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Wyszukujesz frazę "diabetes type 1" wg kryterium: Wszystkie pola


Tytuł:
IMPORTANCE OF SYMPTOM CONTROL: SELF-REGULATION IN CHILDREN WITH DIABETES TYPE 1 AND ASTHMA
Autorzy:
Fryt, Joanna
Pilecka, Władysława
Smoleń, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/419397.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Źródło:
Studia Psychologiczne (Psychological Studies); 2013, 51, 3
0081-685X
Pojawia się w:
Studia Psychologiczne (Psychological Studies)
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Comparison of nutrition knowledge in patients with type 1 and type 2 diabetes
Autorzy:
Luszczki, E.
Deren, K.
Sobek, G.
Powiązania:
https://bibliotekanauki.pl/articles/3125.pdf
Data publikacji:
2015
Wydawca:
Instytut Medycyny Wsi
Tematy:
comparison
nutrition
knowledge
patient
diabetes type 1
diabetes type 2
human disease
metabolic disease
Opis:
Introduction. Diabetes as a non-infectious chronic metabolic disease is a problem of the contemporary world, including Poland. Behaviour therapy plays an important role in its treatment, i.e. proper diet and regular physical activity. Patient’s knowledge of nutrition principles is also an essential complement to the treatment, reducing the risk of late complications of diabetes. Objective. Assessment of the nutrition knowledge of patients with type 1 and type 2 diabetes. Materials and method. The study involved 300 randomly selected patients from Rzeszów and the surrounding area (135 patients with type 1 diabetes and 165 patients with type 2 diabetes) aged 8–78.The analysis was made using a survey questionnaire prepared by the authors of the study, conducted in the period July – December 2011. Results. The survey revealed that patients with type 1 diabetes have greater nutrition knowledge and knowledge about diabetes than patients with type 2 diabetes. On the other hand, they are less likely to comply with the recommendations of the diet prescribed by a doctor or a dietician. Conclusions. Patients with diabetes, regardless of age, type of diabetes, gender, or disease duration require continuous broadening of diabetes knowledge. Systematic training will teach patients proper eating habits related to their diet and lifestyle.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2015, 09, 1
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Osobowość młodzieży chorej na cukrzycę
The personality of adolescents with diabetes mellitus
Autorzy:
Szymańska, Sylwia
Powiązania:
https://bibliotekanauki.pl/articles/2139249.pdf
Data publikacji:
2000
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Tematy:
diabetes mellitus type 1
adolescents
personality traits
Opis:
The aim of this study was evaluation of personality traits’ differences between adolescents with diabetes (type 1) and their healthy peers. 100 diabetics (age 16–22,17) and 103 healthy adolescents were assessed. They completed Cattell’s the 16 Personality Questionnaire. The diabetics are significantly different from their healthy peers in a factor H (resistance-lack of resistance) and factors of the second degree – introversion–extraversion and worry–integration. Girls with diabetes are different from healthy girls in a factor C (emotionally stability–neurosis). The diabetics are less resistant to stress, have bigger difficulty in making social contacts, are more shy and anxiously. The girls with diabetes are more neurotic than the healthy girls.
Źródło:
Acta Universitatis Lodziensis. Folia Psychologica; 2000, 04; 57-65
2353-4842
Pojawia się w:
Acta Universitatis Lodziensis. Folia Psychologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Parity does not affect diabetes complications in women with type 1 diabetes
Autorzy:
Cypryk, K.
Grycewicz, J.
Świerzewska, P.
Kosiński, M.
Lewiński, A.
Żurawska-Klis, M.
Powiązania:
https://bibliotekanauki.pl/articles/2081577.pdf
Data publikacji:
2018
Wydawca:
Instytut Medycyny Wsi
Tematy:
diabetes
obstetric history
chronic complications
Opis:
Introduction. The problem concerning the impact of pregnancy on diabetic complications is a matter for discussion as there is some evidence suggesting that pregnancy may trigger development or progression of diabetic chronic complications. However, currently available data concerning this issue is still controversial. Objective. The aim of the study was to evaluate the impact of obstetric history on the development of chronic microangiopatic and macroangiopatic complications in type 1 diabetic women. Materials and Method. The retrospective study comprised 226 white Caucasian type 1 diabetic women, including 190 parous and 36 nulliparous women. Anthropometric data, information concerning the course of the disease, including metabolic control and chronic complications, together with obstetric history, were registered. Results. Parous women were older (p<0.001), but did not differ significantly regarding metabolic control in the course of the disease (p>0.05) and diabetes duration (p>0.05) from nulliparous subjects. There were no significant differences in the incidence (p>0.05) nor onset (p>0.05) of chronic diabetes complications between the groups. The number of deliveries did not correlate with either the incidence nor the onset of chronic complications. Longer DM duration at the moment of first delivery was related to the higher incidence of retinopathy (p<0.01), nephropathy (p<0.05) and neuropathy (p<0.001). Conclusions. The incidence of chronic diabetic complications does not differ between parous women and the subjects that were never pregnant, and is not related to the number of pregnancies.
Źródło:
Annals of Agricultural and Environmental Medicine; 2018, 25, 1; 114-119
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Relationship with peers of young school-aged children with type 1 diabetes
Autorzy:
Ledwon, E.
Szlenk-Czyczerska, E.
Gawlik, M.
Powiązania:
https://bibliotekanauki.pl/articles/1769.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:
child
school child
human development
human disease
diabetes mellitus type 1
parent
Opis:
Background: Functioning in a peer group plays an important role in child development. Building self-esteem of children depends on many factors such as physical health, self-evaluation of their physical performance, academic achievement, social support, family relationships, as well as relationships with peers and teachers. Importance of contacts with peers increases during school-age. At this time children are not able to reject the opinion of other people and subject their behaviour completely to the expectations of their peers. When the need for emotional contact is not satisfied, the complex of being different appears. Isolation within group causes a sense of inferiority, the child becomes passive and resigned. Children, who are chronically ill, rejected or isolated often follow negative emotions in their actions, they become aggressive towards other children or do not want to continue learning. Often the decision about an individual teaching plan results in further isolation of the child. The child’s position in the peer group affects the developing personality, self-confidence and self-esteem. Aim of the study: The aim of the study was to determine the interpersonal relationships of young school-aged children with type 1 diabetes in their peer groups. Material and methods: The study was conducted on children with type 1 diabetes and their parents, who are supervised by Clinic of Diabetes, Regional Medical Center in Opole. The research tool used in both groups was a questionnaire consisting of open and closed questions elaborated by the authors of this study. Results: 73% (41) of evaluated children declared that diabetes does not hinder their performance at school. 93% (55) children claimed that they do not hide their condition from their peers. In addition, 61% (34) talk about their illness with their peers and 69% (38) of them can count on their peers’ help in self-control of diabetes. 71.9% (46) of parents of children with type 1 diabetes allow their children to participate in school trips and 68.8% (44) to participate in school competitions. Conclusions: In most children, diabetes does not affect children’s performance at school. They participate in classes, are accepted and liked in their peer group. Chronically ill children should be able to participate in all types of activities as much as their healthy peers. It seems necessary to continue studies on performance of young school-aged children with type 1 diabetes in their peer group.
Źródło:
Medical Science Pulse; 2018, 12, 2
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Znaczenie opieki stomatologicznej w utrzymaniu zdrowia jamy ustnej u dzieci i młodzieży z cukrzycą typu 1
Importance of dental care to maintain oral health of children and youth with type 1 diabetes
Autorzy:
Kuźmiuk, Anna
Marczuk-Kolada, Grażyna
Łuczaj-Cepowicz, Elżbieta
Obidzińska, Marta
Chorzewska, Ewa
Wasilczuk, Urszula
Kierklo, Anna
Szajda, Sławomir D.
Powiązania:
https://bibliotekanauki.pl/articles/2162585.pdf
Data publikacji:
2017-12-05
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
choroba przyzębia
higiena jamy ustnej
próchnica
cukrzyca typu 1
opieka stomatologiczna
wskaźnik leczenia
periodontal disease
oral hygiene
caries
diabetes type 1
dental care
indicator of treatment
Opis:
Wstęp Opieka lekarza stomatologa nad dziećmi i młodzieżą z cukrzycą typu 1 powinna polegać na rzetelnym badaniu jamy ustnej, wczesnej terapii zmian próchnicowych zębów i utrzymaniu wyników leczenia. Można osiągnąć to dzięki regularnemu, zgodnemu ze standardami, wizytami kontrolnymi, oraz stosowaniu się do zaleceń dotyczących profilaktyki choroby próchnicowej i chorób przyzębia. Celem pracy było zbadanie, czy opieka lekarza stomatologa pozwala na zachowanie zdrowia jamy ustnej dzieci i młodzieży z cukrzycą typu 1. Materiał i metody Badaniem stomatologicznym objęto 60 chorych z cukrzycą typu 1 w wieku 7–17 lat oraz 30 zdrowych dzieci i młodzieży w tym samym przedziale wiekowym. Oceniono intensywność próchnicy, efektywność leczenia zachowawczego, stan przyzębia i higienę jamy ustnej. Wyniki Stwierdzono istotnie niższą intensywność próchnicy oraz lepszy stan przyzębia u badanych dzieci i młodzieży z cukrzycą typu 1. Efektywność leczenia zachowawczego była istotnie wyższa u dzieci chorych z uzębieniem mieszanym. Nie wykazano znamiennych różnic w higienie jamy ustnej między porównywanymi grupami. Wnioski Cukrzyca jest czynnikiem ryzyka schorzeń jamy ustnej, dlatego dzieci i młodzież z cukrzycą typu 1 należy objąć szczególnymi działaniami prewencyjnymi i leczniczymi. Głównym celem programu opieki nad dziećmi z cukrzycą insulinozależną jest wczesne zakwalifikowanie ich do grupy wysokiego ryzyka w celu poprawy stanu ogólnego zdrowia jamy ustnej, a tym samym zwiększenia komfortu życia. Właściwa opieka stomatologiczna nad dziećmi i młodzieżą z cukrzycą typu 1 jest warunkiem utrzymania zdrowia jamy ustnej. Med. Pr. 2018;69(1):37–44
Background Dental care for children and youth with type 1 diabetes should rely on reliable examination of the oral cavity, early treatment of dental caries and maintenance of the treatment results. This can be achieved through regular control visits consistent with the standards, and also through following the recommendations for prevention of dental caries and periodontal disease. The aim of the study was to investigate whether dental care allows to preserve good oral health of children and youth with type 1 diabetes. Material and Methods The study included 60 patients with type 1 diabetes, aged 7–17 years, and 30 healthy children and youth within the same age range. There were evaluated intensity of caries, the effectiveness of conservative treatment, periodontal health and oral hygiene. Results The results of examinations showed significantly lower caries prevalence and better periodontal health in the children and youth with type 1 diabetes. The effectiveness of conservative treatment was significantly higher among patients with mixed dentition. There was no significant difference in oral hygiene between the compared groups. Conclusions Diabetes is a risk factor for oral diseases, so children and youth with type 1 diabetes should be provided with special preventive care and curative measures. The main goal of the insulin-dependent diabetes care program is to early classify them to highrisk groups to improve general oral health and thus improve the quality of life. Proper dental care for children and yuoth with type 1 diabetes is a condition to maintain oral health. Med Pr 2018;69(1):37–44
Źródło:
Medycyna Pracy; 2018, 69, 1; 37-44
0465-5893
2353-1339
Pojawia się w:
Medycyna Pracy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Guidelines for the use of physical activity in children with type I diabetes
Autorzy:
Niewiadomska, Monika
Radziyevska, Mariya
Radziyevsky, Pavlo
Powiązania:
https://bibliotekanauki.pl/articles/1054629.pdf
Data publikacji:
2013
Wydawca:
Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
Tematy:
insulin
physical exercise
type 1 diabetes
Opis:
Type 1 diabetes is a metabolic disorder whose treatment depends not only on the administration of insulin and diabetic control, but also on properly applied physical activity to improve insulin sensitivity and thus the patient’s condition. In order to fulfill this role, physical exercise must be systematic and properly administered. An adequate intensity depends on the physical fitness level of the patient, which may be determined in a six-minute walk test. Before a training cycle, the patient should be subjected to basic clinical tests. The intensity of training may be determined by the Karvonen or Strunz formula to precisely specify the training heart rate (60–75% of maximum heart rate, depending on the condition of the individual). Blood sugar levels should be measured before and after the training session, while during exercise a heart rate monitor should be used. All these measures should help prevent the occurrence of adverse effects such as hypoglycemia.
Źródło:
Central European Journal of Sport Sciences and Medicine; 2013, 1, 1; 47-52
2300-9705
2353-2807
Pojawia się w:
Central European Journal of Sport Sciences and Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rola wsparcia społecznego w leczeniu cukrzycy u młodzieży
The role of social support in the treatment of diabetes in youth
Autorzy:
Strzelczyk, Dorota
Szymańska, Sylwia
Powiązania:
https://bibliotekanauki.pl/articles/2139068.pdf
Data publikacji:
2011
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Tematy:
diabetes mellitus type 1
metabolic control
self-control
social support
satisfaction with support
network support
Opis:
The article is a report of studies on the relationship between social support and the effectiveness of treatment for diabetes in youth. The aim of this study was to answer the question whether between patients with different treatment outcome differences in perceived social support. The study were 100-strong group of diabetics aged 16–18 years (50 girls and 50 boys), which has been assigned to groups of varying effectiveness of diabetes management. Adopted two criteria for allocation of subjects into groups: 1) the level of self-control of diabetes measured by the scale of „Treatment of Diabetes”(LC), 2) the degree of metabolic control measured by HbA1c. To measure the social support Sarason’s Social Support Questionnaire was used. Analysis of test results does not reveal significant differences in social support among patients with high and low self-control. In patients with varying degrees of metabolic control of diabetes patients with poor treatment outcome perceive less social support network (p < 0.05), but they are more satisfied with it (p < 0.01) than patients with good control of diabetes. In addition, the length of morbidity of diabetes is moderately, negatively correlated with the network of support and the degree of satisfaction with the aid received.
Źródło:
Acta Universitatis Lodziensis. Folia Psychologica; 2011, 15; 31-43
2353-4842
Pojawia się w:
Acta Universitatis Lodziensis. Folia Psychologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Parents awareness of type 1 diabetes: knowledge status
Autorzy:
Çınar, Derya
Binay Yaz, Şeyda
Powiązania:
https://bibliotekanauki.pl/articles/1918971.pdf
Data publikacji:
2021-06-14
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
Family
children
parent
type 1 diabetes
nursing
Opis:
Purpose: Type 1 diabetes is a common disease in children and teenagers, but it can occur at any age. This study aimed to determine the awareness and knowledge of type 1 diabetes in parents' to diagnose early. Materials and methods: This study is a descriptive type. Data were collected from 1 April to 1 July 2020 date in Turkey. The study sample consisted of 214 parents who accepted to participate in the study and completed the questionnaire were included in the sample. Results: It was found that the knowledge level of the parents participating in the study about type 1 diabetes was close to medium level (6.10±1.89). The study's findings revealed that there are misperceptions about the incidence of type 1 diabetes in parents. Parents are often confused about the reasons for type 1 and type 2 diabetes. Conclusions: In this study, although the knowledge level of the parents about type 1 diabetes is close to medium level, it is below the intermediate level. It is important and necessary for families to know about type 1 diabetes and its symptoms, observe their child or children and diagnose the disease early.
Źródło:
Progress in Health Sciences; 2021, 11(1); 97-103
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Forms of Activities with a Dog as Modern Types of Physical Recreation
Autorzy:
Niewiadomska, Monika
Powiązania:
https://bibliotekanauki.pl/articles/1030579.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
Tematy:
agility
dog sports
physical activity
type 1 diabetes
Opis:
The rapid civilisational development that took place in the second half of the 20th century, and the resulting changes in the conditions and ways of people’s lives brought forth a number of social phenomena, both positive and negative. Physical activities, i.e. any forms of physical effort undertaken voluntarily in leisure time for entertainment and health purposes, contribute greatly to overcoming the dangers of modern civilization. Among these, activities with the participation of a dog are becoming increasingly popular. These activities are exercised by people of all ages in the form of dog sports, as well as for recreational and therapeutic purposes. The aim of the paper is to present various forms of activities with a dog as modern types of physical recreation exercised by people of all ages. Regular exercise with a dog greatly improves the well-being and provides a feeling of harmony and inner peace. It is becoming yet another modern form of activity.
Źródło:
Central European Journal of Sport Sciences and Medicine; 2018, 23, 3; 53-58
2300-9705
2353-2807
Pojawia się w:
Central European Journal of Sport Sciences and Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Paraoxonase-1 activities in children and adolescents with type 1 diabetes mellitus
Autorzy:
Craciun, Elena
Leucuta, Daniel
Rusu, Razvan
David, Bianca
Cret, Victoria
Dronca, Eleonora
Powiązania:
https://bibliotekanauki.pl/articles/1038772.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
paraoxonase-1
lactonase
arylesterase
children
type 1 diabetes mellitus
Opis:
Background: Paraoxonase-1 is an HDL-associated esterase that acts as an anti-atherogenic agent by protecting LDL from oxidation. This study investigates paraoxonase-1 activities in children and adolescents with type 1 diabetes mellitus and possible associations with other biochemical markers. Patients and methods: The study enrolled 82 children and adolescents with type 1 diabetes mellitus and 41 controls with similar age and gender distribution. Serum paraoxonase-1 arylesterase and salt-stimulated paraoxonase activities were assessed by measuring the rates of phenyl acetate and paraoxon hydrolysis, respectively; paraoxonase-1 lactonase activity and oxidized LDL were assessed by a pH-sensitive colorimetric assay and ELISA, respectively. Glycated haemoglobin HbA1c and lipid profile were assayed with an immunoturbidimetric method and commercially available kits, respectively. Results: We found lower paraoxonase-1 activities in diabetics when compared to controls. The decrease was statistically significant only for the lactonase activity, the difference being higher when referring to the subgroup with poor glycaemic control. The lactonase activity/HDL ratio was also lower in diabetics vs. controls, but without statistical significance. Both lactonase and arylesterase activities were negatively correlated with HbA1c in diabetics, but only the latter was statistically significant (ρ = -0.21, P = 0.055; ρ = -0.24, P = 0.03, respectively). A correlation coefficient of ρ = 0.196 (P = 0.078) was found between oxidized LDL and HbA1c. Conclusion: All paraoxonase-1 activities were lower in diabetic children and adolescents, but only the decrease in the lactonase activity was statistically significant. Although lipid profile and glycaemic control were altered in diabetics, no differences were observed between groups regarding oxidized LDL level.
Źródło:
Acta Biochimica Polonica; 2016, 63, 3; 511-515
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Odbiór smaku słonego, słodkiego i umami oraz preferencje pokarmowe dzieci z cukrzycą typu 1 – doniesienie wstępne
Salty, sweet and umami taste perception and food preferences in children with diabetes mellitus type 1 – preliminary report
Autorzy:
Hartman, Magdalena
Deja, Grażyna
Klimacka-Nawrot, Ewa
Bobrowska, Weronika
Suchecka, Wanda
Ejsmond, Agata
Małecka-Tendera, Ewa
Błońska-Fajfrowska, Barbara
Powiązania:
https://bibliotekanauki.pl/articles/1038836.pdf
Data publikacji:
2012
Wydawca:
Śląski Uniwersytet Medyczny w Katowicach
Tematy:
cukrzyca typu 1
smak słony
smak słodki
smak umami
preferencje pokarmowe
gustometria
diabetes mellitus type 1
salty taste
sweet taste
umami taste
food
Opis:
INTRODUCTION Nutrition is a key factor affecting the health of diabetics. The study is an attempt to determine if there are differences in salty, sweet and umami taste perception as well as in food preferences between children with diabetes mellitus type 1, treated for years or more, and their healthy peers. MATERIAL AND METHODS Group C (19 children aged 10–18, average age 15, suffering from diabetes mellitus type 1 with at least a five-year medical history, mean 7.2 ± 2.2 years) and Group K1 (42 healthy children of sex, age and BMI corresponding to those of the children from Group C) were examined for their taste perception of sodium chloride, sucrose and monosodium glutamate by means of specific gustometry. Their food preferences were also studied. The number of healthy children whose food preferences were examined was increased to include 105 participants (Group K2). RESULTS In Group C as compared to Group K1, the percentage of correct taste recognition of sodium chloride was lower (p < 0.05) whereas the percentage of incorrect recognition was higher (p < 0.01). The intensity of sucrose taste perception was lower in Group C than in Group K1 (p < 0.01). Group C as compared to Group K2 liked more the taste of: farinaceous dishes (p < 0.01), pasta (p < 0.05), beef, veal and pork (p < 0.01) and salty snacks (p < 0.01). CONCLUSIONS Children and teenagers affected with diabetes mellitus type 1, display disturbances in their perception of salty and sweet taste. Moreover, their food preferences differ from those of healthy children. It seems reasonable to expand the research program in order to confirm the observed relations. Understanding the relation between taste perception and food preferences in young patients with diabetes mellitus may contribute to composing a tastier and more attractive diet, which is a significant element in therapy.
WSTĘP Sposób odżywiania jest głównym czynnikiem wpływającym na zdrowie osób z cukrzycą. W niniejszej pracy podjęto próbę odpowiedzi na pytanie: czy dzieci i młodzież z cukrzycą typu 1, chorujące przez co najmniej 5 lat, różnią się odbiorem smaku słonego, słodkiego i umami oraz preferencjami pokarmowymi od swoich zdrowych rówieśników. MATERIAŁ I METODY W grupie C (19 dzieci w wieku 10–18 lat, średnio 15 lat, z cukrzycą typu 1, z co najmniej 5-letnią historią choroby, średnio 7,2 ± 2,2 roku) oraz w grupie K1 (42 dzieci zdrowych o odpowiednio dobranej płci, wieku i BMI) wykonano badania odbioru smaku chlorku sodu, sacharozy i glutaminianu sodu metodą gustometrii swoistej oraz zbadano preferencje pokarmowe. Liczbę osób zdrowych objętych badaniem preferencji pokarmowych zwiększono do 105 dzieci (grupa K2). WYNIKI W grupie C, w porównaniu z grupą K1, odsetek prawidłowych rozpoznań smaku chlorku sodu był niższy (p < 0,05), natomiast błędnych rozpoznań wyższy (p < 0,01). Intensywność odbioru smaku sacharozy była niższa w grupie C niż w grupie K1 (p < 0,01). W grupie C bardziej niż w grupie K2 były lubiane: potrawy mączne (p < 0,01), makarony (p < 0,05), wołowina, wieprzowina i cielęcina (p < 0,01) oraz słone przekąski (p < 0,01). WNIOSKI U dzieci i młodzieży chorujących na cukrzycę typu 1 występują zaburzenia percepcji smaków słonego i słodkiego. Również preferencje pokarmowe tych dzieci są nieco inne niż dzieci zdrowych. Zasadne wydaje się rozszerzenie badań w celu potwierdzenia zaobserwowanych zależności. Zrozumienie relacji między percepcją smaku a preferencjami pokarmowymi młodych osób chorych na cukrzycę może przyczynić się do uatrakcyjnienia ich diety, stanowiącej istotny element terapeutyczny.
Źródło:
Annales Academiae Medicae Silesiensis; 2012, 66, 4; 7-16
1734-025X
Pojawia się w:
Annales Academiae Medicae Silesiensis
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Robustness of closed-loop glucose control systems
Autorzy:
Wyciślok, Artur
Śmieja, Jarosław
Powiązania:
https://bibliotekanauki.pl/articles/29432415.pdf
Data publikacji:
2023
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
artificial pancreas
closed-loop control
insulin pump
type 1 diabetes
Opis:
The main purpose of this work is to provide an extensive, simulation-based comparison of robustness of PID and MPC algorithms in control of blood glucose levels in patients with type 1 diabetes and thus answer the question of their safety. Cohort testing, with 1000 simulated, randomized patients allowed to analyze specific control quality indicators, such as number of hypoglycemic events, and length of hypo- and hyperglycemia periods. Results show that both algorithms provide a reasonable safety level, taking into account natural changes of patients’ physiological parameters. At the same time, we point out drawbacks of each solution, as well as general problems arising in close-loop control of blood glucose level.
Źródło:
Archives of Control Sciences; 2023, 33, 3; 681--705
1230-2384
Pojawia się w:
Archives of Control Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
PREDICTING VISUAL PERCEPTION AND WORKING MEMORY DEFICITS AMONG PATIENTS WITH TYPE 1 DIABETES: THE IMPLICATION OF EATING ATTITUDE AND MENTAL HEALTH STATUS
Autorzy:
Samir, Bikri
Hsaini, Asmae
Lababneh, Tamara
Louragli, Ismail
Benmhammed, Hajar
Touhami Ahami, Ahmed Omar
Aboussaleh, Youssef
Powiązania:
https://bibliotekanauki.pl/articles/2138070.pdf
Data publikacji:
2021-12-16
Wydawca:
Fundacja Edukacji Medycznej, Promocji Zdrowia, Sztuki i Kultury Ars Medica
Tematy:
Type 1 diabetes
visual perception
working memory
mental health
eating attitude
Opis:
Several recent studies designate that individuals with type-1-diabetes (T1D) are at higher risk for cognitive impairment than their peers without T1D. The aim of this study was to determine whether socio-demographic and clinical characteristics, eating attitude and psycho-emotional characteristics can predict visual perception (VP) and working memory (WM) impairment in the Moroccan population with T1D. A cross-sectional analysis was carried out in adult T1D patients (N=140). The Rey-Osterrieth Complex Figure test (electronical version) was used to evaluate the VP and WM. Moreover, patients also completed the 21-item Depression, Anxiety, and Stress Scale to assess their mental health state. In order to evaluate the risk of eating disorders the Eating attitudes Test-26 were used. Finally, anthropometric properties and clinical characteristics were evaluated. Predictors of cognitive dysfunction were determined using the hierarchical regression analysis. The major result was that age, long diabetes duration, glycemia, HbA1c, dieting and bulimia were the potential predictors of low scores in VP and WM. Other significant predictors were cholesterol, triglycerides for visual perception. Although psych-emotional symptoms including stress, anxiety, and depression were not a significant predictors of VP and WM impairment. Furthermore, our findings showed that the more the level of stress increases, the VP and WM scores significantly decrease. This study suggests that it can be helpful for medical practitioners to screen for disordered eating behaviors and emotional symptoms as a supplemental risk factor for cognitive impairment in T1D.
Źródło:
Acta Neuropsychologica; 2021, 19(4); 501-519
1730-7503
2084-4298
Pojawia się w:
Acta Neuropsychologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Type III Polyglandular Autoimmune Syndromes in children with type 1 diabetes mellitus
Autorzy:
Ben-Skowronek, I.
Michalczyk, A.
Piekarski, R.
Wysocka-Lukasik, B.
Banecka, B.
Powiązania:
https://bibliotekanauki.pl/articles/49668.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Opis:
Introduction: Type III Polyglandular Autoimmune Syndrome (PAS III) is composed of autoimmune thyroid diseases associated with endocrinopathy other than adrenal insufficiency. This syndrome is associated with organ-specific and organ-nonspecific or systemic autoimmune diseases. The frequency of PAS syndromes in diabetic children is unknown. Objectives: The aim of the study was to evaluate the incidence of PAS III in children with diabetes mellitus type 1. Patients and methods: The study consisted of 461 patients with diabetes mellitus type 1(T1DM), who were 1-19 years of age. TSH, free thyroxin, TPO autoantibodies, and thyroglobulin autoantibodies were determined annually. Autoimmune Hashimoto’s thyroiditis was diagnosed in children with positive tests for TPO Ab and Tg Ab and thyroid parenchymal hypogenicity in the ultrasound investigation. Elevated TSI antibodies were used to diagnose Graves’ disease. Additionally, Anti-Endomysial Antibodies IgA class were determined every year as screening for celiac disease. During clinical control, other autoimmune diseases were diagnosed. Adrenal function was examined by the diurnal rhythm of cortisol. Results: PAS III was diagnosed in 14.5% children: PAS IIIA (T1DM and autoimmune thyroiditis) was recognized in 11.1 % and PAS III C (T1DM and other autoimmune disorders: celiac disease, and JIA, psoriasis and vitiligo) in 3.5% children. PAS IIIA was more prevalent in girls than in boys – 78.4% versus 21.6% (p<0.05). PAS III was observed between 1-5 years of life in 66.6% children; the frequency decreased in consecutive years and successively increased in the adolescence period to 22.7%. Conclusions: PAS III occurs in 14.5% of children with DM type1 and the incidence is positively correlated with patients’ age and female gender. Children with PAS III should be carefully monitored as a group at risk for the development of other autoimmune diseases.
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Limited GADD45α expression and function in IL-1β toxicity towards insulin-producing cells
Autorzy:
Skalniak, Lukasz
Gurgul-Convey, Ewa
Okreglicka, Katarzyna
Skalniak, Anna
Jura, Jolanta
Powiązania:
https://bibliotekanauki.pl/articles/1039450.pdf
Data publikacji:
2013
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
GADD45
IL-1β
insulin-producing cells
type 1 diabetes
Opis:
Growth arrest and DNA damage-inducible (GADD) 45 proteins are regulators of cell death and survival. The proinflammatory cytokine IL-1β strongly increases the level of the transcript encoding GADD45α in rat insulin-producing INS-1E cells. The activation of Gadd45α gene is clearly dependent on JNK and NF-κB activation and the synthesis of the secondary mediator nitric oxide (NO). Interestingly, the observed twelve-fold increase in the GADD45α-coding transcript level is not followed by increased expression of GADD45α at the protein level. An analysis of IL-1β toxicity in INS-1E cells overexpressing GADD45α revealed no correlation between the GADD45α protein level and the sensitivity to IL-1β toxicity. These findings suggest that the potential engagement of GADD45α in IL-1β toxicity towards beta cells is limited to the effects induced by the basal expression level of this protein.
Źródło:
Acta Biochimica Polonica; 2013, 60, 4; 595-602
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Physical activity in type 1 diabetic young and early adults treated with insulin pump therapy. A preliminary report
Autorzy:
Roszkowski, A.
Kulesza, K.
Cybulski, M.
Witkowska, A.M.
Powiązania:
https://bibliotekanauki.pl/articles/1918883.pdf
Data publikacji:
2019-08-26
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
Type 1 diabetes
insulin pump
physical activity
young adults
early adults
IPAQ
Opis:
Purpose: To determine the level of physical activity in young and early adults with type 1 diabetes in comparison with their healthy counterparts and to determine whether the use of insulin pump facilitates physical activity. Materials and methods: This study included 40 type 1 diabetes (T1D) subjects of both sexes treated with a personal insulin pump therapy, and 30 healthy controls. The diagnostic survey included questions about nutrition, knowledge about the disease and whether the patient can control diabetes through physical activity, diet and self-monitoring. The International Physical Activity Questionnaire – long form (IPAQ-L), was used to assess the level of physical activity of both diabetic and control individuals. Results: 87.5% T1D subjects believe that using an insulin pump facilitates their physical activity. The level of physical activity associated with cycling (p=0.038) and vigorous physical activity (p=0.008) was higher in T1D than in the control group. Statistically significant differences (p=0.043) were found for total physical activity. The total mean activity was higher in participants with T1D (8147.70 MET-min/week) compared to the control group (5857.55 MET-min/week). Conclusions: Young and early adults with type 1 diabetes may be more physically active than their healthy counterparts, mainly in their leisure time. The use of a personal insulin pump facilitates physical activity, but most diabetics experience episodes of hypoglycemia after physical activity.
Źródło:
Progress in Health Sciences; 2019, 1; 13-21
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Assessment of diet quality in children and adolescents with type 1 diabetes
Autorzy:
El-Jamal, S.
Elfane, H.
Chamlal, H.
Barakat, I.
Daif, H.
Mziwira, M.
Fassouane, A.
Belahsen, R.
Powiązania:
https://bibliotekanauki.pl/articles/28765556.pdf
Data publikacji:
2022
Wydawca:
Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
Opis:
Background. Micronutrient malnutrition is a serious public health problem in most developing countries, including Morocco, due to poor and therefore lower quality diets that lack dietary diversity. Objective. The present study aimed to assess dietary diversity and variety and their relationship with micronutrient adequacy in children and adolescents with type 1 diabetes (T1D). Materials and methods. A cross-sectional study was carried among 240 children and adolescents with T1D. Weight and height were measured and BMI was calculated. Dietary intake data were obtained from two 24-h recalls. A Dietary diversity (DDS) and dietary variety scores (DVS) and mean adequacy ratio (MAR) and nutritional adequacy ratios (NARs) were calculated and compared according to sociodemographic/anthropometric categories. Results. 52.1% of the patients were female. The mean age of the patients was 8.49 ± 4.1 years. The mean BMI was 19.44 ± 5.24 kg/m2; the mean DDS was 4.62±1.20 and the mean MAR was 0.66 ± 0.11. Older children living in rural areas have a low DDS/DVS. Parental education and income level are associated with DDS/DVS. General and central obesity were significantly elevated in children with high DDS. In addition, a high intake of vegetables, eggs, fiber and micronutrients (Magnesium, Calcium, Potassium, Zinc, Phosphorus and Vit B1) is associated with a high DDS; however, high DVS is associated with high consumption of dairy products, carbohydrates and low intake of protein and fat. There are also positive correlations between DDS/DVS and NARs for various nutrients. Conclusion. The quality of the respondents’ diets are moderately diversified. DDS or DVS can be used as indicators of micronutrient adequacy in Moroccan T1D children. Nutritional education needs to be strengthened to improve dietary diversity in children, especially in rural areas.
Źródło:
Roczniki Państwowego Zakładu Higieny; 2022, 73, 4; 413-422
0035-7715
Pojawia się w:
Roczniki Państwowego Zakładu Higieny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sense of Coherence, Locus of Control and Depression Symptoms in Adolescents with Type 1 Diabetes
Autorzy:
Jankowicz, Sylwia
Puchalska-Wasyl, Małgorzata
Łysiak, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/2125026.pdf
Data publikacji:
2021-11-08
Wydawca:
Katolicki Uniwersytet Lubelski Jana Pawła II. Towarzystwo Naukowe KUL
Tematy:
type 1 diabetes
adolescence
sense of coherence
symptoms of depression
locus of control
Opis:
For patients with type 1 diabetes, sense of coherence (SOC), locus of control (LOC) and depression symptoms seem to be important variables in the context of compliance with a treatment regimen. The aim of this article is to describe the functioning of adolescents with type 1 diabetes—to define the common features and differentiating characteristics of the clinical group in comparison with the control group in terms of SOC, LOC and symptoms of depression. The other aim is to check whether LOC mediates the relationship between SOC and depression symptoms in the diabetics group. The study involved 100 adolescents aged 13–17. The clinical group contained adolescents with type 1 diabetes while the control group featured adolescents without diabetes. Antonovsky’s Sense of Coherence Scale (SOC-29), the Locus of Control Questionnaire (LOCQ) by Krasowicz and Kurzyp-Wojnarska and the Children’s Depression Inventory (CDI) by Kovacs were used. The groups did not differ in their SOC level but varied in the level of depression symptoms and LOC. The clinical and control groups had undetermined and external LOC, respectively. Diabetics also had a lower level of depression symptoms. SOC correlated positively with LOC and negatively with depression symptoms. Additionally, within the clinical group, LOC mediated the relationship between SOC and symptoms of depression. Determining the level of key health variables in type 1 diabetics is important in educating them how to manage their disease. With regard to adolescents without diabetes, the results confirm the need to intensify activities aimed at monitoring their mental state.
Źródło:
Roczniki Psychologiczne; 2021, 24, 2; 105-122
1507-7888
Pojawia się w:
Roczniki Psychologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cure for Type 1 diabetes with biotechnology – How far we are from clinical application?
Autorzy:
Wszoła, Michał
Powiązania:
https://bibliotekanauki.pl/articles/1844860.pdf
Data publikacji:
2021
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Źródło:
Engineering of Biomaterials; 2021, 24, 163; 10
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Physioprophylaxis of type 1 diabetes in children using physical exercise
Fizjoprofilaktyka cukrzycy typu 1 u dzieci z wykorzystaniem aktywności fizycznej
Autorzy:
Zaworski, K.
Ławnik, A.
Kubińska, Z.
Shpakou, A.
Powiązania:
https://bibliotekanauki.pl/articles/2053568.pdf
Data publikacji:
2019
Wydawca:
Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
Tematy:
physioprophylaxis
type 1 diabetes
physical exercise
children
fizjoprofilaktyka
cukrzyca typu 1
aktywność fizyczna
dzieci
Opis:
According to the Physiotherapist Act, physioprophylaxis is an important component of physiotherapy and of the physiotherapist’s professional activities. Physioprophylaxis can be oriented towards practicing healthy lifestyle behaviours, minimizing disease risk factors, or attenuating the consequences of the disease, surgery, and/or disability. Type 1 diabetes is a chronic metabolic disease characterized by hyperglycaemia, i.e. high blood glucose levels. It is caused by the dysfunction or destruction of β cells of pancreatic islets of Langerhans, which are responsible for the production and secretion of insulin. Type 1 diabetes is most common in children and adolescents. According to the 2018 report, 6,400 children aged 0-14 years and about 180,000 people over 14 years old suffer from type 1 diabetes in Poland alone. Physical activity is an important stimulus for optimal physiological development of children and adolescents, and is an important factor in reducing the risk of cardiovascular diseases, cancer, and mortality. Physical exercise reduces the need for insulin and increases the sensitivity of cells to insulin, so that the daily dose of insulin can be reduced. The Polish Diabetes Association recommends that children with type 1 diabetes should exercise for more than one hour a day in order to reduce the risk of vascular complications associated with the disease. The aim of this paper is to examine the effects of type 1 diabetes physioprophylaxis in children in the form of physical exercise, based on previous literature. The majority of research indicates physical activity has a positive effect on physiological function in children with type 1 diabetes, specifically reducing the risk of hypoglycaemia, high blood glucose level, insulin demand, and premature death.
Fizjoprofilaktyka, zgodnie z Ustawą o zawodzie fizjoterapeuty, jest składową fizjoterapii i czynnością zawodową fizjoterapeuty. Może być ukierunkowana na praktykowanie zachowań zdrowotnych, zapobieganie czynnikom ryzyka choroby lub zapobieganie konsekwencjom choroby (operacji) i niepełnosprawności. Cukrzyca typu 1 to przewlekła choroba metaboliczna cechująca się występowaniem hiperglikemii, czyli podwyższonego poziomu glukozy w osoczu krwi. Jej przyczyną jest zaburzenie funkcji lub zniszczenie komórek β wysp Langerhansa trzustki. Cukrzyca typu 1 występuje najczęściej u dzieci i młodzieży. Według raportu z 2018 roku w Polsce na cukrzycę typu 1 choruje 6 400 dzieci w wieku 0-14 lat oraz ok. 180 000 osób powyżej 14 roku życia. Aktywność fizyczna jest ważnym stymulatorem prawidłowego rozwoju dzieci i młodzieży w ujęciu holistycznym, a także istotnym czynnikiem zmniejszania ryzyka chorób układu sercowo-naczyniowego, nowotworów oraz śmiertelności. Wysiłek fizyczny powoduje zmniejszone zapotrzebowanie na insulinę oraz zwiększanie wrażliwości komórek na insulinę, dzięki czemu dawka dobowa insuliny może być zmniejszona. Polskie Towarzystwo Diabetologiczne zaleca podejmowanie wysiłku fizycznego przez dzieci chorujące na cukrzycę typu 1 w wymiarze powyżej jednej godziny dziennie celem redukcji ryzyka powikłań naczyniowych. Celem artykułu jest przedstawienie wyników fizjoprofilaktyki cukrzycy typu 1 u dzieci w formie aktywności fizycznej na podstawie literatury. Większość badań wskazuje pozytywne działanie aktywności fizycznej na stan funkcjonowania dziecka z cukrzycą typu 1 zmniejszając: ryzyko hipoglikemii, stężenie glukozy we krwi, zapotrzebowanie na insulinę i ryzyko śmierci.
Źródło:
Health Problems of Civilization; 2019, 13, 4; 287-295
2353-6942
2354-0265
Pojawia się w:
Health Problems of Civilization
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Dziecko szkolne z cukrzycą typu 1 w opinii studentów wychowania fizycznego
Autorzy:
Ławnik, Anna
Kubińska, Zofia
Pańczuk, Anna
Danielewicz, Jolanta
Powiązania:
https://bibliotekanauki.pl/articles/1504624.pdf
Data publikacji:
2020
Wydawca:
Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
Tematy:
szkoła
dziecko
cukrzyca typu 1
studenci wychowania fizycznego
type 1 diabetes
child
school
physical education students
Opis:
Streszczenie Celem badań było poznanie wiedzy studentów wychowania fizycznego na temat: - cukrzycy typu 1, - sytuacji dziecka z cukrzycą typu 1 w szkole, - udziału dziecka z cukrzycą typu 1 w lekcjach wychowania fizycznego, - obowiązków nauczyciela wychowania fizycznego wobec ucznia z cukrzycą. Materiał i metody Badania przeprowadzono w 2018r. wśród 92 studentów wychowania fizycznego kończących studia na AWF w Białej Podlaskiej. Zastosowano autorski kwestionariusz ankiety. Wyniki Dane przedstawiają wiedzę badanych na tematy związane z uczniem chorym na cukrzycę typu 1. Wnioski Wiedza badanych na temat cukrzycy typu 1 jest na niewystarczającym poziomie. Większość badanych zna sytuację i potrzeby chorego dziecka w szkole. Przekonanie, że dziecko z cukrzycą może uczestniczyć w lekcjach wychowania fizycznego zadeklarowała niespełna połowa studentów. Badani studenci uważają, że nauczyciel wychowania fizycznego powinien umieć zdiagnozować stany zagrażające zdrowiu ucznia z cukrzycą i udzielić mu pomocy oraz zachęcać go do systematycznego uczestnictwa w lekcjach wychowania fizycznego.
Źródło:
Rozprawy Społeczne; 2020, 14, 1; 43-52
2081-6081
Pojawia się w:
Rozprawy Społeczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Clinical factors affecting the perception of hypoglycemia in type 1 diabetes patients treated with personal insulin pumps
Autorzy:
Matejko, B.
Grzanka, M.
Kiec-Wilk, B.
Malecki, M.T.
Klupa, T.
Powiązania:
https://bibliotekanauki.pl/articles/52037.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Opis:
Introduction and Objective. The ability to perceive the symptoms of hypoglycemia during the early decrease in plasma glucose concentration may be critical for the safety of T1DM patients treated with intensive insulin therapy, including those treated with continuous subcutaneous insulin infusion (CSII). In the presented observational study an attempt was made to asses clinical factors that might affect subjective awareness of hypoglycemia in CSII-treated T1DM patients, with special attention to factors specific for this mode of treatment. Materials and Methods. For the purpose of the study, data of 110 CSII-treated T1DM patients were collected (78 females and 32 males). The records were analyzed from glucose meters (200-300 measurements/download, depending on meter type) and insulin pumps (total insulin dose, basal/bolus ratio, number of boluses/day, bolus calculator and dual wave/square bolus usage, continuous glucose monitoring data) from the last 3 years. Results. It was found that the level of subjective hypoglycemia perception inversely correlated with the number of hypoglycemic episodes per 100 measurements, age, duration of diabetes, time on insulin pump, and positively correlated with mean glycemia (n = 98; r = 0.22; p = 0.0286). With respect to CSII-related factors, hypoglycemia perception inversely correlated with the percentage of basal insulin (n = 106; r = -0.20; p = 0.0354). In stepwise regression analysis, independent predictors for impaired hypoglycemia perception were: age β = -0.29 (p = 0.023), duration of diabetes β = -0.24 (p = 0.029) and number of the hypoglycemia episodes for 100 measurements β = -0.33 (p = 0.0005). Conclusions. Risk factors for impaired hypoglycemia perception in CSII-treated patients include those identified previously for the general population of T1DM individuals. In addition, the presented results suggest that a higher basal/bolus ratio may lead to impairment of the ability to perceive early symptoms of hypoglycemia.
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
LADA Diabetes as a Hybrid Disease – a Narrative Review
Cukrzyca LADA jako choroba hybrydowa – przegląd literatury
Autorzy:
Mataczyńska, Anna
Paprocki, Michał
Jurgiel, Jan
Majdowski, Maciej
Wrzosek, Kamil
Lis, Michał
Powiązania:
https://bibliotekanauki.pl/articles/30146459.pdf
Data publikacji:
2023
Wydawca:
Uczelnia Łazarskiego. Oficyna Wydawnicza
Tematy:
LADA
type 1 diabetes
type 2 diabetes
autoimmune diseases
cukrzyca typu 1
cukrzyca typu 2
choroby autoimmunologiczne
Opis:
Latent autoimmune diabetes in adults (LADA) is a common hybrid disease because it combines features of both type 1 and type 2 diabetes. It is a slow-onset autoimmune disease characterized by an initial relative insulin deficiency. Studies to date indicate a clear genetic overlap between LADA and type 1 diabetes. This is related to the variants in the human leukocyte antigen (HLA) region, which encodes main histocompatibility antigens (MHC). Main histocompatibility antigens are responsible for immunoregulatory processes that are impaired in both type 1 diabetes and LADA, leading to immune system disturbances in individuals. Autoantibodies against pancreatic islets are produced, serving as key markers for distinguishing type 1 diabetes and LADA. They are characterized by occurring at a lower level, as a result of which the destruction of the immune system progresses much more slowly. In the etiopathogenesis of this disease, environmental factors and lifestyle play a significant role, which are also associated with the pathogenesis of type 2 diabetes. In most LADA cases, hyperglycemia does not reach levels as high as in type 1 diabetes, whith contributes to the misdiagnosis of it as type 2 diabetes. So far, an optimal treatment for LADA has not been established. Currently, the proposed treatment focuses on achieving good glycemic control and preventing or delaying the onset of complications. Some authors suggest that this effect can be achieved through the early use of insulin as the first-line pharmacotherapy. Emerging oral hypoglycemic agents used in other types of diabetes may also have a role in the treatment of this condition. Hereby, we discuss the possible usage of Continuous Glucose Monitoring (CGM) in this entity for precise real-time control of blood glucose levels. Despite their many advantages, it is important to remember that these systems still require a certain level of user engagement.
Cukrzyca typu LADA (latent autoimmune diabetes in adults) to powszechna choroba o postaci hybrydowej, która łączy w sobie cechy zarówno cukrzycy typu 1, jak i 2 [1]. Jest to choroba autoimmunologiczna rozwijająca się powoli i charakteryzująca się początkowo względnym niedoborem insuliny. Dotychczasowe badania wskazują na genetyczne nakładanie się cukrzyc typu LADA i typu 1. Ma to związek z wariantami w regionie ludzkich antygenów leukocytarnych (human leukocyte antigen, HLA), które kodują główne antygeny zgodności tkankowej (main histocompatibility antigens, MHC) [2, 3, 4]. Antygeny te odpowiadają za procesy immunoregulujące, które zarówno w cukrzycy typu 1, jak i typu LADA są nieprawidłowe, w wyniku czego dochodzi do zaburzeń w obrębie układu odpornościowego. W przebiegu cukrzycy typu LADA wytwarzane są autoprzeciwciała przeciwko wyspom trzustkowym, które są kluczowymi markerami służącymi do rozpoznawania cukrzyc typu 1 oraz typu LADA [5]. Występują one w dość niskim mianie, w wyniku czego destrukcja układu odpornościowego postępuje stosunkowo wolno. Zaobserwowano również, że w etiopatogenezie cukrzycy typu LADA istotne znaczenie wykazują czynniki środowiskowe i styl życia, które również związane są z patogenezą cukrzycy typu 2 [6]. U większości osób z cukrzycą typu LADA hiperglikemia nie osiąga tak dużych wartości, jak w cukrzycy typu 1, co wpływa na błędne rozpoznanie jej jako cukrzycy typu 2. Dotychczas nie ustalono optymalnego leczenia cukrzycy typu LADA, a proponowane leczenie opiera się na próbach uzyskania dobrej kontroli glikemii oraz zapobieganiu lub opóźnianiu wystąpienia powikłań. Efekt ten według niektórych autorów może być uzyskany poprzez wczesne stosowanie insuliny jako pierwszej linii farmakoterapii. Swoje miejsce w leczeniu tej jednostki chorobowej mogą także znaleźć pojawiające się na rynku doustne preparaty hipoglikemizujące stosowane w innych typach cukrzycy. W pracy została poruszona kwestia wykorzystania systemów ciągłego monitorowania glikemii (continuous glucose monitoring, CGM). Służą one do precyzyjnego kontrolowania poziomu glukozy we krwi w czasie rzeczywistym. Mimo ich wielu zalet należy jednak pamiętać, że systemy te nadal wymagają pewnego poziomu zaangażowania użytkownika.
Źródło:
Review of Medical Practice; 2023, XIX, 4; 72-77
2956-4441
2956-445X
Pojawia się w:
Review of Medical Practice
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Assessment of selected food intake frequency in patients with type 1 diabetes treated with personal insulin pumps
Autorzy:
Krzyzowska, S.
Matejko, B.
Kiec-Wilk, B.
Wilk, M.
Malecki, M.
Klupa, T.
Powiązania:
https://bibliotekanauki.pl/articles/875073.pdf
Data publikacji:
2019
Wydawca:
Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
Opis:
Background. It has been established that in Type 1 Diabetes Mellitus (T1DM), regardless of the insulin therapy model used, diet and proper eating habits are still important in the treatment of the disease. The dietary intervention in these patients is aimed at maintaining proper body weight, obtaining target fasting and post meal blood glucose levels, optimizing lipid profiles. Objective. The aim of the study was to assess dietary habits in a homogeneous group of adults with T1DM treated with personal insulin pumps. Material and methods. The study included 141 adult patients (57% women) with type 1 diabetes treated with personal insulin pumps. The surveyed population was characterized by an average age of 25.8 ± 6.2 years, an average duration of diabetes 13.9 ± 6.9 years, and treatment with a personal pump for 8.2 ± 4.1 years and mean BMI 23.0 ± 2.8 g/m2. All were dwellers of south-eastern Poland. The validated KomPAN questionnaire was used to assess the frequency of consumption of individual food products. Results. The mean percentage of HbA1c in the study group was 7.3% [56 mmol/mol]. The mean total cholesterol level was 4.4 mmol/l, HDL - 1.7 mmol/l, LDL - 2.3 mmol/l and triglycerides - 0.8 mmol/l. In the multivariate regression model, no correlation was found between dietary quality parameters and metabolic compensation measured with HbA1c or lipidogram and the place of residence (village, small town, big city). However, there were differences in the quality of the diet depending on the sex. Women were characterized by higher index of a healthy diet (pHDI-10) (26.3 vs 21.4, p=0.005) and lower index of unhealthy diet (nHDI-14) (13.3 vs 18.6, p <0.001) than men. Conclusions. The results of this study clearly suggest, that despite good metabolic control, patients require more education on the choice of healthy product groups.
Wprowadzenie. Uważa się, że w cukrzycy typu 1 (T1DM), niezależnie od zastosowanego modelu insulinoterapii, dieta i prawidłowe nawyki żywieniowe są kluczowe w leczeniu cukrzycy. Stosowanie odpowiedniej diety ma na celu utrzymanie prawidłowej masy ciała, uzyskanie prawidłowego poziomu glukozy we krwi po posiłku, optymalnego profil lipidowy i prawidłowe wartości ciśnienia krwi. Cel. Celem badania była ocena diety i kontrola metaboliczna w homogennej grupie osób dorosłych z T1DM leczonych osobistymi pompami insulinowymi. Materiał i metody: Badaniem objęto 141 dorosłych pacjentów (57% kobiet) z cukrzycą typu 1 leczonych osobistymi pompami insulinowymi. Badana populacja charakteryzowała się średnim wiekiem 25,8 ± 6,2 lat, średnim czasem trwania cukrzycy 13,9 ± 6,9 lat oraz średnim czasem leczenia osobistą pompą przez 8,2 ± 4,1 lat i średnim BMI 23,0 ± 2,8 g / m2. Wszyscy byli mieszkańcami południowo-wschodniej Polski. Walidowany kwestionariusz KomPAN wykorzystano do oceny częstotliwości spożycia poszczególnych produktów spożywczych. Wyniki. Średni odsetek HbA1c w grupie badanej wynosił 7,3% [56 mmol/mol]. Średni poziom całkowitego cholesterolu wynosił 4,4 mmol / l, HDL - 1,7 mmol / l, LDL - 2,3 mmol / l i triglicerydów - 0,8 mmol / l. W modelu regresji wielorakiej nie stwierdzono korelacji między wskaźnikami diety i wyrównaniem metabolicznym mierzonym za pomocą HbA1c lub lipidogramu oraz miejscem zamieszkania (wieś, małe miasteczko, duże miasto). Jednak różnice w jakości diety zależały od płci. Kobiety charakteryzowały się wyższym wskaźnikiem zdrowej diety (pHDI-10) (26,3 vs 21,4, p = 0,005) i niższym wskaźnikiem niezdrowej diety (nHDI-14) (13,3 vs 18,6, p <0,001) niż mężczyźni. Wnioski: Wyniki tego badania wyraźnie wskazują, że pomimo dobrej kontroli metabolicznej pacjenci wymagają większej edukacji w zakresie wyboru zdrowych grup produktów.
Źródło:
Roczniki Państwowego Zakładu Higieny; 2019, 70, 3
0035-7715
Pojawia się w:
Roczniki Państwowego Zakładu Higieny
Dostawca treści:
Biblioteka Nauki
Artykuł

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