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Tytuł:
Effects of gelatine-coated vascular grafts on human neutrophils
Autorzy:
Mayer, Frank
Buerger, Thomas
Halloul, Zuhir
Lippert, Hans
König, Brigitte
Tautenhahn, Joert
Powiązania:
https://bibliotekanauki.pl/articles/1394409.pdf
Data publikacji:
2015
Wydawca:
Index Copernicus International
Tematy:
biocompatibility
gelatine
vascular grafts
human neutrophils
Opis:
The aim of the study was to investigate the immune-modulatory potential of commercially available PTFE and polyester vascular grafts with and without gelatine-coating. The biomaterial-cell-interaction was characterized by changes of established parameters such as PMN-related receptors/mediators, phagocytosis potential and capacity as well as the effect of an additional plasma-dependent modulation. Material and methods. By means of a standardized experimental in vitro model, various vascular graft material (PTFE/polyester/uncoated/gelatine-coated) was used for incubation with or without plasma and co-culturing with human neutrophile granulocytes (PMN) followed by analysis of representative receptors and mediators (CD62L, CD11b, CXCR2, fMLP-R, IL-8, Elastase, LTB4 ). Oxidative burst assessed phagocytosis capacity. Results. Comparing the vascular grafts, un-coated PTFE induced the lowest magnitude of cell stimulation whereas in case of gelatine-coating, cell response exceeded those of the other vascular grafts. This was also found comparing the polyester-based prosthetic material. Gelatine-coated polyester led to a more pronounced release of elastase than gelatine- coated PTFE and the uncoated materials. The results of oxidative burst indicated a reduced phagocytosis capacity in case of gelatine-coated polyester. Plasma incubation did also provide an impact on the cellular response. While in case of gelatinecoating, PMN-related receptor stimulation became lower, it increased by native polyester. The latter one did also induce more mediators such as IL-8 and LTB4 than gelatine-coated material. Conclusions. There have been no extensive data on cell-cell interactions, cytokines and general histo-/hemocompatibility of human cells by the new generation of vascular grafts. It remains still open whether healing process and infectious resistance can be compromised by material-dependent overstimulation or reduced phagocytosis potential of the immune cells of the primary unspecific immune response induced by gelatine-coated materials.
Źródło:
Polish Journal of Surgery; 2015, 87, 9; 443-452
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Indications and Long-term Outcomes of Open Augmentation Rhinoplasty with Autogenous L-shaped Costal Cartilage Strut Grafts – A Single Plastic Surgeon’s Experience
Autorzy:
Leach, Laura
Shamil, Eamon
Malata, Charles M
Powiązania:
https://bibliotekanauki.pl/articles/1398127.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
augmentation rhinoplasty
costal cartilage grafts
autoimmune inflammatory disease
granulomatosis with polyangiitis
relapsing polychondritis
screw fixation of grafts
Opis:
Introduction: We present a single surgeon’s experience of open augmentation rhinoplasty with autogenous
L-shaped costal cartilage grafts, with long-term patient-reported outcome data. We highlight the salient operative steps and outline the peri-operative care required to optimise outcomes. Materials and Methods: A retrospective review of eleven such augmentation rhinoplasties performed between 2008 and 2016 was undertaken. Indications included saddle nose deformity [granulomatosis with polyangiitis (n=7) and relapsing polychondritis (n=1)], post-traumatic nasal collapse (n=1) and advanced cosmetic westernisation of the nose (n=2). Long-term patient-reported outcome was assessed with a patient questionnaire. Results: All patients achieved marked improvement in nasal position, shape and function. There was no cartilage exposure, warping or resorption and no recurrent deformities. One patient’s dorsal graft was fractured two years later during an ophthalmological procedure and the deformity was re-corrected successfully, again with the above technique. Average follow up was 5.2 years. Of the nine patients who responded to the follow-up questionnaire, 100% were satisfied with their nasal appearance. 100% of responders at follow-up reported that they have had no problems relating to their nose (n=9). Discussion: L-shaped costal cartilage grafts provided a reliable, reproducible approach in augmentation rhinoplasty for disparate indications (inflammatory, traumatic and cosmetic) in the hands of a low-volume operator. With careful patient selection and planning, this technique can provide pleasing aesthetic outcomes and high patient satisfaction, with good long-term outcomes.
Źródło:
Polish Journal of Otolaryngology; 2018, 72, 3; 26-32
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Autogenous transplants of adrenal fragments in an animal model
Autorzy:
Dworzyńska, Agnieszka
Paduszyńska, Katarzyna
Pomorski, Lech
Powiązania:
https://bibliotekanauki.pl/articles/1392426.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
grafts
transplantation
adrenal insufficiency
adrenal gland
Opis:
Introduction: Adrenal insufficiency is a typical complication after surgical treatment of adrenal tumors, especially after the removal of both adrenal glands. Human beings are not able to survive without adrenal glands and without proper hormonal substitution. Autotransplantation of a fragment of the adrenal gland may prevent this complication. This can be done by transplanting the entire adrenal glands or its fragment, such as the adrenal cortex cells. In the case of adrenal tumors, the entire adrenal gland can not be transplanted. However, it is possible to transplant cells from the tumor-free part. Successful adrenal autografts may result in a new treatment of adrenal insufficiency. Materials and Methods: Autograft transplantation was performed on 3 groups of Sprague Dawley rats. In the first group, physiological corticosterone concentrations were determined. These animals were not operated. In the second group, both adrenal glands were removed. Corticosterone concentrations were determined after bilateral adrenalectomy. The third group was divided into two parts. In the first subgroup, bilateral adrenalectomy was performed simultaneously with adrenal transplant into the omentum. In the second subgroup, right adrenalectomy was performed simultaneously with and adrenal transplant into the omentum followed a month later by left adrenalectomy. During the experiment, corticosterone concentrations were measured at 4 time points. Results: The statistical difference between corticosterone concentrations in rats after two timed adrenalectomies and rats after bilateral adrenalectomy was statistically different, but these results were far from physiological concentrations.
Źródło:
Polish Journal of Surgery; 2018, 90, 4; 22-28
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Szczepy rosnące w drzewostanie sosny zwyczajnej (Pinus sylvestris L.)
Grafts growing in the Scotch pine (Pinus sylvestris L.) stand
Autorzy:
Wesoly, W.
Pazdrowski, W.
Buczma, D.
Powiązania:
https://bibliotekanauki.pl/articles/791510.pdf
Data publikacji:
2013
Wydawca:
Wyższa Szkoła Zarządzania Środowiskiem w Tucholi
Źródło:
Zarządzanie Ochroną Przyrody w Lasach; 2013, 07
2081-1438
2391-4106
Pojawia się w:
Zarządzanie Ochroną Przyrody w Lasach
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Przeciwbakteryjne właściwości protez naczyniowych modyfikowanych cefepimem
Antibacterial properties of vascular grafts modified with cefepime
Autorzy:
Miazga-Karska, M.
Ginalska, G.
Powiązania:
https://bibliotekanauki.pl/articles/284918.pdf
Data publikacji:
2007
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
protezy naczyniowe
cefepim
vascular prosthesis
cefepime
Źródło:
Engineering of Biomaterials; 2007, 10, no. 67-68; 19-20
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Flowering and cone bearing of Picea abies grafts in second-generation seed orchards
Autorzy:
Misiorny, A
Chalupka, W.
Powiązania:
https://bibliotekanauki.pl/articles/41542.pdf
Data publikacji:
2006
Wydawca:
Polska Akademia Nauk. Instytut Dendrologii PAN
Tematy:
Norway spruce
Picea abies
cone yield
seed production
flowering
seed orchard
Opis:
In 2004, abundant flowering of Norway spruce (Picea abies (L.) Karst.) was observed in two second- generation seed orchards: (1) ‘Outbreeding’, promoting crossing between clones of five geographically distant populations; and (2) ‘Kolonowskie’, restoring a population whose offspring exists only in an international experiment (IUFRO 1964/1968). In bothseed orchards, female strobili were produced by 91.3% and 91.7% of clones, represented by 64.1% and 55.5% of grafts, respectively, and statistically significant differences between clones were found in the number of mature cones. In the case of the seed orchard ‘Outbreeding’, the number of mature cones in individual clones was significantly correlated with latitude of the origin of maternal populations (r = 0.8826, p = 0.0470). The majority (95%) of cones in seed orchards ‘Outbreeding’ and ‘Kolonowskie’ were produced by only 28.2% and 38.5% of all clones, and 21.4% and 25.7% of all grafts, respectively. These data attest to a disparity between the level of genetic diversity in seed orchard progeny resulting from the observed numbers of cone-bearing clones and grafts and the genetic diversity expected from the actual participation of clones and grafts in seed orchard composition. The estimated seed production per 1 ha of seed orchard area in 2004 reached 21.05 kg for ‘Outbreeding’ and 21.72 kg for ‘Kolonowskie’.
Źródło:
Dendrobiology; 2006, 56; 51-59
1641-1307
Pojawia się w:
Dendrobiology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wpływ warunków oświetlenia wewnątrz pączków na zawartość endogennych substancji giberelinopodobnych u szczepów sosny zwyczajnej
The influence of light conditions inside buds on the content of endogenous gibberellin-like substances in grafts of Scots pine
Autorzy:
Wesoly, W.
Powiązania:
https://bibliotekanauki.pl/articles/818949.pdf
Data publikacji:
1987
Wydawca:
Polskie Towarzystwo Leśne
Źródło:
Sylwan; 1987, 131, 01
0039-7660
Pojawia się w:
Sylwan
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Optimized protocol of anesthesia in large experimental model of transgenic pigs for treatment of cartilage injuries with new generation biomaterials and cell-based grafts in vivo
Autorzy:
Wieczorek, J.
Jura, J.
Mierzwiński, M.
Ficek, K.
Kuźma, A.
Powiązania:
https://bibliotekanauki.pl/articles/285461.pdf
Data publikacji:
2018
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
cartilage
biomaterials
treatment
Źródło:
Engineering of Biomaterials; 2018, 21, 148; 55
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mandibular reconstruction : biomechanical strength analysis (FEM) based on a retrospective clinical analysis of selected patients
Autorzy:
Jędrusik-Pawłowska, M.
Kromka-Szydek, M.
Katra, M.
Niedzielska, I.
Powiązania:
https://bibliotekanauki.pl/articles/306994.pdf
Data publikacji:
2013
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
bone grafts
mandibular reconstruction
finite element method
reconstruction plates
bone healing
kości
metoda elementów skończonych
przeszczep kostny
Opis:
Restoration of mandible discontinuity defects continues as a challenge for maxillofacial surgeons. Despite the development of algorithms for reconstruction plates fixation and autogenous grafting techniques, complications are still encountered including screw loosening, bone resorption or delayed/incomplete union. The aim of the study was to analyze the possibility of obtaining bone union in the aspect of biomechanical conditions of two mandible reconstructions using an autogenous iliac crest bone graft stabilized with a reconstruction plate, and to attempt to predict patient outcomes based on strength parameters obtained by the finite element analysis. The authors of the present paper were trying to determine to what extent the reconstruction model and changes occurring in hard tissues of the bone and autogenous graft (simulated by changes in material properties) might help predict individual patient courses. The effort of reconstruction plates was defined using the values of the von Mises stress (σHMH) while the effort of bones was determined based on the values of strain intensity εint. The results of the above mentioned simulations are presented in the form of bar graphs and strain/stress distribution maps. Our strength analyses indicate that uncomplicated healing of grafts fixed with reconstruction plates requires that the initial loading of the stomatognatic system should not result in strain intensity exceeding 20–40 [×10–4]. This range of strain intensity evokes an increase in the mineral phase. The state of nonunion between the mandibular bone and the graft might result from prolonged periods of insufficient loading of the mandible during treatment.
Źródło:
Acta of Bioengineering and Biomechanics; 2013, 15, 2; 23-31
1509-409X
2450-6303
Pojawia się w:
Acta of Bioengineering and Biomechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ocena stabilności zamocowania sztucznej panewki stawu biodrowego
Fixing stability assessment of artificial acetabulum of a hip joint
Autorzy:
Płomiński, J.
Watral, Z.
Michalski, A.
Sienkiewicz, J.
Powiązania:
https://bibliotekanauki.pl/articles/327444.pdf
Data publikacji:
2006
Wydawca:
Polska Akademia Nauk. Polskie Towarzystwo Diagnostyki Technicznej PAN
Tematy:
protezoplastyka rewizyjna
staw biodrowy
przeszczep kostny
panewka stawu biodrowego
revision hip arthroplasty
bone grafts
acetabulum of a hip joint
Opis:
W referacie przedstawiono problematykę stabilności zamocowania panewki sztucznego stawu biodrowego po zabiegu rewizyjnym. Wykonano badania eksperymentalne na modelach cielęcego stawu biodrowego z zacementowaną na warstwie ubitych przeszczepów kostnych panewką polietylenową. Po zacementowaniu panewki obciążano ją siłą 1kN przez 100000 cykli a następnie sprawdzano jej stabilność przykładając na jej krawędź siłę ścinającą. Badano wpływ grubości warstwy przeszczepów oraz kierunku działania siły obciążającej na stabilność panewki.
The paper deals with the problem of stability of artificial acetabulum after revision hip arthroplasty. Experimental tests on calf joint with artificial acetabulum cemented into it were performed. Cemented acetabulum was subjected to a cyclic load of 1 kN through 100000 cycles and then the fixing stability was verified by applying a shearing force to its edge. The influence of thickness of bone grafts layer and the direction of loading force on the overall stability was investigated.
Źródło:
Diagnostyka; 2006, 3(39); 245-252
1641-6414
2449-5220
Pojawia się w:
Diagnostyka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mechanical guidelines on the properties of human healthy arteries in the design and fabrication of vascular grafts: experimental tests and quasi-linear viscoelastic model
Autorzy:
Faturechi, Rahim
Hashemi, Ata
Abolfathi, Nabiollah
Solouk, Atefeh
Powiązania:
https://bibliotekanauki.pl/articles/307007.pdf
Data publikacji:
2019
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
elastyczność
model konstytutywny
tętnica
elasticity
constitutive model
human artery
artificial artery
quasi-linear viscoelasticity
Opis:
Knowledge of mechanical behavior of healthy human arteries as the guidelines to target properties of vascular grafts deserves special attention. There is a lack of mathematical model to characterize mechanical behavior of biomaterial while many mathematical models to reflect mechanics of human arteries have been proposed. The objective of this paper was set to measure mechanical properties of healthy human arteries including Common Carotid Artery (CCA), Abdominal Aorta Artery (AAA), Subclavian Artery (SA), Common Iliac Artery (CIA) and Right and Left Iliac Artery (RIA and LIA) and compare them to those of commercial ePTFE and Dacron®. Methods: Series of stress relaxation and strain to failure tests vere performed on all samples. The experimental data was utilized to develop quasi-linear viscoelastic (QLV) model of both natural and artificial arteries. Results: ePTFE is the stiffest sample, while the CCA is the most compliant one among all. RIA and CIA are more viscous than the other natural arteries, while AA and CCA are less viscous. The proposed model demonstrated an accurate fit to the experimental results, a proof of its ability to model both nonlinear elasticity and viscoelasticity of the human arteries and commercial ones. Conclusions: ePTFE and Dacron® are much stiffer than human arteries that may lead to the disruption of blood hemodynamic and may not be biomechanically feasible as a replacement.
Źródło:
Acta of Bioengineering and Biomechanics; 2019, 21, 3; 13-21
1509-409X
2450-6303
Pojawia się w:
Acta of Bioengineering and Biomechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Die-back of grafts in the clonal seed orchards of Douglas-fir (Pseudotsuga menziensii (Mirb.) Franco) in Poland and attempts at producing seedlings of this species by autovegetative propagation
Autorzy:
Kuss, M
Powiązania:
https://bibliotekanauki.pl/articles/41152.pdf
Data publikacji:
2002
Wydawca:
Polska Akademia Nauk. Instytut Dendrologii PAN
Tematy:
rooting
autovegetative propagation
Polska
grafting
clonal seed orchard
seedling
Pseudotsuga menziesii
Douglas fir
vegetative propagation
Opis:
So far, experience in the existing clonal seed orchards of Douglas-fir indicates that grafts of this species are short-lived. According to research carried out in North America, incompatibility between the grafted scions and the rootstocks happens during the whole period of growth and development in clonal seed orchards of Douglas-fir. A similar phenomenon occurs in the clonal seed orchards of Douglas-fir in Poland. The extent of die-back of grafts was examined in three existing oldest units in the Forest District of Gniewkowo (founded in 1992-1993; 2.80 ha), the Forest District of Leżajsk (founded in 1995, 4.22 ha) and the Forest District of Łopuchówko (founded in 1993, 7.43 ha). In all these areas, losses due to die-back ranged from a dozen to a few dozen per cent. Die-backs in the clonal seed orchards in the Forest District of Gniewkowo and in the Forest District of Łopuchówko are now reduced to as much as about fourty per cent of grafts. Analyses of die-back in all these areas reveal great variation between individual clones, indicating its genetic basis. Research carried out so far has not demonstrated the presence of any pathogens responsible for causing the die-back in the grafts. Some hope to solve the problem mentioned above arises from attempts at autovegetative propagation of Douglas-fir.
Źródło:
Dendrobiology; 2002, 47 Supplement
1641-1307
Pojawia się w:
Dendrobiology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of the impact of decellularization and sterilization on tensile strength transgenic porcinedermal dressings
Autorzy:
Joszko, Kamil
Gzik-Zroska, Βożena
Kowalewska, Edyta
Klama-Baryła, Agnieszka
Suchoń, Sławomir
Burkacki, Michał
Wolański, Wojciech
Powiązania:
https://bibliotekanauki.pl/articles/307164.pdf
Data publikacji:
2019
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
tkanka skórna
oparzenie
analiza statystyczna
rekonstrukcja
skin tissue
burn wounds treatment
xenogeneic grafts
static tensile test
statistical analysis
reconstructive surgery
Opis:
The aim of this paper was to evaluate which method of acellularization and sterilization is optimal, in the meaning of which processes have the least impact on the deterioration of mechanical properties of porcine tissues used for xenogeneic applications. Methods: The static tensile probe was conducted for 80 skin specimens obtained from transgenic swine, which are used as a wound dressing for skin recipient. Obtained data were subsequently analyzed with the use of statistical methods. Results: It was found that Young’s modulus for the samples after the sterilization process for the dispase substance and the mixed method (SDS + trypsin) were statistically significantly changed. In the case of dispase, Young’s modulus value before the sterilization process was 12.4 MPa and after the value increased to 28.0 MPa. For the mixed method (SDS + trypsin) before the sterilization process Young’s modulus value was 5.6 MPa and after it was increased to 6.3 MPa. The mixed method (SDS + trypsin) had the slightest effect on changing the mechanical properties of the samples before and after the sterilization process. Conclusions: It was confirmed that different methods of acellularization and the process of sterilization have an influence on the change of mechanical properties of the skin of transgenic swine. In the authors’ opinion, the mixed method (SDS + trypsin) should be recommended as the best one for the preparation of transgenic porcine dermal dressings because it ensures a smaller probability of dressing’s damage during a surgical procedure.
Źródło:
Acta of Bioengineering and Biomechanics; 2019, 21, 3; 87-97
1509-409X
2450-6303
Pojawia się w:
Acta of Bioengineering and Biomechanics
Dostawca treści:
Biblioteka Nauki
Artykuł

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