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    Wyświetlanie 1-3 z 3
    Tytuł:
    Clinical Manifestations of Plasmodium berghei ANKA Infection in Juvenile Mice: A Short Case Report
    Autorzy:
    Ajayi, J. B.
    Agbeyangi, A. O.
    Daniel, A.
    Omobolaji, I.
    Mogaji, H. O.
    Powiązania:
    https://bibliotekanauki.pl/articles/1113684.pdf
    Data publikacji:
    2017
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    ECM
    Juvenile
    Malaria
    Mice
    Neonates
    Plasmodium berghei
    Opis:
    Malaria is an important health and development challenge in Africa, Animal models most particularly mice, have long been employed to study malaria pathogenesis. This paper describes clinical manifestations due to Plasmodium berghei ANKA infection in juvenile mice as a model for understanding the complications of congenital malaria in neonates. Forty-five juvenile mice (5-7 days old) were acquired from University College Hospital, Ibadan and injected with 2×107 (0.2 ml) Plasmodium berghei ANKA parasitized red blood cells (PRBCs). The mice were then transported to the study site, kept in well-ventilated cages and fed daily with a balanced ration. Post-P. berghei infection, the mice were monitored daily for mortality. Clinical manifestations of experimental cerebral malaria (ECM) were assessed and confirmed if at least ruffled fur, hunching, wobbly gait, limb paralysis, convulsions, or coma was observed. Each sign was given a score of 1. Animals with scores ≥4 were considered to have severe ECM. In the experiment, 20 (44%) mice were lost due to natural cause (i.e. stress) at day 2. Between day 4 and 9, 25 (56%) of the study mice presented clinical signs of ECM. This included: ruffled fur – 25 (100%), hunching - 21 (84%), wobbly gait - 17 (68%), limb paralysis - 20 (80%), convulsions - 25 (100%). Survival rate and severity of ECM in the mice differs, 22 (88.0%) had severe ECM and 3 (12.0%) had mild ECM. This study has shown that parasite establishment and malaria complications can manifest as early as 4 days’ post P. berghei infection in 5-7 days old mice.
    Źródło:
    World News of Natural Sciences; 2017, 14; 90-96
    2543-5426
    Pojawia się w:
    World News of Natural Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Knowledge Attitude and Practices of Caregivers on Management and Treatment of Childhood Malaria in Ogun State, South-Western Nigeria
    Autorzy:
    Agbeyangi, O. A.
    Sam-Wobo, S. O.
    Ekpo, U. F.
    Akinloye, O. A.
    Mafiana, C. F.
    Ajayi, J. B.
    Powiązania:
    https://bibliotekanauki.pl/articles/1179169.pdf
    Data publikacji:
    2017
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Ogun State
    South-western Nigeria
    home management of malaria
    treatment seeking behaviours
    Opis:
    Home management of malaria involves presumptively treating febrile children at clinic or near home with antimalarial drugs distributed by trained members of the community provide medications and educate primary caregivers about treatment of malaria and recognition of severe illness. Structured questionnaires were administered to the parents, health workers and patent medicine vendors to determine acceptability of rectal artesunate and treatment seeking behaviours. Data obtained were analyzed using SPSS version 20 to assess association with p-value of < 0.05. Current first line antimalarial drug for treating childhood malaria at the PHCs was artesunate derivatives (90.3%) with no usage of chloroquine derivatives (0%) and common route of administration was intra-muscular (81.4%) with least usage of rectal (6.2%). Patent medicine vendors showed that the common drug derivatives purchase for treating childhood malaria was chloroquine derivatives (89.2%) with oral (91.9%) as most common route of administration and no awareness of rectal route (0%). Cases of resistance of malaria parasites to anti-malarial drugs, mostly chloroquine derivatives (89.3%) and least with artesunate derivatives (7.1%) observed by health workers. Incomplete dosage (95.6%) and fake drug (84.9%) were described as main factors responsible for malaria parasite resistance. Patent medicine vendors have come across cases of resistance of malaria parasites to anti-malarial drugs mostly chloroquine derivatives (93.2%) with drug abuse (89.2%) and fake drug (82.4%). Treatment of malaria is challenged by inadequate health-care infrastructure and community-based interventions.
    Źródło:
    World Scientific News; 2017, 83; 62-74
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Participatory development of demand-driven curriculum for career-ready e-extension services in Nigeria
    Autorzy:
    Deji, O.F.
    Opayinka, A.O.
    Ajayi, A.O.
    Adesoji, S.A.
    Adisa, B.O.
    Ojo, T.F.
    Alabi, D.L.
    Ayinde, J.O.
    Agboola, A.F.
    Filusi, O.J.
    Oladele, O.I.
    Powiązania:
    https://bibliotekanauki.pl/articles/2081174.pdf
    Data publikacji:
    2021
    Wydawca:
    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie. Wydawnictwo Szkoły Głównej Gospodarstwa Wiejskiego w Warszawie
    Tematy:
    participatory curriculum
    career- ready
    e- extension services
    stakeholders
    Nigeria
    Opis:
    This paper described and contextualized participatory development of demand-driven curriculum for career-ready e-extension services in Nigeria as introduced by the Sasakawa Africa Fund for Extension Education. The stages of participatory development were participatory need assessment, participatory stakeholders’ workshop and validation among 124 stakeholders selected as key informants in relation to agricultural extension training, delivery, end users and policy makers. The stakeholders were grouped as follows: community leaders and policy makers; extension agencies / organisations / institutions / employers; farmers; input suppliers / marketers / agro-based traders / other value actors; and potential candidate groups. Stakeholder meetings were held separately with different groups three times, and then a combined meeting took place. The aggregated major decisions/consensus were subjected to content analysis using ATLAS.ti. The validation process included reading of each agreed decision to all participants, then participants indicated their agreement or otherwise, which led to either rejection or acceptance of the decision. This paper concludes that participatory curriculum development has enhanced the stakeholders to identify areas of demand-driven training in response to community needs. The stakeholders preferred more online than face-to-face training. The major perceived advantages of e-extension were reduced risk, time and cost effectiveness while infrastructural and human challenges were the perceived challenges that could possibly hinder the smooth running of eextension.
    Źródło:
    Zeszyty Naukowe Szkoły Głównej Gospodarstwa Wiejskiego w Warszawie. Problemy Rolnictwa Światowego; 2021, 21[36], 3; 14-23
    2081-6960
    Pojawia się w:
    Zeszyty Naukowe Szkoły Głównej Gospodarstwa Wiejskiego w Warszawie. Problemy Rolnictwa Światowego
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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