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Wyszukujesz frazę "dihydropyridine" wg kryterium: Wszystkie pola

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    Wyświetlanie 1-7 z 7
    Tytuł:
    Synthesis and thermal decomposition study of some dihydropyridine derivatives
    Autorzy:
    Baluja, Shipra
    Talaviya, Rahul
    Powiązania:
    https://bibliotekanauki.pl/articles/1192993.pdf
    Data publikacji:
    2016
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    differential scanning calorimetry
    dihydropyridine derivatives
    thermo gravimetric analysis
    Opis:
    Some new dihydropyridine derivatives have been synthesized and their characterization was done by FT-IR, 1H NMR and Mass spectral data. Thermal analysis of these dihydropyridine derivatives have been carried out by thermao gravimetric (TG), differential thermal analysis (DTA) and differential scanning calorimetry (DSC) techniques. Further, from thermograms of these compounds, various kinetic parameters such as order of reaction (n), energy of activation (E), frequency factor (A) and entropy change (∆S) have been evaluated. The obtained results indicates that thermal stability of dihydropyridine derivatives have been depend on the type of substituent present in the compounds.
    Źródło:
    World Scientific News; 2016, 39; 1-16
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Dihydropyridine receptors functioning as voltage sensors in cardiac myocytes
    Autorzy:
    Mackiewicz, U.
    Emanuel, K.
    Lewartowski, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/70889.pdf
    Data publikacji:
    2000
    Wydawca:
    Polskie Towarzystwo Fizjologiczne
    Tematy:
    dihydropyridine receptor
    calcium
    cardiac myocyte
    guinea pig
    voltage sensor
    heart
    skeletal muscle
    Źródło:
    Journal of Physiology and Pharmacology; 2000, 51, 4,2
    0867-5910
    Pojawia się w:
    Journal of Physiology and Pharmacology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Microwave Assisted Fast Synthesis of CuO Nanoflakes: Catalytic Application in the Synthesis of 1,4-Dihydropyridine
    Autorzy:
    Bajaj, S.
    Tekade, P.
    Lakhotiya, G.
    Borkar, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/1032600.pdf
    Data publikacji:
    2017-10
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    microwave irradiation
    CuO nanoflakes
    catalyst
    dihydropyridine
    Opis:
    CuO nanoflakes were successfully synthesized by microwave irradiation, using copper(II) sulphate and sodium hydroxide (NaOH) as the starting materials and ethanol as the solvent. The CuO nanoflakes were characterized by using techniques such as X-ray powder diffraction, field emission scanning electron microscopy, and UV-visible absorption spectroscopy, Fourier transform infra-red spectroscopy. The synthesized CuO nanoflakes were found to have morphology like nanoflakes with narrow size distribution and high purity. Moreover, the synthesized CuO nanoflakes were used as an efficient catalyst for synthesis of a series of dihydropyridine derivatives. Optimization studies with different catalysts and solvents reveal that CuO nanoparticle in the water/ethanol mixture is efficient catalyst/solvent system for the synthesis of dihydropyridine derivative.
    Źródło:
    Acta Physica Polonica A; 2017, 132, 4; 1294-1300
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Agonist of dihydropyridine receptors, BayK8644 depresses excitation-contraction coupling in myocytes of guinea pig heart
    Autorzy:
    Mackiewicz, U.
    Emanuel, K.
    Lewartowski, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/69950.pdf
    Data publikacji:
    2001
    Wydawca:
    Polskie Towarzystwo Fizjologiczne
    Tematy:
    dihydropyridine receptor
    cardiac myocyte
    calcium
    sarcoplasmic reticulum
    excitation-contraction coupling
    guinea pig
    heart
    myocyte
    ryanodine receptor
    Źródło:
    Journal of Physiology and Pharmacology; 2001, 52, 3
    0867-5910
    Pojawia się w:
    Journal of Physiology and Pharmacology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effects of an antimutagen of 1,4-dihydropyridine series on cell survival and DNA damage in L5178Y murine sublines
    Autorzy:
    Dalivelya, O.
    Savina, N.
    Kuzhir, T.
    Buraczewska, I.
    Wojewódzka, M.
    Szumiel, I.
    Powiązania:
    https://bibliotekanauki.pl/articles/146264.pdf
    Data publikacji:
    2006
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    1,4-dihydropyridine
    DNA repair
    neutral comet assay
    L5178Y cells
    cytotoxicity
    radioprotective effect
    Opis:
    In a series of studies it was shown that 1,4-dihydropyridine derivatives (1,4-DHP) show antimutagenic and anticlastogenic properties and accelerate repair of oxidant and ionising radiation generated DNA damage. Here, effects of one of 1,4-DHP compounds (sodium 3,5-bis-ethoxycarbonyl-2,6-dimethyl-1,4-dihydropyridine-4-carboxylate denoted as DHP) in X-irradiated L5178Y cells (murine lymphoma sublines, LY-R and LY-S) are reported. DHP treatment 1 h before, during and after X-irradiation gave a radioprotective effect in double strand break (DSB) repair competent LY-R cells: there was an increase in post-irradiation proliferation and cell viability as well as a slight acceleration of break rejoining as measured by the neutral comet assay. In the radiosensitive LY-S cells with impaired non-homologous end-joining system, the radioprotective effect was seen as enhanced growth and viability. There was, however, no effect on the DSB repair rate. Notably, there was no dependence of the biological effects on DHP concentration in the range of concentrations studied (1 nM - 100 mM), suggesting an all-or-none effect, as in cellular signaling induction observed in radioadaptation or bystander effect. We assume that DHP acts by decreasing fixation of radiation inflicted DNA damage, among others, by increasing the rate of DNA repair and enhancing the efficiency of checkpoint control. Direct confirmation of this assumption is necessary.
    Źródło:
    Nukleonika; 2006, 51, 3; 141-146
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Regulation of Ca2+ release from internal stores in cardiac and skeletal muscles.
    Autorzy:
    Wrzosek, Antoni
    Powiązania:
    https://bibliotekanauki.pl/articles/1044313.pdf
    Data publikacji:
    2000
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    Ca2+-induced Ca2+ release
    calcium channels
    dihydropyridine receptor
    calcium sparks
    excitation-contraction coupling
    ryanodine receptor
    Opis:
    It is widely accepted that Ca2+ is released from the sarcoplasmic reticulum by a specialized type of calcium channel, i.e., ryanodine receptor, by the process of Ca2+-induced Ca2+ release. This process is triggered mainly by dihydropyridine receptors, i.e., L-type (long lasting) calcium channels, directly or indirectly interacting with ryanodine receptor. In addition, multiple endogenous and exogenous compounds were found to modulate the activity of both types of calcium channels, ryanodine and dihydropyridine receptors. These compounds, by changing the Ca2+ transport activity of these channels, are able to influence intracellular Ca2+ homeostasis. As a result not only the overall Ca2+ concentration becomes affected but also spatial distribution of this ion in the cell. In cardiac and skeletal muscles the release of Ca2+ from internal stores is triggered by the same transport proteins, although by their specific isoforms. Concomitantly, heart and skeletal muscle specific regulatory mechanisms are different.
    Źródło:
    Acta Biochimica Polonica; 2000, 47, 3; 705-723
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis and Characterization of Novel (E)-1-(aylideneamino)-6-(4-methoxyphenyl)-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile derivatives
    Autorzy:
    Khunt, H. R.
    Babariya, J. S.
    Dedakiya, C. D.
    Maniar, C. A.
    Naliapara, Y. T.
    Powiązania:
    https://bibliotekanauki.pl/articles/412535.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    N-amino pyridine
    2-cyanoacetohydrazide
    1,3-diketone
    Opis:
    We have described simple facile method for the synthesis of Novel (E)-1-(aylideneamino)-6-(4-methoxyphenyl)-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile derivatives by using 1,3-diketone as synthon. All the synthesized compounds were characterized by IR, Mass and 1H NMR spectroscopy.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 11, 3; 185-192
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-7 z 7

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