Wszystkie pola: phospholipid modification - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Enzymatyczne i chemiczne modyfikacje fosfolipidów
Enzymatic and chemical modifications of phospholipids
Autorzy:: Chojnacka, Anna
Niezgoda, Natalia
Powiązania:: https://bibliotekanauki.pl/articles/27310043.pdf
Data publikacji:: 2023
Wydawca:: Polskie Towarzystwo Chemiczne
Tematy:: fosfolipidy strukturyzowane
koniugaty fosfolipidowe
bioaktywne kwasy tłuszczowe
modyfikacje fosfolipidów
sprzężony kwas linolowy
dehydroepiandrosteron
niesteroidowe leki przeciwzapalne
lipaza
fosfolipaza
structured phospholipids
phospholipid conjugates
bioactive fatty acids
phospholipid modification
dehydroepiandrosterone
NSAIDs
lipase
phospholipase
Opis:: At the moment, phospholipids are among the most interesting molecules. The possibilities of chemical and enzymatic modifications, while maintaining their integrity and unique nature, also contribute to these compounds' great interest. This review paper concerns the preparation of new phospholipid conjugates containing fragments of biologically active compounds not found naturally in phospholipids, and phospholipids enriched with specific fatty acids with health-promoting properties (structured phospholipids). Chemical methods for the synthesis of phospholipids containing conjugated linolenic acid (CLA), dehydroepiandrosterone (DHEA) or selected non-steroidal anti-inflammatory drugs (NSAIDs) at the sn-1 and/or sn-2 position have been described. In addition, the evaluation of the antiproliferative activity of the obtained conjugates against selected cancer cell lines was also described. Enzymatic methods of modifying natural phospholipids leading to their enrichment with bioactive polyunsaturated fatty acids and conjugated acids have also been described.
Źródło:: Wiadomości Chemiczne; 2023, 77, 5-6; 449--477
0043-5104
2300-0295
Pojawia się w:: Wiadomości Chemiczne
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 2.

Tytuł:: Effect of phospholipid and (phospho)lipase modification on interfacial properties of oil/water emulsion
Autorzy:: Wiącek, Agnieszka Ewa
Powiązania:: https://bibliotekanauki.pl/articles/763941.pdf
Data publikacji:: 2015
Wydawca:: Uniwersytet Marii Curie-Skłodowskiej. Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
Tematy:: dynamic light scattering
phospholipid
phospholipase
zeta potential
effective diameter
Opis:: This review paper focused on the effect of typical phosphorlipid (or lecithin) and enzyme modification on electrokinetic parameters of oil/water emulsion. Physicochemical properties of the systems were investigated taking into account the effective diameter of the droplets as well as the zeta potentials using the dynamic light scattering technique. The effect of phospholipid and phospholipase modification on interfacial properties of o/w emulsion was examined as a function of temperature, pH and ionic strength (effect of Na+ or Ca2+ ions which occur in the physiological fluids). The particular role of Ca2+ ions in the dispersions with zwitterionic phospholipids (the main components of biological membrane) was confirmed.The phospholipids dipalmitoylphosphatidylcholine, DPPC or dioleoylphosphatidylcholine, DOPC having the same headgroup bound to the apolar tail composed of two saturated or unsaturated chains were used as stabilizing agents. The effective diameters do not always correlate with the zeta potentials. A possible reason for such behaviour might a mechanism different from the electrostatic stabilization. Phospholipids and their mixtures (e.g. lecithin) may undergo spontaneous aggregation in aqueous solution and selforganize into liposomes, which possess different sizes and surface affinities. These unique behaviours of phospholipid dispersion can be controlled using the investigated parameters. These findings are expected to increase in importance as phospholipid systems see more use in self-assembly applications.The other aim of the paper was the comparison of the enzyme phospholipase influence on lipid hydrolysis in the o/w emulsion environment. The work is the study which presents the twofold effect of ethanol dipoles on phosholipid hydrolysis. It is believed that the enzyme effect on the phospholipid aggregation behaviour at the oil-water interface will be helpful for understanding differentbiological phenomena.
Źródło:: Annales Universitatis Mariae Curie-Skłodowska, sectio AA – Chemia; 2015, 70, 1
2083-358X
Pojawia się w:: Annales Universitatis Mariae Curie-Skłodowska, sectio AA – Chemia
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Informacja

Wyszukujesz frazę "phospholipid modification" wg kryterium: Wszystkie pola

Źródło danych

Dostawca treści

Kolekcja

Rok wydania

Wydawca

Temat

Autor

Typ dokumentu

Język