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Tytuł:
Przeciwciała anty-HBc klasy IgM jako marker ostrego wirusowego zapalenia wątroby typu B
Antitela anti-HBc klassa IgM kak marker ostrogo virusnogo gepatita tipa B
Anti-HBc IgM class antibodies as a marker of acute virus hepatitis
Autorzy:
Własiuk, M.
Powiązania:
https://bibliotekanauki.pl/articles/2187827.pdf
Data publikacji:
1986
Wydawca:
Polskie Towarzystwo Diagnostyki Laboratoryjnej
Źródło:
Diagnostyka Laboratoryjna; 1986, 22, 2-3; 102-113
0867-4043
Pojawia się w:
Diagnostyka Laboratoryjna
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Use of an IgM-ELISA for diagnosis of acute toxoplasmosis
Stosowanie testu ELISA-IgM w diagnostyce ostrej toksoplazmozy
Autorzy:
Wielaard, F.
Powiązania:
https://bibliotekanauki.pl/articles/838344.pdf
Data publikacji:
1988
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
ELISA test
diagnosis
acute toxoplasmosis
toxoplasmosis
Toxoplasma gondii
parasite
infection
antibody
Opis:
Wyniki czterech serii badań (kilkaset prób surowicy) dokumentują przydatność testu ELISA-IgM firmy Organon-Toxonostika w diagnozowaniu toksoplazmozy. Wysoka specyficzność (99,7%, 97%) testu metodą wychwytywania = wiązania przeciwciał (,,antibody-capture") wynika z faktu, że przeciwciała Ig zostają wydzielone z innych białek surowicy przy pomocy unieruchomionych przeciwciał anty-IgM.
Źródło:
Annals of Parasitology; 1988, 34, 3
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Use of an IgM-ELISA for diagnosis of acute toxoplasmosis
Stosowanie testu ELISA-IgM w diagnostyce ostrej toksoplazmozy
Autorzy:
Wielaard, F.
Powiązania:
https://bibliotekanauki.pl/articles/2152632.pdf
Data publikacji:
1988
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
ELISA test
diagnosis
acute toxoplasmosis
toxoplasmosis
Toxoplasma gondii
parasite
infection
antibody
Opis:
Wyniki czterech serii badań (kilkaset prób surowicy) dokumentują przydatność testu ELISA-IgM firmy Organon-Toxonostika w diagnozowaniu toksoplazmozy. Wysoka specyficzność (99,7%, 97%) testu metodą wychwytywania = wiązania przeciwciał (,,antibody-capture") wynika z faktu, że przeciwciała Ig zostają wydzielone z innych białek surowicy przy pomocy unieruchomionych przeciwciał anty-IgM.
Źródło:
Wiadomości Parazytologiczne; 1988, 34, 3; 255-258
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
IgM multiple myeloma: diagnostic difficulties and results of bortezomib treatment – case report
Autorzy:
Machowicz, Rafał
Skwierawska, Kamila
Mądry, Krzysztof
Górka, Michał
Żurawska, Jagoda
Kacprzyk, Piotr
Waszczuk-Gajda, Anna
Dwilewicz-Trojaczek, Jadwiga
Powiązania:
https://bibliotekanauki.pl/articles/773502.pdf
Data publikacji:
2014
Wydawca:
Medical Education
Tematy:
IgM
Waldenström’s macroglobulinemia
bortezomib
multiple myeloma
Opis:
The IgM paraprotein secretion is most frequently associated with Waldenström’s macroglobulinemia. In very rare cases it may also occur in multiple myeloma. The diagnostic and therapeutic process of a 84 year old male suffering from IgM multiple myeloma is described, including difficulties in establishing this diagnosis. Due to infectious complications, after the first cycle of melphalan– prednisone–bortezomib treatment, melphalan was stopped, subsequently, bortezomib and prednisone doses were also reduced. Two treatment interruptions have occurred. Despite reduced treatment intensity, the patient was in very good partial remission, while the toxicity profile was acceptable. IgM multiple myeloma should be included in the differential diagnosis of IgM paraproteinemia, also when osteolytic lesions and translocation 11:14 are not detected. Bortezomib-based therapy can be effective in elderly patients (also in those suffering from cardiac insufficiency), even when dose reduction is required.
Źródło:
OncoReview; 2014, 4, 4; A160-A164
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Activity of specific IgG, IgM and IgE antibodies in human trichinellosis
Aktywność swoistych przeciwciał IgG, IgM i IgE we włośnicy człowieka
Autorzy:
Tomasik, J.
Grzybowski, J.
Golińska, Z.
Prokopowicz, D.
Powiązania:
https://bibliotekanauki.pl/articles/2152263.pdf
Data publikacji:
1992
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
wlosnica
choroby inwazyjne
przeciwciala swoiste
parazytologia
immunologia
aktywnosc immunologiczna
pasozyty czlowieka
Opis:
The activity of IgG, IgM and IgE antibodies to somatic antigen of Trichinella spiralis in the sera of patients with trichinellosis at various intervals after infection was examined by means of ELISA. Mathematical analysis of the dose-response curves was used. Elevated level of IgG and IgM antibodies of relatively high avidity and of rather low IgE avidity was documented. Amount or avidity ofIgG antibodies was found to be most useful for the diagnosis of trichinellosis (85% positive results in patients' sera). The isotype of IgM avidity constitutes a better diagnostic value than the amount of it (60% and 35% of positive results, respectively).
Źródło:
Wiadomości Parazytologiczne; 1992, 38, 3-4; 127-133
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hepatitis A seroprevalence in Erzurum, Turkey
Autorzy:
Yilmaz, A.
Powiązania:
https://bibliotekanauki.pl/articles/2085946.pdf
Data publikacji:
2020
Wydawca:
Instytut Medycyny Wsi
Tematy:
Hepatitis A
HAV IgG
HAV IgM
risk factor
prevalence
Opis:
Introduction and objective. Hepatitis A Virus (HAV), reportedly the most common cause of acute viral hepatitis in developing countries, infects millions of people worldwide each year. The aim of the study is to investigate the seropositivity of anti-hepatitis A virus (HAV) IgG and IgM in all age groups in Erzurum, and to determine the effect of various factors such as age, gender, climatic conditions and HAV vaccination (included in 2012 in the National Immunization Schedule on seroprevalence) on the seropositivity. Materials and method. The serological results of 25,007 individuals referred to Erzurum Public Health Microbiology Laboratory between January 2015 – December 2018 were retrospectively reviewed to test for the presence of anti-HAV IgG and IgM. The patient ages were 0–93 years. Serum samples were analyzed by ELISA. S/CO values of ≥1.00 and >1.21 were considered positive for anti-HAV IgG and IgM, respectively; results below this value were considered negative. Results. Anti-HAV IgG and IgM seropositivities were 87.3% and 0.2%, respectively. Anti-HAV IgG prevalence – 88.5% and 86.4%, anti-HAV IgM positivity – 0.1% and 0.3% in men and women. Anti-HAV IgG seroprevalence – 87%, 73.2%, 58.7%, 75.2%, 86.1%, 89.8%, 96.1%, 99.1%, 99.1% and 99.3%, respectively, at 0–4, 5–9 10–14, 15–19, 20–24, 25–29, 30–39, 40–49, 50–59 and >60 age groups. Anti-HAV IgM seropositivity – 0, 0.1%, 0.7%, 0.7%, 0.3%, 0, 0.1%, 0.2%, 0.1%, and 0.2%, respectively, in the same age groups. Anti-HAV IgM positivity was the highest in November – 36(0.97%. Conclusion. In Erzurum, anti-HAV IgG prevalence is tremendously high, whereas prevalence of anti-HAV IgM is exceptionally low, especially in the paediatric age group. Therefore, HAV vaccine is provided free of charge in Turkey, including Erzurum, since 2012.
Źródło:
Annals of Agricultural and Environmental Medicine; 2020, 27, 3; 481-484
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Activity of specific IgG, IgM and IgE antibodies in human trichinellosis
Aktywnosc swoistych przeciwcial IgG, IgM i IgE we wlosnicy czlowieka
Autorzy:
Tomasik, J
Grzybowski, J.
Golinska, Z.
Prokopowicz, D.
Powiązania:
https://bibliotekanauki.pl/articles/841299.pdf
Data publikacji:
1992
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
wlosnica
choroby inwazyjne
przeciwciala swoiste
parazytologia
immunologia
aktywnosc immunologiczna
pasozyty czlowieka
Opis:
The activity of IgG, IgM and IgE antibodies to somatic antigen of Trichinella spiralis in the sera of patients with trichinellosis at various intervals after infection was examined by means of ELISA. Mathematical analysis of the dose-response curves was used. Elevated level of IgG and IgM antibodies of relatively high avidity and of rather low IgE avidity was documented. Amount or avidity ofIgG antibodies was found to be most useful for the diagnosis of trichinellosis (85% positive results in patients' sera). The isotype of IgM avidity constitutes a better diagnostic value than the amount of it (60% and 35% of positive results, respectively).
Źródło:
Annals of Parasitology; 1992, 38, 3-4; 127-133
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zastosowanie metody ISAGA w wykrywaniu swoistych przeciwciał IgM, IgA, IgE w nabytej i wrodzonej toksoplazmozie
IMMUNOSORBENT AGGLUTINATION ASSAY (ISAGA) IN DETECTION OF SPECIFIC IgM, IgA, AND IgE ANTIBODIES IN ACQUIRED AND CONGENITAL TOXOPLASMOSIS
Autorzy:
Paul, M.
Powiązania:
https://bibliotekanauki.pl/articles/2148892.pdf
Data publikacji:
1997
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
toksoplazmoza
choroby pasozytnicze
przeciwciala swoiste
metody serologiczne
immunoglobulina M
parazytologia
immunoglobulina A
immunoglobulina E
metoda ISAGA
wykrywanie
Toxoplasma gondii
pasozyty czlowieka
Opis:
Immunocapture assays ISAGA PLUS IgA/IgM (bioMerieux) and IgE ISAGA were used to determine their usefulness in the diagnosis of acquired and congenital toxoplasmosis. Specific IgM, IgA and IgE antibodies were tested in 134 patients, namely pregnant women who seroconverted during gestation (n= 20), children with congenital toxoplasmosis (n= 5), patients with toxoplasmic lymphadenitis (n= 56) and immunocompetent individuals with chronic Toxoplasma gondii infection (n= 53). Altogether 172 sera were examined. Specific IgM antibodies were detected in all sera from pregnant women (100%) with recent T. gondii infection (1- 8 weeks after seroconversion), in all patients with toxoplasmic lymphadenopathy (1-3 months after onset of symptoms) and in their control examinations after 2 and 5 months (100%) and also in 35 (66%) out of 53 patients with chronic infection. In infants with congenital toxoplasmosis IgM were found only in one new-born; equivocal results were obtained in 3 children during the asymptomatic serological reactivation in the second year of life. Specific IgA antibodies were present in sera from 15 (75%) out of 20 women seroconverted during pregnancy; in 3 cases the results were equivocal. IgA antibodies were detected in sera from 30 (81.1%) out of 37 patients with toxoplasmic lymphadenitis examined once; in 19 patients examined 3 times IgA antibodies were present in all the cases in the first serological examination performed when clinical symptoms were first observed (100%), in 17 patients after 2 months (89.5%) and in 11 patients after 5 months (57.9%). IgA antibodies were also detected in 21 sera (39.6%) from patients with chronic T. gondii infection. In children with congenital toxoplasmosis IgA antibodies were found in 3 cases during serological reactivation after discontinuation of pyrimethamine-sulfadiazine therapy; in these cases equivocal results of IgM antibodies were present, and positive result of IgE antibodies in one case. Specific IgE antibodies were detected in sera from 17 (85%) out of 20 women with seroconversion and in 18 patients with lymphadenopathy (32.1%); in the last group IgE antibodies were not present in the follow-up examination after 5 months. IgE antibodies were detected only in 5 cases (9.4%) with chronic infection. IgA and IgE antibodies in ISAGA begin to appear about a week later than IgM antibodies; in sera collected between the 2nd and 3rd week after invasion the positive results were obtained in all cases (100%). Therefore, ISAGA PLUS IgA/IgM (bioMerieux) is useful for the diagnosis of recent T. gondii infection especially in women with suspected seroconversion during pregnancy. ISAGA PLUS IgA/IgM is more sensitive than any conventional method routinely used and so far is a specially eflicient technique for newborns and infants suspected for congenital infection and/or in diagnosing congenital toxoplasmosis during immunological recrudescence. This test has a limited value in toxoplasmosis with lymphadenopathy by reason of possibility of a long persistence of IgM and IgA antibodies detected by ISAGA. Detection of specific IgE antibodies using ISAGA technique may be useful for differential diagnosis of acute and chronic phase of T. gondii infection and also in some cases of serological reactivation of congenital toxoplasmosis.
Źródło:
Wiadomości Parazytologiczne; 1997, 43, 1; 39-51
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Amino acid composition of the µ chains of IgM of normal serum, monoclonal cryoglobulin and Waldenström macroglobulin
Autorzy:
Tomaszewski, Jeremiasz
Woźniak, Krystyna
Kimak, Eliżbieta
Powiązania:
https://bibliotekanauki.pl/articles/1046168.pdf
Data publikacji:
1980
Wydawca:
Polskie Towarzystwo Biochemiczne
Źródło:
Acta Biochimica Polonica; 1980, 27, 3-4; 295-301
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Emerging and detection of Dengue viral infection in Sri Lanka
Autorzy:
Amarakoon, A. A. D. Gayathri Upeksha
Powiązania:
https://bibliotekanauki.pl/articles/1188088.pdf
Data publikacji:
2016
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
IgG
RT-PCR
IgM
acute infection
Aedes mosquitos
Opis:
Emerging of dengue infection has increased dramatically in Sri Lanka in recent years. Initial infection with a particular serotype is known as primary infection which is usually asymptomatic or mild disease manifestations. Although cross reactive T cells and cross reactive antibodies have been shown to contribute to disease pathogenesis, these mechanisms alone do not explain the immune - pathological mechanisms leading to severe infection. However, this study has suggested that antigen antibody detection and viral RNA detection in host blood contribute to the occurrence of disease. Therefore, it is important to further investigate the quality of dengue specific immune responses and confirmation of dengue RNA content in patients with acute severe dengue and asymptomatic dengue infection.
Źródło:
World Scientific News; 2016, 56; 97-109
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antibody - Biological warfare agents
Autorzy:
Mayrolle, Pierre
Kuillon, Jean Michel
Kuéry, Sareleï
Aulin, Vincent
Kirondot, Marc
Powiązania:
https://bibliotekanauki.pl/articles/1119235.pdf
Data publikacji:
2016
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Immunoglobulin A (IgA)
Immunoglobulin G (IgG)
Polyclonal antibodies (PAb)
antibody production
antibody (Ab)
immunoglobulin M (IgM)
Opis:
An antibody (Ab), also known as immunoglobulin (Ig), is a large Y-shape protein consisting of two heavy chains and two light chains (Figure 1) which form a functionally bivalent monomer that is produced by B cells receptor used by the immune system to identify and neutralize foreign objects such as bacteria and viruses. Current widely used rapid detection systems exploit antibodies for recognition, identification and quantification of target analytes [68]. Abs played an important role in the advancement of diagnostic assays, making these indispensable in diagnostic tests that are commonly used routinely in clinics in classical immunological methods such as ELISA, dot blot immunobinding assays, electro-chemiluminescence, flow cytometry and several microscopic techniques like fluorescence, as well as in the construction of numerous immunosensors. Immunoglobulin M (IgM) usually exists as a pentamer in mammals that predominates in primary immune responses to most antigens, and is the most efficient complement fixing immunoglobulin. It comprises approximately 10% of all normal human serum Ig content. IgM is mainly produced by the immune system for protection against numerous viral, bacterial, fungal and parasitic infections.
Źródło:
World News of Natural Sciences; 2016, 5; 1-19
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rapid serological tests for SARS-CoV-2 IgG/IgM – not worth attention?
Autorzy:
Krygier, Rafał
Stępień, Piotr M.
Zarębska-Michaluk, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/2086077.pdf
Data publikacji:
2021-05-27
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
RT-PCR
screening
employees
COVID-19
SARS-CoV-2
rapid serological tests
Opis:
ObjectivesCoronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome virus 2 (SARS-CoV-2) had spread worldwide since December 2019 and became a pandemic in March 2020. The diagnosis of an active infection is based on the real-time reverse transcriptase-polymerase chain reaction (RT-PCR) from the nasopharyngeal swab specimen. The aim of the current analysis was to assess the usefulness of the rapid serological tests for diagnosing SARS-CoV-2 infections.Material and MethodsThe rapid serological tests detecting IgG/IgM antibodies for SARS-CoV-2 were voluntarily performed in asymptomatic employees of 2 companies. The examination was conducted at the date and time selected online by the study participants. The testing team consisted of 2 nurses collecting the samples and 1 doctor who interpreted the results. Each positive rapid test result was verified by an RT-PCR examination from a nasopharyngeal swab. The testing kits named Vazyme: 2019-nCoV IgG/IgM Detection Kit (Colloidal Gold-Based) were provided by the employer along with the manual and certificates.ResultsThe overall interest in testing among employees was below the employer’s expectations and reached 30% and 20% in each of the 2 companies, respectively. A total of 516 participants were included in the analysis. Ten positive results of the rapid tests were documented, including 7 for IgM and 3 for IgG antibodies. No positive result was confirmed by the detection of the genetic material of the SARS-CoV-2 by the RT-PCR examination.ConclusionsHerein, the authors demonstrated the uselessness of rapid serological tests performed in asymptomatic volunteers for diagnosing SARS-CoV-2 infections.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2021, 34, 2; 203-209
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Serum levels of anti-corona virus specific-IgG and -IgM antibodies in COVID-19 patients at admission and at discharge
Autorzy:
Olatunbosun Arinola, Ganiyu
Powiązania:
https://bibliotekanauki.pl/articles/2040148.pdf
Data publikacji:
2021-03-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
anti-SARS-CoV-2 specific antibodies convalescence plasma
COVID-19
spike protein
vaccine
Opis:
Introduction. Clear understanding of duration of antibody based protective immunity following natural infection with SARSCoV-2 will give idea about the efficacy of proposed prophylactic vaccines against SARS-CoV-2, establishment of herd immunity and use of convalescent plasma. Aim. This study clarified the kinetics and magnitude of the initial antibody response against SARS-CoV-2 in a cohort of symptomatic COVID-19 patients from Ibadan, Nigeria. Material and methods. This study quantified immunoglobulin M (IgM) and G (IgG) antibodies recognizing the SARS-CoV-2 Spike (S) protein in 35 symptomatic COVID-19 patients at admission and at discharge using ELISA. Results. CovIgG was positive in none (0)% and 20% of COVID-19 patients at admission and at discharge respectively while CovIgM was positive in 54% and 69% of COVID-19 patients at admission and at discharged respectively. The level of CovIgG was significantly higher in COVID-19 patients at discharge compared with the level at admission while the level of CovIgM was insignificantly reduced in COVID-19 patients at discharge compared with the level at admission. Conclusion. The data indicates increased anti-SARS-COV-2 IgG Spike antibody in symptomatic COVID-19 at discharge, thus providing basis for antibody-based therapies to treat COVID-19 patients
Źródło:
European Journal of Clinical and Experimental Medicine; 2021, 1; 5-9
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zastosowanie metody ISAGA w wykrywaniu swoistych przeciwcial IgM, IgA, IgE w nabytej i wrodzonej toksoplazmozie
Autorzy:
Paul, M
Powiązania:
https://bibliotekanauki.pl/articles/839324.pdf
Data publikacji:
1997
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
toksoplazmoza
choroby pasozytnicze
przeciwciala swoiste
metody serologiczne
immunoglobulina M
parazytologia
immunoglobulina A
immunoglobulina E
metoda ISAGA
wykrywanie
Toxoplasma gondii
pasozyty czlowieka
Opis:
Immunocapture assays ISAGA PLUS IgA/IgM (bioMerieux) and IgE ISAGA were used to determine their usefulness in the diagnosis of acquired and congenital toxoplasmosis. Specific IgM, IgA and IgE antibodies were tested in 134 patients, namely pregnant women who seroconverted during gestation (n= 20), children with congenital toxoplasmosis (n= 5), patients with toxoplasmic lymphadenitis (n= 56) and immunocompetent individuals with chronic Toxoplasma gondii infection (n= 53). Altogether 172 sera were examined. Specific IgM antibodies were detected in all sera from pregnant women (100%) with recent T. gondii infection (1- 8 weeks after seroconversion), in all patients with toxoplasmic lymphadenopathy (1-3 months after onset of symptoms) and in their control examinations after 2 and 5 months (100%) and also in 35 (66%) out of 53 patients with chronic infection. In infants with congenital toxoplasmosis IgM were found only in one new-born; equivocal results were obtained in 3 children during the asymptomatic serological reactivation in the second year of life. Specific IgA antibodies were present in sera from 15 (75%) out of 20 women seroconverted during pregnancy; in 3 cases the results were equivocal. IgA antibodies were detected in sera from 30 (81.1%) out of 37 patients with toxoplasmic lymphadenitis examined once; in 19 patients examined 3 times IgA antibodies were present in all the cases in the first serological examination performed when clinical symptoms were first observed (100%), in 17 patients after 2 months (89.5%) and in 11 patients after 5 months (57.9%). IgA antibodies were also detected in 21 sera (39.6%) from patients with chronic T. gondii infection. In children with congenital toxoplasmosis IgA antibodies were found in 3 cases during serological reactivation after discontinuation of pyrimethamine-sulfadiazine therapy; in these cases equivocal results of IgM antibodies were present, and positive result of IgE antibodies in one case. Specific IgE antibodies were detected in sera from 17 (85%) out of 20 women with seroconversion and in 18 patients with lymphadenopathy (32.1%); in the last group IgE antibodies were not present in the follow-up examination after 5 months. IgE antibodies were detected only in 5 cases (9.4%) with chronic infection. IgA and IgE antibodies in ISAGA begin to appear about a week later than IgM antibodies; in sera collected between the 2nd and 3rd week after invasion the positive results were obtained in all cases (100%). Therefore, ISAGA PLUS IgA/IgM (bioMerieux) is useful for the diagnosis of recent T. gondii infection especially in women with suspected seroconversion during pregnancy. ISAGA PLUS IgA/IgM is more sensitive than any conventional method routinely used and so far is a specially eflicient technique for newborns and infants suspected for congenital infection and/or in diagnosing congenital toxoplasmosis during immunological recrudescence. This test has a limited value in toxoplasmosis with lymphadenopathy by reason of possibility of a long persistence of IgM and IgA antibodies detected by ISAGA. Detection of specific IgE antibodies using ISAGA technique may be useful for differential diagnosis of acute and chronic phase of T. gondii infection and also in some cases of serological reactivation of congenital toxoplasmosis.
Źródło:
Annals of Parasitology; 1997, 43, 1; 39-51
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Upper respiratory tract infections and influenza-like illnesses among healthcare workers: are serological tests useful in monitoring influenza and influenza-like illness?
Autorzy:
Toczek-Kubicka, Katarzyna
Szenborn, Filip
Kuchar, Ernest P.
Szenborn, Leszek
Powiązania:
https://bibliotekanauki.pl/articles/2153866.pdf
Data publikacji:
2022-12-29
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
IgM antibodies
vaccination
humoral response
influenza
healthcare workers
influenza-like illness
Opis:
Background Healthcare workers (HCWs) are at high risk for exposure to upper respiratory tract infections (URTIs) and influenza-like illnesses (ILIs). The present study aimed to surveil URTIs and ILIs and their impact among the Department of Pediatric Infectious Diseases in Wroclaw employees and evaluate their humoral response to influenza. Material and Methods Thirty-six HCWs participated in the first season and 32 HCWs in the second season during years of the study. The authors carried out a URTI/ILI surveillance, and all HCWs were asked to complete a weekly report during 2 influenza seasons: 2016/2017 (S1) and 2017/2018 (S2). In S1 both IgG and IgM antibodies against influenza A and B were assessed. The HCWs with symptoms of ILI were encouraged to undergo PCR tests for influenza. Results No significant differences in reporting URTI were found among vaccinated and non-vaccinated HCWs and HCWs and the control group. Depending on the year 5.5–17.2% of HCWs were treated with antibiotics because of URTI. In the study 58.7% of participants in S1 and 66.7% in S2 decide to work despite the URTI symptoms. There was no statistical relationship between the concentration of anti-influenza IgG and the number of URTIs and ILIs reported. Only vaccinated were willing to undergo voluntary influenza testing. Conclusions The URTI and ILI occur commonly in HCWs, and HCWs contract URTIs as often as the control group. Despite their medical education, HCWs work with the symptoms of infection and overuse antibiotics to treat the URTI. Serology testing is not able to follow the infection’s dynamics or identify the people immune to the influenza-like illness. The diagnostic value of IgM antibodies in acute influenza infection is negligible. Vaccinated HCWs are more focused on their health and are more willing to undergo influenza tests.
Źródło:
Medycyna Pracy; 2022, 73, 6; 441-447
0465-5893
2353-1339
Pojawia się w:
Medycyna Pracy
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 20

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