Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Yкраїнський (UK)
Przejdź do strony domowej biblioteki Centralna Biblioteka Wojskowa Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaCentralna Biblioteka Wojskowa

Wyszukujesz frazę "BRZEZIŃSKA, ANNA" wg kryterium: Autor

  Lista filtrów
Wyrównaj
Wyświetlanie 1-15 z 63
Tytuł:
A study of the influence of newly synthesized acyclonucleosides and 1,2,3,4-tetrahydroisoquinoline derivatives on deoxythymidine and deoxycytidine kinase activities in human neurofibrosarcoma and ovarian cancer.
Autorzy:
Modrzejewska, Hanna
Brzezińska, Elżbieta
Dramiński, Marcin
Zgit-Wróblewska, Anna
Krzykowska, Katarzyna
Rozpończyk, Elżbieta
Greger, Janusz
Powiązania:
https://bibliotekanauki.pl/articles/1043410.pdf
Data publikacji:
2003
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
deoxynucleoside kinases
1,2,3,4-tetrahydroisoquinoline
acyclonucleosides
Opis:
The influence of nine newly synthesized uracil acyclonucleosides, and 36 derivatives of 1,2,3,4-tetrahydroisoquinoline on the activity of enzymes catalysing dTMP and dGMP synthesis, on the content of dTTP and dGTP in acid soluble fraction and on the incorporation of [14C]dThd and [14C ]dGuo into DNA in tumour homogenates was studied. The influence of the compounds was studied in the cytosol from intraoperatively excised human tumours - neurofibrosarcoma and ovarian cancer. It was shown that dTMP and dGMP synthesis is inhibited competitively by 34.1±4.0% in both types of tumours by 0.2 mM 1-N-(3'-hydroxypropyl)-6-methyluracil (1) and 0.2 mM 1-N-(3'-hydroxypropyl)- 5,6- tetramethyleneuracil (2). The mentioned acyclonucleosides reduced the content of dTTP and dGTP in the acid soluble fraction of tumours (59.7±3.1% of control). 1-(4-chlorophenyl)-6,7-dihydroxy- 1,2,3,4-tetrahydroisoquinoline (3), 1-(2,3-dichlorophenyl)-6,7-dihydroxy 1,2,3,4-tetrahydroisoquinoline (4) and 1-(3-methoxyphenyl)-6,7-dihydroxy 1,2,3,4-tetrahydroisoquinoline (5) at 0.2 mM concentration caused a mixed type inhibition of the synthesis of dTMP and dGMP by, on average, 33.2±4.4%, and reduced the content of dTTP and dGTP in the acid soluble fraction (52.6±3.7% of control) but were active only in the cytosol of neurofibrosarcoma. While acyclonucleosides undergo phosphorylation in the cytosol by cellular kinases, with their triphosphates being active acyclonucleoside metabolites, active 1,3,4,5-tetrahydroisoquinoline derivatives (compounds not containing a deoxyribose moiety), cannot be phosphorylated. ACN and THI derivatives which inhibit dThd and dCyd kinase activities, inhibit also the incorporation of [14C]dThd and [14C]dGuo (ACN - 50.2±2.7%, THI - 53.4±3.9% of incorporation inhibition) into tumour DNA. The obtained results point to the mechanism of uracil acyclonucleosides and 1,2,3,4-tetrahydroisoquinoline biological activity consisting in inhibiting the synthesis of DNA components.
Źródło:
Acta Biochimica Polonica; 2003, 50, 4; 1175-1185
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Anna Danuta Szyfer
Autorzy:
Brzezińska, Anna Weronika
Powiązania:
https://bibliotekanauki.pl/articles/597410.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Ludoznawcze
Opis:
Wspomnienie z zmarłej prof. Annie Danucie Szyfer
Źródło:
Lud; 2018, 102
0076-1435
Pojawia się w:
Lud
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Atmosphere of societal anxiety and representations of the body: The image of man in surrealist works of Vítězslav Nezval in the 20th century interwar period in Bohemia
Autorzy:
Brzezińska, Anna Maria
Powiązania:
https://bibliotekanauki.pl/articles/628341.pdf
Data publikacji:
2018
Wydawca:
Fundacja Pro Scientia Publica
Tematy:
czech surrealism, Vítězslav Nezval, social anxiety, Absolute Gravedigger, Woman in Plural, metamorphosis,
Opis:
Aim: The interwar period in Czechoslovakia was a time of societal anxiety. The aim of this paper is to find the central themes of societal fear, as reflected in the surrealist works of Vítězslav Nezval, a czech poet. The analysis will be based primarily on the lyric poetry from the collections: Žena v množném čísle [Woman in Plural] (1936) and Absolutní hrobař [Absolute Gravedigger] (1937). Methods: The analysis is based on the Josef Vojdovík’s anthropo-phenomenological method of exploring the surrealist perceptions of the body, which is based on vertical and horizontal anthropological dimensions and phenomenological conceptions of fears. Results: Surrealist poetry and other literary works contain images of the body that are changed by fear: deformations, metamorphoses, fragmentarisations, hybridisations, expressing the body as a collage, a mosaic, an amalgam, a phantom, a grotesque, an inlay, and as lifelessness. It undergoes multiple metamorphoses, not only within its own form, but also with regard to the categories of life and lifelessness. Conclusions: The analysis leads to the conclusion, that V. Nezval’s works show a clear tendency to portray the body as an object which undergoes a metamorphosis. The body is balanced on the edge between living and dead, organic and inorganic, it is determined by time and space. It is often shown along the narrowing-widening relation, in stupor, petrification, reduced to a flat surface or miniaturised.
Źródło:
Journal of Education Culture and Society; 2018, 9, 1; 181-189
2081-1640
Pojawia się w:
Journal of Education Culture and Society
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bamber przez duże „B”. Recenzja wystawy Ty Bambrze prezentowanej w Muzeum Etnograficznym, Oddziale Muzeum Narodowego w Poznaniu
Autorzy:
Brzezińska, Anna Weronika
Powiązania:
https://bibliotekanauki.pl/articles/1201055.pdf
Data publikacji:
2020
Wydawca:
Polskie Towarzystwo Ludoznawcze
Źródło:
Zbiór Wiadomości do Antropologii Muzealnej; 2020, 7; 369-377
2391-6869
Pojawia się w:
Zbiór Wiadomości do Antropologii Muzealnej
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Curcumin induces cell death without oligonucleosomal DNA fragmentation in quiescent and proliferating human CD8+ cells
Autorzy:
Magalska, Adriana
Brzezinska, Agnieszka
Bielak-Zmijewska, Anna
Piwocka, Katarzyna
Mosieniak, Grażyna
Sikora, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1041209.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
CD8+
cell death
DNA degradation
curcumin
Opis:
Cytotoxic CD8+ cells play an important role in determining host response to tumor, thus chemotherapy is potentially dangerous as it may lead to T cells depletion. The purpose of this study was to elucidate the propensity of quiescent and proliferating human CD8+ cells to undergo cell death upon treatment with curcumin, a natural dye in Phase I of clinical trials as a prospective chemopreventive agent. Methods: We treated human quiescent or proliferating CD8+ cells with 50 µM curcumin or irradiated them with UVC. Cell death symptoms such as decreased cell viability, chromatin condensation, activation of caspase-3 and specific DFF40/CAD endonuclease and oligonucleosomal DNA fragmentation were analyzed using MTT test, microscopic observation, Western blotting and flow cytometry. Results: Curcumin decreased cell viability, activated caspase-3 and decreased the level of DFF45/ICAD, the inhibitor of the DFF40/CAD endonuclease. However, this did not lead to oligonucleosomal DNA degradation. In contrast, UVC-irradiated proliferating, but not quiescent CD8+ cells revealed molecular and morphological changes characteristic for apoptosis, including oligonucleosomal DNA fragmentation. Curcumin can induce cell death in normal human lymphocytes both quiescent and proliferating, without oligonucleosomal DNA degradation which is considered as a main hallmark of apoptotic cell death. Taking into account the role of CD8+ cells in tumor response, their depletion during chemotherapy could be particularly undesirable.
Źródło:
Acta Biochimica Polonica; 2006, 53, 3; 531-538
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
DZIAŁALNOŚĆ MUZEUM OKRĘGOWEGO ZIEMI KALISKIEJ W ZAKRESIE PROMOCJI WZORNICTWA WIELKOPOLSKIEGO
Autorzy:
Brzezińska, Anna Weronika
Powiązania:
https://bibliotekanauki.pl/articles/597415.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Ludoznawcze
Tematy:
muzeum
wystawa
warsztaty
Cepelia
ziemia kaliska
Opis:
Komunikat o najnowszych dziłaniach Muzeum Okręgowego Ziemi Kaliskiej.
Źródło:
Lud; 2018, 102
0076-1435
Pojawia się w:
Lud
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Dziecko w systemie edukacji: podejście systemowo-transakcyjne
Autorzy:
Brzezińska, Anna Izabela
Czub, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/2045781.pdf
Data publikacji:
2015-03-31
Wydawca:
Wydawnictwo Adam Marszałek
Tematy:
discourse of quality
discourse of meaning making
child’s readiness
educational system’s readiness
dynamic systems
Opis:
Article addresses the problem of child’s and the educational system’s readiness to start school by children six years old. It is a proposition of different approach to this problem and recognizing school readiness in a double perspective, as ‘the readiness (of the child) to school’ and ‘readiness of the school (for a child)’. It gives an opportunity to take into account a broad range of factors involved in the process leading to effective support of the child in the education system and support of the education system. The text is also a proposal to change the way of leading public debate on education and reducing of school age. It introduces the concept of ‘discourse of quality’ and ‘iscourse of meaning making’ as an alternative which allows consideration of different points of view and striving for mutual understanding. It also introduces a proposal to adopt a theoretical framework for analyzing the readiness of state, society, institutions, families, and the childe for mutual interactions. The aim of these interactions is to increase the effectiveness in realizing both, personal and social goals. The purpose of this article is an attempt to leave the vicious circle of ‘discourse of quality’, which in current, Polish reality, underlies growing social divisions and conflicts between ‘followers’ of different approaches to childhood, upbringing and education. It is a proposal to adopt such perspective to analysis of the problem, which can be a basis for planning practical solutions in the sphere of public debate and planning activities within the ‘child - institution’ system.
Źródło:
Kultura i Edukacja; 2015, 1(107); 11-33
1230-266X
Pojawia się w:
Kultura i Edukacja
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Editorial. Becoming an adult - contexts of identity development
Autorzy:
Brzezińska, Anna Izabela
Powiązania:
https://bibliotekanauki.pl/articles/430420.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
dimensions of identity
early adulthood
early and late adolescence
educational level
emerging adulthood
emotional regulation
guilt proneness
identity status
identity style
shame proneness
social participation
Źródło:
Polish Psychological Bulletin; 2013, 44, 3; 239-244
0079-2993
Pojawia się w:
Polish Psychological Bulletin
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Estetyka dzieła literackiego w strukturalistycznej koncepcji Jana MukaŘovskiego
Aesthetics of a literary work in the structuralist conception of Jan Mukařovský
Autorzy:
Brzezińska, Anna
Powiązania:
https://bibliotekanauki.pl/articles/460046.pdf
Data publikacji:
2014
Wydawca:
Fundacja Pro Scientia Publica
Tematy:
strukturalizm praski
Praskie Koło Lingwistyczne
Jan Mukařovski
narratologia
structuralism in Prague
Prague linguistics circle
Jan Mukařovský
narratology
Opis:
Strukturalizm jako kierunek badań literaturoznawczych i lingwistycznych był w latach dwudziestych i trzydziestych XX w. wiodący na uniwersytetach I Republiki Czechosłowackiej. Artykuł skupia się na jednym z najważniejszych członków Praskiego Koła Lingwistycznego, strukturaliście Janie Mukařovskim i jego studiach na temat estetyki w duchu strukturalizmu. Przedefi niował on pojęcia estetycznej wartości, normy i funkcji, a także stworzył wiele innych elementów spójnej teorii naukowej. Przepracował zagadnienia struktury, semantycznego gestu i indywidualności w sztuce. Elementy jego teorii zostały użyte przez neostrukturalistów i dzisiejszych narratologów do analizy dzieł literackich.
Structuralism as an area in literary science researches was a main topic at the universities of the First Czechoslovak Republic in the Þ rst half of twentieth century. The article focuses on one of the most important members of the Prague linguistics circle, structuralist Jan Mukařovský and his studies about esthetics in spirit of structuralism. He has redeÞ ned the concept of esthetic value, norm and function and also made many others elements of coherent science theory. He has worked on the concepts of structure, semantic gesture and individuality in art. Elements of his theory were used by neo- structuralists and nowadays narratologists in the analyses of literary works.
Źródło:
Ogrody Nauk i Sztuk; 2014, 4; 656-663
2084-1426
Pojawia się w:
Ogrody Nauk i Sztuk
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Fabrication of filter membrane of organic compound to protect the upper respiratory tract from viral and bacterial infections, including SARS-CoV-2, compliant with FFP2 standard
Autorzy:
Brzezińska, Natalia
Pyza, Maciej
Kłeczek, Anna
Kulińska, Karolina
Gabor, Jadwiga
Garczyk-Mundała, Żaneta
Świnarew, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/24200848.pdf
Data publikacji:
2022
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
face masks
viral and bacterial infections
betulin
filtering membrane
FFP2 standard
Opis:
Bacteria, viruses, and other pathogens in the surrounding environment are biological threat to human health and life. The development of various diseases in the world, as well as the pandemic caused by the rapid spread of the SARS-CoV-2 virus, have increased the demand for the use of upper respiratory protection devices. Out of concern for the natural environment, the aim of this work was to develop an innovative solution i.e. the FFP3 filtering membrane made of an organic compound. First, preliminary tests of the FFP2 mask were carried out to assess the chemical composition, morphological structure - fibers geometry, thickness, density, and arrangement. The FTIR analysis study was conducted to confirm that the main chemical in the mask was polypropylene (PP) and high-density polyethylene (HDPE). Optical, confocal microscopy and computer microtomography studies showed the fibers structure. They were densely arranged and their thickness was less than 1 den. The fiber structure of the FFP2 mask was also compared before and after immersing in betulin, an organic compound obtained from birch bark via the Soxhlet extraction. In addition, the assessment of microbiological activity was made on the reference strain Escherichia coli ATCC 25922, and the anti-inflammatory activity on normal human skin fibroblasts on polycarbonate with betulin. The studies showed that betulin supported the material antibacterial and anti-inflammatory properties.
Źródło:
Engineering of Biomaterials; 2022, 25, 166; 2--11
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Factors influencing disabled people’s professional activity: personal and social capital
Autorzy:
Brzezińska, Anna Izabela
Kaczan, Radosław
Piotrowski, Konrad
Rycielski, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/704283.pdf
Data publikacji:
2008
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
handicapped persons
personal capital
social capital
vocational status
life satisfaction
Opis:
The following article is the second in a series (see „Nauka” 1/2008) presenting the results concerning the relationship between personal and social capital and level of life satisfaction among disabled people engaged in various professions. Personal capital is constructed on the basis of early socialization experiences within the family such as: number of responsibilities set by parents, degree of freedom, independent decision making, and parent-child relations. Social capital includes: respondent’s level of education (measured by years of studies), parent’s education, number of acquaintances, number of disabled people among acquaintances, family’s reaction to respondent’s needs and problems, and respondent’s perception of family support. Personal capital is an important predictor of life satisfaction among three subject groups – those engaged in employment activities (employed, formerly employed and searching for work, presently unemployed and not searching for work). Family support was isolated as an important predictor of life satisfaction among all five groups designated by professional status.
Źródło:
Nauka; 2008, 2
1231-8515
Pojawia się w:
Nauka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Factors influencing disabled people’s professional activity: personal characteristics
Autorzy:
Brzezińska, Anna Izabela
Kaczan, Radosław
Piotrowski, Konrad
Rycielski, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/703294.pdf
Data publikacji:
2008
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
disability
personal competencies
professional status
quality of life
Opis:
The following article is the third publication presenting the results of a study concerning the professional activity of handicapped people (see: „Nauka” 1/2008 and „Nauka” 2/2008). The purpose of this part of the research was to determine whether there is a relationship between professional status, life satisfaction, and various personal competencies among handicapped people. Apart from this, we also wanted to establish what conditions personal competencies by focusing on social-demographic factors and disability characteristics. The tested competencies were isolated from the administered questionnaire using a factor analysis. Seven factors were found: locus of control, level of aspiration, potential for development, effort invested in development, impulsiveness, stamina, and mood. Analysis of the results leads to the following conclusions: (1) personal competencies are significantly related to professional activity for handicapped people, as is level of life satisfaction, (2) personal competencies are related to external factors shaping the development of handicapped people, such as: dwelling, gender, level of disability, and type of disability.
Źródło:
Nauka; 2008, 3
1231-8515
Pojawia się w:
Nauka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Factors influencing disabled people’s professional activity: the success and risk factors
Autorzy:
Brzezińska, Anna Izabela
Kaczan, Radosław
Piotrowski, Konrad
Rycielski, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/703191.pdf
Data publikacji:
2008
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
disability
occupational activity
quality of life
risk factors
success factors
Opis:
The article is the forth one prepared by our team in the series of research on life quality and occupational activity among people with ability limitations („Nauka” 1/2008, „Nauka” 2/2008, „Nauka” 3/2008). The aim of the presented analysis was to create the complex model of determinants for occupational activities of people with disabilities that takes into account the broadest possible look-out. That is why we used the variables from all the fields analyzed in the previous papers in this series i.e. (1) SES; (2) characteristics of disabilities (the type, the degree, the age of acquiring disability); (3) upbringing characteristics in childhood; (4) social network; (5) personal capacities. In order to discover the significant determinants of occupational activities and quality of life among people with different disabilities – which could be both risk and success factors – we have divided the subjects into four groups according to two variables: (1) occupationally active or inactive patients and (2) patients satisfied/dissatisfied with their own income.The group with the largest observed number of risk factors has consisted of the subjects that have been inactive (non-looking for a job) and unsatisfied with their own income. Gender, city size, education, received support, social relations, disability characteristics, upbringing characteristics and personality traits have turned out to be significant risk/success factors. Moreover the results show that in different groups of people with disabilities we find different settings of risk and success factors.
Źródło:
Nauka; 2008, 4
1231-8515
Pojawia się w:
Nauka
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 63

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies