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Tytuł:
Motor assessment in Parkinson`s disease
Autorzy:
Opara, Józef A.
Małecki, Andrzej
Małecka, Elżbieta
Socha, Teresa
Powiązania:
https://bibliotekanauki.pl/articles/991125.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
parkinson`s disease
pd
balance
gait
posture
posturometry
Opis:
Parkinson’s disease (PD) is one of most disabling disorders of the central nervous system. The motor symptoms of Parkinson’s disease: shaking, rigidity, slowness of movement, postural instability and difficulty with walking and gait, are difficult to measure. When disease symptoms become more pronounced, the patient experiences difficulties with hand function and walking, and is prone to falls. Baseline motor impairment and cognitive impairment are probable predictors of more rapid motor decline and disability. An additional difficulty is the variability of the symptoms caused by adverse effects of drugs, especially levodopa. Motor assessment of Parkinson`s Disease can be divided into clinimetrics, assessment of balance and posture, arm and hand function, and gait/walking. These are many clinimetric scales used in Parkinson`s Disease, the most popular being the Hoehn and Yahr stages of progression of the disease and Unified Parkinson’s Disease Rating Scale. Balance and posture can be assessed by clinimetric scales like the Berg BS, Tinetti, Brunel BA, and Timed Up and Go Test, or measured by posturometric platforms. Among skill tests, the best known are: the Purdue Pegboard Test, Nine-Hole Peg Test, Jebsen and Taylor test, Pig- Tail Test, Frenchay Arm Test, Action Research Arm Test, Wolf FMT and Finger-Tapping Test. Among motricity scales, the most popular are: the Fugl-Meyer Motor Assessment Scale and Södring Motor Evaluation. Gait and walking can also be assessed quantitatively and qualitatively. Recently, the most popular is three-dimensional analysis of movement. This review article presents the current possibilities of motor assessment in Parkinson`s disease.
Źródło:
Annals of Agricultural and Environmental Medicine; 2017, 24, 3
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Treatment of Parkinson’s disease psychosis
Autorzy:
Black, Kevin J.
Powiązania:
https://bibliotekanauki.pl/articles/1033578.pdf
Data publikacji:
2017
Wydawca:
Zakład Opieki Zdrowotnej Ośrodek Umea Shinoda-Kuracejo
Tematy:
Antipsychotic Agents
Delirium
Delusions/therapy
Hallucinations/therapy
Parkinsonian Disorders
pimavanserin
Opis:
Early in the course of Parkinson disease (PD), treatment usually goes well. However, after five to ten years, things start to change as treatment requires higher doses of medications and side effects become more problematic. One of the most difficult problems is the development of hallucinations or delusions. Throughout the 20th century, treatment options were unproven and unsatisfactory, but the past 20 years have brought important changes. Two medications that are well tolerated in PD have now proved efficacious in randomized, controlled trials, and others are in development. Here I summarize this history briefly and provide a general plan for treating the patient with PD complicated by psychotic symptoms.
Źródło:
Medicina Internacia Revuo; 2017, 28, 109; 266-271
0465-5435
Pojawia się w:
Medicina Internacia Revuo
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Postural stability in Parkinson’s disease patients
Autorzy:
Wilczyński, J.
Pedrycz, A.
Zieliński, E.
Ambroży, T.
Mucha, D.
Powiązania:
https://bibliotekanauki.pl/articles/306998.pdf
Data publikacji:
2017
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
stabilność posturalna
choroba Parkinsona
test stabilności
postural stability
Parkinson's disease
Postural Stability Test
Opis:
Purpose: The aim of the study was to analyze postural stability in Parkinson's disease patients. A total of 32 subjects were tested, including 26 (81.25%) women and 6 (18.75%) men. These were patients with advanced, idiopathic Parkinson’s disease. The disease duration was over 5 years. Methods: The study was conducted in the Posturology Laboratory at the Department of Medicine and Health Sciences, Jan Kochanowski University in Kielce (Poland). The Biodex Balance System was used for evaluation of postural stability. Postural Stability Testing was performed with both feet positioned on a stable surface with the eyes open. Results: The Overall Stability Index in the whole group was 0.5°. The higher Overall Stability Index in women is indicative of slightly worse postural stability compared to men, although in both groups, it was within norms (Z = 2.0545, p = 0.0399). Anterior-Posterior Overall Stability Index (A/P) was an average of 0.35°. The Medial-Lateral Overall Stability Index (M/L) was an average of 0.27°. Both women and men were observed to have higher postural sway in the sagittal plane than the frontal plane. The vast majority of the subjects maintained in Zone A during testing (99.94%), and was slightly bent backwards to the right and in Quadrant IV (61.53%). Conclusions: Regular control of postural stability in Parkinson's disease patients is significant due to the risk of falls.
Źródło:
Acta of Bioengineering and Biomechanics; 2017, 19, 4; 135-141
1509-409X
2450-6303
Pojawia się w:
Acta of Bioengineering and Biomechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
FUNCTIONAL NEUROMARKERS IN PARKINSON’S DISEASE (PD)
Autorzy:
Góral-Półrola, Jolanta
Mirski, Andrzej
Knapik, Henryk
Pąchalska, Maria
Powiązania:
https://bibliotekanauki.pl/articles/2138039.pdf
Data publikacji:
2021-03-20
Wydawca:
Fundacja Edukacji Medycznej, Promocji Zdrowia, Sztuki i Kultury Ars Medica
Tematy:
high rolandic beta
ERPs
HBI methodology
Opis:
New neurotechnologies which help to study not only the structure but also brain work, especially in milliseconds, allow for a more accurate diagnosis of a given disease entity. The aim of our study was to characterize the functional neuromarkers, including a new neuromarker, that is high rolandic beta, in Parkinson’s disease (PD). A 76-year-old male patient, a university professor, a widower, in an intimate relationship with a beloved partner, was tested in the Reintegration and Training Center of the Polish Society of Neuropsychology. Five years earlier (when he was 71 years old), following long-term stress, he had had a transient ischemic attack (TIA). In the following years he experienced two neurological episodes, and was diagnosed, on the basis of MRI findings and clinical symptoms, with vascular (multi-infarct) Parkinsonism. A sudden deterioration in his functioning, including hand tremors at rest, bradykinesia (motor slowdown), asymmetrical gait difficulties, postural instability, and falls typical for PD, as well as MRI finding (the appearance of ‘a swallow tail ’ on the left side, and the lack on the right of the substantia nigra within the midbrain) was the cause of further differential diagnosis. He was assessed using the HBI methodology (Kropotov 2016; Pąchalska, Kaczmarek, Kropotov 2014). EEG was recorded from 19 scalp sites, in resting state conditions, with eyes open and eyes closed, and during the cued GO/NOGO tasks with animal/plants as GO/NOGO stimuli. The electrodes were applied according to the International 10-20 system. The EEG was recorded referentially to linked ears, allowing for a computational re-referencing of the data (remontaging). Event related potentials (ERPs) were used to assess the functional changes manifested by the patient. To compare our patient with healthy controls we used the normative Human Brain Index (HBI), a database obtained through joint research by Swiss, Norwegian, Polish and Russian neuroscientists (Kropotov 2018). This database included behavioral parameters and ERP measures in 6 different neuropsychological tasks for 1000 healthy subjects. What is striking, no signs of cognitive dysfunction was found; however observed were an asymmetrical frontal lobe alpha (a neuromarker of depression) and excessive Rolandic beta (a neuromarker of Parkinson’s disease). We will discuss the results on the basis of recent subject literature findings, including the personal factors that might influenced the process of the diagnosis and treatment of this patient, ones which should be also taken into account in any differential diagnosis. The obtained results show the importance of using HBI methodology in clinical practice. Physicians involved in the diagnosis and treatment of those with progressive ambulatory impairment and an abnormal white matter (WM) signal on neuroimaging, should when formulating any differential diagnosis consider the use of this approach. ------------------------------------------------------------------------------------------------------------------------------------
Źródło:
Acta Neuropsychologica; 2021, 19(2); 147-168
1730-7503
2084-4298
Pojawia się w:
Acta Neuropsychologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Continuous subcutaneous apomorphine monotherapy in Parkinson’s disease
Autorzy:
Papuć, E.
Trzciniecka, O.
Rejdak, K.
Powiązania:
https://bibliotekanauki.pl/articles/2082065.pdf
Data publikacji:
2018
Wydawca:
Instytut Medycyny Wsi
Tematy:
Parkinson’s disease
apomorphine
continuous subcutaneous infusion
monotherapy
apomorphine pump
Opis:
Introduction and objective. Continuous subcutaneous apomorphine (APO) treatment is one of the 3 therapeutic options for advanced Parkinson’s disease (PD), in addition to deep brain stimulation (DBS) and intrajejunal levodopa. Data from previously performed studies show that few PD patients can achieve APO infusion as monotherapy. The current pilot study presents the authors’ experience in achieving APO monotherapy. Materials and method. During the last 2 years, 9 patients with APO were treated in the Department of Neurology of the Medical University of Lublin; each patient was offered a 5-day duration APO treatment as monotherapy. The main indication for the APO therapy was advanced PD with motor fluctuations and the patient’s non-agreement for DBS therapy. Mean age of treated patients – 65.11 years, mean disease duration – 7.67 years, mean Hoehn-Yahr – 2.67, mean L-dopa equivalent before APO treatment – 1751.11 mg, mean daily dose of apomorphine as monotherapy – 106.11 ± 14.09 mg. Results. All treated patients managed to achieve APO monotherapy. A statistically significant reduction was found in the duration of the ‘off’ states in the observed PD patients on APO monotherapy (p<0.05). No significant improvement was observed in the III motor score of the UPDRS on APO treatment, compared to optimized oral therapy used before APO treatment. Conclusions. APO monotherapy can be achieved in advanced PD, and seems to be a good therapeutic option for this group of patients, especially in that it allows a significant reduction in the off-time which significantly simplifies the drug regime. Nevertheless, hospital admission with experienced neurologist supervision is recommended when establishing a PD patient’s APO monotherapy.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 1; 133-137
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Żywienie w chorobie Parkinsona
Nutrition in Parkinson’s disease
Autorzy:
Gorzkowska, Agnieszka
Powiązania:
https://bibliotekanauki.pl/articles/1029770.pdf
Data publikacji:
2017
Wydawca:
Medical Communications
Tematy:
choroba Parkinsona
dieta
leczenie
Opis:
Parkinson’s disease is a chronic neurodegenerative disorder with extensive motor and non-motor symptoms. Several specific dietary components have emerged as being of potential importance in the occurrence and course of Parkinson’s disease. Inappropriate nutrition is likely to aggravate neurodegenerative processes. Conversely, a proper diet can be an element of therapy and a potential neuroprotective factor that slows down the progression of the disease. Even the effectiveness of pharmacological treatment in Parkinson’s disease may be affected by dietary habits. Parkinson’s disease patients have also specific nutritional needs related to non-motor problems resulting from changes occurring in the course of the disease. Adequate nutrition needs also to be considered in the context of barriers posed by the disease in food intake. A proper diet in Parkinson’s disease should ensure the maintenance of normal body weight, meet the demand for proteins, fats, carbohydrates, fibre, vitamins and minerals in accordance with the current standards, aid the effective action of drugs and therapy of the prevalent symptoms, and thus, in the light of current scientific research, facilitate a slower or milder course of the disease. Currently, the Mediterranean diet meets the most expectations in this case. However, it should be emphasized that the nutrition of each Parkinson’s disease patient requires a fully individual approach, taking into consideration the stage and the picture of the disease and comorbidities. A lack of fully effective management concerning dietary pattern is reflected by high rates of malnutrition in this population of patients. The article presents the current views on the dietary problems associated with Parkinson’s disease and the potential for using nutritional guidance to optimise the treatment of Parkinson’s disease patients.
Choroba Parkinsona to przewlekła choroba neurozwyrodnieniowa o bogatej symptomatologii ruchowej i pozaruchowej. Wśród czynników wpływających na ryzyko wystąpienia choroby i na jej przebieg ważne miejsce zajmują składniki codziennej diety. Jest wysoce prawdopodobne, że niewłaściwe żywienie promuje procesy neurodegeneracyjne. Odpowiedni sposób odżywiania to potencjalny element terapii i czynnik neuroprotekcyjny, spowalniający postęp choroby. Pod wpływem diety zmieniać się może skuteczność leczenia farmakologicznego. Pacjenci z chorobą Parkinsona mają specyficzne potrzeby żywieniowe związane z problemami pozaruchowymi, żywienie jest również istotne w kontekście barier w przyjmowaniu pokarmu stwarzanych przez chorobę. Dieta chorego powinna zapewniać utrzymanie prawidłowej masy ciała, zaspokajać zapotrzebowanie na białka, tłuszcze, węglowodany, błonnik, witaminy i składniki mineralne zgodnie z aktualnymi normami, wspomagać działanie leków i terapię dominujących objawów, a w świetle badań naukowych – wiązać się z wolniejszym lub łagodniejszym przebiegiem choroby. Najwięcej oczekiwań spełnia obecnie dieta śródziemnomorska, należy jednak podkreślić, że żywienie każdej osoby z chorobą Parkinsona wymaga indywidualnego podejścia: uwzględnienia etapu i obrazu choroby oraz schorzeń współistniejących. Brak w pełni skutecznego postępowania w tym względzie przejawia się w wysokich wskaźnikach niedożywienia w analizowanej populacji chorych. W artykule przedstawiono aktualne spojrzenie na problemy związane z żywieniem oraz możliwości wykorzystania zaleceń dietetycznych w optymalizacji prowadzenia pacjenta z chorobą Parkinsona.
Źródło:
Aktualności Neurologiczne; 2017, 17, 4; 199-207
1641-9227
2451-0696
Pojawia się w:
Aktualności Neurologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hiperseksualność w chorobie Parkinsona
Hypersexuality in Parkinson’s disease
Autorzy:
Kopka, Marcin
Powiązania:
https://bibliotekanauki.pl/articles/1029900.pdf
Data publikacji:
2017
Wydawca:
Medical Communications
Tematy:
choroba Parkinsona
czynniki ryzyka
hiperseksualność
leczenie
Opis:
Hypersexuality is defined as a continuous, devastating and persistent need associated with human sexual life. It belongs to a group of complex behavioural disorders referred to as impulse control disorders. It is estimated that the incidence of hypersexuality in people with Parkinson’s disease ranges from 2% to 4%. In patients treated for Parkinson’s disease, hypersexuality is diagnosed more often than in the general population. The pathophysiology of hypersexuality in patients with Parkinson’s disease is not fully understood. It is suggested that the treatment of the underlying disease plays a significant role. In the literature, the majority of reports of hypersexuality cases have been linked to treatment with dopamine agonists, however, cases treated with levodopa, monoamine oxidase inhibitors or deep brain stimulation have also been reported. The risk factors of hypersexuality in patients with Parkinson’s disease include male gender, early onset of the disease and treatment with dopamine agonists. Little is known about the optimal management strategies for Parkinson’s disease patients with hypersexuality. Two long-term follow-up studies, although conducted in small groups, have indicated that discontinuation of dopamine agonists leads to full remission or clinically significant reduction of the symptoms of hypersexuality. Further studies are needed to determine how to successfully treat hypersexuality in patients with Parkinson’s disease.
Hiperseksualność definiowana jest jako ciągła, wyniszczająca i uporczywa potrzeba związana z życiem seksualnym człowieka. Należy do grupy złożonych zaburzeń zachowania określanych terminem „zaburzenia kontroli impulsów”. Szacuje się, że częstość występowania hiperseksualności wśród osób z chorobą Parkinsona wynosi od 2 do 4%. U pacjentów leczonych z powodu tej choroby hiperseksualność rozpoznawana jest częściej niż w populacji ogólnej. Patofizjologia hiperseksualności u osób z chorobą Parkinsona nie została jeszcze do końca poznana. Sugeruje się, że istotną rolę odgrywa leczenie stosowane w tym schorzeniu. W większości doniesień naukowych łączono hiperseksualność z leczeniem za pomocą agonistów dopaminy, chociaż opisywano również przypadki hiperseksualności po lewodopie, inhibitorach monoaminooksydazy B czy głębokiej stymulacji mózgu. Do czynników ryzyka zwiększających ryzyko hiperseksualności u osób z chorobą Parkinsona zalicza się płeć męską, wczesny początek choroby oraz stosowanie agonistów dopaminy. Niewiele wiadomo na temat postępowania u pacjentów z chorobą Parkinsona i objawami hiperseksualności. Wyniki dwóch badań follow-up z udziałem małych grup chorych wskazują, że przerwanie leczenia agonistami dopaminy może prowadzić do całkowitego ustąpienia lub znacznej redukcji objawów hiperseksualności. Konieczne są dalsze badania, które pozwolą na opracowanie skutecznych metod terapii hiperseksualności u osób z chorobą Parkinsona.
Źródło:
Aktualności Neurologiczne; 2017, 17, 3; 158-161
1641-9227
2451-0696
Pojawia się w:
Aktualności Neurologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Kinezyterapia w chorobie Parkinsona
Kinesitherapy in Parkinson’s disease
Autorzy:
Kozak‑Putowska, D.
Ilzecka, J.
Piskorz, J.
Wojcik, G.
Nalepa, D.
Powiązania:
https://bibliotekanauki.pl/articles/943522.pdf
Data publikacji:
2015
Wydawca:
Instytut Medycyny Wsi
Opis:
Wprowadzenie. Choroba Parkinsona jest nieuleczalną, zwyrodnieniową chorobą układu nerwowego, prowadzącą do postępującej niesprawności, uzależnienia od pomocy innych oraz obniżonej jakości życia. Cel pracy. Celem niniejszej pracy jest przedstawienie najważniejszych kwestii dotyczących kinezyterapii chorych na chorobę Parkinsona na podstawie piśmiennictwa. Skrócony opis stanu wiedzy. Zastosowanie kinezyterapii jest nieodłącznym elementem leczenia i odgrywa bardzo ważną rolę w procesie usprawniania i przystosowania pacjenta do życia z chorobą. Ćwiczenia nie tylko mają istotny wpływ na występujące objawy w przebiegu choroby, ale też na ogólny stan zdrowia. Choroba przebiega u każdego pacjenta w odmienny sposób, dlatego ważny jest indywidualny dobór terapii, w zależności od występujących objawów ruchowych, jak i pozaruchowych, a także ogólnego stanu zdrowia pacjenta. Ćwiczenia zalecane u chorych na chorobę Parkinsona to ćwiczenia oddechowe, chodu, ćwiczenia wzmacniające, równoważne, koordynacyjne, rozciągające, relaksacyjne, muzykoterapia, taniec oraz gry i zabawy ruchowe. Regularne wykonywanie ćwiczeń, zaangażowanie pacjenta oraz realizowanie programu ćwiczeń, również w warunkach domowych, jest warunkiem efektywności kinezyterapii. Podsumowanie. Kinezyterapia odgrywa bardzo ważną rolę w usprawnianiu pacjenta z chorobą Parkinsona, zapobieganiu trwałej niepełnosprawności oraz utrzymaniu jak najdłuższej samodzielności i dobrej jakości życia.
Introduction. Parkinson’s disease is an incurable, degenerative disease of the nervous system, leading to progressive disability, loss of independence and reduced quality of life. Objective. The aim of this study is presentation of the most important issues concerning kinesitherapy in Parkinson’s disease. Short description of state of knowledge. Kinesitherapy is an inseparable part of the treatment and plays a very important role in the process of increasing efficiency and adaptation of the patient to live with the disease. Exercises not only have a significant impact on the common symptoms in the course of the disease, but also on the general state of health. The course of the disease is different in each patient; therefore, an individual selection of therapy is important. It depends on motor and non-motor symptoms, and the general state of health. Exercises recommended in patients with Parkinson’s disease are: breathing exercises, gait learning, strengthening, coordination, relaxation exercises, music therapy, dancing and movement games. Regular exercises, patient’s active involvement and the implementation of an exercise programme in the home environment is a prerequisite for the effectiveness of kinesitherapy. Summary. Kinesitherapy plays an important role in the process of increasing the efficiency of a patient, preventing disability and maintaining independence and good quality of life as long as possible.
Źródło:
Medycyna Ogólna i Nauki o Zdrowiu; 2015, 21(50), 1
2083-4543
Pojawia się w:
Medycyna Ogólna i Nauki o Zdrowiu
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Diagnosing Parkinson’s disease using the classification of speech signals
Autorzy:
Froelich, W.
Wróbel, K.
Porwik, P.
Powiązania:
https://bibliotekanauki.pl/articles/333984.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Śląski. Wydział Informatyki i Nauki o Materiałach. Instytut Informatyki. Zakład Systemów Komputerowych
Tematy:
Parkinson's disease
medical diagnosis
data classification
choroba Parkinsona
diagnostyka medyczna
klasyfikacja danych
Opis:
This paper addressees the problem of an early diagnosis of Parkinson’s disease by the classification of characteristic features of person’s voice. A new, two-step classification approach is proposed. In the first step, the voice samples are classified using standard state-of-the-art classifiers. In the second step, the classified samples are assigned to patients and the final classification process based on majority criterion is performed. The advantage of using our new approach is the resulting, reliable patientoriented medical diagnose. The proposed two-step method of classification allows also to deal with the variable number of voice samples gathered for every patient. Preliminary experiments revealed quite satisfactory classification accuracy obtained during the performed leave-one-out cross validation.
Źródło:
Journal of Medical Informatics & Technologies; 2014, 23; 187-193
1642-6037
Pojawia się w:
Journal of Medical Informatics & Technologies
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Choroba Parkinsona – postępowanie pielęgnacyjno-rehabilitacyjne wobec chorego na chorobę Parkinsona
Parkinson’s disease – nursing and rehabilitation proceedings against the patient with Parkinson’s disease
Autorzy:
Wrońska, Elżbieta
Krawczyk, Izabella
Wnuk, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/470236.pdf
Data publikacji:
2012
Wydawca:
Europejskie Centrum Kształcenia Podyplomowego
Tematy:
choroba Parkinsona
zespół objawów
postępowanie leczniczo-pielęgnacyjne
problemy pielęgnacyjne
Parkinson’s disease
syndrome
medical and nursing procedures
care problems
Opis:
Choroba Parkinsona jest samoistną, powoli postępującą zwyrodnieniową chorobą układu nerwowego. Dotyczy głównie osób starszych, a średni wiek zachorowalności wynosi 58 lat. Częściej chorują mężczyźni niż kobiety i dotyczy coraz większej liczby osób. Według WHO, na świecie jest 5 mln chorych na tę chorobę. Do głównych objawów zaliczamy: drżenie spoczynkowe, spowolnienie ruchowe oraz sztywność mięśni. Mechanizm jej powstawanie nie został wyjaśniony, ale proces zwyrodnieniowy dotyczy jąder podkorowych, a zwłaszcza istoty czarnej i dochodzi do zachwiania układu dopaminergicznego, a w konsekwencji do destabilizacji w innych układach neuroprzekaźnikowych. Postępowanie terapeutyczne w chorobie Parkinsona jest bardzo złożone i powinno uwzględniać nie tylko farmakoterapie, ale także inne rodzaje oddziaływań na chorego i chorobę, takie jak: rehabilitacje, odpowiedni tryb życia oraz właściwą dietę, a także edukację i wsparcie zarówno chorych, jak i ich rodzin. Celem pracy jest przedstawienie problemu zdrowotnego chorych na chorobę Parkinsona oraz postępowanie leczniczo-pielęgnacyjne wobec chorego na chorobę Parkinsona.
Idiopathic Parkinson’s disease is a slowly progressive degenerative disease of the nervous system. This concerns mainly the elderly, and the average age of incidence is 58 years. There is a higher rate of Parkinson’s disease in men than women and it concerns an increasing number of people. According to WHO, there are five million people suffering from this disease in the world. The main symptoms are following: tremor at rest, slowness of movement and muscle stiffness. The mechanism of its formation has not been elucidated, but the degenerative process concerns the basal ganglia, particularly the substantia nigra and comes to erode the dopaminergic system and consequently to the destabilization of other neurotransmitter systems. Therapeutic treatment for Parkinson’s disease is complex and should include not only pharmacotherapy, but also other types of impacts on patient and disease, such as rehabilitation, appropriate lifestyle and diet as well as education and support to both patients and their families. The aim of this work was to present a health problem in patients with Parkinson’s disease as well as nursing procedures to a patient with Parkinson’s disease.
Źródło:
Współczesne Pielęgniarstwo i Ochrona Zdrowia; 2012, 3; 66-68
2084-4212
Pojawia się w:
Współczesne Pielęgniarstwo i Ochrona Zdrowia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Parkinson’s disease diagnostics using AI and natural language knowledge transfer
Autorzy:
Chronowski, Maurycy
Kłaczyński, Maciej
Dec-Ćwiek, Małgorzata
Porębska, Karolina
Powiązania:
https://bibliotekanauki.pl/articles/27313815.pdf
Data publikacji:
2024
Wydawca:
Polska Akademia Nauk. Polskie Towarzystwo Diagnostyki Technicznej PAN
Tematy:
Parkinson’s disease
digital diagnostics
artificial intelligence
speech processing
Opis:
With global life expectancy rising every year, ageing-associated diseases are becoming an increasingly important problem. Very often, successful treatment relies on early diagnosis. In this work, the issue of Parkinson's disease (PD) diagnostics is tackled. It is particularly important, as there are no certain antemortem methods of diagnosing PD - meaning that the presence of the disease can only be confirmed after the patient's death. In our work, we propose a non-invasive approach for classification of raw speech recordings for PD recognition using deep learning models. The core of the method is an audio classifier using knowledge transfer from a pretrained natural language model, namely wav2vec 2.0. The model was tested on a group of 38 PD patients and 10 healthy persons above the age of 50. A dataset of speech recordings acquired using a smartphone recorder was constructed and the recordings were labelled as PD/non-PD with the severity of the disease additionally rated using Hoehn-Yahr scale. We then benchmarked the classification performance against baseline methods. Additionally, we show an assessment of human-level performance with neurology professionals.
Źródło:
Diagnostyka; 2024, 25, 1; art. no. 2024103
1641-6414
2449-5220
Pojawia się w:
Diagnostyka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zaburzenia autonomiczne w chorobie Parkinsona
Autonomic dysfunctions in Parkinson’s disease
Autorzy:
Fiszer, Urszula
Powiązania:
https://bibliotekanauki.pl/articles/1058758.pdf
Data publikacji:
2009
Wydawca:
Medical Communications
Tematy:
Parkinson’s disease
autonomic disturbances
levodopa
non-motor symptoms
orthostatic hypotension
lewodopa
objawy pozaruchowe
zaburzenia autonomiczne
niedociśnienie ortostatyczne
choroba Parkinsona
Opis:
Idiopathic Parkinson’s disease is a progressive neurological disorder, characterized by the occurrence of various movement and non-motor disturbances (olfactory, neuropsychiatric and autonomic dysfunctions). This paper discusses autonomic disturbances in Parkinson’s disease, which significantly impair patients. Autonomic dysfunctions are present already in early disease stages. They include cardiovascular, urogenital system dysfunctions, gastrointestinal, feeding, thermoregulatory disturbances, and seborrhoea. Autonomic dysfunctions in Parkinson’s disease are related to the function of parasympathetic and sympathetic system. This paper discusses the detailed clinical and neuropathological correlation, which includes scope of the autonomic functions. The research proved that disability of patients with Parkinson’s disease is mainly related to the levodopa non-responding symptoms (neuropsychiatric disturbances, falls, dysphagia, urinary dysfunction and orthostatic hypotension). These disturbances significantly worsen the patient’s life quality, and even disallow an independent functioning. In such cases there is a need to consider administration of drugs with action mechanism different than dopaminergic. There is a need to recognize the levodopa non-responding symptoms in patients with Parkinson’s disease, which may be very disturbing for the patient. A proper diagnosis of patient’s dysfunctions is very important, since sometimes an increasing levodopa treatment may have a negative impact upon patient’s condition. The paper discusses various therapy methods, based mainly upon the recommendations of the European Federation of Neurological Societies (EFNS).
Idiopatyczna choroba Parkinsona jest postępującym neurologicznym schorzeniem charakteryzującym się występowaniem licznych, różnych ruchowych i pozaruchowych zaburzeń (zaburzenia węchu, neuropsychiatryczne oraz układu autonomicznego). Niniejsza praca omawia zaburzenia autonomiczne w chorobie Parkinsona, które w sposób poważny upośledzają chorych. Zaburzenia autonomiczne mogą być obecne już we wczesnych okresach choroby. Obejmują dysfunkcje układu sercowo-naczyniowego, układu moczowo-płciowego, zaburzenia żołądkowo-jelitowe, odżywiania, termoregulacji oraz wydzielanie łoju. Zaburzenia autonomiczne w chorobie Parkinsona związane są z funkcją układu przywspółczulnego i współczulnego. W pracy omówiono dokładną korelację kliniczno-neuropatologiczną zawierającą zakres funkcji autonomicznych. Badania wykazały, że niesprawność osób z chorobą Parkinsona głównie jest związana z objawami niereagującymi na leczenie lewodopą (zaburzenia neuropsychiatryczne, upadki, dysfunkcje połykania i układu moczowego oraz niedociśnienie ortostatyczne). Zaburzenia te znacznie pogarszają jakość życia chorego, a nawet uniemożliwiają mu samodzielne funkcjonowanie. W takich przypadkach istnieje konieczność rozważenia podawania leków o innym mechanizmie działania niż leki dopaminergiczne. Istnieje konieczność rozpoznawania u osób z chorobą Parkinsona objawów niereagujących na leczenie lewodopą, które mogą być bardzo uciążliwe dla chorego. Właściwe rozpoznanie zaburzeń u chorego jest bardzo ważne, gdyż czasami zwiększanie dawki lewodopy może mieć negatywny wpływ na stan pacjenta. W pracy są dyskutowane różne sposoby leczenia, głównie w oparciu o zalecenia Europejskiej Federacji Towarzystw Neurologicznych (EFNS).
Źródło:
Aktualności Neurologiczne; 2009, 9, 3; 159-163
1641-9227
2451-0696
Pojawia się w:
Aktualności Neurologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
QUALITY OF LIFE AMONGST CARE GIVERS FOR PATIENTS WITH PARKINSON’S DISEASE
Autorzy:
Cholewa, Joanna
Rychły, Anna
Rafalska, Beata
Cholewa, Jarosław
Powiązania:
https://bibliotekanauki.pl/articles/449162.pdf
Data publikacji:
2016
Wydawca:
Politechnika Opolska. Wydział Wychowania Fizycznego i Fizjoterapii
Tematy:
Parkinson’s disease
quality of life
caregivers
life satisfaction
Opis:
Parkinson’s disease (PD) is a neurodegenerative disease. Due to a constantly growing rate of incidence and the lowering age of PD patients it is becoming a more serious social problem. The aim of this study is to assess the quality of life amongst care givers for people suffering from Parkinson's disease. The work includes research on the influence of physical rehabilitation of PD patients on the quality of life of their care givers. The research covered care givers (n=50) of PD patients diagnosed with third stage PD according to the Hoehn and Yahr classification. The diagnostics survey with a questionnaire addressed to care givers looking after PD patients was used. The questionnaire was created by the authors of this paper. The survey consisted of two parts, in which the first was to obtain basic information on the present status of the care giver, while the other was to verify life satisfaction level, using Jurczynski's Scale of Life Satisfaction. Statistical analysis showed significant differences in all analyzed statements between groups. Better effects were observed in the group participating in rehabilitation. Care for people suffering from PD affects the quality of life of caregivers. Participation in the process of rehabilitation of patients with PD improves the quality of life of caregivers.
Źródło:
Journal of Physical Education & Health - Social Perspective; 2016, 5, 7; 47-53
2084-7971
Pojawia się w:
Journal of Physical Education & Health - Social Perspective
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of executive processes in working memory deficits in Parkinson’s Disease
Autorzy:
Gruszka, Aleksandra
Bor, Daniel
Barker, Roger R.
Necka, Edward
Owen, Adrian M.
Powiązania:
https://bibliotekanauki.pl/articles/430574.pdf
Data publikacji:
2016-04-01
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Parkinson’s disease
spatial working memory
verbal working memory
frontal lobe
executive function
Opis:
Idiopathic Parkinson’s disease (PD) impairs working memory, but the exact nature of this deficit in terms of the underlying cognitive mechanisms is not well understood. In this study patients with mild clinical symptoms of PD were compared with matched healthy control subjects on a computerized battery of tests designed to assess spatial working memory and verbal working memory. In the spatial working memory task, subjects were required to recall a sequence of four locations. The verbal working memory task was methodologically identical except for the modality of the stimuli used, requiring subjects to orally recall a sequence of six digits. In either case, half of the sequences were structured in a way that allowed ‘chunking’, while others were unstructured. This manipulation was designed to dissociate the strategic component of task performance from the memory-load component. Mild medicated patients with PD were impaired only on the structured versions of the verbal working memory tasks. The analogous deficit in the spatial working memory was less pronounced. These findings are in agreement with the hypothesis that working memory deficits in PD reflect mainly the executive component of the tasks and that the deficits may be at least partly modality-independent.
Źródło:
Polish Psychological Bulletin; 2016, 47, 1; 123-130
0079-2993
Pojawia się w:
Polish Psychological Bulletin
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Humoral response against myelin associated glycoprotein reflects oligodendroglial degeneration in Parkinson’s disease
Autorzy:
Papuc, E.
Wilczynska, B.
Rejdak, K.
Powiązania:
https://bibliotekanauki.pl/articles/51200.pdf
Data publikacji:
2016
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2016, 23, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Comparative analysis of computer typing of healthy people and people with Parkinson’s disease
Autorzy:
Anchimowicz, Anna
Derlatka, Marcin
Powiązania:
https://bibliotekanauki.pl/chapters/2215317.pdf
Data publikacji:
2022
Wydawca:
Politechnika Białostocka. Oficyna Wydawnicza Politechniki Białostockiej
Tematy:
Parkinson’s disease
keyboard typing
statistical analysis
Opis:
Nowadays, methods are being searched in order to detect Parkinson’s disease at an early stage. This would aid faster diagnosis and a more objective assessment of the severity of the condition. This paper focuses on examining whether typing differs between healthy people and people with varying degrees of Parkinson’s disease. The analysis used publicly available data from the physionet.org database [1], which contains results from 227 people over several experimental days. Data from only 108 subjects were used, with a maximum of 3 days of use of the Tappy application by one participant with at least 200 clicks considered. Computer keyboard typing parameters, such as button hold time, latency and flight time were taken into account. Statistical analysis of the data obtained using non-parametric Kruskal-Wallis tests showed that there were no statistically significant differences (α < 0.05) between the study groups (healthy people and people with varying degrees of Parkinson’s disease). However, the reason for this may be the small study group and the lack of consideration of medications taken when matching to groups.
Źródło:
Advances in biomedical engineering; 99-107
9788367185400
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rehabilitacja zamrożeń chodu w przebiegu choroby Parkinsona
Freezing of gait rehabilitation in Parkinson’s disease
Autorzy:
Skalska-Dulińska, Barbara
Witkiewicz, Borys
Ptasznik, Iwona
Powiązania:
https://bibliotekanauki.pl/articles/1053312.pdf
Data publikacji:
2014
Wydawca:
Medical Communications
Tematy:
Parkinson’s disease
cues
freezing of gait
gait disturbance
gait rehabilitation
zaburzenia chodu
zamrożenia
wskazówki
rehabilitacja chodu
choroba Parkinsona
Opis:
Freezing of gait is the episodic gait disturbance common in Parkinson’s disease, often leading to falls and patient’s activity reduction. Physical rehabilitation should be an integral part of the treatment of Parkinson’s disease because of its different course, reaction to pharmacological treatment and progression. Especially in the case of the dominant gait and posture disorders, with stronger bradykinesia and freezing episodes special attention should be paid to gait training and the usage of techniques and equipment which helps the patient to overcome freezing and reduce its severity. Thanks to the early rehabilitation patients longer retain the ability to walk independently. This work aims to present possibilities of using different methods and equipment in the rehabilitation of patient with Parkinson’s disease. Due to the impairment of the functioning mechanism of the generation of internal stimuli the external signals are of particular importance as well as cognitive strategies, among which we can distinguish acoustic stimuli, visual and tactile, on which the widespread method of Frenkel is based on. Not without significance are also external aids such as canes, walkers and crutches recommended for patients with less efficiency.
Zamrożenia chodu to epizodyczne zaburzenia chodu występujące w przebiegu choroby Parkinsona, często prowadzące do upadków i ograniczenia aktywności chorego. Ze względu na zróżnicowany przebieg choroby, odmienną reakcję na leki u każdego pacjenta oraz postępujący charakter schorzenia rehabilitacja ruchowa powinna stanowić integralną część leczenia. Należy zwrócić szczególną uwagę na trening chodu oraz zastosowanie technik umożliwiających choremu przezwyciężenie zamrożeń i zmniejszenie ich nasilenia, zwłaszcza w przypadku postaci choroby z dominującymi zaburzeniami chodu i postawy, cechującej się bardziej nasiloną bradykinezją i epizodami zamrożeń. Odpowiednio wcześnie rozpoczęta rehabilitacja pozwoli pacjentowi dłużej zachować zdolność samodzielnego poruszania się. Poniższa praca ma na celu przedstawienie możliwości wykorzystania różnych metod i sprzętu pomocniczego w rehabilitacji chorych na chorobę Parkinsona. Ze względu na upośledzenie funkcjonowania mechanizmu generowania bodźców wewnętrznych w postępowaniu rehabilitacyjnym szczególne znaczenie odgrywają zewnętrzne sygnały (tzw. wskazówki) oraz strategie poznawcze, wśród których wyróżnić możemy bodźce akustyczne, wzrokowe i dotykowe – bazuje na nich także szeroko rozpowszechniona metoda Frenkla. Nie bez znaczenia są również pomoce zewnętrzne, takie jak laski, chodziki i kule, zalecane pacjentom o mniejszym stopniu sprawności.
Źródło:
Aktualności Neurologiczne; 2014, 14, 2; 140-148
1641-9227
2451-0696
Pojawia się w:
Aktualności Neurologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Depresja w chorobie Parkinsona. Rola farmakoterapii
Depression in Parkinson’s disease. The role of pharmacotherapy
Autorzy:
Wierzbiński, Piotr
Sobów, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1029667.pdf
Data publikacji:
2018
Wydawca:
Medical Communications
Tematy:
agoniści dopaminy
choroba Parkinsona
depresja
lęk
Opis:
Psychiatric symptoms seem to be an immanent part of Parkinson’s disease. Patients may present with psychotic symptoms, cognitive disorders, sleep disturbances (mainly associated with the REM sleep), dementia as well as depression and anxiety. Depression and anxiety are the most common psychiatric disorders, and are observed in nearly a half of patients with Parkinson’s disease. They are caused by both neurochemical and neuroanatomical abnormalities occurring in this disease. This decreases the quality of life and significantly affects patients’ functioning. Moreover, these disorders are frequently not diagnosed correctly. Numerous studies have shown that the most common drugs are those from the group of selective serotonin reuptake inhibitors. However, there is no strong evidence for their high efficacy. Due to the multifactorial mechanism of action, more effective, but also related with more adverse events, are selective norepinephrine reuptake inhibitors and tricyclic antidepressants. Daily practice and various publications reveal that non-ergoline dopamine agonists, such as ropinirole and pramipexole, may constitute an alternative to antidepressants.
Objawy psychiatryczne wydają się immanentną częścią choroby Parkinsona. U pacjentów mogą wystąpić objawy psychotyczne, zaburzenia funkcji poznawczych, zaburzenia snu (związane przede wszystkim ze snem REM), zespół otępienny, objawy zespołu depresyjnego i zaburzenia lękowe. Depresja i lęk są najczęstszymi zaburzeniami psychiatrycznymi, obecnymi u prawie połowy osób z chorobą Parkinsona. U podstaw objawów depresyjnych i lękowych leżą zarówno zmiany neurochemiczne, jak i zmiany neuroanatomiczne występujące w tej chorobie. Obniżają one jakość życia, istotnie wpływają na funkcjonowanie pacjenta, a ich pojawienie się często nie jest właściwie rozpoznawane. Na podstawie licznych badań wiadomo, że najczęściej stosowane są leki z grupy selektywnych inhibitorów wychwytu zwrotnego serotoniny. Brakuje niestety mocnych dowodów na ich dużą skuteczność. Z uwagi na wielomediatorowy mechanizm działania dobrym wyborem – bardziej efektywnym, ale też związanym z większą liczbą działań niepożądanych – mogą być selektywne inhibitory wychwytu zwrotnego noradrenaliny i trójpierścieniowe leki przeciwdepresyjne. Jak wynika z codziennej praktyki i licznych publikacji, alternatywą dla leków przeciwdepresyjnych są nieergolinowi agoniści dopaminy, tacy jak ropinirol czy pramipeksol.
Źródło:
Aktualności Neurologiczne; 2018, 18, 1; 14-20
1641-9227
2451-0696
Pojawia się w:
Aktualności Neurologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Applicability of artificial intelligence in smart healthcare systems for automatic detection of Parkinson’s Disease
Autorzy:
Pallathadka, Harikumar
Padminivalli V., S.J.R.K.
Vasavi, M.
Nancy, P.
Naved, Mohd
Kumar, Harish
Ray, Samrat
Powiązania:
https://bibliotekanauki.pl/articles/38709253.pdf
Data publikacji:
2024
Wydawca:
Instytut Podstawowych Problemów Techniki PAN
Tematy:
Parkinson’s disease
detection
machine learning
relief algorithm
LDA algorithm
SVM-RBF
accuracy
sensitivity
specificity
choroba Parkinsona
wykrywanie
nauczanie maszynowe
algorytm ulgi
Algorytm LDA
dokładność
wrażliwość
specyficzność
Opis:
Parkinson’s disease is associated with memory loss, anxiety, and depression in the brain. Problems such as poor balance and difficulty during walking can be observed in addition to symptoms of impaired posture and rigidity. The field dedicated to making computers capable of learning autonomously, without having to be explicitly programmed, is known as machine learning. An approach to the diagnosis of Parkinson’s disease, which is based on artificial intelligence, is discussed in this article. The input for this system is provided through photographic examples of Parkinson’s disease patient handwriting. Received photos are preprocessed using the relief feature option to begin the process. This is helpful in the process of selecting characteristics for the identification of Parkinson’s disease. After that, the linear discriminant analysis (LDA) algorithm is employed to reduce the dimensions, bringing down the total number of dimensions that are present in the input data. The photos are then classified via radial basis function-support vector machine (SVM-RBF), k-nearest neighbors (KNN), and naive Bayes algorithms, respectively.
Źródło:
Computer Assisted Methods in Engineering and Science; 2024, 31, 2; 175-185
2299-3649
Pojawia się w:
Computer Assisted Methods in Engineering and Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aktywność fizyczna kobiet cierpiących na chorobę Parkinsona
Physical activity of women suffering from Parkinson’s disease
Autorzy:
Cholewa, J.
Kunicki, M.
Rafalska, B.
Powiązania:
https://bibliotekanauki.pl/articles/12781.pdf
Data publikacji:
2016
Wydawca:
Uniwersytet Szczeciński
Opis:
Positive importance of physical activity (PA) in preventing in a wider sense disability in people with Parkinson’s disease (PD) is widely known. PA taken regularly causes maintenance of physical fitness, functional independence and quality of life. The aim of the study was to determine the level of physical activity of women with PD. The study involved 29 women diagnosed with PD, in stage II disease according to Hoehn and Yahr’a scale, and 40 women declaring themselves as healthy. To assess the level of physical activity applied international physical activity questionnaire (IPAQ), in short version. The results obtained in the different groups were compared using analysis of variance. The study showed that the level of physical activity of women with PD varies depending on participation in the rehabilitation process. A statistically significant difference was seen in the level of the PA of women who did not take part in the rehabilitation process compare with healthy subjects, and PA level of women with PD participating in the rehabilitation process was similar to physical activity of healthy people. The conclusion was about needing to take actions to develop a strategy of physical activation for women with the PD.
Źródło:
Aktywność Ruchowa Ludzi w Różnym Wieku; 2016, 4[32]
2299-744X
Pojawia się w:
Aktywność Ruchowa Ludzi w Różnym Wieku
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
INFLUENCE OF PHYSICAL REHABILITATION ON SOCIAL NETWORKS AND QUALITY OF LIFE AMONG PEOPLE WITH PARKINSON’S DISEASE
Autorzy:
Lizoń, Krzysztof
Cholewa, Joanna
Uher, Ivan
Powiązania:
https://bibliotekanauki.pl/articles/449132.pdf
Data publikacji:
2017
Wydawca:
Politechnika Opolska. Wydział Wychowania Fizycznego i Fizjoterapii
Tematy:
Parkinson's disease
social networks
quality of life
rehabilitation
Opis:
Parkinson's Disease (PD) is the second most common neurodegenerative disease. Symptoms relate to the movement and cognitive sphere; they have a negative impact on the quality of life of people suffering from PD. Pharmacotherapy and rehabilitation slow the progression of the disease. The aim of the work was to determine the impact of physical rehabilitation on the level of social relations in the context of the quality of life of people with PD. 47 people with idiopathic PD were involved in the study, all were in the second stage of the disease according to the Hoehn & Yahr scale. The Courage Social Network Index (CSNI) was used to assess social relations. The scales: Quality of Life in Parkinson’s Disease 39 (PDQ-39), Medical Outcomes Study 36-item Short-Form Heath Survey (SF-36) and Parkinson’s Disease Quality of Life Questionnaire (PDQL) were applied in order to evaluate the quality of life of patients The subjects were divided into two groups: research and control. The research group took part in a rehabilitation program two times a week for 45 minutes for three months. The control group did not participate in any form of physical rehabilitation. The results of the research showed a significantly higher level of social bonds as well as quality of life of people with PD participating in physical rehabilitation. At the same time, a higher level of correlation between the level of social bonds and the level of quality of life was found in the research group. Therefore, the positive impact of physical rehabilitation on the level of social bonds and the quality of life of people with PD constituted the conclusion of the work.
Źródło:
Journal of Physical Education & Health - Social Perspective; 2017, 6, 10; 35-42
2084-7971
Pojawia się w:
Journal of Physical Education & Health - Social Perspective
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Assessment of dynamic balance during step initiation in Parkinson’s disease patients and elderly – a validity study
Autorzy:
Juras, Grzegorz
Kamieniarz, Anna
Michalska, Justyna
Słomka, Kajetan
Powiązania:
https://bibliotekanauki.pl/articles/307381.pdf
Data publikacji:
2020
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
choroba Parkinsona
wiek starszy
stabilność postawy
Parkinson’s disease
elderly
postural stability
validity
step initiation
Opis:
The aim of this study was to evaluate the reliability of the novel posturographic procedure and to investigate the relationships between parameters of this procedure and clinical tests. We hypothesised the proposed step initiation procedure to be reliable method of balance and motor disability assessment, especially in patients with neurological deficits. Also, we assumed high significant correlation between parameters of step initiation procedures and clinical tests. Methods: The 35 subjects with idiopathic PD and 35 agedmatched healthy controls participated in this study. The gait initiation was measured using two force platforms. The procedure consisted of three phases: (1) quiet standing on a first platform (2) crossing on the second platform, (3) quiet standing on a second platform. Testing was carried out in four conditions: unperturbed trial, obstacle crossing, step-up and step-down. Results: In the proposed gait initiation procedure, the vCOP, raCOP and rmsCOP showed an excellent reliability (ICC > 0.80). For transit phase, reliability of all variables in all conditions also was excellent (ICC = 0.8–0.9). There were only a few associations between Tinetti scores and posturographic variables in controls, but in PD patients the significant correlations were found between the proposed measures and the UPDRS, Tinetti, FRT, TUG and with the BBS. Conclusions: The proposed gait initiation procedure is reliable and very suitable for the assessment of patients with Parkinson’s disease. It can be used as an objective assessment of the clinical condition and dynamic balance, and help in the designing and programming of the appropriate rehabilitation and treatment.
Źródło:
Acta of Bioengineering and Biomechanics; 2020, 22, 1; 3-10
1509-409X
2450-6303
Pojawia się w:
Acta of Bioengineering and Biomechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Deep learning vs feature engineering in the assessment of voice signals for diagnosis in Parkinson’s disease
Autorzy:
Majda-Zdancewicz, Ewelina
Potulska-Chromik, Anna
Jakubowski, Jacek
Nojszewska, Monika
Kostera-Pruszczyk, Anna
Powiązania:
https://bibliotekanauki.pl/articles/2173626.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
voice processing
Parkinson’s disease
non-linear analysis
convolutional network
przetwarzanie głosu
choroba Parkinsona
analiza nieliniowa
sieci konwolucyjne
Opis:
Voice acoustic analysis can be a valuable and objective tool supporting the diagnosis of many neurodegenerative diseases, especially in times of distant medical examination during the pandemic. The article compares the application of selected signal processing methods and machine learning algorithms for the taxonomy of acquired speech signals representing the vowel a with prolonged phonation in patients with Parkinson’s disease and healthy subjects. The study was conducted using three different feature engineering techniques for the generation of speech signal features as well as the deep learning approach based on the processing of images involving spectrograms of different time and frequency resolutions. The research utilized real recordings acquired in the Department of Neurology at the Medical University of Warsaw, Poland. The discriminatory ability of feature vectors was evaluated using the SVM technique. The spectrograms were processed by the popular AlexNet convolutional neural network adopted to the binary classification task according to the strategy of transfer learning. The results of numerical experiments have shown different efficiencies of the examined approaches; however, the sensitivity of the best test based on the selected features proposed with respect to biological grounds of voice articulation reached the value of 97% with the specificity no worse than 93%. The results could be further slightly improved thanks to the combination of the selected deep learning and feature engineering algorithms in one stacked ensemble model.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2021, 69, 3; art. no. e137347
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Deep learning vs feature engineering in the assessment of voice signals for diagnosis in Parkinson’s disease
Autorzy:
Majda-Zdancewicz, Ewelina
Potulska-Chromik, Anna
Jakubowski, Jacek
Nojszewska, Monika
Kostera-Pruszczyk, Anna
Powiązania:
https://bibliotekanauki.pl/articles/2090742.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
voice processing
Parkinson’s disease
non-linear analysis
convolutional network
przetwarzanie głosu
choroba Parkinsona
analiza nieliniowa
sieci konwolucyjne
Opis:
Voice acoustic analysis can be a valuable and objective tool supporting the diagnosis of many neurodegenerative diseases, especially in times of distant medical examination during the pandemic. The article compares the application of selected signal processing methods and machine learning algorithms for the taxonomy of acquired speech signals representing the vowel a with prolonged phonation in patients with Parkinson’s disease and healthy subjects. The study was conducted using three different feature engineering techniques for the generation of speech signal features as well as the deep learning approach based on the processing of images involving spectrograms of different time and frequency resolutions. The research utilized real recordings acquired in the Department of Neurology at the Medical University of Warsaw, Poland. The discriminatory ability of feature vectors was evaluated using the SVM technique. The spectrograms were processed by the popular AlexNet convolutional neural network adopted to the binary classification task according to the strategy of transfer learning. The results of numerical experiments have shown different efficiencies of the examined approaches; however, the sensitivity of the best test based on the selected features proposed with respect to biological grounds of voice articulation reached the value of 97% with the specificity no worse than 93%. The results could be further slightly improved thanks to the combination of the selected deep learning and feature engineering algorithms in one stacked ensemble model.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2021, 69, 3; e137347, 1--10
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
PSYCHOLOGICAL RESOURCES OF CAREGIVERS OF INDIVIDUALS SUFFERING FROM PARKINSON’S DISEASE, AND THEIR DECLARED FEELING OF BURDEN
Autorzy:
Golińska, Paulina
Bidzan, Mariola
Brown, Jason W
Powiązania:
https://bibliotekanauki.pl/articles/2137783.pdf
Data publikacji:
2017-12-13
Wydawca:
Fundacja Edukacji Medycznej, Promocji Zdrowia, Sztuki i Kultury Ars Medica
Tematy:
caregivers
neurodegenerative diseases
executive function
cognitive dysfunction
sense of coherence
Opis:
The subject literature identifies many predictors of a feeling of burden, yet it often ignores aspects of the psychological and social functioning of caregivers, i.e., resources for efficiently coping with a difficult situation. This study aimed to verify the predictors of a feeling of burden experienced by the caregivers of individuals suffering from Parkinson’s disease, taking into account the cognitive functioning of the patients as well as the psychological resources and social competences of the caregivers themselves. A cross-sectional study was conducted on 20 individuals suffering from Parkinson’s disease and their caregivers. It included a neuropsychiatric examination of the patients, with a special focus on executive functions, as well as an assessment of the psychological and social resources of their caregivers using standard psychometric methods. Self esteem was measured using the SES scale and sense of coherence was measured using SOC-29. The statistical analysis included correlation analysis and multiple hierarchical regression. The duration of the disease as well as cognitive impairments, especially executive dysfunction, are significant predictors of a feeling of burden. A high sense of coherence is associated with a positive assessment of one’s own resources in the context of coping with a difficult situation. The feeling of burden experienced by caregivers of individuals suffering from neurodegenerative disorders is a complex phenomenon, composed of many factors. The predictors discusse in this study point to various individual differences in the psychological resources possessed by caregivers.
Źródło:
Acta Neuropsychologica; 2017, 15(4); 391-405
1730-7503
2084-4298
Pojawia się w:
Acta Neuropsychologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-25 z 86

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