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Tytuł:
Transforming growth factor β1 protein and mRNA levels in inflammatory bowel diseases: towards solving the contradictions by longitudinal assessment of the protein and mRNA amounts
Autorzy:
Liberek, Anna
Kmieć, Zbigniew
Wierzbicki, Piotr
Jakóbkiewicz-Banecka, Joanna
Liberek, Tomasz
Łuczak, Grażyna
Plata-Nazar, Katarzyna
Słomińska-Frączek, Magdalena
Kaszubowska, Lucyna
Gabig-Cimińska, Magdalena
Węgrzyn, Alicja
Powiązania:
https://bibliotekanauki.pl/articles/1039466.pdf
Data publikacji:
2013
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Crohn's disease
ulcerative colitis
Transforming Growth Factor-β1
longitudinal assessment of TGF-β1 level
Opis:
Previously published studies on levels of the transforming growth factor-β1 (TGF-β1) protein and mRNA of the corresponding gene in patients suffering from inflammatory bowel diseases (IBD) gave varying results, leading to contradictory conclusions. To solve the contradictions, we aimed to assess longitudinally TGF-β1 protein and mRNA levels at different stages of the disease in children suffering from IBD. The study group consisted of 19 pediatric patients with IBD at the age between 3.5 and 18.4 years. The control group consisted of 42 children aged between 2.0 and 18.0 years. The plasma TGF-β1 concentration was measured with ELISA. mRNA levels of the TGF-β1 gene isolated from samples of the intestinal tissue were assessed by reverse transcription and real-time PCR. Levels of TGF-β1 protein in plasma and corresponding mRNA in intestinal tissue were significantly higher in IBD patients than in controls. TGF-β1 and corresponding transcripts were also more abundant in plasma and intestinal tissue, respectively, in patients at the active stage of the disease than during remission. In every single IBD patient, plasma TGF-β1 level and mRNA level in intestinal tissue was higher at the active stage of the disease than during remission. Levels of TGF-β1 and corresponding mRNA are elevated during the active stage of IBD but not during the remission. Longitudinal assessment of this cytokine in a single patient may help to monitor the clinical course of IBD.
Źródło:
Acta Biochimica Polonica; 2013, 60, 4; 683-688
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The use of computer programs to solve ventilation issues in Vietnamese coal mines
Wykorzystanie programów komputerowych do rozwiązywania problemów wentylacyjnych w wietnamskich kopalniach węgla
Autorzy:
Bui, Hoa
Życzkowski, Piotr
Łuczak, Rafał
Powiązania:
https://bibliotekanauki.pl/articles/318979.pdf
Data publikacji:
2019
Wydawca:
Polskie Towarzystwo Przeróbki Kopalin
Tematy:
wentylacja
kopalnie
Wietnam
ventilation
coal mines
Vietnam
Opis:
Having enjoyed an economic upsurge in recent years, Vietnam is now recording increased demand for electrical energy. Its production, for the most part, relies on the coal mining industry, thus resulting in a strong upward trend in mining volumes. Being geologically complex, Vietnamese mines are characterised by a complicated structure of their headings. The local ventilation systems are also affected by there being very few automatic dams and an by increases in airflows delivered to the mine. For this reason, in order to analyse airflows and maintain the proper control of ventilation systems, computer software is required. The article offers a comparison of computer programs – Kazemaru, VentGraph and VentSim – as employed for use in Vietnamese mines. The assessment covered the manner in which these programs are used and how their output data are presented, as well as their range of applications in the conditions of Vietnamese coal mines.
Źródło:
Inżynieria Mineralna; 2019, 21, 2/2; 119-128
1640-4920
Pojawia się w:
Inżynieria Mineralna
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Stan kadry medycznej w Polsce – kto nas będzie leczył w przyszłości?
Condition of Medical Staff in Poland – Who Will Treat Us in the Future?
Autorzy:
Wasilewski, Piotr
Łuczak, Julita
Powiązania:
https://bibliotekanauki.pl/articles/417093.pdf
Data publikacji:
2016-10
Wydawca:
Najwyższa Izba Kontroli
Tematy:
medical staff
medical services
doctor
nurse
treatment
population
demographic changes
Opis:
Doctors and other representatives of medical professions play a special role in a society, as they are entrusted with people’s health which is one of the greatest goods of a human. Surveys conducted in various systems of healthcare related to the satisfaction of persons with chronic health problems show that the main source of problems is the medical staff rather than the degree of advancement of medical technologies available. Therefore, appropriate – in accordance with the expectations of the society – education of medical staff should constitute a very important element of the health protection system. The Supreme Audit Office, taking the above in consideration, has conducted a coordinated audit of this matter.
Źródło:
Kontrola Państwowa; 2016, 61, 5 (370); 63-77
0452-5027
Pojawia się w:
Kontrola Państwowa
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Selection and calculation of air cooling solutions in underground coal mines in Vietnam
Dobór i obliczenia rozwiązań chłodzenia powietrza w podziemnych kopalniach węgla w Wietnamie
Autorzy:
Borowski, Marek
Trung Tien, Quan
Łuczak, Rafał
Życzkowski, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1841452.pdf
Data publikacji:
2020
Wydawca:
Polskie Towarzystwo Przeróbki Kopalin
Tematy:
air temperature
air humidity
air cooling
thermal power of cooler
temperatura powietrza
wilgotność powietrza
chłodzenie powietrza
moc cieplna chłodnicy
Opis:
Currently, Vietnamese underground mines have been exploited down to -500 m and, in the near future, they will be exploited deeper. The exploitation of coal of seams has an negative impact on a workers environment. The increase in the depth of coal seam exploitation causes is the increase of adverse microclimate factors such as temperature, moisture, heat radiation. According to the current Viet¬namese laws, coal deposits can be mined in a condition when air temperature does not exceed 30oC, although this rule is not always observed, especially during summer. The article show how reducing the adverse impact of climate factors in the mines and calculating the parameters which reduce the temperature on an example in one of underground coal mines in Vietnam.
Obecnie wietnamskie kopalnie podziemne zostały wyeksploatowane do -500 m, w najbliższej przyszłości będą eksploatowane głębiej. Eks¬ploatacja ma negatywny wpływ na środowisko. Działalność eksploatacji w wyrobiskach powoduje wzrost niekorzystnych czynników mi-kroklimatycznych, takich jak temperatura, wilgotność, promieniowanie cieplne. Zgodnie z obowiązującym wietnamskim prawem, złoża węgla mogą być eksploatowane w warunkach, gdy temperatura powietrza nie przekracza 30°C, chociaż nie zawsze jest to przestrzegane, zwłaszcza latem. W artykule przedstawiono rozwiązanie ograniczania niekorzystnego wpływu czynników klimatycznych w kopalniach oraz obliczenie parametrów obniżających temperaturę powietrza na przykładzie podziemnych kopalń węgla w Wietnamie.
Źródło:
Inżynieria Mineralna; 2020, 2, 2; 237-244
1640-4920
Pojawia się w:
Inżynieria Mineralna
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Neuromorphic approach for breathing rate monitoring using data produced by FMCW radar
Autorzy:
Ślot, Krzysztof
Łuczak, Piotr
Hausman, Sławomir
Powiązania:
https://bibliotekanauki.pl/articles/2173715.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
neuromorphic architectures
analog computing
FMCW radar
vital parameter estimation
architektura neuromorficzna
obliczenia analogowe
radar FMCW
ocena parametrów życiowych
Opis:
The paper introduces a neuromorphic computational approach for breathing rate monitoring of a single person observed using a Frequency-Modulated Continuous Wave radar. The architecture, aimed at implementation in analog hardware to ensure high energy efficiency and to provide system operation longevity, comprises two main functional modules. The first one is a data preprocessing unit aimed at the extraction of information relevant to the analysis objective, whereas the second one is a pre-trained recurrent neural regressor, which analyzes sequences of incoming samples and estimates the breathing rate. To ensure compatibility with neural processing and to achieve simplicity of underlying resources, several solutions were proposed for the data preprocessing module, which provides range-wise space segmentation, selection of a bin of interest (comprising the dominant motion activity), and delivery of data to regressor inputs. To implement these functions, we introduce an appropriate chirp frequency modulation scheme, apply a neuromorphic filtering procedure and use a Winner-Takes-All network for extracting information from the bin of interest. The architecture has been experimentally verified using a dataset of indoor recordings supplied with reference data from a Zephyr BioHarness device. We show that the proposed architecture is capable of making correct breathing rate estimates while being feasible for analog implementation. The mean squared regression error with respect to the Zephyr-produced reference values is approximately 3.3 breaths per minute (with a deviation of ±0:27 in the 95% confidence interval) and the estimates are produced by a recurrent, GRU-based neural regressor, with a total of only 147 parameters.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2022, 70, 6; art. no. e143552
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Model biznesu wykorzystujący otwartość na współpracę – wdrożenie koncepcji Internet of Things przez firmę Samsung
Autorzy:
Łuczak, Miłosz
Senkus, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1826531.pdf
Data publikacji:
2019-08-01
Wydawca:
Uniwersytet Przyrodniczo-Humanistyczny w Siedlcach
Tematy:
model biznesu
open innovation
relacje z otoczeniem
Internet of Things
Opis:
Dynamika zmian współczesnego otoczenia sprawia, że przedsiębiorstwa muszą poszukiwać stale nowych metod utrzymywania swojej przewagi konkurencyjnej. Obecnie, istotnym czynnikiem jest wykorzystanie technologii informatycznych ułatwiających nawiązywanie i utrzymywanie kontaktów z innymi podmiotami. Zgodnie z koncepcją open innovation, otwartość na współpracę może przyczyniać się do powstawania tzw. wartości dodanej. Przewaga konkurencyjna współcześnie nie wynika więc z zabezpieczenia swoich kluczowych zasobów a z umiejętności ich współdzielenia i współwykorzystania. Artykuł przedstawia ilustrację modelu biznesowego wykorzystującego koncepcję open innovation na przykładzie wdrażania Internet of Things przez firmę Samsung Electronics, który został określony na podstawie badań aktywności firmy Samsung Electronics oraz doniesień portali branżowych. Artykuł ten jest częścią szerszych badań nad wykorzystaniem IoT w modelach biznesowych współczesnych organizacji.
Źródło:
Zeszyty Naukowe Uniwersytetu Przyrodniczo-Humanistycznego w Siedlcach; 2016, 38, 111; 181-198
2082-5501
Pojawia się w:
Zeszyty Naukowe Uniwersytetu Przyrodniczo-Humanistycznego w Siedlcach
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Method of Air Temperature Forecast in Mechanized Longwall Workings in the Conditions of Vietnamese Mines
Autorzy:
Truong, Tien Quan
Łuczak, Rafał
Życzkowski, Piotr
Borowski, Marek
Powiązania:
https://bibliotekanauki.pl/articles/2020186.pdf
Data publikacji:
2021
Wydawca:
Polskie Towarzystwo Przeróbki Kopalin
Tematy:
climatic conditions
temperature forecasting
statistical data analysis
warunki klimatyczne
prognozy
temperatura
statystyka
Opis:
In the most recent years, the Vietnam National Coal - Mineral Industries Holding Corporation Limited (VINACOMIN) has been dynamically developing mechanization technologies in underground coal mines. The climatic conditions of Vietnam, as well as increasing the depth of the coal seams and the production capacity, contribute to an air temperature increasing in mining excavations. The article presents statistical equations enabling air temperature forecasting at the outlet of mechanized longwall workings. The results of numerical calculations, obtained from the solutions of the adopted mathematical descriptions, were compared with the measurement results and the statistical significance of the obtained deviations was determined. The performed analysis allowed to assess the practical usefulness of the adopted model for the air temperature forecasting in the workings of mechanized underground mines in Vietnam. The presented method can be used as a tool for mining services in the fight against the climate threat in underground excavations.
Źródło:
Inżynieria Mineralna; 2021, 2; 353--364
1640-4920
Pojawia się w:
Inżynieria Mineralna
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Human–robot cooperation in sorting of randomly distributed objects
Autorzy:
Jezierski, Edward
Łuczak, Piotr
Smyczyński, Paweł
Zarychta, Dariusz
Powiązania:
https://bibliotekanauki.pl/articles/229240.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
human–robot cooperation
vision system
collaborative robots
Opis:
The paper presents the possibilities of teaching a robot controller to perform operations of autonomous segregation of objects differing in features that can be identified using a vision system. Objects can be arranged freely on the robot scene also covered with others. In the learning phase, a robot operator presents the segregation method by moving subsequent objects held in a human hand, e. g. a red object to container A, a green object to container B, etc. The robot system, after recognizing the idea of segregation that is being done using the vision system, continues this work in an autonomous way, until all identified objects will be removed from robotic scene. There are no restrictions on the dimensions, shapes and placement of containers collecting segregated objects. The developed algorithms were verified on a test bench equipped with two modern robots KUKA LBR iiwa 14 R820.
Źródło:
Archives of Control Sciences; 2019, 29, 4; 603-615
1230-2384
Pojawia się w:
Archives of Control Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Helicobacter pylori increases expression of proapoptotic markers Fas and FasL on CD4 lymphocytes in children
Autorzy:
Kotłowska-Kmieć, Aldona
Bąkowska, Alicja
Szarszewski, Adam
Kamińska, Barbara
Łuczak, Grażyna
Radys, Wojciech
Landowski, Piotr
Brodzicki, Jacek
Korzon, Maria
Liberek, Anna
Powiązania:
https://bibliotekanauki.pl/articles/1040535.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
T cell
H. pylori
FasL
Fas
apoptosis
lymphocyte
Opis:
The pathomechanism of Helicobacter pylori action upon gastric mucosa and its role in the pathogenesis of gastritis have not been fully elucidated. The aim of this study was to evaluate the most prevalent lymphocyte subpopulations of the gastric mucosa in gastritis in children, as well as to evaluate the expression of Fas and Fas ligand receptors (FasL), periapoptotic markers of gastric mucosa lymphocytes before and after H. pylori eradication. Forty nine patients aged 6 to 17 years, investigated due to chronic abdominal pain, were studied. The obtained tissue samples were analysed by immunohistochemistry. Different lymphocyte subsets were quantified on the basis of surface antigen expression (CD3, CD4, CD8, CD20), secreted cytokines (IL-4, IL-6, IFNγ) and Fas and FasL proteins in the gastric mucosa. B and T helper lymphocytes were found to play a major role in the inflammatory infiltration in the gastric mucosa in children during H. pylori infection. Their expression was found to decrease after eradication. The enhanced expression of Fas receptor on lymphocytes before treatment and a decrease of this expression after eradication of H. pylori were shown. It was demonstrated that there is a correlation between CD4 and Fas receptor expression that may induce apoptosis of the helper lymphocytes in infected children.
Źródło:
Acta Biochimica Polonica; 2009, 56, 3; 433-438
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Geobotaniczno-sozologiczna waloryzacja siedlisk przyrodniczych na wybranych fragmentach Błękitno-Zielonej Sieci
Geobotanical and sozological valorization of natural habitats in selected areas of the Blue-Green Network
Autorzy:
Łuczak, Marcin
Witosławski, Piotr
Andrzejewski, Hieronim
Kiedrzyński, Marcin
Kurowski, Józef K
Powiązania:
https://bibliotekanauki.pl/articles/970743.pdf
Data publikacji:
2006
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Tematy:
geobotanical and sozological valorization
environment protection
Blue-Green Network concept
waloryzacja geobotaniczno-sozologiczna
ochrona przyrody
koncepcja Błękitno-Zielonej Sieci
Opis:
One of the key components of The Blue-Green Network in Łódź are valuable natural areas like the relicts of the natural wildlife (called “Green Treasures of Łódź”) which parts have been preserved in Łódź in spite of two hundred years, very intense urbanization processes. The result of years of geobotanical research in the city was establishing 23 areas of nature protection and proposing of 12 additional natural areas which need to be protected (8 areas of landscape protection and 4 ecological sites). Existing and proposed areas of nature protection, including river valleys, build the wildlife system of Łódź. Predominantly the important role in this concept play the Łódź’s river valleys with their vegetation potential. The Sokolowka River Valley which is located in the Northern-West part of Łódź was the exemplary research field for geobotanical and sozological valorization of the natural habitat of the Blue-Green Network. Within the Sokolowka valley there are retained fragments of precious nature ecosystems.
Źródło:
Acta Universitatis Lodziensis. Folia Biologica et Oecologica; 2006, Supplementum; 27-42
1730-2366
2083-8484
Pojawia się w:
Acta Universitatis Lodziensis. Folia Biologica et Oecologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Fostering A Multi-level Approach to Entrepreneurial Pedagogy: The German Experience
Autorzy:
Łuczak-Trąpczyńska, Magdalena
Trąpczyński, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1197785.pdf
Data publikacji:
2017-06-08
Wydawca:
Akademia Ignatianum w Krakowie
Tematy:
entrepreneurial pedagogy
entrepreneurial education
Germany
Opis:
RESEARCH OBJECTIVE: The aim of this paper is to analyse the case of entrepreneurial pedagogy in Germany at the level of primary and secondary education and to identify good practices in the development of entrepreneurship skills of pupils. THE RESEARCH PROBLEM AND METHODS: The paper uses a systematic review of literature with relation to entrepreneurial education, as well as the German literature of the topic, in order to descend to the analysis of secondary data related to the German education system and its usage of entrepreneurial pedagogy. THE PROCESS OF ARGUMENTATION: In the first part, the paper clarifies the notion of entrepreneurial pedagogy and introduces modern didactic approaches, particularly process-oriented teaching. Subsequently, the German case is used to analyse how entrepreneurial pedagogy can be implemented at different interrelated levels. In the recommendation section, the success factors of the implementation of such an approach are discussed. The paper ends with some concluding remarks. RESEARCH RESULTS: The analysis of entrepreneurial pedagogy in German literature and practice highlights the relevance of an interplay of solutions at different levels: the level of the state (or, in the case of decentralised educational systems like the German one, at the regional level), the level of school initiative, as well as the individual level of educators who are in charge of implementing entrepreneurial teaching methods. CONCLUSIONS, INNOVATIONS AND RECOMMENDATIONS: According to the concept of process-oriented didactics presented in this paper, the aspect of making mistakes is an important engine of learning, as well as teaching itself. However, it can be observed in Germany that in teaching reality more attention is devoted to the errors themselves than to the tolerance of errors, according to the principle that the teacher does not commit mistakes. Hence, this issue should be raised in appropriate teacher training. The German experience can be a starting point for discussion related to other countries, as well. 
Źródło:
Horyzonty Wychowania; 2017, 16, 37; 129-146
1643-9171
2391-9485
Pojawia się w:
Horyzonty Wychowania
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 22

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