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Wyszukujesz frazę "Aladag, Mehmet" wg kryterium: Autor


Wyświetlanie 1-2 z 2
Tytuł:
Reverse engineering of parts with asymmetrical properties using replacement materials
Autorzy:
Aladag, Mehmet
Bernacka, Monika
Joka-Yildiz, Magdalena
Grodzki, Wojciech
Zamojski, Przemysław
Zgłobicka, Izabela
Powiązania:
https://bibliotekanauki.pl/articles/2204590.pdf
Data publikacji:
2022
Wydawca:
Politechnika Białostocka. Oficyna Wydawnicza Politechniki Białostockiej
Tematy:
material characterisation
reverse engineering
additive manufacturing
finite element analysis
rapid prototyping
Opis:
Reverse engineering (RE) aims at the reproduction of products following a detailed examination of their construction or composition. Nowadays, industrial applications of RE were boosted by combining it with additive manufacturing. Printing of reverse-engineered elements has become an option particularly when spare parts are needed. In this paper, a case study was presented that explains how such an approach can be implemented in the case of products with asymmetric mechanical properties and using replacement materials. In this case study, a reverse engineering application was conducted on a textile machine spare part. To this end, the nearest material was selected to the actual material selection and some mechanical tests were made to validate it. Next, a replacement part was designed by following the asymmetric push-in pull-out characteristic. Finally, the finite element analysis with Additive Manufacturing was combined and validated experimentally.
Źródło:
Acta Mechanica et Automatica; 2022, 16, 3; 250--258
1898-4088
2300-5319
Pojawia się w:
Acta Mechanica et Automatica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Kefir Prevents Adipose Tissue Growth Through the Induction of Apoptotic Elements in High-Fructose Corn Syrup-Fed Rats
Autorzy:
Aslan, Esra
Sadi, Gokhan
Guzel, Hilal
Karaca, Cigdem
Korkmaz, Omer A.
Pektas, Mine K.
Celegen, Mehmet
Aladag, Tugce
Oncu, Seyma
Pektas, Mehmet B.
Powiązania:
https://bibliotekanauki.pl/articles/16538540.pdf
Data publikacji:
2023-05-05
Wydawca:
Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
Tematy:
adipose tissue
fructose
kefir
apoptosis
inflammation
Opis:
Consumption of high-fructose corn syrup (HFCS) in the diet is a causal factor in the development of abdominal obesity; however, the molecular mechanism behind this association is still up for debate. This study evaluated the metabolic disturbances that are caused by HFCS on adipose tissue as well as the possibility of kefir as a therapy to prevent these metabolic disturbances. Male Wistar rats were divided into four groups: control, kefir, HFCS, and HFCS+kefir. HFCS (20%, w/v) was given in drinking water and kefir (1 mL/100 g body weight) by gastric gavage daily for 8 weeks. Levels of insulin signaling, inflammation, and apoptosis-associated proteins of adipose tissues were determined with Western blot and immunohistochemical techniques. Gene expressions were evaluated with semi-quantitative real-time polymerase chain reaction (qRT-PCR). The indirect terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) method was used to assess changes in apoptotic cells, and hematoxylin/eosin staining to determine adipocyte number and diameter. Accordingly, HFCS boosted protein kinase B (Akt) and p-Akt while reducing nuclear factor κB (NF-κB), and tumor necrosis factor alpha (TNFα) levels and kefir treatment restored Akt induction in HFCS-treated rats despite raising NF-κB, and TNFα. Increased expression of Akt and B-cell lymphoma-2 gene (Bcl2) was contrasted with decreased expression of Nfkb, Tnfa, tumor protein 53 gene (p53), and caspase-8 gene (Casp8). Furthermore, while there was a marked reduction in TUNEL-positive cells in the HFCS group, the number of such cells was greater in the HFCS+kefir group. These results show that HFCS intake suppresses apoptosis in adipose tissues, which may be responsible for tissue development and abdominal obesity and may be reversed with kefir administration due to the activation of apoptosis-associated genes and proteins.
Źródło:
Polish Journal of Food and Nutrition Sciences; 2023, 73, 2; 120-129
1230-0322
2083-6007
Pojawia się w:
Polish Journal of Food and Nutrition Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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