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    Wyświetlanie 1-5 z 5
    Tytuł:
    The peripheral quantitative computed tomographic and densitometric analysis of skeletal tissue in male Wistar rats after chromium sulfate treatment
    Autorzy:
    Bieńko, Marek
    Radzki, Radosław Piotr
    Wolski, Dariusz
    Powiązania:
    https://bibliotekanauki.pl/articles/991127.pdf
    Data publikacji:
    2017
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    rat
    chromium sulfate
    bone
    densitometry
    peripheral quantitative computed tomography
    bone mineral density and content
    Opis:
    Introduction. This study evaluates the effects of three different doses of chromium sulphate on bone density and the tomographic parameters of skeletal tissue of rats. Materials and method. The experiment was performed on 40 male Wistar rats which received, by gavage, during 90 days, a chromium sulphate in either a daily dose of 400, 600 or 800 μg/kg BW. At the end of experiment, the rats were scanned using the densitometry method (DXA) to determine the bone mineral density, bone mineral content of total skeleton and vertebral column (L2-L4) and parameters of body composition (Lean Mass and Fat Mass). The isolated femora were scanned using peripheral a quantitative computed tomography method (pQCT) for a separate analysis of the trabecular and cortical bone tissue. The ultimate strength, work to ultimate and the Young modulus of femora was also investigated by the threepoint bending test. Results. The negative impact of chromium was observed in relation to bone tissue. All doses significantly decreased total skeleton density and mineral content, and also had impact upon the isolated femora and vertebral column. Trabecular volumetric bone mineral density and trabecular bone mineral content measured by pQCT in distal femur metaphysis were significantly lower in the experimental groups than in the control. Higher doses of chromium also significantly decreased values of ultimate strength and Young modulus in the investigated femora. Conclusions. The results of the experiment demonstrate that chromium sulphate is dose dependent, and exerts a disadvantageous effect on the skeleton, as it decreases bone density and resistance.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2017, 24, 3
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effects of obesity on health condition with an emphasis on bone tissues disorders
    Autorzy:
    Wolski, Dariusz
    Michalik, Joanna
    Bieńko, Marek
    Radzki, Radosław P.
    Powiązania:
    https://bibliotekanauki.pl/articles/454811.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    fat tissue
    bone
    obesity
    osteosarcopenic obesity osteoporosis
    Opis:
    Introduction. Obesity is today one of the most dangerous and the fastest growing civilization diseases in the world. The number of overweight or obese people is continually increasing. Obesity is defined as abnormal fat accumulation in an organism that may cause health impairment. Obesity may be conducive to an increased risk increase for occurrence of cardiovascular diseases as well as stroke, some types of cancer, endocrinal disorders, osteoarthritis and other bone disorders. Some studies have demonstrated that high body mass index (BMI) is protective against the development of osteoporosis and osteoporotic fractures in men and women. In slim people with a lower BMI than normal, weight loss is associated with low bone mineral density (BMD). On the other hand, obesity in childhood may lead to fragility fractures and may lead to early development of osteoporosis in adulthood. Currently, we have numerous methods for measurement of obesity such as dual-energy X-ray absorptiometry (DXA), bioelectrical impedance analysis (BIA), total body electrical conductivity (TOBEC) as well as magnetic resonance imaging (MRI) and computed tomography (CT). These methods are useful for diagnosing obesity and bone tissue disorders such as osteopenia with sarcopenia or osteoporosis, in particular in perimenopausal women and men after andropause. Aim of the study. The purpose of the study was review the literature on obesity and bone tissue disorders and their interrelations. Material and method. Analysis of literature.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2018, 2; 117-122
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Life quality of patients with the carpal tunnel syndrome
    Autorzy:
    Wolska, Joanna Michalik
    Wolski, Dariusz
    Bieńko, Marek
    Radzki, Radosław P.
    Powiązania:
    https://bibliotekanauki.pl/articles/454906.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    carpal tunel syndrome
    quality of life
    neuropathiers
    Opis:
    Introduction. Carpal tunnel syndrome (CTS) is a neuropathy caused by pressure on the median nerve taking a course in the carpal tunnel. The characteristic symptoms of CTS are: pain, numbness, and a prickling sensation in the hand usually at night or after the physical effort. Symptoms of the disease affect patient quality of life which is desribed as a subjective estimation of life situation. Aim. The aim of this study was to assess the quality of patient life in those who suffer from carpal tunel syndrome. The studies were aimed to descripe the general quality of patient life and the effect of symptoms on individual aspects in the life of the afflicted. Materials and methods. The study sample was composed of 60 patients from rehabilitation and physiotherapy institutions located in the Lublin Voivodship (Poland). The studies were based on the questionnaries of life quality estimation dependent on health WHOQOL- BREF and EQ-5D-5L as well as on our own poll questionnaire. Conclusions. Symptoms of carpal tunel syndrome deteriorate the quality of patient life. Such patients have difficulties with daily activities. Among those examined, as many as 94.12% reported problems performing everyday actions (EQ – 5D – 5L). Difficulties with chores were reported by 86.70% of those examined. The patients with carpal tunel syndrome are less effective at work. Reduced achievements at work were reported by 73.30% of those examined, and a need for a shorter work day was reported by 60%. For 53.30%, difficulties in doing their jobs were significant; 20% of the examined had to change their profession or work station. The examined patients often experienced pain which deteriorated quality of sleep and disturbed everyday functioning. The patients were presented with serious difficulties in doing professional work.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2018, 3; 217-223
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evaluation of the knowledge of the issues related to human papillomavirus infections within young women
    Autorzy:
    Węgorowski, Paweł
    Michalik, Joanna
    Turkowska, Karolina
    Stanisławek, Andrzej
    Wolski, Dariusz
    Bieńko, Marek
    Radzki, Radosław P.
    Powiązania:
    https://bibliotekanauki.pl/articles/454862.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    HPV virus
    human papillomavirus cervical cancer
    Opis:
    Introduction. Human papillomavirus infections are frequent in on average 9% to 13% of the female population, and the risk of infection throughout life exceeds 50%. The HPV virus causes changes in the mucous membranes and the skin of the genital area in both women and men. Aim. This paper presents epidemiology, prophylaxis, diagnostics and treatment of HPV and cervical cancer infections. In addition, the knowledge of issues related to human papillomavirus infection among young women was assessed. Materials and methods. The diagnostic survey method was used to carry out the research. The research tool was a questionnaire of own authorship consisting of 41 questions. The research group consisted of 240 women. The research was carried out from June to September 2016 at the Chodźki Medical Center and the Luxmed facility in Lublin. Results. There is a relationship between the education of the respondents and their knowledge about the human papillomavirus infection. The studies did not show a significant relationship between the self-esteem of the studied women and whether they were vaccinated against the HPV virus (Chi-square = 0.362, p = 0.547). Conclusions. The general level of knowledge on issues related to human papillomavirus infection among young women is at the secondary level. A higher level of general knowledge was shown by women with better education, related to the medical and biological sciences. The self-assessment of the respondents coincides with the general knowledge, based on detailed questions, on issues related to HPV infection. Promoting knowledge about HPV infection is unsatisfactory
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2018, 4; 308-316
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ochratoxin A and Aflatoxin B1 as Factors of Bone Damage and Neurodegeneration Through the Influence on the Immunomodulation Processes of TNF-α and IL-6 Concentrations
    Autorzy:
    Radzka-Pogoda, Agnieszka
    Radzki, Radosław Piotr
    Bieńko, Marek
    Szponar, Jarosław
    Sokołowska, Barbara
    Kulik, Anna
    Lewicka, Małgorzata
    Borzęcki, Andrzej
    Powiązania:
    https://bibliotekanauki.pl/articles/32874334.pdf
    Data publikacji:
    2022
    Wydawca:
    Polskie Towarzystwo Medycyny i Techniki Hiperbarycznej
    Tematy:
    bone metabolism
    bone development
    bone remodelling
    mycotoxin
    aflatoxin B1
    ochratoxin A
    neurodegeneration
    Opis:
    The wide distribution of mycotoxins, including aflatoxin B1 and ochratoxin A, in the environment and their influence on living organisms make them an interesting research problem. Numerous complications of intoxication with these substances are known, however, particular attention is paid to the effects on the skeletal and nervous systems. The inflammatory effect, presented by the increase in the concentration of cytokines - IL-6 and TNF-α may influence the immune dysregulation present in bone metabolism disorders, as well as in neurodegeneration. Mycotoxins also contribute to osteodegeneration by modifying vitamin D metabolism. Interestingly, and still unexplored, is the mechanism of intrauterine influence on bone metabolism and neurodegeneration processes. Understanding the above mechanisms may help in monitoring the toxic effects of intoxication with these toxins. It can also help develop methods of therapy for poisoning with this compound, in animals and humans.
    Źródło:
    Polish Hyperbaric Research; 2022, 3(80); 61-72
    1734-7009
    2084-0535
    Pojawia się w:
    Polish Hyperbaric Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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