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Wyszukujesz frazę "low-molecular weight chitosan" wg kryterium: Wszystkie pola

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    Wyświetlanie 1-3 z 3
    Tytuł:
    Differential effects of low and high molecular weight chitosan administered intraperitoneally to mice infected with heligmosomoides polygyrus
    Autorzy:
    Brodaczewska, Klaudia
    Doligalska, Maria
    Powiązania:
    https://bibliotekanauki.pl/articles/1035329.pdf
    Data publikacji:
    2013
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan
    immune response
    parasite
    Opis:
    Aim of the study was to compare the effect of different molecular weight chitosan on activity of peritoneal cells of mice during immunosupression caused by adult stages of Heligmosomoides polygyrus. We observed that intraperitoneal injections of chitosan induce cell infiltration, but the activity of recruited cells differed depending on the type of polysaccharide used. Low molecular weight chitosan activated cells with inflammatory characteristics, while high molecular weight polysaccharide reduced cell responsiveness to stimulation. Although IgA titers in the peritoneal fluid were elevated, chitosan treatments had no effect on the level of infection.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2013, 18, 18; 77-83
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Process of continuous production of oligoaminosaccharides in a column reactor
    Autorzy:
    Struszczyk, Katarzyna
    Szczęsna- Antczak, Mirosława
    Pomianowska, Emilia
    Stańczyk, Łukasz
    Wojciechowska, Justyna
    Antczak, Tadeusz
    Powiązania:
    https://bibliotekanauki.pl/articles/1035558.pdf
    Data publikacji:
    2010
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    Mucor
    chitooligosaccharides
    chitosan
    chitosanolytic enzymes
    continuous process.
    low-molecular weight chitosan
    Opis:
    A continuous production of oligoaminosaccharides from chitosan was achieved with a column reactor packed with chitosanolytic enzymes-containing mycelia of Mucor circinelloides and Mucor racemosus immobilized in porous carriers. The efficient work of the bed used for chitosan hydrolysis in a column reactor lasted for several or more than 10 days and depended on a type of a carrier and substrate concentration. Because a crucial parameter for large scale applications of enzymes is their operating stability, presented research intended to improve it through stabilization of proteins and elimination of their leakage from the carrier. Cross-linking of mycelial preparations of chitosanolytic enzymes with 1% glutaraldehyde did not increase their stability and further process optimization is necessary.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2010, 15; 177-188
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The inhibition of human platelet aggregation by a low-molecular weight chitosan
    Autorzy:
    Drozd, Natalia N
    Logvinova, Yulia S.
    Shagdarova, Balzhima Ts.
    Il’ina, Alla V.
    Varlamov, Valery P.
    Powiązania:
    https://bibliotekanauki.pl/articles/1034373.pdf
    Data publikacji:
    2018
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan
    deacetylation degree
    depolymerisation
    molecular weight
    platelet aggregation
    Opis:
    Chitosan derivatives were obtained by chemical (MW of 6 kDa, DD 99% - Ch6/99; MW13 kDa, DD 98% - Ch13/98) and enzymatic (MW of 5 kDa, DD 85% - Ch5/85; MW of 10 kDa, DD 85% - Ch10/85) depolymeri-sation of chitosan with a MW of 334 and 1000 kDa. Chitosan derivatives (almost identical MW pairs and different DD) possessed insignificant an-ticoagulant activity, did not promote human platelet aggregation and re-duced ADP or collagen-induced platelet aggregation. The studied sam-ples at a concentration of 2 mg/ml reduced the aggregation of platelets more than twice induced in 2x10-6M and 1x10-5M concentrations; at weak activation in 2x10-6M, the Ch10/85 sample was the most effective. The Ch6/99 and Ch13/98 samples were 20 times more effective at the inhibi-tion of collagen-induced platelet aggregation than the Ch10/85 sample. The latter can be explained by the greater value of positive charge (DD) and polydispersity (Mw/Mn) of chitosan samples obtained by chemical de-polymerisation
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2018, 23; 55-65
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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