Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Yкраїнський (UK)
Przejdź do strony domowej biblioteki Centralna Biblioteka Wojskowa Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaCentralna Biblioteka Wojskowa

Wyszukujesz frazę "methicillin" wg kryterium: Wszystkie pola

  Lista filtrów
Wyrównaj
Wyświetlanie 1-15 z 20
Tytuł:
Drug resistance profile and detection of genes responsible for methicillin resistance in Staphylococcus aureus isolated from municipal waste
Autorzy:
Wolny-Koładka, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/2203548.pdf
Data publikacji:
2023
Wydawca:
Instytut Technologiczno-Przyrodniczy
Tematy:
drug resistance
mecA gene
methicillin resistance
municipal waste
Staphylococcus aureus
Opis:
Currently, we are facing the ever-increasing phenomenon of bacteria being resistant to antibiotics. It is the consequence of excessive and incorrect use of drugs. The phenomenon is a global problem affecting bacteria both in their hospital population and in the natural environment. Municipal waste is an environment conducive to the development of microorganisms, therefore it contains various groups of bacteria, including drug-resistant staphylococci. The aim of the study was to identify species of bacteria, determine their antibiotic resistance, and assess the occurrence of genes responsible for methicillin resistance in Staphylococcus aureus isolated from mixed municipal waste. Strains were isolated by Koch’s serial dilution method with the use of microbiological media. Species were identified using the MALDI TOF-MS technique, whereas the drug resistance profile was determined by disk diffusion and molecular PCR methods. 250 isolates of S. aureus were collected. The highest resistance found was to cefoxitin, erythromycin and tetracycline. Among the bacteria collected, resistance to 1, 2, 3 or 4 antibiotics at the same time was the most common, with a maximum of 10. Additionally, 45 (18%) MDR (multidrug-resistant) isolates were detected. Methicillin resistance was found by the disk diffusion test in 60 (24%) strains, while the mecA gene was detected in as many as 180 (72%) isolates.
Źródło:
Journal of Water and Land Development; 2023, 56; 136--141
1429-7426
2083-4535
Pojawia się w:
Journal of Water and Land Development
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Culturable airborne bacteria and isolation of methicillin-resistant coagulase-negative staphylococci from outdoor environments on European side of Istanbul, Turkey
Autorzy:
Sivri, N.
Bağcıgil, A. F.
Metiner, K.
Şeker, D. Z.
Orak, S.
Durak, S. G.
Sönmez, V. Z.
Powiązania:
https://bibliotekanauki.pl/articles/204869.pdf
Data publikacji:
2016
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
antimicrobial resistance
culturable airborne bacteria
European side of Istanbul
GIS
Staphylococcus sp.
Opis:
This study is aimed to investigate culturable airborne bacteria concentrations and the composition of methicillin-resistant staphylococci in eleven different locations on the basis of specific activities conducted within different parts of the European side of Istanbul. The highest bacterial levels were observed at the Bakirkoy station (1 100 CFU/m3) while the second highest levels were found at the Bahcelievler station (1 040 CFU/m3) in October; the lowest levels (10 CFU/m3) were measured at other different stations (Atakoy, Yesilkoy). Fifteen methicillin-resistant isolates [Staphylococcus hominis (n=11), S. cohnii spp. cohnii (n=2), S. sciuri (n=1), S. capitis spp. capitis (n=1)] were identified. The disc diffusion method was used to identify the antimicrobial resistance of these isolates, it was observed that the most common resistance was to penicillin (P) (n=11), doxycycline (DO) (n=4) and tetracycline (T) (n=5). None of the isolates was resistant to imipenem, amoxicillin/clavulanic acid, vancomycin (IPM, AMC, VA). However, multiple antimicrobial resistance was found to be 26.7%. The results of this study revealed the importance of isolated methicillin-resistant staphylococci in the stations with densely active human population and traffic, for public health. As a result, the importance of resting along known shorelines, where culturable airborne bacteria concentrations are much lower, and its importance for human health have been emphasized.
Źródło:
Archives of Environmental Protection; 2016, 42, 3; 77-86
2083-4772
2083-4810
Pojawia się w:
Archives of Environmental Protection
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Molecular docking and pharmacokinetic prediction of phytochemicals from Syzygium cumini in interaction with penicillin-binding protein 2a and erythromycin ribosomal methylase of Staphylococcus aureus
Autorzy:
Shidiki, A.
Vyas, A.
Powiązania:
https://bibliotekanauki.pl/articles/2096259.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
methicillin-resistant S. aureus
penicillin-binding protein 2a
erythromycin ribosomal methylase
Opis:
Background. MRSA and MLSB resistant S. aureus are known as important pathogens, which are responsible for many cases of both hospital and community-acquired infections worldwide. Studying drug discovery from plant sources is regarded as an important prevention strategy regarding these types of infections. Material and methods. Agar well diffusion method was performed for antimicrobial evaluation, LCMS technique used for identification of different compounds, molecular docking performed by application of iGEMDOCK for PBP2a and ERM to plant compounds, and its pharmacokinetic evaluation of ADMET through use of AdmetSAR. Results. Water extract was the most effective against resistant strains of Staphylococcus aureus. Twenty compounds belonging to phenols, flavonoids, organic acids, terpenoids groups were reported. Eighteen plant compounds passed in Lipinski's rule of five. iGEMDOCK revealed diferulic acid has the least binding energy -102.37 kcal/mole to penicillin-binding protein 2a and taxifolin has the least binding energy of -103.12 kcal/mole to erythromycin ribosomal methylase in comparison to control linezolid. These compounds raise the potential for developing potent inhibitors of penicillin-binding protein 2a and erythromycin ribosomal methylase for drug development. ADMET properties revealed that eighteen studied compounds were found in category III and IV with non-toxic properties except two butin and taxifolin found in category II with toxic properties. Conclusions. It can be concluded that diferulic acid and taxifolin compounds provide the best inhibitor effect to PBP2a and ERM protein for inhibition of MRSA and MLSB resistant strains of S. aureus through the application of molecular docking, leading to a lead drug candidate for the treatment of diseases.
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2022, 103, 1; 5-18
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
First report of swine-associated methicillin-resistant Staphylococcus aureus ST398 in Lithuania
Autorzy:
Ruzauskas, M.
Couto, N.
Belas, A.
Klimiene, I.
Siugzdiniene, R.
Pomba, C.
Powiązania:
https://bibliotekanauki.pl/articles/30638.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
During 2011, 160 nasal samples were taken from pigs on 8 different farms in Lithuania. Four methicillin-resistant Staphylococcus aureus (MRSA) isolates were obtained. The isolates were ST398, spa type t011 and SCCmec V and none carried the lukF/lukS genes. Strains were resistant to tetracycline, attributed to tetK and tetM genes, and to erythromycin owing to the ermB gene. One MRSA strain was resistant to trimethoprim/sulfamethoxazole and carried the dfrK gene. This is the first report on the presence and characteristics of livestock-associated MRSA isolated from pigs in Lithuania.
Źródło:
Polish Journal of Veterinary Sciences; 2013, 16, 1
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Staphylococcus aureus as an infectious agent: overview of biochemistry and molecular genetics of its pathogenicity
Autorzy:
Plata, Konrad
Rosato, Adriana
Węgrzyn, Grzegorz
Powiązania:
https://bibliotekanauki.pl/articles/1040468.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Staphylococcus aureus
virulence
pathogenicity genes
toxins
methicillin resistance
Opis:
Although it is estimated that 20-30% of the general human population are carriers of Staphylococcus aureus, this bacterium is one of the most important etiological agents responsible for healthcare-associated infections. The appearance of methicillin resistant S. aureus (MRSA) strains has created serious therapeutical problems. Detailed understanding of the mechanisms of S. aureus infections seems necessary to develop new effective therapies against this pathogen. In this article, we present an overview of the biochemical and genetic mechanisms of pathogenicity of S. aureus strains. Virulence factors, organization of the genome and regulation of expression of genes involved in virulence, and mechanisms leading to methicilin resistance are presented and briefly discussed.
Źródło:
Acta Biochimica Polonica; 2009, 56, 4; 597-612
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Occupational acquisition of methicillin-resistant Staphylococcus aureus in humans – A description of MRSA carrier and infected cases from the Region of North Jutland in Denmark
Autorzy:
Omland, O.
Hoffmann, L.
Powiązania:
https://bibliotekanauki.pl/articles/51755.pdf
Data publikacji:
2012
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2012, 19, 4
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evidence of new sequence types of methicillin-resistant Staphylococcus pseudintermedius in Italy
Autorzy:
Nocera, F.P.
Parisi, A.
Corrente, M.
De Martino, L.
Powiązania:
https://bibliotekanauki.pl/articles/2087290.pdf
Data publikacji:
2020
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
methicillin-resistant S. pseudintermedius
canine skin diseases
Multi-Locus Sequence Typing
new sequence types
Źródło:
Polish Journal of Veterinary Sciences; 2020, 23, 3; 465-468
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Self-reported methicillin-resistant Staphylococcus aureus infection in USA pork producers
Autorzy:
Leedom, Larson K R
Smith, T.C.
Donham, K.J.
Powiązania:
https://bibliotekanauki.pl/articles/51288.pdf
Data publikacji:
2010
Wydawca:
Instytut Medycyny Wsi
Tematy:
pork production
pork producer
USA
animal farm
pig
agricultural worker
human disease
infection
methicillin-resistant Staphylococcus aureus
Staphylococcus aureus
Źródło:
Annals of Agricultural and Environmental Medicine; 2010, 17, 2; 331-334
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lack of correlation between X region spa polymorphism and virulence of methicillin resistant and methicillin sensitive Staphylococcus aureus strains
Autorzy:
Kurlenda, Julianna
Grinholc, Mariusz
Szweda, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1040442.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
polymorphism
protein A
spa
virulence
Opis:
Staphylococcus aureus is an etiological factor of severe infections in both hospital and ambulatory environments. As methicillin resistant Staphylococcus aureus strains spread quickly across healthcare centers resulting in life-threatening infections with increased mortality, they are considered more virulent than MSSA strains. Protein A, encoded by the spa gene, is one of the virulence factors involved in the staphylococcal pathogenesis. It has been suggested that the number of 24-bp tandem repeat units along the X region of the spa gene correlates with the virulence level of the strains. The current work analyzed the relationships between the virulence of MRSA and MSSA strains with region X polymorphism. No obvious correlation was observed.
Źródło:
Acta Biochimica Polonica; 2010, 57, 1; 135-138
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Kliniczne znaczenie metycylinoopornych szczepów Staphylococcus pseudintermedius w praktyce weterynaryjnej
Methicillin resistant Staphylococcus pseudintermedius strains in veterinary practice
Autorzy:
Kizerwetter-Swida, M.
Chrobak, D.
Rzewuska, M.
Binek, M.
Powiązania:
https://bibliotekanauki.pl/articles/859244.pdf
Data publikacji:
2013
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
choroby zwierzat
czynniki chorobotworcze
bakterie
Staphylococcus pseudintermedius
szczepy metycylinooporne
wystepowanie
chorobotworczosc
potencjal zoonotyczny
znaczenie kliniczne
wielolekoopornosc
wrazliwosc na antybiotyki
rifampicyna
minocyklina
chloramfenikol
amikacyna
wankomycyna
Źródło:
Życie Weterynaryjne; 2013, 88, 10
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antimicrobal susceptibility pattern of methicillin resistant Staphylococcus aureus isolatetd from pediatric clinical samples at Webuye District Hospital
Autorzy:
Kibaba, P. W.
Louis, H.
Kering, K. K.
Matiru, V. N.
Powiązania:
https://bibliotekanauki.pl/articles/1179606.pdf
Data publikacji:
2017
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Antimicrobial
MRSA
Staphyoloccocus aureus
Susceptibility
Opis:
Methicillin Resistant Staphylococcus aureus (MRSA) is an important nosocomial pathogen causing a significant mortality and morbidity. The main objective of the study was to establish antibiotic susceptibility pattern MRSA isolated from pediatrics clinical samples at Webuye District Hospital. A total of 96 clinical samples that include blood, abscess, ear swabs, and urine and wound/pus swabs were collected by simple random techniques. These samples were cultured onto Blood agar and MacConkey agar respectively and incubated at 37oC for 24 hours. In the result 83 (86.5%) clinical samples had pure colonies of S. aureus which were identified morphologically and biochemically by standard laboratory procedures using Bergey’s Manual of Clinical Microbiology. All confirmed positive isolates were screened for MRSA whereby 18 (21.7%) were MRSA and these were subjected to susceptibility testing to common antibiotics by modified Kirby-Bauer disc diffusion method. The susceptibility was interpreted according to National Clinical laboratory Standard guidelines. From the study the prevalence of MRSA was 18 (21.7%) with the highest obtained in the wound/pus swab. Almost all MRSA was resistant to penicillin (92.8%) and cephalexin (96.6%) and amoxicillin (91%). The most effective antibiotics against the of MRSA strain were vancomycin (98.97%), ciprofloxacin (88.4%) and gentamycin (83.06%). Vancomycin was the most effective drug showed the largest inhibition zone.
Źródło:
World Scientific News; 2017, 74; 238-250
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bactericidal effect of photodynamic therapy against methicillin-resistant Staphylococcus aureus strain with the use of various porphyrin photosensitizers
Autorzy:
Grinholc, Mariusz
Szramka, Bozena
Olender, Katarzyna
Graczyk, Alfreda
Powiązania:
https://bibliotekanauki.pl/articles/1041060.pdf
Data publikacji:
2007
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
photosensitizer
porphyrin
photodynamic therapy
MRSA
Opis:
Photodynamic therapy (PDT) is based on photosensitizers activated by light of appropriate wavelength. Their activation leads to generation of singlet oxygen and free radicals responsible for the cytotoxic effect. The aim of this project was to compare the bactericidal effect of PDT using different porphyrin photosensitizers against a methicillin-resistant Staphylococcus aureus strain. Exogenous sensitizers (protoporphyrin IX and newly synthesized derivative, protoporphyrin diarginate) induced a 3 log10-unit reduction in bacterial viable counts. With the use of endogenous, ALA-induced porphyrins, a 1.6 log10-unit reduction was obtained. The sensitizers tested executed their antibacterial activity with no essential change in the antibiotic resistance pattern of the studied strain.
Źródło:
Acta Biochimica Polonica; 2007, 54, 3; 665-670
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Photodynamic effect of protoporphyrin diarginate (PPArg2) on methicillin-resistant Staphylococcus aureus and human dermal fibroblasts
Autorzy:
Grinholc, Mariusz
Kawiak, Anna
Kurlenda, Julianna
Graczyk, Alfreda
Bielawski, Krzysztof
Powiązania:
https://bibliotekanauki.pl/articles/1040819.pdf
Data publikacji:
2008
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cytotoxicity
antimicrobial photodynamic inactivation
MRSA
fibroblasts
phototoxicity
Opis:
The worldwide rise in the antibiotic resistance of bacteria forces the development of alternative antimicrobial treatments. A potential approach is photodynamic inactivation (PDI). The aim of the present study was to determine the phototoxicity of protoporphyrin diarginate (PPArg2) against methicillin-resistant Staphylococcus aureus and human dermal fibroblasts. Different concentrations (0 to 20 µM) of PPArg2 and light dose of 6 J cm-2 were tested. Cell viability was evaluated using the methylthiazoletetrazolium (MTT) assay. Incubation with 10 µM followed by illumination yielded a 3.6 log10-unit reduction in the viable count for Staphylococcus aureus. At the same experimental conditions, only 22.5% of the fibroblasts were photoinactivated. Protoporphyrin diarginate at concentrations up to 20 µM demonstrated no toxicity towards S. aureus or fibroblasts when not irradiated. These results suggest that the protoporphyrin diarginate exerts a high bactericidal effect against methicillin-resistant S. aureus strain without harming eukaryotic cells.
Źródło:
Acta Biochimica Polonica; 2008, 55, 1; 85-90
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Heterogeneity of methicillin-sensitive Staphylococcus pseudintermedius strains isolated from diseased dogs
Autorzy:
Garbacz, K.
Piechowicz, L.
Zarnowska, S.
Haras, K.
Dabrowska-Szponar, M.
Powiązania:
https://bibliotekanauki.pl/articles/32033.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
animal disease
dog
heterogeneity
methicillin
Staphylococcus pseudintermedius
isolation
diseased animal
pulsed-field gel electrophoresis
Opis:
Thirty nine canine S. pseudintermedius strains were examined for antibiotic susceptibility and genetic polymorphisms. All strains were methicillin-sensitive S. pseudintermedius (MSSP). Resistance to penicillin was most prevalent (66.6%), followed by resistance to neomycin (56.4%), erythromycin (53.8%), clindamycin (48.7%), chloramphenicol (48.7%), and tetracycline (46.2%). Pulsed-field electrophoresis (PFGE) showed a high genetic polymorphism in the investigated strains.
Źródło:
Polish Journal of Veterinary Sciences; 2011, 14, 2
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Production of bioactive metabolites from different marine endophytic Streptomyces species and testing them against methicillin-resistant Staphylococcus aureus (MRSA) and cancer cell lines
Autorzy:
El-Gendy, M.M.A.A.
Mohamed, Z.K.
Hekal, N.Z.
Ali, F.M.
Yousef, A.E.M.
Powiązania:
https://bibliotekanauki.pl/articles/81078.pdf
Data publikacji:
2018
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Staphylococcus aureus
infection
methicillin-resistant Staphylococcus aureus
endophyte
Streptomyces
bioactive metabolite
Actinomycetes
marine invertebrate
anticancer activity
cancer cell line
lung cancer
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2018, 99, 1
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 20

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies