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Wyświetlanie 1-15 z 15
Tytuł:
Stokes flow in lid-driven cavity under inclined magnetic field
Autorzy:
Gürbüz-Çaldag, M.
Çelik, E.
Powiązania:
https://bibliotekanauki.pl/articles/38695704.pdf
Data publikacji:
2022
Wydawca:
Instytut Podstawowych Problemów Techniki PAN
Tematy:
radial basis function
MHD
Stokes flow
inclination angle
Opis:
Stokes flow in a lid-driven cavity under the effect of an inclined magnetic field is studied. The radial basis function (RBF) approximation is employed to the magnetohydrodynamic (MHD) equations which include Navier-Stokes equations of fluid dynamics and Maxwell’s equations of electromagnetics through Ohm’s law with the Stokes approximation. Numerical results are obtained for the moderate Hartmann number (0 ≤ M ≤ 80) and different angles of a magnetic field (0 ≤ α ≤ π). It is found that the increase in the Hartmann number causes the development of new vortices under the main flow due to the impact of a magnetic field. However, the type of the inclination angle (acute or obtuse) determines the location of the vortices.
Źródło:
Archives of Mechanics; 2022, 74, 6; 549-564
0373-2029
Pojawia się w:
Archives of Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of Post-Heat Treatment on Microstructure and Mechanical Properties of Cu-Fe-Co Powder Alloy Fabricated by Hot Pressing
Autorzy:
Çelik, E.
Aslan, A. K.
Powiązania:
https://bibliotekanauki.pl/articles/353200.pdf
Data publikacji:
2018
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
diamond cutting tools
Cu-Fe-Co alloy
powder metallurgy
hot pressing
heat treatment
Opis:
In this study, the powder mixture which consists of Cu-Fe-Co was produced by using the method of hot pressing technique. In addition, effect of heat treatment process on microstructure and mechanical properties of this alloy was investigated. Following the hot pressing process applied on the samples, heat treatment was carried out at 950°C for two different dwelling times (90 and 180 minutes). Measured density values were considered as physical characteristics, while hardness and fracture strength values were considered as mechanical characteristics. It was observed that porosity rates of hot pressed samples were decreased by increasing of temperature and pressing parameters. In this study it was observed that Cu was spread in matrix and filled the micro porosities. Hardness values were determined to be decreased as a result of grain growth after heat treatment process. That 4 fold increased elongation % values which were achieved by TRS experiments were observed as well.
Źródło:
Archives of Metallurgy and Materials; 2018, 63, 1; 371-377
1733-3490
Pojawia się w:
Archives of Metallurgy and Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis and Characterization of Gd₂O₂SO₄:Pr⁺³ Scintillation Material Produced by Sol-Gel Process for Digital Imaging System
Autorzy:
Aritman, I.
Yildirim, S.
Kisa, A.
Guleryuz, L.
Yurddaskal, M.
Dikici, T.
Celik, E.
Powiązania:
https://bibliotekanauki.pl/articles/1033327.pdf
Data publikacji:
2017-01
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
78.55.Hx
Opis:
Scintillation materials are widely used in digital X-ray imaging applications, radiotherapy applications coupled with suitable photoreceptors. Gd₂O₂SO₄ (GOS) scintillator doped with trivalent praseodymium (Pr⁺³) presented high X-ray absorption properties and good spectral compatibility which were utilized extensively for imaging system of X-ray microscopy, soft X-ray phosphor screen for water window. In this study, GOS:0.01Pr⁺³ scintillation material was synthesized by unique sol-gel process which was not previously applied and its characterization properties were investigated. Structure and luminescence properties of GOS:Pr⁺³ were optimized by utilizing X-ray diffraction, X-ray photoelectron spectroscopy, scanning electron microscopy, and luminescence spectroscopy.
Źródło:
Acta Physica Polonica A; 2017, 131, 1; 106-108
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Variation of biochemical content in the almonds of the endemic Argan tree (Argania spinosa (L.) Skeels) populations in Morocco
Autorzy:
Ayan, S.
Abdaloğlu, G.
Laaribya, S.
Turfan, N.
Çelik, E.N.Y.
Ouhaddou, H.
Alaoui, A.
Powiązania:
https://bibliotekanauki.pl/articles/29430778.pdf
Data publikacji:
2023
Wydawca:
Polska Akademia Nauk. Instytut Dendrologii PAN
Źródło:
Dendrobiology; 2023, 90; 47-57
1641-1307
Pojawia się w:
Dendrobiology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Immunological harmony: the role of magnesium in the development of euthyroid Hashimoto’s thyroiditis
Autorzy:
Celik, E.
Celik, M.
Bulbul, B.Y.
Andac, B.
Okur, M.
Colak, S.Y.
Yekdes, A.C.
Powiązania:
https://bibliotekanauki.pl/articles/53363878.pdf
Data publikacji:
2024
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
Opis:
Magnesium is a trace element that is closely linked to thyroid function and autoimmune thyroiditis. Numerous chronic disorders are also linked to low serum magnesium levels; however, it is unclear how its level relates to the development of autoimmune thyroiditis. In the present study, we evaluated the relationship between Hashimoto’s thyroiditis (HT) and serum magnesium levels in 104 patients: 52 with low and 52 with normal serum magnesium levels. Patient records were retrospectively evaluated and the demographic data, serum levels of thyroid-stimulating hormone, anti-thyroid peroxidase antibody (TPOAb), anti-thyroglobulin antibody (TGAb) and serum magnesium levels were recorded. Patients with low magnesium levels were found to have higher levels of TPOAb, TGAb and radiological evidence of HT when compared to those with normal magnesium levels (P = 0.001, P = 0.007, and P = 0.001, respectively). In logistic regression analysis, ultrasonographic HT findings were found to be significantly more common in the magnesium deficient group (P = 0.001). The serum magnesium level of 0.72 mmol L-1 was determined to be the appropriate cut-off point for the presence of HT ultrasonographic findings with 68.9% sensitivity and 64.4% specificity. As a result, in the present study, low serum magnesium levels were found to be associated with significantly higher incidence of ultrasonographic findings of HT, which may suggest that adequate magnesium supplementation may be an independent protective factor against Hashimoto’s Thyroiditis.
Źródło:
Journal of Elementology; 2024, 29, 2; 367-378
1644-2296
Pojawia się w:
Journal of Elementology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
An Efficient Inductive Coil Link Design for Wireless Power Transfer to Visual Prostheses
Autorzy:
Celik, M.
Aydin, E.
Powiązania:
https://bibliotekanauki.pl/articles/1031436.pdf
Data publikacji:
2017-09
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
wireless power transfer
inductive link
magnetic field
telemetry
visual prosthesis
Opis:
Powering therapeutic devices plays a crucial role in the design phase of implantable electronic units. Batteries could not provide sufficient charge storage, used for the lifetime of the device, considering the space available for them. As sophisticated surgical procedures are required with the possible trauma to the patient such as material discrepancy and tissue damage, replacement is quite risky and not an option. Thus, therapeutic devices, especially visual prostheses, receive power wirelessly through inductive coil links which are connected to a battery outside the body. An inductive link is based on the main principle that there are two components such as primary and secondary units. Although primary unit includes the battery outside the body, power transmitter, and control unit, secondary unit under the skin contains amplifier, rectifier regulators, and power control unit. In this study, an inductive coil link is modelled to evaluate fundamental design specifications for visual prostheses. Inductive coil link parameters are quantitatively investigated so that maximum power transfer efficiency and miniaturization, which are critically important for electronics placed in intraocular region, are provided. Considering 20 mm distance, it is concluded that the separation and the size of the coil pair, loop diameter, frequency have a major role to determine the system performance.
Źródło:
Acta Physica Polonica A; 2017, 132, 3; 535-537
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of Loop LengtH and Nozzle Type on Structural and Performance Properties of Single Jersey Knitted Fabrics
Wpływ długości pętli i typy dyszy na strukturalne właściwości dzianin lewo-prawych
Autorzy:
Çoruh, E
Çelik, N
Powiązania:
https://bibliotekanauki.pl/articles/233973.pdf
Data publikacji:
2014
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Biopolimerów i Włókien Chemicznych
Tematy:
nozzle type
single jersey
knitted fabric
bursting strength
pilling resistance
strukturalne właściwości dzianin
typ dyszy
pojedynczy dżersej
dzianina
pęknięcie
odporność na pilling
Opis:
We studied the structural properties, bursting strength and pilling properties of single jersey knitted fabrics made from OE rotor spun yarns. Raw material of 100% cotton of the Urfa region of Turkey was specifically handled in the study. The yarns were produced with different nozzle types with a yarn of linear density of 19.67 tex. Five different ceramic nozzles were used in yarn production. These nozzle types are known as K4KK, K4KS, K6KF, K8KK & KSNX. Fabrics were produced by a 28 gauge 32 inch diameter circular knitting machine. The yarns were processed to single jersey knitted fabrics by adjusting the yarn loop length between 14 - 17 cm on the machine as they were the minimum and maximum values limited by the yarn type, machine and commercially accepted conditions. The purpose of this paper was to investigate the effect of fabric density and nozzle type on the structural and performance properties of single jersey knitted fabrics investigated in both a grey and dyed state. In addition, results were interpreted statistically and regression equations obtained.
Badano strukturalne właściwości dzianin, wytrzymałość na rozerwanie i pilling dzianin lewo-prawych wykonanych z przędz rotorowych. Stosowano surowiec w postaci 100% bawełny z regionu Urfa w Turcji. Przędze o masie liniowej 19,7 tex produkowano stosując 5 różnych typów dysz ceramicznych. Zastosowano cylindryczną maszynę dziewiarską. Dzianiny produkowano ustalając różne długości pętli w granicach od 14-17 cm wynikających ze stosowanych warunków technicznych. Dzianiny badano w stanie surowym i barwionym. Wszystkie wyniki były analizowane statystycznie.
Źródło:
Fibres & Textiles in Eastern Europe; 2014, 1 (103); 62-67
1230-3666
2300-7354
Pojawia się w:
Fibres & Textiles in Eastern Europe
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Influence of Nozzle Type on Yarn Quality in Open-End Rotor Spinning
Wpływ rodzaju dyszy na jakość przędz w przędzeniu rotorowym
Autorzy:
Çoruh, E.
Çelik, N.
Powiązania:
https://bibliotekanauki.pl/articles/234290.pdf
Data publikacji:
2013
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Biopolimerów i Włókien Chemicznych
Tematy:
rotor spinning
nozzle type
yarn quality
yarn evenness
yarn hairiness
yarn tenacity
przędzenie rotorowe
rodzaj dyszy
jakość przędzy
równość przędzy
wytrzymałość przędzy
Opis:
In this study we investigated the effect of the nozzle type as one of the most important parts of the open-end rotor spinning system on yarn quality. 100% Urfa Region cotton was used for the production of yarns of 20 tex. Experimental studies were made on ten spinning units of a Rieter R1 machine. Five different ceramic nozzle types were used: K4KK (plain with 4 grooves), K4KS (plain with 4 grooves and aggressive flute insert), K6KF (plain with 6 grooves), K8KK (plain with 8 groves), and KSNX (spiral with soft flute insert). Apart from the nozzle types, the yarn production conditions and machine parameters were kept the same. All production activities were realized under the same mill conditions. For yarn hairiness, yarn evenness and yarn imperfections, an Uster Tester 4SX and for yarn tenacity an Uster Tensorapid 3 tester were used. The test results were analysed using the one way- ANOVA statistical method of Design Expert 6.0.1. In one of the evaluations, it is clearly seen that the nozzle type mostly affects yarn quality and yarn tenacity.
Zbadano wpływ rodzaju dyszy, jako jednego z najważniejszych elementów systemu przędzenia rotorowego na jakość przędzy. Do produkcji przędz 20 tex użyto 100% bawełny Urfa Region. Badania eksperymentalne wykonano na dziesięciu zespołach przędących przędzarki Rieter R1, stosując pięć różnych rodzajów dysz ceramicznych: K4KK, K4KS, K6KF, K8KK oraz KSNX. Warunki wytwarzania przędzy i parametry przędzarki pozostały bez zmian. Uster Tester 4SX zastosowano w celu zbadania włochatości, równomierności grubości i wad przędzy, natomiast Uster Tensorapid 3 zastosowano do oceny wytrzymałości na rozciąganie przędzy. Otrzymane wyniki analizowano stosując jednoczynnikowy test ANOVA. Stwierdzono, że rodzaj dyszy głównie wpływa na jakość przędzy i jej wytrzymałość na rozciąganie.
Źródło:
Fibres & Textiles in Eastern Europe; 2013, 2 (98); 38-42
1230-3666
2300-7354
Pojawia się w:
Fibres & Textiles in Eastern Europe
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Investigation on Regenerated Cellulosic Knitted Fabric Performance by Using Silicone Softeners with Different Particle Sizes
Badanie jakości dzianin wykonanych z różnych włókien zregenerowanej celulozy przy zastosowaniu zmiekczaczy o róznych rozmiarach cząstek
Autorzy:
Sarioğlu, E.
Çelik, N.
Powiązania:
https://bibliotekanauki.pl/articles/231988.pdf
Data publikacji:
2015
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Biopolimerów i Włókien Chemicznych
Tematy:
regenerated fibers
silicone softeners
pilling resistance
rubbing fastness
colour analysis
regenerowane włókna
odporność na pilling
silikonowe zmiękczacze
odporność na tarcie
analiza koloru
Opis:
Silicone softeners make fabric not only softer, brighterd slippery but also more elastic in order to produce desirable handle. In this paper, the affect of silicone softeners on some mechanical and functional properties of knitted regenerated (viscose, modal, Viloft®, micromodal, lyocell and bamboo) fabrics were assessed. For this purpose, commercially used silicone softeners with three different particle sizes (macro, semi-macro, micro) were applied on these fabrics by a continuous methodin identical conditions. The impact of using different softeners on the weight, thickness, pilling resistance, wet and dry rubbing fastness, total colour change and air permeability of these fabrics were investigated. Results revealed that the highest colour efficiency is obtained from lyocell fabrics. Silicone softener application increased the pilling performance of regenerated cellulose fabrics but had no affect on the wet and dry rubbing color fastness. It was found that the application of softeners has a significant affect on air permeability with respect to untreated fabrics.
Zmiękczacze silikonowe powodują, że dzianiny są nie tylko delikatniejsze, jaśniejsze, bardziej śliskie ale również bardziej elastyczne umożliwiając uzyskanie odpowiedniego uhwytu. W pracy zbadano wpływ zmiękczaczy silikonowych na niektóre właściwości mechaniczne i funkcjonalne dzianin produkowanych z regenerowanych włókien celulozowych (wiskozowych, modalnych, ViloftR, mikromodalnych, lyocell i bambusowych). W tym celu komercyjnie dostępne silikonowe zmiękczacze o trzech rożnych wielkościach cząstek (makro, semi-makro, mikro) były zastosowane stosując ciągłą metodę o warunkach identycznych dla wszystkich przypadków. Badano wpływ na masę, grubość, odporność na pilling, odporność na tarcie na sucho i mokro, zmianę koloru, przepuszczalność powietrza. Zastosowanie zmiękczaczy silikonowych zwiększyło odporność na pilling dzianin wykonanych Eze zregenerowanej celulozy ale nie miało wpływu na odporność na zmianę koloru przy tarciu na mokro i na sucho. Stwierdzono, że zastosowanie zmiękczaczy ma wyraźny wpływ na przepuszczalność powietrza.
Źródło:
Fibres & Textiles in Eastern Europe; 2015, 5 (113); 71-77
1230-3666
2300-7354
Pojawia się w:
Fibres & Textiles in Eastern Europe
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
SEM and X-Ray Diffraction Studies on Microstructures in Cu-26.04%Zn-4.01%Al Alloy
Autorzy:
Aldirmaz, E.
Celik, H.
Aksoy, I.
Powiązania:
https://bibliotekanauki.pl/articles/1399514.pdf
Data publikacji:
2013-07
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
61.66.Dk
07.85.Nc
61.05.cp
68.37.Hk
81.10.Aj
Opis:
Due to fact that Cu-based alloys are very sensitive to the thermal treatments, in scanning electron microscopy and X-ray diffraction observations, according to the different quenching techniques Cu-26.04%Zn-4.01%Al alloys can display different product phases such as martensite and precipitation. Rapidly cooling sample was formed as M18R structure from the ordered $DO_3$ phase and in the monoclinic case, β=89.1° determined for sample. It was seen that a α-precipitation (fcc) phase in the matrix is slowly cooling.
Źródło:
Acta Physica Polonica A; 2013, 124, 1; 87-89
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Crystal structure and EPR investigation of pyrazinamide containing copper (II) 2-nitrobenzoate single crystal
Autorzy:
Çelik, Y.
Bozkurt, E.
Karabulut, B.
Dege, N.
Powiązania:
https://bibliotekanauki.pl/articles/1070369.pdf
Data publikacji:
2016-07
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
61.05.cp
75.10.Dg
76.30.-v
78.30.-j
Opis:
The crystal structure and paramagnetism in the pyrazinamide containing copper(II) 2-nitrobenzoate single crystal were investigated using X-ray diffraction, Fourier-transform infrared spectroscopy, and electron paramagnetic resonance techniques. X-ray diffraction analysis shows that the complex crystallizes in monoclinic system having two molecules in the unit cell. After using curve fitting method to the electron paramagnetic resonance spectra, anisotropic g and hyperfine A tensors were obtained. The local symmetry, spin Hamiltonian parameters, and molecular bonding coefficients of the paramagnetic Cu²⁺ ion were determined. Perturbation approach was applied to the spin Hamiltonian to calculate the g and A values.
Źródło:
Acta Physica Polonica A; 2016, 130, 1; 163-166
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
www-Based Boolean Function Minimization
Autorzy:
Tomaszewski, S. P.
Celik, I. U.
Antoniou, G. E.
Powiązania:
https://bibliotekanauki.pl/articles/908086.pdf
Data publikacji:
2003
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
informatyka
digital logic
logic design
Boolean function
Boolean minimization
Quine-McCluskey metod
Opis:
In this paper a Boolean minimization algorithm is considered and implemented as an applet in Java. The application is based on the Quine-McCluskey simplification technique with some modifications. The given application can be accessed on line since it is posted on the World Wide Web (WWW), with up to four variables, at the URL http://www.csam.montclair.edu/~antoniou/bs. After extensive testing, the performance of the algorithm has been found to be excellent. The proposed application is a useful aid for students and professors in the fields of electrical and computer engineering and computer science as well as a valuable tool for digital designers.
Źródło:
International Journal of Applied Mathematics and Computer Science; 2003, 13, 4; 577-583
1641-876X
2083-8492
Pojawia się w:
International Journal of Applied Mathematics and Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of particle shape properties on selective separation of chromite from serpentine by flotation
Autorzy:
Guven, Onur
Serdengecti, M. Tayhan
Tunc, Berivan
Ozdemir, Orhan
Karaagaclioglu, Ibrahim E.
Çelik, Mehmet S.
Powiązania:
https://bibliotekanauki.pl/articles/1845205.pdf
Data publikacji:
2020
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
chromite
serpentine
morphology
flotation
mineral mixtures
Opis:
Although many studies have been conducted on the morphological variations and its effects on flotation recoveries of a single mineral system, a systematic study for the flotation behavior of mixtures of minerals has not dwelled much. In this study, th flotation behavior of chromite and serpentine minerals was investigated to distinguish and isolate the contribution of morphology in single and binary systems. For this purpose, the shape analyses for the minerals ground as single and mixture were performed, and their flotation behaviors determined with the micro-flotation experiments. Additionally, the zeta potential measurements were carried out in the presence of sodium oleate as a collector. The shape analysis of the ground samples showed that while the roundness values of chromite and serpentine (gangue) minerals as single were quite different, the particle shape of chromite favored serpentine in the mixture system which in turn suggested that the mineral with the high hardness value dominates the shape characteristics in binary grinding conditions. Accordingly, while the flotation characteristics of chromite in the mixture followed the same trend with the flotation of a single chromite system as a function of particle shape, almost a reverse trend was obtained for the shape and flotation of serpentine in the mixture compared to a single serpentine system. Thus, at roundness values of chromite particles from 0.797 to 0.732, the flotation recoveries of chromite in the mixture increased from 51.0% to 75.4%. On the other hand, likewise chromite, the flotation recoveries of serpentine increased from 20.0% to 37.3% proportional to the roundness range of 0.757 and 0.709. These findings in turn showed that the grinding conditions dictate the soft component to be monitored by the harder and denser component which dominates the angularity and floatability of the mixture.
Źródło:
Physicochemical Problems of Mineral Processing; 2020, 56, 5; 818-828
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Optimum separation route for semi bituminous coal using semi-pilot scale pneumatic stratification jig
Autorzy:
Boylu, F.
Cetinel, T.
Guven, O.
Karakas, F.
Cinku, K.
Karaagaclioglu, I. E.
Celik, M. S.
Powiązania:
https://bibliotekanauki.pl/articles/109366.pdf
Data publikacji:
2015
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
semibituminous coal
dry coal cleaning
Allair jig
optimization
Opis:
Nowadays, dry beneficiation technologies with an air dense medium fluidized bed come into prominence in the field of coal preparation. In this study, the optimum conditions for different operational parameters such as discharge stargate rate, pulsation frequency, and superficial air velocity were investigated on separation of semi bituminous coal from Soma (Imbat) region using a semi pilot scale Allair jig unit. The experimental studies were carried out with two coal size fractions of -15+4 and -4+1 mm by applying rougher and scavenging stages. After the optimization of each parameter, the results for the rougher stages indicated that clean coal products could be obtained with 11.80% and 16.74% ash contents for -15+4 mm and -4+1 mm size ranges, respectively. In addition, discardable tailings with 65.44% and 60.95 % ash contents could be obtained as the result for the scavenging stages. Finally, the combination of these results for -15+1 mm size exhibited that 59.80% of the feed material with 37.70% ash content can be upgraded to clean coal products with low ash content as 19.80% while the remaining part was discarded as tailings with 68.60% ash content. These values suggested that optimizing the operational parameters of unit brings better results which are applicable in industrial application of dry processes compared to wet processes.
Źródło:
Physicochemical Problems of Mineral Processing; 2015, 51, 2; 559-573
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Urine iodine excretion in patients with papillary thyroid cancer evaluation of the relationship with the presence of BRAF mutation
Autorzy:
Celik, M.
Guldiken, S.
Ayturk, S.
Yilmaz Bulbul, B.
Kucukarda, A.
Can, N.
Tastekin, E.
Sezer, A.
Sut, N.
Tugrul, A.
Gurkan, H.
Tozkir, H.
Demirkan, B.
Powiązania:
https://bibliotekanauki.pl/articles/1192247.pdf
Data publikacji:
2020
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
Tematy:
papillary thyroid cancer
BRAF mutation
urine iodine excretion
Opis:
Iodine is an essential element for the production of thyroid hormones. In recent years, it has been suggested that excessive consumption of iodine may play a role in the pathogenesis of papillary thyroid cancer (PTC). In addition, studies have suggested that high iodine consumption is an important risk factor for the formation of a BRAF mutation in the thyroid gland. A prospectively designed study included 132 cases scheduled for thyroidectomy for various reasons. Urine iodine levels of all patients were examined before the operation. The iodine excretion levels of the patients were grouped according to the median urinary iodine concentration determined in community screenings (those with <100 µg L-1 low iodine excretion, those with 100-199 µg L-1 normal iodine excretion, those with 200-299 µg L-1 high iodine excretion). Patients were divided into 3 groups according to the post-operative pathology results. As a result of thyroid histopathology, benign (n: 44), PTC (n: 88) (BRAF (+): 44 and BRAF (-): 44) cases were included in the study. BRAF mutations in patients diagnosed with PTC were evaluated using the “Real Time PCR Melting Curve Analyzer” method. The relationship between urinary iodine excretion levels and clinical, histopathological and BRAF positivity was examined. In our study, no difference was found in urinary iodine excretion between patients with and without PTC. Hashimoto’s thyroiditis was observed more frequently in patients with PTC (p=0.023). In addition, Hashimoto’s thyroiditis was statistically more frequently detected in the BRAF (-) group compared to the BRAF (+) and control group (p=0.034). Despite studies suggesting that high iodine consumption is important in PTC pathogenesis, we did not find a relationship between the mutation and iodine consumption, which plays an important role in the development of PTC.
Źródło:
Journal of Elementology; 2020, 25, 3; 1019-1028
1644-2296
Pojawia się w:
Journal of Elementology
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-15 z 15

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