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    Tytuł:
    The dynamics of biochemical markers of enzymoemia and middle-weight molecules in the early post-traumatic period of brain injury
    Autorzy:
    Ziablitsev, S. V.
    Elskyy, V. N.
    Pischulina, S. V.
    Strelchenko, U. I.
    Antonov, E. V.
    Sudilovskaya, U. L.
    Khudoley, S. A.
    Powiązania:
    https://bibliotekanauki.pl/articles/1032378.pdf
    Data publikacji:
    2014
    Wydawca:
    Uniwersytet Kazimierza Wielkiego w Bydgoszczy
    Tematy:
    brain injury
    biochemical markers
    enzymoemia
    middle-weight molecules
    Opis:
    In the experimental model of brain injury (BI) markers of enzymoemia (aminotransferases ALT and AST, alkaline and acid phosphatase (AlP and AcP), cathepsin D (CD)) and middle-weight molecules (MWM) were estimated. 3 hours after trauma there were increase of all enzymes that evidences about damage of cytoplasmic (ALT, AST, AlF) and lysosomal membranes (AcP, CD). During period of observation different dynamics of enzymatic changes occurred: plateau phase for ALT and CD and progressive increase of concentration with the maximum on the 5th day of the experiment for AlP and AcP. Increase of the level of MWM displayed the development of endogenous intoxication in the post-traumatic period. Relation between particular components of MWM was studied. It was shown that primary accumulation of nucleotide fraction and aromatic peptides is adverse factor of the course of post-traumatic period, development of endotoxicosis, and multiorgan failure.
    Źródło:
    Journal of Health Sciences; 2014, 4, 1; 297-302
    1429-9623
    Pojawia się w:
    Journal of Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The experimental and theoretical investigations of damage development and distribution in double-forged tungsten under plasma irradiation-initiated extreme heat loads
    Autorzy:
    Väli, B.
    Laas, T.
    Paju, J.
    Shirokova, V.
    Paduch, M.
    Gribkov, V. A.
    Demina, E. V.
    Pimenov, V. N.
    Makhlaj, V. A.
    Antonov, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/148167.pdf
    Data publikacji:
    2016
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    divertor material
    nuclear fusion
    off-normal events
    thermal shock
    tungsten
    Opis:
    The influence of extreme heat loads, as produced by a multiple pulses of non-homogeneous flow of slow plasma (0.1–1 keV) and fast ions (100 keV), on double-forged tungsten (DFW) was investigated. For generation of deuterium plasma and fast deuterons, plasma-focus devices PF-12 and PF-1000 are used. Depending on devices and conditions, the power flux density of plasma varied in a range of 107–1010 W/cm2 with pulse duration of 50–100 ns. Power flux density of fast ions was 1010–1012 W/cm2 at the pulse duration of 10–50 ns. To achieve the combined effect of different kind of plasmas, the samples were later irradiated with hydrogen plasma (105 W/cm2, 0.25 ms) by a QSPA Kh-50 plasma generator. Surface modification was analysed by scanning electron microscopy (SEM) and microroughness measurements. For estimation of damages in the bulk of material, an electrical conductivity method was used. Investigations showed that irradiation of DFW with multiple plasma pulses generated a mesh of micro- and macrocracks due to high heat load. A comparison with single forged tungsten (W) and tungsten doped with 1% lanthanum-oxide (WL10) reveals the better crack-resistance of DFW. Also, sizes of cells formed between the cracks on the DFW’s surface were larger than in cases of W or WL10. Measurements of electrical conductivity indicated a layer of decreased conductivity, which reached up to 500 µm. It depended mainly on values of power flux density of fast ions, but not on the number of pulses. Thus, it may be concluded that bulk defects (weakening bonds between grains and crystals, dislocations, point-defects) were generated due to mechanical shock wave, which was generated by the fast ions flux. Damages and erosion of materials under different combined radiation conditions have also been discussed.
    Źródło:
    Nukleonika; 2016, 61, 2; 169-177
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-2 z 2

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