
Ziarkiewicz-Wróblewska, Bogna
Górnicka, Barbara
Hevelke, Piotr
Michałowicz, Bogdan
Karwowski, Andrzej
Szczerbań, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/1396689.pdf
Data publikacji:
2012-06-01
Wydawca:
Index Copernicus International
Tematy:
liver transplantation
indications
results
mortality
Opis:
The aim of the study was to analyze indications and results of the first one thousand liver transplantations at Chair and Clinic of General, Transplantation and Liver Surgery, Medical University of Warsaw.Material and methods. Data from 1000 transplantations (944 patients) performed at Chair and Clinic of General, Transplantation and Liver Surgery between 1994 and 2011 were analyzed retrospectively. These included 943 first transplantations and 55 retransplantations and 2 re-retransplantations. Frequency of particular indications for first transplantation and retransplantations was established. Perioperative mortality was defined as death within 30 days after the transplantation. Kaplan-Meier survival analysis was used to estimate 5-year patient and graft survival.Results. The most common indications for first transplantation included: liver failure caused by hepatitis C infection (27.8%) and hepatitis B infection (18%) and alcoholic liver disease (17.7%). Early (< 6 months) and late (> 6 months) retransplantations were dominated by hepatic artery thrombosis (54.3%) and recurrence of the underlying disease (45%). Perioperative mortality rate was 8.9% for first transplantations and 34.5% for retransplantations. Five-year patient and graft survival rate was 74.3% and 71%, respectively, after first transplantations and 54.7% and 52.9%, respectively, after retransplantations.Conclusions. Development of liver transplantation program provided more than 1000 transplantations and excellent long-term results. Liver failure caused by hepatitis C and B infections remains the most common cause of liver transplantation and structure of other indications is consistent with European data.
Źródło:
Polish Journal of Surgery; 2012, 84, 6; 304-312
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Microscopic analysis of the nanostructures impact on endothelial cells
Autorzy:
Kołodziejczyk, Agnieszka Maria
Kucińska, Magdalena
Jakubowska, Aleksandra
Siatkowska, Małgorzata
Sokołowska, Paulina
Kotarba, Sylwia
Makowski, Krzysztof
Komorowski, Piotr
Walkowiak, Bogdan
Powiązania:
https://bibliotekanauki.pl/articles/1844983.pdf
Data publikacji:
2020
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
nanostructures
atomic force microscopy
transmission electron microscopy
scanning electron microscopy
cell morphology
Opis:
Nowadays nanostructures are more and more often designed as carriers for drug delivery, especially to improve the drug pharmacokinetics and pharmaco-dynamics. Numerous kinds of nanostructures are considered a good prospect for medical applications thanks to their small size, acceptable biocompatibility and toxicity. Due to the fact that nanotechnology is a new field of science, every nano-scale product must be thoroughly examined regarding its toxicity to the human body. This study provides new insights into effects of exposing endothelial cells to the selected nanostructures. Dendrimers of the fourth generation (PAMAMs), multi-walled carbon nanotubes (MWCNTs) and silver nanoparticles (SNPs) were used to evaluate nanostructures influence on endothelial cells in vitro. The nanostructures were evaluated via transmission electron microscopy and dynamic light scattering technique. The cells previously exposed to the nanostructures were observed and analyzed via the atomic force microscopy and scanning electron microscopy to obtain a quantitative evaluation of the cells morphology. The presence of multi-walled carbon nanotubes and silver nanoparticles on the cells surface was confirmed by the scanning electron microscopy. Our results confirm that the surface association and/or uptake of nanostructures by the cells resulting from physicochemical and biological processes, affect the cells morphology. Morphological changes can be induced by the membrane proteins interaction with nanomaterials, which trigger a sequence of intracel-lular biological processes.
Źródło:
Engineering of Biomaterials; 2020, 23, 154; 2-8
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Microscopic analysis of the nanostructures impact on endothelial cells
Autorzy:
Kołodziejczyk, Agnieszka Maria
Kucińska, Magdalena
Jakubowska, Aleksandra
Siatkowska, Małgorzata
Sokołowska, Paulina
Kotarba, Sylwia
Makowski, Krzysztof
Komorowski, Piotr
Walkowiak, Bogdan
Powiązania:
https://bibliotekanauki.pl/articles/970974.pdf
Data publikacji:
2020
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
nanostructures
atomic force microscopy
transmission electron microscopy
scanning electron microscopy
cell morphology
Opis:
Nowadays nanostructures are more and more often designed as carriers for drug delivery, especially to improve the drug pharmacokinetics and pharmaco-dynamics. Numerous kinds of nanostructures are considered a good prospect for medical applications thanks to their small size, acceptable biocompatibility and toxicity. Due to the fact that nanotechnology is a new field of science, every nano-scale product must be thoroughly examined regarding its toxicity to the human body. This study provides new insights into effects of exposing endothelial cells to the selected nanostructures. Dendrimers of the fourth generation (PAMAMs), multi-walled carbon nanotubes (MWCNTs) and silver nanoparticles (SNPs) were used to evaluate nanostructures influence on endothelial cells in vitro. The nanostructures were evaluated via transmission electron microscopy and dynamic light scattering technique. The cells previously exposed to the nanostructures were observed and analyzed via the atomic force microscopy and scanning electron microscopy to obtain a quantitative evaluation of the cells morphology. The presence of multi-walled carbon nanotubes and silver nanoparticles on the cells surface was confirmed by the scanning electron microscopy. Our results confirm that the surface association and/or uptake of nanostructures by the cells resulting from physicochemical and biological processes, affect the cells morphology. Morphological changes can be induced by the membrane proteins interaction with nanomaterials, which trigger a sequence of intracel-lular biological processes.
Źródło:
Engineering of Biomaterials; 2020, 23, 154; 2-8
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł

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