- Tytuł:
- Cellular aspects of folate and antifolate membrane transport.
- Autorzy:
-
Brzezińska, Agnieszka
Wińska, Patrycja
Balińska, Małgorzata - Powiązania:
- https://bibliotekanauki.pl/articles/1044317.pdf
- Data publikacji:
- 2000
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
antifolates
folate receptor
chemotherapy
folate carrier
folates - Opis:
- Folates - one carbon carriers - take part in the metabolism of purine, thymidylate and some amino acids. Internalization of these compounds employs several mechanisms of transport systems. Reduced folate carriers and folate receptors play the most important role in this process. The physiological role of these molecules in normal and neoplastic cells is described regarding changes in transport activity and connection of transport systems with resistance to antifolates and cancer development.
- Źródło:
-
Acta Biochimica Polonica; 2000, 47, 3; 735-749
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł