- Tytuł:
- Zmiana odpowiedzi immunologicznej u myszy BALB/c w koinwazji Heligmosomoides polygyrus i Trichinella spiralis
- Autorzy:
-
Doligalska, M
Rzepecka, J.
Moskwa, B.
Laskowska, M. - Powiązania:
- https://bibliotekanauki.pl/articles/839517.pdf
- Data publikacji:
- 2001
- Wydawca:
- Polskie Towarzystwo Parazytologiczne
- Tematy:
-
odpowiedz immunologiczna
koinwazja
zwierzeta doswiadczalne
Trichinella spiralis
parazytologia
myszy
Heligmosomoides polygyrus
nicienie
pasozyty
inwazja pasozytnicza - Opis:
- The influence of Heligmosomoides polygyrus on infection with Trichinella spiralis was studied in BALB/c mice. Mice coinfected with T. spiralis and previously given H. Polygyrus harboured both nematode species till day 34. The number of T. spiralis muscle larvae was greater in mice coinfected with H. polygyrus/T. spiralis or T. spiralis/H. polygyrus than after infection with T. spiralis alone. Infection with H. polygyrus did not enhance eosinophil and IL-5 levels induced by T. spiralis. Additionally, the production of IgG1 specific to LI T. spiralis was inhibited by co-infection. Changes in the levels of IFN-y and IgG2a implicated a disturbance in Th2 cell activation during protective response and resulted in the greater number of T. spiralis muscle larvae in coinfected mice.
- Źródło:
-
Annals of Parasitology; 2001, 47, 4; 735-739
0043-5163 - Pojawia się w:
- Annals of Parasitology
- Dostawca treści:
- Biblioteka Nauki