Autor: Akhtar, K. - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Tunnel support design by comparison of empirical and finite element analysis of the Nahakki Tunnel in Mohmand Agency, Pakistan
Autorzy:: Riaz, A.
Jamil, S. M.
Asif, M.
Akhtar, K.
Powiązania:: https://bibliotekanauki.pl/articles/178620.pdf
Data publikacji:: 2016
Wydawca:: Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:: rock mass strength parameters
rock mass classification
FEM analysis
Phase2
tunnel support design
Opis:: The paper analyses the geological conditions of study area, rock mass strength parameters with suitable support structure propositions for the under construction Nahakki tunnel in Mohmand Agency. Geology of study area varies from mica schist to graphitic marble/phyllite to schist. The tunnel ground is classified and divided by the empisical classification systems like Rock mass rating (RMR), Q system (Q), and Geological strength index (GSI). Tunnel support measures are selected based on RMR and Q classification systems. Computer based finite element analysis (FEM) has given yet another dimension to design approach. FEM software Phase2 version 7.017 is used to calculate and compare deformations and stress concentrations around the tunnel, analyze interaction of support systems with excavated rock masses and verify and check the validity of empirically determined excavation and support systems.
Źródło:: Studia Geotechnica et Mechanica; 2016, 38, 1; 75-84
0137-6365
2083-831X
Pojawia się w:: Studia Geotechnica et Mechanica
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 2.

Tytuł:: Comparative analysis of buckling load of circular and corrugated tubes by utilizing key performance indicators
Autorzy:: Rahim, M. R.
Akhtar, S.
Bharti, P. K.
Powiązania:: https://bibliotekanauki.pl/articles/265589.pdf
Data publikacji:: 2017
Wydawca:: Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:: buckling load
tubular structures
quasi-static
key performance indicators (KPIs)
circular and corrugated sections
konstrukcje rurowe
pianka aluminiowa
rura cienkościenna
Opis:: The performance of buckling load of tubular structures under quasi-static axial loading is quite appreciable, numerous tubes of various cross-section have been extensively investigated and corrugated sections have been designed to further improve the performance. In this paper, a carefully designed set of key performance indicators (KPIs) is utilized to assess and compare the buckling load of circular and corrugated tubes. A series of diagrams related to KPIs with various parameters of tubes are presented to demonstrate the influence of sectional configuration on the performance of tubes as well as the effect of the material on the potential of the same. The work is inestimable to engineering designs and applications, and further studies on the buckling load of other configurations.
Źródło:: International Journal of Applied Mechanics and Engineering; 2017, 22, 3; 789-797
1734-4492
2353-9003
Pojawia się w:: International Journal of Applied Mechanics and Engineering
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 3.

Tytuł:: Splenic hydatidosis with abdominal pain – a rare presentation in a developing nation
Autorzy:: Akhtar, Kafil
Alam, Saquib
Rab, Atia Zaka-ur
Sherwani, Rana K
Powiązania:: https://bibliotekanauki.pl/articles/1597352.pdf
Data publikacji:: 2020-03-30
Wydawca:: Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:: abdominal pain
histopathology
hydatidosis
spleen
Opis:: Introduction. Primary extrahepatic hydatid cysts are rare, and primary splenic hydatid cysts even rarer. Splenic hydatidosis constitutes 2% to 3.5% of all hydatid cysts. Aim. To present a case report of splenic hydatidosis with abdominal pain. Description of the case. We report here a case of isolated splenic hydatid cysts in a 23 year old female, who presented with dull dragging pain in the left hypochondrium. Diagnosis was made on computed tomography imaging of the abdomen and microscopic examination of the laminated hydatid cyst wall and supplemented with positive enzyme linked immunosorbent assay for hydatid antibodies. Conclusion. The incidence of splenic involvement by hydatid cysts is very low. Man is an accidental intermediate host, as entry of the larval forms into humans represents an end stage in its life cycle. Until recently the gold standard treatment for splenic hydatidosis was splenectomy, as medical therapy seems to be ineffective. However, the last two decades have shown a tendency towards splenic conservative surgery in suitable cases, to reduce opportunistic post splenectomy infection.
Źródło:: European Journal of Clinical and Experimental Medicine; 2020, 1; 45-48
2544-2406
2544-1361
Pojawia się w:: European Journal of Clinical and Experimental Medicine
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 4.

Tytuł:: Drummondin E and Flinderole B are potential inhibitors of RNA-dependent RNA polymerase of SARS-CoV-2: an in silico study
Autorzy:: Akhtar, N.
Verma, H.
Silkari, O.M.
Upadhyay, A.K.
Kaushik, V.
Mannan, M.A.
Powiązania:: https://bibliotekanauki.pl/articles/2096249.pdf
Data publikacji:: 2022
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: RNA polymerase
SARS-CoV-2
RNA-dependent
Drummondin E
Flinderole B
Opis:: Coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected 235.6 million people worldwide. In the present study, RNA-dependent RNA polymerase (RdRp) (PDB Id: 6M71) of SARS-CoV-2, an essential enzyme needed for subgenomic replication and amplification of RNA, was selected. Similar to other RdRps, it is a conserved protein and a popular target for antiviral drug therapy. Based on a computational approach, potential RdRp inhibitors were identified. The absorption, distribution, metabolism, excretion, and toxicity (ADMET) of selected molecules were determined using computation tools. The potential inhibitors were docked to the RdRp and later confirmed by Molecular Dynamics (MD) using the “Flare” module of Cresset software. Drummondin E and Flinderole B had higher drug similarity scores among the compounds selected in this study. Both these compounds are noncarcinogenic, nonirritant, nontumorigenic, and nonmutagenic. Molecular docking studies showed that both compounds can bind to RdRp. The best ligand interaction patterns were validated by MD using the “Flare” module. MD was performed for the period of 100 ns with the time step of 1 fs. The simulation results suggest that Thr-680, Arg-624, Lys-676, and Val-557 are key interacting partners in the Drummondin E-RdRp complex, while Asp-618, Asp-760, Asp-623, Arg-624, and Asp-761 are the interacting partners in the Flinderole B-RdRp complex. Based on the in silico drug-likeness score; ADMET properties; and molecular simulation result, we surmise that Flinderole B and Drummondin E could impede SARS-CoV-2 genome replication and transcription by targeting the RdRp protein.
Źródło:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2022, 103, 1; 53-70
0860-7796
Pojawia się w:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Informacja

Wyszukujesz frazę "Akhtar, K." wg kryterium: Autor

Źródło danych

Dostawca treści

Kolekcja

Rok wydania

Wydawca

Temat

Autor

Typ dokumentu

Język