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Wyszukujesz frazę "hemoglobin" wg kryterium: Wszystkie pola


Tytuł:
Flavonoids as reductants of ferryl hemoglobin
Autorzy:
Gebicka, Lidia
Banasiak, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1040549.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
methemoglobin
ferryl hemoglobin
oxyhemoglobin
flavonoids
Opis:
The ferryl derivatives of hemoglobin are products of the reactions of oxy- and methemoglobin with hydrogen peroxide. Ferryl hemoglobins, either with or without a radical site on the protein moiety, are oxidizing species. Plant polyphenols, flavonoids, have been shown to act as antioxidants in vivo and in vitro. Reactions of met- and oxyhemoglobin with hydrogen peroxide in the presence of catechin, quercetin and rutin were studied. These flavonoids accelerated reduction of ferryl hemoglobin to methemoglobin. The rate constants of the reactions of ferryl hemoglobin with catechin, quercetin and rutin were in the order of 102 M-1 s-1, i.e. similar to the rate constants of ferryl hemoglobin with intracellular reducing compounds like urate or ascorbate. The beneficial effect of flavonoids against oxidative damage of hemoglobin caused by hydroperoxides, reported in the literature, is probably, at least in part, connected with the ability of flavonoids to scavenge ferryl hemoglobin.
Źródło:
Acta Biochimica Polonica; 2009, 56, 3; 509-513
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hemoglobiny bakterii
The bacterial hemoglobin
Autorzy:
Gondko, Roman
Powiązania:
https://bibliotekanauki.pl/articles/945106.pdf
Data publikacji:
1991
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Opis:
The aim of this paper is to summarize the publications concerning the bacterial hemoglobin (Vitreoscilla). This is the first bacterial hemoglobin to be sequenced and physicochemical properties are determined. It showed the maximum sequence homology (24%) with lupin leghemoglobin (Lg) which properties also have been presented. Bacterial hemoglobin may function to enable the organism to survive in oxygen-limited environments by acting as an oxygen storage-trap or to facilitate oxygen diffusion.
Źródło:
Acta Universitatis Lodziensis. Folia Biochimica et Biophysica; 1991, 8
0208-614X
Pojawia się w:
Acta Universitatis Lodziensis. Folia Biochimica et Biophysica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Determination of serum iron levels and hemoglobin concentration in pre-weaning calves
Autorzy:
Geboliszova, K.
Kadek, R.
Illek, J.
Powiązania:
https://bibliotekanauki.pl/articles/1192775.pdf
Data publikacji:
2021
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
Tematy:
calves
milk diet
iron
hemoglobin
Opis:
The aim of this study was to evaluate the serum iron (Fe) levels and hemoglobin (Hb) values in Holstein-Friesian calves with different types of milk diet. In total, 20 dairy calves (10 from each farm) were used for the experiment on two dairy farms. One farm provided the calves with a milk replacer twice a day from day 3 until weaning (farm 1), and the other one fed the calves native milk twice a day for three weeks before the milk replacer was administered (farm 2). Blood samples were collected three times, first at the age of 2-7 days, second time at the age of 30 days and last time at the age of 56 - 60 days, for the determination of iron and hemoglobin levels. Our experiment included monitoring of the occurrence of diarrheal and respiratory diseases in all calves. Values of serum iron and hemoglobin during the first sampling on farm 1: Fe 33.18 µmol l-1 (±29.39) and Hb 83.7 g l-1 (±11. 35); farm 2: Fe 8.38 µmol l-1 (±7.90) and Hb 90. 4 g l-1(±8.36). Second sampling on farm 1: Fe 37.35 µmol l-1 (±23.40) and Hb 106 g l-1 (±9.30); farm 2: Fe 5.62 µmol l-1 (±3.42) and Hb 80.3 g l-1 (±16.59). Last time on farm 1 the results were: Fe 42.69 µmol l-1 (±13.50) and Hb 101.0 g l-1 (±6.88); farm 2: Fe 32.79 µmol l-1 (±16. 07) and Hb 89.9 g l-1 (±6. 71). No respiratory diseases were observed on either farm during this study, diarrheal diseases occurred five times on farm 1 and nine times on farm 2. The results show that iron deficiency and lower hemoglobin concentration are more prevalent in animals fed whole milk.
Źródło:
Journal of Elementology; 2021, 26, 1; 261-270
1644-2296
Pojawia się w:
Journal of Elementology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Geny hemoglobin człowieka
Human globin genes
Autorzy:
Hryniewicz, Justyna
Gondko, Roman
Powiązania:
https://bibliotekanauki.pl/articles/945038.pdf
Data publikacji:
1986
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Źródło:
Acta Universitatis Lodziensis. Folia Biochimica et Biophysica; 1986, 4
0208-614X
Pojawia się w:
Acta Universitatis Lodziensis. Folia Biochimica et Biophysica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of fenugreek seed supplementation on Hemoglobin and PCV among 20-30 years old females: a pilot study
Autorzy:
MP, Brundha
Powiązania:
https://bibliotekanauki.pl/articles/2203253.pdf
Data publikacji:
2022-05-04
Wydawca:
Gdański Uniwersytet Medyczny
Tematy:
Anemia
Hemoglobin
Fenugreek supplementation
PCV
Hematopoietic stem cells
Opis:
BackgroundFemales are more likely than males to suffer from anemia. There have been many studies investigating the nutritional qualities of traditional plants. The of this study was to assess the effect of fenugreek seeds on hemoglobin and PCV values in 20-30 years old females.Material and methodsBaseline hematological tests were obtained from 10 females aged 20-30 years. Supplementation of the standard amount of fenugreek was given to the population. After 48 days the same hematological parameters were analyzed as a post-test. The results of the pre- and post-test analysis were compared by using a paired-sample t-test. Relevant details were also collected and analyzed.ResultsThe mean value of hemoglobin before supplementation (Hb1) and hemoglobin after supplementation (Hb2) was 12.3200 and 11.3300 respectively and the mean value of packed cell volume before (PCV1) and after supplementation (PCV2) was 36.7970 and 35.4700, respectively. This shows that there is a mild decrease in hemoglobin and PCV values after fenugreek supplementation, but not at a statistically significant level.ConclusionsWithin the limitations of our pilot study, we conclude that fenugreek has no significant effect on Hemoglobin and PCV values and can’t be used as an exact supplement to cure anemia.
Źródło:
European Journal of Translational and Clinical Medicine; 2022, 5, 1; 27-32
2657-3148
2657-3156
Pojawia się w:
European Journal of Translational and Clinical Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis of oxygen binding by hemoglobin on the basis of mean intrinsic thermodynamic quantities
Autorzy:
Bordbar, Abdol-Khalegh
Mousavi, Sayed
Dazhampanah, Hamid
Powiązania:
https://bibliotekanauki.pl/articles/1041216.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cooperativity
mean intrinsic Gibbs free energy
linkage phenomena
hemoglobin
Opis:
The binding data for oxygenation of human hemoglobin, Hb, at various temperatures and in the absence and presence of 2,3-diphosphoglycerate, DPG, and inositol hexakis phosphate, IHP, were analyzed for extraction of mean intrinsic Gibbs free energy, ΔGo, enthalpy, ΔHo, and entropy, ΔSo, of binding at various partial oxygen pressures. This method of analysis considers all the protein species present such as dimer and tetramer forms which were not considered by Imai et al. (Imai K et al., 1970, Biochim Biophys Acta 200: 189 - 196) , in their analysis which was based on Adair equation. In this regard, the values of Hill equation parameters were estimated with high precision at all points of the binding curve and used for calculation of ΔGo, ΔHo and ΔSo were also calculated by analysis of ΔGo values at various temperatures using van't Hoff equation. The results represent the enthalpic nature of the cooperativity in Hb oxygenation and the compensation effect of intrinsic entropy. The interpretation of results also to be, into account the decrease of the binding affinity of sites for oxygen in the presence of DPG and IHP without any considerable changes in the site - site interaction (extent of cooperativity). In other words, the interactions between bound ligands, organic phosphates and oxygen, are more due to a decreasing binding affinity and not to the reduction of the cooperative interaction between sites. The results also document the more heterotropic effect of IHP compared to DPG.
Źródło:
Acta Biochimica Polonica; 2006, 53, 3; 563-568
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Technologia produkcji plazmy krwi i hemoglobiny
Blood plasma and hemoglobin production process
Autorzy:
Kowalski, Z.
Makara, A.
Banach, M.
Powiązania:
https://bibliotekanauki.pl/articles/1219892.pdf
Data publikacji:
2011
Wydawca:
Stowarzyszenie Inżynierów i Techników Przemysłu Chemicznego. Zakład Wydawniczy CHEMPRESS-SITPChem
Tematy:
krew zwierzęca
plazma
hemoglobina
proces technologiczny
bilans materiałowy
animal blood
plasma
hemoglobin
technological process
material balance
Opis:
Przedstawiono koncepcję technologiczną produkcji plazmy i hemoglobiny z krwi zwierzęcej opracowaną na podstawie wyników prób i testów, prowadzonych w skali laboratoryjnej i przemysłowej. Sposób prowadzenia procesu technologicznego, oraz dobór aparatów i urządzeń dla instalacji produkcyjnej zależą od asortymentu i jakości wytwarzanych produktów. W przypadku hemoglobiny, możliwe jest uzyskanie produktu ciekłego i suszonego. W przypadku plazmy, można otrzymać plazmę ciekłą, suszoną (nieodbarwioną), suszoną odbarwioną chemicznie. Bilanse materiałowe pozwoliły określić wskaźniki procesu produkcji suszonej plazmy i hemoglobiny. Sporządzono też kalkulacje kosztów produkcji, co pozwoliło na stwierdzenie opłacalności tych produkcji przy oszacowanych nakładach inwestycyjnych.
The paper presents a concept of plasma and hemoglobin production from animal blood developed on the basis of trials and tests performed both on a laboratory and industrial scale. The production process method as well as devices and equipment selected for the production line depend on the range and the quality of products. in the case of hemoglobin it is possible to obtain liquid and dried product, while in the case plasma we can obtain liquid plasma, dried (non-decolorized) and dried chemically decolorized plasma. Material balances allow us to define the indexes for the production of dried plasma and hemoglobin. Production cost estimates have been also prepared, which allows us to show profitability for the production processes at investment outlays assumed.
Źródło:
Chemik; 2011, 65, 5; 466-475
0009-2886
Pojawia się w:
Chemik
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Podstawowe zagadnienia ewolucji hemoglobin
Fundamental questions on the evolution of haemoglobin
Autorzy:
Duchnowicz, Piotr
Duda, Wirgiliusz
Powiązania:
https://bibliotekanauki.pl/articles/945005.pdf
Data publikacji:
1994
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Opis:
The paper presents problems concerning the evolution of haemoglobin. The main stages of Hb evolution: globin gene evolution, formation and solubility of Hb tetramer and functional Hb regulation by allosteric effectors have been presented. The gene duplication, occuring during the formation of fetal and embryonal Hb as well as the evolution rate of vertebrate Hb were discussed. The authors presented the role of exons, introns and pseudogens in the evoluing of globin and discussed the posibility of the acceleration of evolutionary process by means of exon-intron recombinations.
Źródło:
Acta Universitatis Lodziensis. Folia Biochimica et Biophysica; 1994, 10
0208-614X
Pojawia się w:
Acta Universitatis Lodziensis. Folia Biochimica et Biophysica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Suplementacja żelaza u dzieci
Iron supplementation in children
Autorzy:
Siudem, Paweł
Powiązania:
https://bibliotekanauki.pl/articles/2159079.pdf
Data publikacji:
2022-12
Wydawca:
Wydawnictwo Naukowe Medyk sp. z o.o.
Tematy:
żelazo
hemoglobina
suplementacja
hemoglobin
supplementation
iron
Opis:
Żelazo jest jednym z ważniejszych składników mineralnych niezbędnych do prawidłowego funkcjonowania organizmu. Szczególnie istotna jest jego rola w procesie tworzenia hemoglobiny i funkcjonowaniu układu krążenia. Podczas intensywnego wzrostu u dzieci następuje wzrost zapotrzebowania na żelazo dostarczane w diecie. Postać, w jakiej jest spożywane żelazo, ma duże znaczenie dla przyswajalności. Żelazo hemowe pochodzące z produktów odzwierzęcych charakteryzuje się lepszą przyswajalnością. W przypadku problemów z dostarczaniem odpowiedniej ilości dobrze przyswajalnego żelaza można rozważyć jego suplementację.
Iron is one of the most important minerals necessary for the proper functioning of the body. Its role in the process of hemoglobin formation and the functioning of the circulatory system is particularly important. During vigorous growth in children, the need for dietary iron increases. The form in which iron is consumed is of great importance for absorption. Heme iron derived from animal products is characterized by better digestibility. In case of problems with providing the right amount of easily digestible iron, its supplementation may be considered.
Źródło:
Lek w Polsce; 2022, 378, 11; 24-29
2353-8597
Pojawia się w:
Lek w Polsce
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Oxygen affinity of Chironomus thummi thummi haemoglobins
Powinowactwo tlenowe hemoglobin larw Chironomus thummi thummi
Autorzy:
Osmulski, Paweł Aleksander
Powiązania:
https://bibliotekanauki.pl/articles/944998.pdf
Data publikacji:
1988
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Opis:
Z larw czwartego stadium Chironomus thummi thummi wyizolowano białko oddechowe o właściwościach hemoglobiny. Białko to wykazuje wysoki stopień niejednorodności, gdyż metodami elektroforetycznymi i chromatografii jonowymiennej stwierdzono obecność 12 różnych składników w hemolimfie pojedynczej larwy. Zbadano parametry powinowactwa tlenowego mieszaniny składników monomerycznych, dimerycznych, a także mieszaniny wszystkich składników. Podczas wykonywania pomiarów zastosowano układ redukujący podsiarczyn sodu - kwas askorbinowy, ze wzglądu na wysoką stałą szybkości samoutleniania badanych hemoglobin. We wszy stkich zbadanych układach stwierdzono wysokie powinowactwo tlenowe, obecność alkalicznego efektu Bohra i brak kooperatywności wiązania tlenu. Wyniki te zostały przeanalizowane pod kątem fizjologicznego przystosowywania się larw do silnie zeutrofizowanego środowiska wodnego o zmiennych właściwościach tlenowych. Zaproponowano również mechanizm działania układu redukującego w warunkach tlenowych i beztlenowych.
Źródło:
Acta Universitatis Lodziensis. Folia Biochimica et Biophysica; 1988, 6
0208-614X
Pojawia się w:
Acta Universitatis Lodziensis. Folia Biochimica et Biophysica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Glycated hemoglobin, diabetes treatment and cancer risk in type 2 diabetes. A case-control study
Autorzy:
Dabrowski, M.
Powiązania:
https://bibliotekanauki.pl/articles/51962.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Opis:
Introduction: Type 2 diabetes is associated with an increased risk of some types of cancer. Diabetes treatment may also modify cancer risk. Objective: The aim of this retrospective, case-control study was to assess whether HbA1c level and use of anti-diabetic drugs are associated with cancer development in a diabetic population. Materials and methods: The case group consisted of 53 patients who developed cancer after diagnosis of diabetes. They were compared with 53 diabetic subjects without cancer, strictly matched to a case group by age and gender. In both groups – apart from HbA1c and diabetes treatment – demographic data, smoking habits, comorbidities, BMI, diabetes duration, use of aspirin, antihypertensive and hypolipemic drugs were also analyzed. Results: Patients with cancer had a significantly higher mean HbA1c value compared with the control group, 7.83±1.26% vs. 7.30±1.08%, respectively (p=0.022). The distribution of patients in four HbA1c categories (<7.0, 7.0-7.9, 8.0-8.9 and ≥9.0%) was significantly different between the two groups (p=0.031). The probability of cancer was higher among patients with HbA1c value ≥8.0 % OR 3.160 (95% CI 1.342-7.440), p=0.013, and lower among patients using metformin, OR 0.228 (95% CI 0.083-0.633), p=0.006. The number of insulin users, insulin dose, duration of insulin treatment, and use of other anti-diabetic drugs were not significantly different between the two groups. Also, no significant differences were found between the two groups regarding other variables. Conclusions: The presented case-control study indicated an important role of metabolic control and confirmed the protective role of metformin in reducing cancer risk among patients with type 2 diabetes. Contrary to other studies, insulin use was not associated with a higher risk of cancer. Other anti-diabetic drugs appeared to have a neutral impact on cancer development.
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Plant hemoglobins can be maintained in active form by reduced flavins and confer tolerance to nitro-oxidative stress
Autorzy:
Sainz, M.
Perez-Rontome, C.
Ramos, J.
Mulet, J.
James, E.
Becana, M.
Powiązania:
https://bibliotekanauki.pl/articles/81132.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
plant
hemoglobin
nitric oxide
nonsymbiotic hemoglobin
flavin
chloroplast
thylakoid
oxidative stress
methyl viologen
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensitivity enhancement of a wavelength interrogation-based optical fiber surface plasmon resonance sensor for hemoglobin concentration using barium titanate
Autorzy:
Shi, Zhen-Jiang
Guo, Shi-Liang
Li, Xin
Li, Zhi-Quan
Meng, Shu-Han
Li, Chong-Zhen
Powiązania:
https://bibliotekanauki.pl/articles/27310091.pdf
Data publikacji:
2023
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
surface plasmon resonance
wavelength interrogation
barium titanate
sensitivity enhancement
hemoglobin concentration
Opis:
In this paper, the performances of a wavelength interrogation-based optical fiber surface plasmon resonance sensor for hemoglobin (Hb) concentration is investigated by theoretical simulation. The proposed configuration incorporates optical fiber, 70 nm silver, 18 nm barium titanate (BaTiO3), and 2 nm zinc oxide. Simulation results show the sensor exhibits refractive index sensitivity of 4023 nm/RIU and concentration sensitivity of 10.0873 nm/(g∙dL), along with Hb concentration varying from 0 to 14 g/dL. This paper especially focuses on the influence of BaTiO3 on the performances of the proposed sensor with light wavelength ranging from 350 to 1000 nm. Comparison analysis indicates sandwiching 18 nm BaTiO3 between sensing layers not only enhances the concentration sensitivity by 30.14% but also decreases the nonlinear error of the sensor from 0.68% to 0.63%. For a wavelength accuracy of 0.1 nm, the proposed sensor can provide a resolution of 0.0099 g/dL for Hb concentration detection.
Źródło:
Optica Applicata; 2023, 53, 2; 167--184
0078-5466
1899-7015
Pojawia się w:
Optica Applicata
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Association of glycosylated hemoglobin with mortality of patients in intensive care unit: a prospective observation study
Autorzy:
Kumar, Damera Seshi
Wasnik, Seema Balkrishna
Yadav, Amlendu
Yadav, Rupesh
Powiązania:
https://bibliotekanauki.pl/articles/29432036.pdf
Data publikacji:
2024-03-31
Wydawca:
Towarzystwo Pomocy Doraźnej
Tematy:
Glycated hemoglobin
intensive care unit
mortality
Opis:
INTRODUCTION: Glycated hemoglobin (HbA1c) is the most commonly used clinical test to estimate mean blood glucose during the past 2 to 3 months. In addition to diagnostic purposes, the HbA1c level also predicts diabetes complications. The aim of this study was to determine the association of glycosylated hemoglobin with mortality in intensive care unit (ICU). MATERIALS AND METHODS: A prospective observational study was conducted in the ICU with a total of 281 patients. These patients were classified into two groups based on their HbA1c levels: one group with HbA1c level < 6.5 % and another group with HbA1c level ≥ 6.5%. The following data were collected during the study period. Clinical details and scores such as the APACHE II score (Acute Physiology and Chronic Health Assessment) and daily SOFA (Sequential Organ Failure Assessment) scores for the period of stay in the ICU. ICU morbidities as the need for mechanical ventilation, the use of inotropes / vasopressors, the length of stay in the ICU, and the requirement of renal replacement therapy (RRT). The outcome measures were ICU mortality and 28-day mortality. RESULTS: Of 281 patients admitted to the ICU for more than 48 hours, 157 patients (55.9%) had HbA1c levels < 6.5%, with the remaining 124 (44.1%) had levels ≥ 6.5%. ICU mortality was present in 107 (38.07%) cases. ICU mortality was higher in patients in the HbA1c ≥ 6.5% group compared to the HbA1c < 6.5% group. This was statistically significant (p-value <0.001). Mortality at 28 days was observed in 125 (44.48%) cases. Patients with an HbA1c value ≥ 6.5%, there was a higher mortality at 28 days compared to patients with an HbA1c value < 6.5%. This was found to be statistically significant (p-value <0.001). CONCLUSIONS: The study showed that glycated hemoglobin levels (HbA1c) levels ≥ 6.5% had a significantly higher mortality rate compared to the patient in the HbA1c level < 6.5%.
Źródło:
Critical Care Innovations; 2024, 7, 1; 24-33
2545-2533
Pojawia się w:
Critical Care Innovations
Dostawca treści:
Biblioteka Nauki
Artykuł

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