Autor: Bigda, Jacek - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Molecular cloning and sequencing of partial cDNA of tumor necrosis factor and p75 tumor necrosis factor receptor of Syrian golden hamster (Mesocricetus auratus) with the use of universal primers.
Autorzy:: Dobrzańska, Zuzanna
Więckiewicz, Joanna
Bigda, Jacek
Powiązania:: https://bibliotekanauki.pl/articles/1043771.pdf
Data publikacji:: 2002
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: PCR primers
p75 TNF-R
TNF
hamster
Opis:: In this study we cloned and analysed partial cDNA of tumor necrosis factor (TNF) and p75 TNF-R receptor of Syrian golden hamster (Mesocricetus auratus). We obtained a 382-bp sequence of TNF and a 148-bp sequence coding for p75 TNF-R. The primers used for the cloning were designed on the basis of inter-species homology, thus presumably can be used for cloning and analysis of TNF and p75 TNF-R genes of other mammals.
Źródło:: Acta Biochimica Polonica; 2002, 49, 2; 427-431
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Antitumor activity of antimicrobial peptides against U937 histiocytic cell line
Autorzy:: Koszałka, Patrycja
Kamysz, Elżbieta
Wejda, Magdalena
Kamysz, Wojciech
Bigda, Jacek
Powiązania:: https://bibliotekanauki.pl/articles/1039961.pdf
Data publikacji:: 2011
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: U937 cells
lipopeptide
antimicrobial peptides
Opis:: We investigated cytotoxic activity of antimicrobial peptides of different origin (both naturally occurring and synthetic), structure and known mechanisms of action against human histiocytic lymphoma cell line U937. The strongest cytotoxic activity against U937 cell line was shown by Pexiganan MSI-78, followed by Citropin 1.1, Protegrin 1 and a synthetic lipopeptide, N-α-palmitoyl-l-lysyl-l-lysine amide (Pal-Lys-Lys-NH2). The cytotoxic activity of the peptides was more dependent on the time of incubation than concentration. Only for the lipopeptide, whose mode of action was restricted to disruption of electric potential of the cell membrane, the correlation between cytotoxicity and concentration was almost linear. The high cytotoxicity of Pexiganan MSI-78, Protegrin 1 and the lipopeptide could be basically explained by their membranolytic activity leading to necrosis. However, in the case of Citropin 1.1, the cell membrane integrity was disrupted only slightly and independently of the peptide concentration. Therefore, some other mechanism of action might be responsible for its strong dose-dependent cytotoxic activity, e.g., membranolytic activity leading to apoptosis. Furthermore, TNF-α production due to LPS (lipopolysaccharide) stimulation was suppressed by the presence of Citropin 1.1, Pexiganan MSI-78 or Protegrin 1, but not by Buforin 2 or the lipopeptide. Our experiments have shown that cytotoxic activity is not limited to some specific molecular structure of a peptide, but rather to the length of the peptide chain as it is likely to affect the efficiency of the tumor cell membrane disruption and interaction with LPS.
Źródło:: Acta Biochimica Polonica; 2011, 58, 1; 111-117
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Periodic Inspections of Residential Heating Appliances for Solid Fuels: Review of Legal Regulations in Selected European Countries
Autorzy:: Rychlewska, Katarzyna
Telenga-Kopyczyńska, Jolanta
Bigda, Rafał
Żeliński, Jacek
Powiązania:: https://bibliotekanauki.pl/articles/1838248.pdf
Data publikacji:: 2021
Wydawca:: Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:: emission
residential sector
solid fuel boiler
solid fuel
space heater
legal regulation
Opis:: The article presents the legal framework of periodic control systems of individual heating devices in the Federal Republic of Germany, the Czech Republic and Switzerland. The scope of periodic inspections carried out in considered countries, the persons responsible for performing them, the method of data acquisition and administrative bodies responsible for supervising the fulfillment of the obligation, as well as the sanctions for law violations related to small heat sources operation in the residential sector were discussed.
Źródło:: Journal of Ecological Engineering; 2021, 22, 2; 54-62
2299-8993
Pojawia się w:: Journal of Ecological Engineering
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Periodic Inspections of Residential Heating Appliances for Solid Fuels: Review of Legal Regulations in Selected European Countries
Autorzy:: Rychlewska, Katarzyna
Telenga-Kopyczyńska, Jolanta
Bigda, Rafał
Żeliński, Jacek
Powiązania:: https://bibliotekanauki.pl/articles/1839076.pdf
Data publikacji:: 2021
Wydawca:: Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:: emission
residential sector
solid fuel boilers
solid fuel
space heater
legal regulations
Opis:: The article presents the legal framework of periodic control systems of individual heating devices in the Federal Republic of Germany, the Czech Republic and Switzerland. The scope of periodic inspections carried out in considered countries, the persons responsible for performing them, the method of data acquisition and administrative bodies responsible for supervising the fulfillment of the obligation, as well as the sanctions for law violations related to small heat sources operation in the residential sector were discussed.
Źródło:: Journal of Ecological Engineering; 2021, 22, 2; 54-62
2299-8993
Pojawia się w:: Journal of Ecological Engineering
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Using a UAV to Assess Air Pollution and Identify Dominant Emission Sources
Autorzy:: Żeliński, Jacek
Bigda, Rafał
Kucbel, Marek
Raclavská, Helena
Šafář, Michal
Švédová, Barbora
Raclavský, Konstantin
Juchelková, Dagmara
Růžičková, Jana
Telenga-Kopyczyńska, Jolanta
Powiązania:: https://bibliotekanauki.pl/articles/2202296.pdf
Data publikacji:: 2022
Wydawca:: Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:: air pollution
UAV
drone
emission measurement
pm10
residential emission
Opis:: Central Europe is the region with the highest concentration of particulate matter with aerodynamic diameter less than 10 micrometers (PM10) in outdoor air. Weather conditions combined with a high industrialization of regions laying along the Czech Republic and Poland border influence the formation of long smog episodes with PM10 concentrations in the atmosphere at the value of several hundred micrograms in a cubic meter. However, it has been observed that the main source of particulates pollution in the area of the Polish-Czech border between the most populated areas of Ostrava and Katowice is the residential heating fired with solid fuels, participating at the level of not less than 21% in overall air contamination with dusts. It particularly concerns PM10, which is one of the major harmful air pollutants produced by the combustion of solid fuels such as biomass and coal. The measures leading to decrease the dust emission from coal burned individual heat sources include methods to eliminate old-type boilers not permitted by the law, as well as illegal incineration of fuels of bad quality or including admixture of wastes. It requires a new approach for effective identification of such sources, as well as for recognition of pollutants leaving household emitters and evaluation of their share in overall effect on human health. Unmanned aerial vehicles (UAVs) equipped with miniaturized sensors detecting gaseous and dust particles at the outlet of an individual emitter can compensate the lack of information unable to be obtain using traditional measurements. The use of UAVs to identify specific sources of air pollution is still at an early stage of development and there are not too many scientific publications on this topic so far. Despite it, this technology seems to be usable to create undemanding, low-cost and effective method of air pollution sources assessment. In the current article, some aspects of using UAVs for identification of especially troublesome emission sources located on residential areas are presented, including finding the dominant emission source, determining the optimal distance between a UAV and the emission source or the influence of the UAV altitude, movement and sampling time on measurement result.
Źródło:: Journal of Ecological Engineering; 2022, 23, 12; 134--144
2299-8993
Pojawia się w:: Journal of Ecological Engineering
Dostawca treści:: Biblioteka Nauki

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