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    Wyświetlanie 1-4 z 4
    Tytuł:
    SYNTHESIS, AND EVALUATION OF COUMARIN HYBRIDS AS ANTIMYCOBACTERIAL AGENTS
    Autorzy:
    Hassan, Mohd Z.
    ALSAYARI, ABDULRHMAN
    OSMAN, HASNAH
    ALI, MOHAMED A.
    MUHSINAH, ABDULLATIF B.
    AHSAN, MOHAMED J.
    Powiązania:
    https://bibliotekanauki.pl/articles/895509.pdf
    Data publikacji:
    2019-12-29
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    cytotoxicity
    Coumarin
    TB
    Thiazolopyrimidine
    HTS
    antimycobacterial
    Opis:
    A series of twelve hybrid coumarin analogues were synthesized and screened through HTS for their antimycobacterial activity against Mtb H37Rv. The hybrid molecules were efficiently synthesized by the reactions of 3-(bromoacetyl)coumarin with Biginelli products 2-mercapto-6-oxo-4-aryl-1,6-dihydropyrimidine-5-carbonitriles. Of the resulting twelve hybrids, the two compounds 7-(2,4-dichlorophenyl)-5-oxo-3-(2-oxo-2H-chromen-3-yl)-5H-thiazolo[3,2-a] pyrimidine-6-carbonitrile (3d) and 7-(4-nitrophenyl)-5-oxo-3-(2-oxo-2H-chromen-3-yl)-5H-thiazolo[3,2-a]pyrimidine-6-carbonitrile (3f) showed excellent antimycobacterial activity against Mtb (EC50 3.19 & 7.91 µM, respectively) and low cytotoxicity against the VERO cell line (IC50 > 62.5 µg/mL).
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 6; 1029-1036
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Behavior and failure tracking of structural elements using applied element method
    Autorzy:
    Badawy, Mahmoud Mohamed
    Mustafa, Suzan Ali A.
    Bakry, Atef Eraky
    Powiązania:
    https://bibliotekanauki.pl/articles/35561246.pdf
    Data publikacji:
    2022
    Wydawca:
    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie. Wydawnictwo Szkoły Głównej Gospodarstwa Wiejskiego w Warszawie
    Tematy:
    applied element method
    AEM
    numerical analysis
    stiffness matrix
    large deformation failure tracking
    Opis:
    Applied element method (AEM) is a recently displacement-based structural analysis method. It provides the benefits of both the finite element method (FEM) and the discrete element method (DEM). This method relies on those structures are segmented into rigid elements linked by normal and shear springs. In this paper a brief note of the AEM is given. Then, using the AEM, a 2D MATLAB open source program was created to analyze different structures with varied boundary conditions and to permit researchers for enhancing the method. The proposed program was verified using linear elastic analysis and large deformation static analysis. The influence of element size and the number of connecting springs between elements was studied. Finally, the proposed program was capable of tracking failed elements and their spread. In addition, the program could predict deflection values and structure deformed shape.
    Źródło:
    Scientific Review Engineering and Environmental Sciences; 2022, 31, 3; 203-222
    1732-9353
    Pojawia się w:
    Scientific Review Engineering and Environmental Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Assessment of Lower Zab river water quality using both Canadian Water Quality Index Method and NSF Water Quality Index Method
    Autorzy:
    Ahmed, Sarah M.
    Taha, Omer M.E.
    Najemalden, Mohamed A.
    Ahmed, Rehab T.
    Abedulwahab, Ali A.
    Powiązania:
    https://bibliotekanauki.pl/articles/118599.pdf
    Data publikacji:
    2020
    Wydawca:
    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie. Wydawnictwo Szkoły Głównej Gospodarstwa Wiejskiego w Warszawie
    Tematy:
    NSF Water Quality Index
    Canadian Water Quality Index
    Lower Zab river
    physicochemical parameters
    dissolved oxygen
    biochemical oxygen demand
    Opis:
    Rivers are considered the most important sources of surface water on Earth. They are play a significant role in all human activities and the quality of river water is needed. Therefore, the importance of the water quality index is arising through providing data base about quality of the water source, and explain the change in the water quality over a period of time continually. This study involved determination of physicochemical and biological parameters of Lower Zab river in Kirkuk city at two different points. The objectives of the study are to assess the present water quality, through analysis of some selected water quality parameters like pH, TDS, BOD, dissolved oxygen, turbidity, EC, alkalinity, and salinity etc. and to compare the results with the Canadian Council of Ministers of the Environment and National Sanitation Foundation Water Quality Indices. Raw water samples were collected from the Lower Zab river twice a month by one sample every 15 days from each station. The water quality data include 16 different parameters. Tests were carried out following the American Public Health Association standard methods. The results show that all parameters values were within the standards of drinking water proposed by the CCME standards and Iraqi standards or the World Health Organization standards for drinking purpose, except turbidity, DO, nitrate, calcium, which were mostly higher than the standards and sometimes BOD and potassium. The results of WQI showed that the water quality at LZ3 station is lower than LZ2 station due to the polluting activity of the Lower Zab river. Furthermore, for the years 2014, 2015, and 2016, the water quality was degraded due to the ISIS war. Also, it was noted in the 2013 year that the water quality degraded more in fall and winter seasons due to that the earth has exposed to the long-dried season and then suddenly exposed to a high rainfall season which in turns leads to increase some parameters very high (i.e. turbidity). Finally, the Lower Zab river water cannot be use for drinking directly. However, a pretreatment is needed before the drinking use.
    Źródło:
    Scientific Review Engineering and Environmental Sciences; 2020, 29, 2; 155-171
    1732-9353
    Pojawia się w:
    Scientific Review Engineering and Environmental Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Production of bioactive metabolites from different marine endophytic Streptomyces species and testing them against methicillin-resistant Staphylococcus aureus (MRSA) and cancer cell lines
    Autorzy:
    El-Gendy, M.M.A.A.
    Mohamed, Z.K.
    Hekal, N.Z.
    Ali, F.M.
    Yousef, A.E.M.
    Powiązania:
    https://bibliotekanauki.pl/articles/81078.pdf
    Data publikacji:
    2018
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    Staphylococcus aureus
    infection
    methicillin-resistant Staphylococcus aureus
    endophyte
    Streptomyces
    bioactive metabolite
    Actinomycetes
    marine invertebrate
    anticancer activity
    cancer cell line
    lung cancer
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2018, 99, 1
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-4 z 4

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